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8DR1

Consensus closed state of RFC:PCNA bound to a 3' ss/dsDNA junction (DNA2)

Functional Information from GO Data
ChainGOidnamespacecontents
A0000278biological_processmitotic cell cycle
A0003677molecular_functionDNA binding
A0003689molecular_functionDNA clamp loader activity
A0005515molecular_functionprotein binding
A0005524molecular_functionATP binding
A0005634cellular_componentnucleus
A0005663cellular_componentDNA replication factor C complex
A0006260biological_processDNA replication
A0006261biological_processDNA-templated DNA replication
A0006271biological_processDNA strand elongation involved in DNA replication
A0006272biological_processleading strand elongation
A0006281biological_processDNA repair
A0006298biological_processmismatch repair
A0016887molecular_functionATP hydrolysis activity
A0051301biological_processcell division
B0000077biological_processDNA damage checkpoint signaling
B0003677molecular_functionDNA binding
B0003689molecular_functionDNA clamp loader activity
B0005515molecular_functionprotein binding
B0005524molecular_functionATP binding
B0005634cellular_componentnucleus
B0005663cellular_componentDNA replication factor C complex
B0005829cellular_componentcytosol
B0006260biological_processDNA replication
B0006261biological_processDNA-templated DNA replication
B0006271biological_processDNA strand elongation involved in DNA replication
B0006272biological_processleading strand elongation
B0006281biological_processDNA repair
B0007062biological_processsister chromatid cohesion
B0007064biological_processmitotic sister chromatid cohesion
B0016887molecular_functionATP hydrolysis activity
B0031389cellular_componentRad17 RFC-like complex
B0031390cellular_componentCtf18 RFC-like complex
B0031391cellular_componentElg1 RFC-like complex
B0090618biological_processDNA clamp unloading
C0000077biological_processDNA damage checkpoint signaling
C0003677molecular_functionDNA binding
C0003689molecular_functionDNA clamp loader activity
C0005515molecular_functionprotein binding
C0005524molecular_functionATP binding
C0005634cellular_componentnucleus
C0005663cellular_componentDNA replication factor C complex
C0005829cellular_componentcytosol
C0006260biological_processDNA replication
C0006261biological_processDNA-templated DNA replication
C0006271biological_processDNA strand elongation involved in DNA replication
C0006272biological_processleading strand elongation
C0006281biological_processDNA repair
C0006298biological_processmismatch repair
C0007064biological_processmitotic sister chromatid cohesion
C0016887molecular_functionATP hydrolysis activity
C0031389cellular_componentRad17 RFC-like complex
C0031390cellular_componentCtf18 RFC-like complex
C0031391cellular_componentElg1 RFC-like complex
C0090618biological_processDNA clamp unloading
D0000076biological_processDNA replication checkpoint signaling
D0000077biological_processDNA damage checkpoint signaling
D0003677molecular_functionDNA binding
D0003689molecular_functionDNA clamp loader activity
D0005515molecular_functionprotein binding
D0005524molecular_functionATP binding
D0005634cellular_componentnucleus
D0005663cellular_componentDNA replication factor C complex
D0006260biological_processDNA replication
D0006261biological_processDNA-templated DNA replication
D0006271biological_processDNA strand elongation involved in DNA replication
D0006272biological_processleading strand elongation
D0006281biological_processDNA repair
D0006298biological_processmismatch repair
D0007062biological_processsister chromatid cohesion
D0007064biological_processmitotic sister chromatid cohesion
D0016887molecular_functionATP hydrolysis activity
D0031389cellular_componentRad17 RFC-like complex
D0031390cellular_componentCtf18 RFC-like complex
D0031391cellular_componentElg1 RFC-like complex
D0090618biological_processDNA clamp unloading
E0000077biological_processDNA damage checkpoint signaling
E0003677molecular_functionDNA binding
E0003689molecular_functionDNA clamp loader activity
E0005515molecular_functionprotein binding
E0005524molecular_functionATP binding
E0005634cellular_componentnucleus
E0005663cellular_componentDNA replication factor C complex
E0006260biological_processDNA replication
E0006261biological_processDNA-templated DNA replication
E0006271biological_processDNA strand elongation involved in DNA replication
E0006272biological_processleading strand elongation
E0006281biological_processDNA repair
E0007062biological_processsister chromatid cohesion
E0007064biological_processmitotic sister chromatid cohesion
E0016887molecular_functionATP hydrolysis activity
E0031389cellular_componentRad17 RFC-like complex
E0031390cellular_componentCtf18 RFC-like complex
E0031391cellular_componentElg1 RFC-like complex
E0090618biological_processDNA clamp unloading
F0000278biological_processmitotic cell cycle
F0000710biological_processmeiotic mismatch repair
F0000781cellular_componentchromosome, telomeric region
F0003677molecular_functionDNA binding
F0005515molecular_functionprotein binding
F0005634cellular_componentnucleus
F0005657cellular_componentreplication fork
F0006260biological_processDNA replication
F0006272biological_processleading strand elongation
