8DH9

Leptin-bound leptin receptor complex-D3-D7

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0004896	molecular_function	cytokine receptor activity
A	0006355	biological_process	regulation of DNA-templated transcription
A	0016020	cellular_component	membrane
B	0003700	molecular_function	DNA-binding transcription factor activity
B	0004896	molecular_function	cytokine receptor activity
B	0006355	biological_process	regulation of DNA-templated transcription
B	0016020	cellular_component	membrane
C	0005179	molecular_function	hormone activity
C	0005576	cellular_component	extracellular region
C	0007165	biological_process	signal transduction
D	0005179	molecular_function	hormone activity
D	0005576	cellular_component	extracellular region
D	0007165	biological_process	signal transduction

Functional Information from PROSITE/UniProt

site_id	PS01353
Number of Residues	57
Details	HEMATOPO_REC_L_F2 Long hematopoietin receptor, gp130 family signature. NslgaSlvnfnltfswpmskvsaveslsayplssscvi...LsWtlsPddysll...YlvIeW

Chain	Residue	Details
A	ASN716-TRP772

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	190
Details	Domain: {"description":"Fibronectin type-III 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00316","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	184
Details	Domain: {"description":"Fibronectin type-III 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00316","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	34
Details	Region: {"description":"Leptin-binding","evidences":[{"source":"UniProtKB","id":"P48357","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	8
Details	Motif: {"description":"WSXWS motif"}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	20
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI6
Number of Residues	98
Details	Domain: {"description":"Ig-like"}

Chain

Residue

Details

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