8DZK

Dbr1 in complex with 5-mer cleavage product

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000375	biological_process	RNA splicing, via transesterification reactions
A	0000398	biological_process	mRNA splicing, via spliceosome
A	0003723	molecular_function	RNA binding
A	0005506	molecular_function	iron ion binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0006397	biological_process	mRNA processing
A	0008270	molecular_function	zinc ion binding
A	0008419	molecular_function	RNA lariat debranching enzyme activity
A	0016787	molecular_function	hydrolase activity
A	0030145	molecular_function	manganese ion binding
A	0046872	molecular_function	metal ion binding
A	0048471	cellular_component	perinuclear region of cytoplasm
B	0000375	biological_process	RNA splicing, via transesterification reactions
B	0000398	biological_process	mRNA splicing, via spliceosome
B	0003723	molecular_function	RNA binding
B	0005506	molecular_function	iron ion binding
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0006397	biological_process	mRNA processing
B	0008270	molecular_function	zinc ion binding
B	0008419	molecular_function	RNA lariat debranching enzyme activity
B	0016787	molecular_function	hydrolase activity
B	0030145	molecular_function	manganese ion binding
B	0046872	molecular_function	metal ion binding
B	0048471	cellular_component	perinuclear region of cytoplasm
C	0000375	biological_process	RNA splicing, via transesterification reactions
C	0000398	biological_process	mRNA splicing, via spliceosome
C	0003723	molecular_function	RNA binding
C	0005506	molecular_function	iron ion binding
C	0005634	cellular_component	nucleus
C	0005737	cellular_component	cytoplasm
C	0006397	biological_process	mRNA processing
C	0008270	molecular_function	zinc ion binding
C	0008419	molecular_function	RNA lariat debranching enzyme activity
C	0016787	molecular_function	hydrolase activity
C	0030145	molecular_function	manganese ion binding
C	0046872	molecular_function	metal ion binding
C	0048471	cellular_component	perinuclear region of cytoplasm
D	0000375	biological_process	RNA splicing, via transesterification reactions
D	0000398	biological_process	mRNA splicing, via spliceosome
D	0003723	molecular_function	RNA binding
D	0005506	molecular_function	iron ion binding
D	0005634	cellular_component	nucleus
D	0005737	cellular_component	cytoplasm
D	0006397	biological_process	mRNA processing
D	0008270	molecular_function	zinc ion binding
D	0008419	molecular_function	RNA lariat debranching enzyme activity
D	0016787	molecular_function	hydrolase activity
D	0030145	molecular_function	manganese ion binding
D	0046872	molecular_function	metal ion binding
D	0048471	cellular_component	perinuclear region of cytoplasm
E	0000375	biological_process	RNA splicing, via transesterification reactions
E	0000398	biological_process	mRNA splicing, via spliceosome
E	0003723	molecular_function	RNA binding
E	0005506	molecular_function	iron ion binding
E	0005634	cellular_component	nucleus
E	0005737	cellular_component	cytoplasm
E	0006397	biological_process	mRNA processing
E	0008270	molecular_function	zinc ion binding
E	0008419	molecular_function	RNA lariat debranching enzyme activity
E	0016787	molecular_function	hydrolase activity
E	0030145	molecular_function	manganese ion binding
E	0046872	molecular_function	metal ion binding
E	0048471	cellular_component	perinuclear region of cytoplasm

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	10
Details	BINDING: BINDING => ECO:0000269|PubMed:27930312, ECO:0000269|PubMed:28504306, ECO:0007744|PDB:5K73, ECO:0007744|PDB:5K77, ECO:0007744|PDB:5K78, ECO:0007744|PDB:5UKI

Chain	Residue	Details
A	CYS14
E	HIS16
A	HIS16
B	CYS14
B	HIS16
C	CYS14
C	HIS16
D	CYS14
D	HIS16
E	CYS14

---

site_id	SWS_FT_FI2
Number of Residues	10
Details	BINDING: BINDING => ECO:0000269|PubMed:25123664, ECO:0000269|PubMed:27930312, ECO:0000269|PubMed:28504306, ECO:0007744|PDB:4PEF, ECO:0007744|PDB:4PEG, ECO:0007744|PDB:4PEH, ECO:0007744|PDB:4PEI, ECO:0007744|PDB:5K73, ECO:0007744|PDB:5K77, ECO:0007744|PDB:5K78, ECO:0007744|PDB:5UKI

Chain	Residue	Details
A	ASP45
E	HIS180
A	HIS180
B	ASP45
B	HIS180
C	ASP45
C	HIS180
D	ASP45
D	HIS180
E	ASP45

---

site_id	SWS_FT_FI3
Number of Residues	15
Details	BINDING: BINDING => ECO:0000269|PubMed:25123664, ECO:0000269|Ref.6, ECO:0007744|PDB:4PEH, ECO:0007744|PDB:8DZK

Chain	Residue	Details
A	LYS59
D	LYS59
D	LYS134
D	HIS156
E	LYS59
E	LYS134
E	HIS156
A	LYS134
A	HIS156
B	LYS59
B	LYS134
B	HIS156
C	LYS59
C	LYS134
C	HIS156

---

site_id	SWS_FT_FI4
Number of Residues	5
Details	BINDING: BINDING => ECO:0000269|PubMed:25123664, ECO:0000269|Ref.6, ECO:0007744|PDB:4PEG, ECO:0007744|PDB:4PEI, ECO:0007744|PDB:8DZK

Chain	Residue	Details
A	ASN90
B	ASN90
C	ASN90
D	ASN90
E	ASN90

---

site_id	SWS_FT_FI5
Number of Residues	5
Details	BINDING: BINDING => ECO:0000269|PubMed:25123664, ECO:0007744|PDB:4PEG, ECO:0007744|PDB:4PEI

Chain	Residue	Details
A	HIS91
B	HIS91
C	HIS91
D	HIS91
E	HIS91

---

site_id	SWS_FT_FI6
Number of Residues	10
Details	BINDING: BINDING => ECO:0000269|PubMed:25123664, ECO:0000269|PubMed:27930312, ECO:0007744|PDB:4PEG, ECO:0007744|PDB:4PEI, ECO:0007744|PDB:5K77, ECO:0007744|PDB:5K78

Chain	Residue	Details
A	GLY201
E	HIS232
A	HIS232
B	GLY201
B	HIS232
C	GLY201
C	HIS232
D	GLY201
D	HIS232
E	GLY201

---

site_id	SWS_FT_FI7
Number of Residues	5
Details	BINDING: BINDING => ECO:0000269|PubMed:25123664, ECO:0000269|PubMed:27930312, ECO:0007744|PDB:4PEG, ECO:0007744|PDB:4PEH, ECO:0007744|PDB:4PEI, ECO:0007744|PDB:5K77, ECO:0007744|PDB:5K78

Chain	Residue	Details
A	ASP205
B	ASP205
C	ASP205
D	ASP205
E	ASP205

---

site_id	SWS_FT_FI8
Number of Residues	10
Details	BINDING: BINDING => ECO:0000269|PubMed:27930312, ECO:0007744|PDB:4PEG, ECO:0007744|PDB:4PEI

Chain	Residue	Details
A	HIS230
E	MET231
A	MET231
B	HIS230
B	MET231
C	HIS230
C	MET231
D	HIS230
D	MET231
E	HIS230

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