8DXP
Structure of LRRC8C-LRRC8A(IL125) Chimera, Class 3
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3374 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000255 |
| Chain | Residue | Details |
| A | MET1-PRO22 | |
| E | PHE342-GLU803 | |
| F | MET1-PRO22 | |
| F | PHE342-GLU803 | |
| G | MET1-PRO22 | |
| G | PHE342-GLU803 | |
| A | PHE342-GLU803 | |
| B | MET1-PRO22 | |
| B | PHE342-GLU803 | |
| C | MET1-PRO22 | |
| C | PHE342-GLU803 | |
| D | MET1-PRO22 | |
| D | PHE342-GLU803 | |
| E | MET1-PRO22 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 560 |
| Details | TRANSMEM: Helical => ECO:0000255 |
| Chain | Residue | Details |
| A | TRP23-CYS43 | |
| C | TYR126-PHE146 | |
| C | VAL267-VAL287 | |
| C | PHE321-LEU341 | |
| D | TRP23-CYS43 | |
| D | TYR126-PHE146 | |
| D | VAL267-VAL287 | |
| D | PHE321-LEU341 | |
| E | TRP23-CYS43 | |
| E | TYR126-PHE146 | |
| E | VAL267-VAL287 | |
| A | TYR126-PHE146 | |
| E | PHE321-LEU341 | |
| F | TRP23-CYS43 | |
| F | TYR126-PHE146 | |
| F | VAL267-VAL287 | |
| F | PHE321-LEU341 | |
| G | TRP23-CYS43 | |
| G | TYR126-PHE146 | |
| G | VAL267-VAL287 | |
| G | PHE321-LEU341 | |
| A | VAL267-VAL287 | |
| A | PHE321-LEU341 | |
| B | TRP23-CYS43 | |
| B | TYR126-PHE146 | |
| B | VAL267-VAL287 | |
| B | PHE321-LEU341 | |
| C | TRP23-CYS43 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 791 |
| Details | TOPO_DOM: Extracellular => ECO:0000255 |
| Chain | Residue | Details |
| A | THR44-LYS125 | |
| E | GLN288-SER320 | |
| F | THR44-LYS125 | |
| F | GLN288-SER320 | |
| G | THR44-LYS125 | |
| G | GLN288-SER320 | |
| A | GLN288-SER320 | |
| B | THR44-LYS125 | |
| B | GLN288-SER320 | |
| C | THR44-LYS125 | |
| C | GLN288-SER320 | |
| D | THR44-LYS125 | |
| D | GLN288-SER320 | |
| E | THR44-LYS125 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 7 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | SER177 | |
| B | SER176 | |
| C | SER177 | |
| D | SER178 | |
| E | SER177 | |
| F | SER178 | |
| G | SER178 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 7 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q498T9 |
| Chain | Residue | Details |
| A | SER177 | |
| B | SER176 | |
| C | SER177 | |
| D | SER178 | |
| E | SER177 | |
| F | SER178 | |
| G | SER178 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 14 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN64 | |
| E | ASN70 | |
| F | ASN64 | |
| F | ASN70 | |
| G | ASN64 | |
| G | ASN70 | |
| A | ASN70 | |
| B | ASN64 | |
| B | ASN70 | |
| C | ASN64 | |
| C | ASN70 | |
| D | ASN64 | |
| D | ASN70 | |
| E | ASN64 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 7 |
| Details | MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:Q80WG5 |
| Chain | Residue | Details |
| A | THR176 | |
| B | THR176 | |
| C | THR176 | |
| D | THR177 | |
| E | THR176 | |
| F | THR177 | |
| G | THR177 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 7 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q80WG5 |
| Chain | Residue | Details |
| A | SER177 | |
| B | SER176 | |
| C | SER177 | |
| D | SER178 | |
| E | SER177 | |
| F | SER178 | |
| G | SER178 |
