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8DJB

MthK-A90L mutant in closed state with 0 Ca2+

Functional Information from GO Data
ChainGOidnamespacecontents
A0005886cellular_componentplasma membrane
A0006813biological_processpotassium ion transport
A0008324molecular_functionmonoatomic cation transmembrane transporter activity
A0034220biological_processmonoatomic ion transmembrane transport
A0042802molecular_functionidentical protein binding
A0046872molecular_functionmetal ion binding
A0098655biological_processmonoatomic cation transmembrane transport
B0005886cellular_componentplasma membrane
B0006813biological_processpotassium ion transport
B0008324molecular_functionmonoatomic cation transmembrane transporter activity
B0034220biological_processmonoatomic ion transmembrane transport
B0042802molecular_functionidentical protein binding
B0046872molecular_functionmetal ion binding
B0098655biological_processmonoatomic cation transmembrane transport
C0005886cellular_componentplasma membrane
C0006813biological_processpotassium ion transport
C0008324molecular_functionmonoatomic cation transmembrane transporter activity
C0034220biological_processmonoatomic ion transmembrane transport
C0042802molecular_functionidentical protein binding
C0046872molecular_functionmetal ion binding
C0098655biological_processmonoatomic cation transmembrane transport
D0005886cellular_componentplasma membrane
D0006813biological_processpotassium ion transport
D0008324molecular_functionmonoatomic cation transmembrane transporter activity
D0034220biological_processmonoatomic ion transmembrane transport
D0042802molecular_functionidentical protein binding
D0046872molecular_functionmetal ion binding
D0098655biological_processmonoatomic cation transmembrane transport
E0005886cellular_componentplasma membrane
E0006813biological_processpotassium ion transport
E0008324molecular_functionmonoatomic cation transmembrane transporter activity
E0034220biological_processmonoatomic ion transmembrane transport
E0042802molecular_functionidentical protein binding
E0046872molecular_functionmetal ion binding
E0098655biological_processmonoatomic cation transmembrane transport
F0005886cellular_componentplasma membrane
F0006813biological_processpotassium ion transport
F0008324molecular_functionmonoatomic cation transmembrane transporter activity
F0034220biological_processmonoatomic ion transmembrane transport
F0042802molecular_functionidentical protein binding
F0046872molecular_functionmetal ion binding
F0098655biological_processmonoatomic cation transmembrane transport
G0005886cellular_componentplasma membrane
G0006813biological_processpotassium ion transport
G0008324molecular_functionmonoatomic cation transmembrane transporter activity
G0034220biological_processmonoatomic ion transmembrane transport
G0042802molecular_functionidentical protein binding
G0046872molecular_functionmetal ion binding
G0098655biological_processmonoatomic cation transmembrane transport
H0005886cellular_componentplasma membrane
H0006813biological_processpotassium ion transport
H0008324molecular_functionmonoatomic cation transmembrane transporter activity
H0034220biological_processmonoatomic ion transmembrane transport
H0042802molecular_functionidentical protein binding
H0046872molecular_functionmetal ion binding
H0098655biological_processmonoatomic cation transmembrane transport
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues232
DetailsTOPO_DOM: Cytoplasmic
ChainResidueDetails
AMET1-ALA20
HGLU96-LEU106
GMET1-ALA20
GGLU96-LEU106
CMET1-ALA20
CGLU96-LEU106
EMET1-ALA20
EGLU96-LEU106
AGLU96-LEU106
BMET1-ALA20
BGLU96-LEU106
DMET1-ALA20
DGLU96-LEU106
FMET1-ALA20
FGLU96-LEU106
HMET1-ALA20

site_idSWS_FT_FI2
Number of Residues160
DetailsTRANSMEM: Helical; Name=Outer helix M1
ChainResidueDetails
ATHR21-ILE41
BTHR21-ILE41
DTHR21-ILE41
FTHR21-ILE41
HTHR21-ILE41
GTHR21-ILE41
CTHR21-ILE41
ETHR21-ILE41

site_idSWS_FT_FI3
Number of Residues80
DetailsTOPO_DOM: Extracellular
ChainResidueDetails
AGLU42-VAL48
HTYR65-THR69
GGLU42-VAL48
GTYR65-THR69
CGLU42-VAL48
CTYR65-THR69
EGLU42-VAL48
ETYR65-THR69
ATYR65-THR69
BGLU42-VAL48
BTYR65-THR69
DGLU42-VAL48
DTYR65-THR69
FGLU42-VAL48
FTYR65-THR69
HGLU42-VAL48

site_idSWS_FT_FI4
Number of Residues72
DetailsINTRAMEM: Helical; Pore-forming => ECO:0000255
ChainResidueDetails
ASER49-ALA58
BSER49-ALA58
DSER49-ALA58
FSER49-ALA58
HSER49-ALA58
GSER49-ALA58
CSER49-ALA58
ESER49-ALA58

site_idSWS_FT_FI5
Number of Residues40
DetailsINTRAMEM: Pore-forming => ECO:0000255
ChainResidueDetails
ATHR59-ASP64
BTHR59-ASP64
DTHR59-ASP64
FTHR59-ASP64
HTHR59-ASP64
GTHR59-ASP64
CTHR59-ASP64
ETHR59-ASP64

site_idSWS_FT_FI6
Number of Residues200
DetailsTRANSMEM: Helical; Name=Inner helix M2
ChainResidueDetails
APRO70-LEU95
BPRO70-LEU95
DPRO70-LEU95
FPRO70-LEU95
HPRO70-LEU95
GPRO70-LEU95
CPRO70-LEU95
EPRO70-LEU95

site_idSWS_FT_FI7
Number of Residues24
DetailsBINDING:
ChainResidueDetails
AASP184
FASP184
FGLU210
FGLU212
HASP184
HGLU210
HGLU212
GASP184
GGLU210
GGLU212
CASP184
AGLU210
CGLU210
CGLU212
EASP184
EGLU210
EGLU212
AGLU212
BASP184
BGLU210
BGLU212
DASP184
DGLU210
DGLU212

226707

PDB entries from 2024-10-30

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