8DXP
Structure of LRRC8C-LRRC8A(IL125) Chimera, Class 3
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 3388 |
Details | TOPO_DOM: Cytoplasmic => ECO:0000269|PubMed:36897307, ECO:0007744|PDB:8DXN, ECO:0007744|PDB:8DXO, ECO:0007744|PDB:8DXP, ECO:0007744|PDB:8DXQ, ECO:0007744|PDB:8DXR |
Chain | Residue | Details |
A | MET1-PRO22 | |
E | TRP340-GLU803 | |
F | MET1-PRO22 | |
F | TRP340-GLU803 | |
G | MET1-PRO22 | |
G | TRP340-GLU803 | |
A | TRP340-GLU803 | |
B | MET1-PRO22 | |
B | TRP340-GLU803 | |
C | MET1-PRO22 | |
C | TRP340-GLU803 | |
D | MET1-PRO22 | |
D | TRP340-GLU803 | |
E | MET1-PRO22 |
site_id | SWS_FT_FI2 |
Number of Residues | 168 |
Details | TRANSMEM: Helical; Name=1 => ECO:0000269|PubMed:36897307, ECO:0007744|PDB:8DXN, ECO:0007744|PDB:8DXO, ECO:0007744|PDB:8DXP, ECO:0007744|PDB:8DXQ, ECO:0007744|PDB:8DXR |
Chain | Residue | Details |
A | TRP23-VAL47 | |
B | TRP23-VAL47 | |
C | TRP23-VAL47 | |
D | TRP23-VAL47 | |
E | TRP23-VAL47 | |
F | TRP23-VAL47 | |
G | TRP23-VAL47 |
site_id | SWS_FT_FI3 |
Number of Residues | 735 |
Details | TOPO_DOM: Extracellular => ECO:0000269|PubMed:36897307, ECO:0007744|PDB:8DXN, ECO:0007744|PDB:8DXO, ECO:0007744|PDB:8DXP, ECO:0007744|PDB:8DXQ, ECO:0007744|PDB:8DXR |
Chain | Residue | Details |
A | MET48-ALA124 | |
E | SER285-HIS314 | |
F | MET48-ALA124 | |
F | SER285-HIS314 | |
G | MET48-ALA124 | |
G | SER285-HIS314 | |
A | SER285-HIS314 | |
B | MET48-ALA124 | |
B | SER285-HIS314 | |
C | MET48-ALA124 | |
C | SER285-HIS314 | |
D | MET48-ALA124 | |
D | SER285-HIS314 | |
E | MET48-ALA124 |
site_id | SWS_FT_FI4 |
Number of Residues | 133 |
Details | TRANSMEM: Helical; Name=2 => ECO:0000269|PubMed:36897307, ECO:0007744|PDB:8DXN, ECO:0007744|PDB:8DXO, ECO:0007744|PDB:8DXP, ECO:0007744|PDB:8DXQ, ECO:0007744|PDB:8DXR |
Chain | Residue | Details |
A | LYS125-PHE144 | |
B | LYS125-PHE144 | |
C | LYS125-PHE144 | |
D | LYS125-PHE144 | |
E | LYS125-PHE144 | |
F | LYS125-PHE144 | |
G | LYS125-PHE144 |
site_id | SWS_FT_FI5 |
Number of Residues | 147 |
Details | TRANSMEM: Helical; Name=3 => ECO:0000269|PubMed:36897307, ECO:0007744|PDB:8DXN, ECO:0007744|PDB:8DXO, ECO:0007744|PDB:8DXP, ECO:0007744|PDB:8DXQ, ECO:0007744|PDB:8DXR |
Chain | Residue | Details |
A | VAL263-VAL284 | |
B | VAL263-VAL284 | |
C | VAL263-VAL284 | |
D | VAL263-VAL284 | |
E | VAL263-VAL284 | |
F | VAL263-VAL284 | |
G | VAL263-VAL284 |
site_id | SWS_FT_FI6 |
Number of Residues | 168 |
Details | TRANSMEM: Helical; Name=4 => ECO:0000269|PubMed:36897307, ECO:0007744|PDB:8DXN, ECO:0007744|PDB:8DXO, ECO:0007744|PDB:8DXP, ECO:0007744|PDB:8DXQ, ECO:0007744|PDB:8DXR |
Chain | Residue | Details |
A | LEU315-TYR339 | |
B | LEU315-TYR339 | |
C | LEU315-TYR339 | |
D | LEU315-TYR339 | |
E | LEU315-TYR339 | |
F | LEU315-TYR339 | |
G | LEU315-TYR339 |
site_id | SWS_FT_FI7 |
Number of Residues | 7 |
Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163 |
Chain | Residue | Details |
A | SER177 | |
B | SER176 | |
C | SER177 | |
D | SER178 | |
E | SER177 | |
F | SER178 | |
G | SER178 |
site_id | SWS_FT_FI8 |
Number of Residues | 7 |
Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q498T9 |
Chain | Residue | Details |
A | SER177 | |
B | SER176 | |
C | SER177 | |
D | SER178 | |
E | SER177 | |
F | SER178 | |
G | SER178 |
site_id | SWS_FT_FI9 |
Number of Residues | 14 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
Chain | Residue | Details |
A | ASN64 | |
E | ASN70 | |
F | ASN64 | |
F | ASN70 | |
G | ASN64 | |
G | ASN70 | |
A | ASN70 | |
B | ASN64 | |
B | ASN70 | |
C | ASN64 | |
C | ASN70 | |
D | ASN64 | |
D | ASN70 | |
E | ASN64 |
site_id | SWS_FT_FI10 |
Number of Residues | 7 |
Details | MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:Q80WG5 |
Chain | Residue | Details |
A | THR176 | |
B | THR176 | |
C | THR176 | |
D | THR177 | |
E | THR176 | |
F | THR177 | |
G | THR177 |
site_id | SWS_FT_FI11 |
Number of Residues | 7 |
Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q80WG5 |
Chain | Residue | Details |
A | SER177 | |
B | SER176 | |
C | SER177 | |
D | SER178 | |
E | SER177 | |
F | SER178 | |
G | SER178 |