8DSL
Peptidylglycine alpha hydroxylating monooxygenase, Q272E
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0005507 | molecular_function | copper ion binding |
| A | 0006518 | biological_process | peptide metabolic process |
| A | 0016020 | cellular_component | membrane |
| A | 0016715 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004497 | molecular_function | monooxygenase activity |
| B | 0005507 | molecular_function | copper ion binding |
| B | 0006518 | biological_process | peptide metabolic process |
| B | 0016020 | cellular_component | membrane |
| B | 0016715 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen |
Functional Information from PROSITE/UniProt
| site_id | PS00084 |
| Number of Residues | 8 |
| Details | CU2_MONOOXYGENASE_1 Copper type II, ascorbate-dependent monooxygenases signature 1. HHMllFgC |
| Chain | Residue | Details |
| A | HIS107-CYS114 |
| site_id | PS00085 |
| Number of Residues | 13 |
| Details | CU2_MONOOXYGENASE_2 Copper type II, ascorbate-dependent monooxygenases signature 2. HvFayrvHTHhlG |
| Chain | Residue | Details |
| A | HIS235-GLY247 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:10504734, ECO:0007744|PDB:1OPM, ECO:0007744|PDB:3PHM |
| Chain | Residue | Details |
| A | HIS107 | |
| B | HIS242 | |
| B | HIS244 | |
| B | MET314 | |
| A | HIS108 | |
| A | HIS172 | |
| A | HIS242 | |
| A | HIS244 | |
| A | MET314 | |
| B | HIS107 | |
| B | HIS108 | |
| B | HIS172 |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 7 |
| Details | M-CSA 135 |
| Chain | Residue | Details |
| A | HIS107 | metal ligand |
| A | HIS108 | hydrogen bond donor, metal ligand, single electron acceptor, single electron donor, single electron relay |
| A | GLN170 | hydrogen bond acceptor, single electron acceptor, single electron donor, single electron relay |
| A | HIS172 | metal ligand |
| A | HIS242 | metal ligand |
| A | HIS244 | metal ligand |
| A | MET314 | metal ligand |
| site_id | MCSA2 |
| Number of Residues | 7 |
| Details | M-CSA 135 |
| Chain | Residue | Details |
| B | HIS107 | metal ligand |
| B | HIS108 | hydrogen bond donor, metal ligand, single electron acceptor, single electron donor, single electron relay |
| B | GLN170 | hydrogen bond acceptor, single electron acceptor, single electron donor, single electron relay |
| B | HIS172 | metal ligand |
| B | HIS242 | metal ligand |
| B | HIS244 | metal ligand |
| B | MET314 | metal ligand |
