Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

8DCK

Structure of hemolysin A secretion system HlyB/D complex, ATP-bound

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005524	molecular_function	ATP binding
A	0005886	cellular_component	plasma membrane
A	0006508	biological_process	proteolysis
A	0008233	molecular_function	peptidase activity
A	0015421	molecular_function	ABC-type oligopeptide transporter activity
A	0016020	cellular_component	membrane
A	0016787	molecular_function	hydrolase activity
A	0016887	molecular_function	ATP hydrolysis activity
A	0030253	biological_process	protein secretion by the type I secretion system
A	0030256	cellular_component	type I protein secretion system complex
A	0035672	biological_process	oligopeptide transmembrane transport
A	0055085	biological_process	transmembrane transport
A	0140359	molecular_function	ABC-type transporter activity
B	0000166	molecular_function	nucleotide binding
B	0005524	molecular_function	ATP binding
B	0005886	cellular_component	plasma membrane
B	0006508	biological_process	proteolysis
B	0008233	molecular_function	peptidase activity
B	0015421	molecular_function	ABC-type oligopeptide transporter activity
B	0016020	cellular_component	membrane
B	0016787	molecular_function	hydrolase activity
B	0016887	molecular_function	ATP hydrolysis activity
B	0030253	biological_process	protein secretion by the type I secretion system
B	0030256	cellular_component	type I protein secretion system complex
B	0035672	biological_process	oligopeptide transmembrane transport
B	0055085	biological_process	transmembrane transport
B	0140359	molecular_function	ABC-type transporter activity
C	0005886	cellular_component	plasma membrane
C	0009306	biological_process	protein secretion
C	0015031	biological_process	protein transport
C	0016020	cellular_component	membrane
D	0005886	cellular_component	plasma membrane
D	0009306	biological_process	protein secretion
D	0015031	biological_process	protein transport
D	0016020	cellular_component	membrane
E	0000166	molecular_function	nucleotide binding
E	0005524	molecular_function	ATP binding
E	0005886	cellular_component	plasma membrane
E	0006508	biological_process	proteolysis
E	0008233	molecular_function	peptidase activity
E	0015421	molecular_function	ABC-type oligopeptide transporter activity
E	0016020	cellular_component	membrane
E	0016787	molecular_function	hydrolase activity
E	0016887	molecular_function	ATP hydrolysis activity
E	0030253	biological_process	protein secretion by the type I secretion system
E	0030256	cellular_component	type I protein secretion system complex
E	0035672	biological_process	oligopeptide transmembrane transport
E	0055085	biological_process	transmembrane transport
E	0140359	molecular_function	ABC-type transporter activity
F	0000166	molecular_function	nucleotide binding
F	0005524	molecular_function	ATP binding
F	0005886	cellular_component	plasma membrane
F	0006508	biological_process	proteolysis
F	0008233	molecular_function	peptidase activity
F	0015421	molecular_function	ABC-type oligopeptide transporter activity
F	0016020	cellular_component	membrane
F	0016787	molecular_function	hydrolase activity
F	0016887	molecular_function	ATP hydrolysis activity
F	0030253	biological_process	protein secretion by the type I secretion system
F	0030256	cellular_component	type I protein secretion system complex
F	0035672	biological_process	oligopeptide transmembrane transport
F	0055085	biological_process	transmembrane transport
F	0140359	molecular_function	ABC-type transporter activity
G	0005886	cellular_component	plasma membrane
G	0009306	biological_process	protein secretion
G	0015031	biological_process	protein transport
G	0016020	cellular_component	membrane
H	0005886	cellular_component	plasma membrane
H	0009306	biological_process	protein secretion
H	0015031	biological_process	protein transport
H	0016020	cellular_component	membrane
I	0000166	molecular_function	nucleotide binding
I	0005524	molecular_function	ATP binding
I	0005886	cellular_component	plasma membrane
I	0006508	biological_process	proteolysis
I	0008233	molecular_function	peptidase activity
I	0015421	molecular_function	ABC-type oligopeptide transporter activity
I	0016020	cellular_component	membrane
I	0016787	molecular_function	hydrolase activity
I	0016887	molecular_function	ATP hydrolysis activity
I	0030253	biological_process	protein secretion by the type I secretion system
I	0030256	cellular_component	type I protein secretion system complex
I	0035672	biological_process	oligopeptide transmembrane transport
I	0055085	biological_process	transmembrane transport
I	0140359	molecular_function	ABC-type transporter activity
J	0000166	molecular_function	nucleotide binding
J	0005524	molecular_function	ATP binding
J	0005886	cellular_component	plasma membrane
J	0006508	biological_process	proteolysis
J	0008233	molecular_function	peptidase activity
J	0015421	molecular_function	ABC-type oligopeptide transporter activity
J	0016020	cellular_component	membrane
J	0016787	molecular_function	hydrolase activity
J	0016887	molecular_function	ATP hydrolysis activity
J	0030253	biological_process	protein secretion by the type I secretion system
J	0030256	cellular_component	type I protein secretion system complex
J	0035672	biological_process	oligopeptide transmembrane transport
J	0055085	biological_process	transmembrane transport
J	0140359	molecular_function	ABC-type transporter activity
K	0005886	cellular_component	plasma membrane
K	0009306	biological_process	protein secretion
K	0015031	biological_process	protein transport
K	0016020	cellular_component	membrane
L	0005886	cellular_component	plasma membrane
L	0009306	biological_process	protein secretion
L	0015031	biological_process	protein transport
L	0016020	cellular_component	membrane

Functional Information from PROSITE/UniProt

site_id	PS00211
Number of Residues	15
Details	ABC_TRANSPORTER_1 ABC transporters family signature. LSGGQRQRIAIARAL

Chain	Residue	Details
A	LEU606-LEU620

site_id	PS00543
Number of Residues	23
Details	HLYD_FAMILY HlyD family secretion proteins signature. LssGMavtAeIkTGmRsVIsYLL

Chain	Residue	Details
C	LEU442-LEU464

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	600
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"PROSITE-ProRule","id":"PRU00441","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	1692
Details	Domain: {"description":"ABC transmembrane type-1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00441","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	3
Details	Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00362","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	42
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00362","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU00434","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	705
Details	Domain: {"description":"ABC transporter","evidences":[{"source":"PROSITE-ProRule","id":"PRU00362","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU00434","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)