F0006273biological_processlagging strand elongation
F0006275biological_processregulation of DNA replication
F0006281biological_processDNA repair
F0006289biological_processnucleotide-excision repair
F0006298biological_processmismatch repair
F0006301biological_processpostreplication repair
F0007064biological_processmitotic sister chromatid cohesion
F0019985biological_processtranslesion synthesis
F0030337molecular_functionDNA polymerase processivity factor activity
F0030466biological_processsilent mating-type cassette heterochromatin formation
F0031509biological_processsubtelomeric heterochromatin formation
F0034087biological_processestablishment of mitotic sister chromatid cohesion
F0035753biological_processmaintenance of DNA trinucleotide repeats
F0042802molecular_functionidentical protein binding
F0043626cellular_componentPCNA complex
F0045739biological_processpositive regulation of DNA repair
F0045740biological_processpositive regulation of DNA replication
F0051054biological_processpositive regulation of DNA metabolic process
F0070987biological_processerror-free translesion synthesis
G0000278biological_processmitotic cell cycle
G0000710biological_processmeiotic mismatch repair
G0000781cellular_componentchromosome, telomeric region
G0003677molecular_functionDNA binding
G0005515molecular_functionprotein binding
G0005634cellular_componentnucleus
G0005657cellular_componentreplication fork
G0006260biological_processDNA replication
G0006272biological_processleading strand elongation
G0006273biological_processlagging strand elongation
G0006275biological_processregulation of DNA replication
G0006281biological_processDNA repair
G0006289biological_processnucleotide-excision repair
G0006298biological_processmismatch repair
G0006301biological_processpostreplication repair
G0007064biological_processmitotic sister chromatid cohesion
G0019985biological_processtranslesion synthesis
G0030337molecular_functionDNA polymerase processivity factor activity
G0030466biological_processsilent mating-type cassette heterochromatin formation
G0031509biological_processsubtelomeric heterochromatin formation
G0034087biological_processestablishment of mitotic sister chromatid cohesion
G0035753biological_processmaintenance of DNA trinucleotide repeats
G0042802molecular_functionidentical protein binding
G0043626cellular_componentPCNA complex
G0045739biological_processpositive regulation of DNA repair
G0045740biological_processpositive regulation of DNA replication
G0051054biological_processpositive regulation of DNA metabolic process
G0070987biological_processerror-free translesion synthesis
H0000278biological_processmitotic cell cycle
H0000710biological_processmeiotic mismatch repair
H0000781cellular_componentchromosome, telomeric region
H0003677molecular_functionDNA binding
H0005515molecular_functionprotein binding
H0005634cellular_componentnucleus
H0005657cellular_componentreplication fork
H0006260biological_processDNA replication
H0006272biological_processleading strand elongation
H0006273biological_processlagging strand elongation
H0006275biological_processregulation of DNA replication
H0006281biological_processDNA repair
H0006289biological_processnucleotide-excision repair
H0006298biological_processmismatch repair
H0006301biological_processpostreplication repair
H0007064biological_processmitotic sister chromatid cohesion
H0019985biological_processtranslesion synthesis
H0030337molecular_functionDNA polymerase processivity factor activity
H0030466biological_processsilent mating-type cassette heterochromatin formation
H0031509biological_processsubtelomeric heterochromatin formation
H0034087biological_processestablishment of mitotic sister chromatid cohesion
H0035753biological_processmaintenance of DNA trinucleotide repeats
H0042802molecular_functionidentical protein binding
H0043626cellular_componentPCNA complex
H0045739biological_processpositive regulation of DNA repair
H0045740biological_processpositive regulation of DNA replication
H0051054biological_processpositive regulation of DNA metabolic process
H0070987biological_processerror-free translesion synthesis
Functional Information from PROSITE/UniProt
site_idPS00293
Number of Residues19
DetailsPCNA_2 Proliferating cell nuclear antigen signature 2. RCDHpvtLgmdLtSLsKIL
ChainResidueDetails
FARG61-LEU79

site_idPS01251
Number of Residues24
DetailsPCNA_1 Proliferating cell nuclear antigen signature 1. GIiAqAVDdSRVlLVsLeIgveaF
ChainResidueDetails
FGLY34-PHE57

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues57
DetailsDNA_BIND: DNA_BIND => ECO:0000255
ChainResidueDetails
FARG61-ARG80
GARG61-ARG80
HARG61-ARG80
EARG231
DARG229
CARG206

site_idSWS_FT_FI2
Number of Residues3
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO) => ECO:0000269|PubMed:15166219
ChainResidueDetails
FLYS127
GLYS127
HLYS127

site_idSWS_FT_FI3
Number of Residues6
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate => ECO:0000269|PubMed:12226657
ChainResidueDetails
ASER40
FLYS164
GLYS164
HLYS164

site_idSWS_FT_FI4
Number of Residues1
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:19779198
ChainResidueDetails
ATHR63

219869

PDB entries from 2024-05-15

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