8E23

Human DNA polymerase theta in complex with allosteric inhibitor

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0003677	molecular_function	DNA binding
A	0003887	molecular_function	DNA-directed DNA polymerase activity
A	0006260	biological_process	DNA replication
A	0006261	biological_process	DNA-templated DNA replication
D	0003676	molecular_function	nucleic acid binding
D	0003677	molecular_function	DNA binding
D	0003887	molecular_function	DNA-directed DNA polymerase activity
D	0006260	biological_process	DNA replication
D	0006261	biological_process	DNA-templated DNA replication

Functional Information from PROSITE/UniProt

site_id	PS00447
Number of Residues	20
Details	DNA_POLYMERASE_A DNA polymerase family A signature. RqqAKqicYGiiYgmGaksL

Chain	Residue	Details
A	ARG2379-LEU2398

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269|PubMed:25775267, ECO:0007744|PDB:4X0Q

Chain	Residue	Details
A	THR2428
A	GLU2429
D	THR2428
D	GLU2429

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