8DAO

Crystal structure of SARS-CoV-2 spike stem fusion peptide in complex with neutralizing antibody COV44-79

Functional Information from GO Data

Chain	GOid	namespace	contents
F	0002250	biological_process	adaptive immune response
F	0003823	molecular_function	antigen binding
F	0005576	cellular_component	extracellular region
F	0005615	cellular_component	extracellular space
F	0005886	cellular_component	plasma membrane
F	0006955	biological_process	immune response
F	0016064	biological_process	immunoglobulin mediated immune response
F	0019814	cellular_component	immunoglobulin complex
F	0050853	biological_process	B cell receptor signaling pathway
F	0070062	cellular_component	extracellular exosome
F	0071735	cellular_component	IgG immunoglobulin complex
F	0071738	cellular_component	IgD immunoglobulin complex
F	0071742	cellular_component	IgE immunoglobulin complex
F	0071745	cellular_component	IgA immunoglobulin complex
F	0071753	cellular_component	IgM immunoglobulin complex
F	0072562	cellular_component	blood microparticle
H	0002250	biological_process	adaptive immune response
H	0003823	molecular_function	antigen binding
H	0005576	cellular_component	extracellular region
H	0005615	cellular_component	extracellular space
H	0005886	cellular_component	plasma membrane
H	0006955	biological_process	immune response
H	0016064	biological_process	immunoglobulin mediated immune response
H	0019814	cellular_component	immunoglobulin complex
H	0050853	biological_process	B cell receptor signaling pathway
H	0070062	cellular_component	extracellular exosome
H	0071735	cellular_component	IgG immunoglobulin complex
H	0071738	cellular_component	IgD immunoglobulin complex
H	0071742	cellular_component	IgE immunoglobulin complex
H	0071745	cellular_component	IgA immunoglobulin complex
H	0071753	cellular_component	IgM immunoglobulin complex
H	0072562	cellular_component	blood microparticle

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH

Chain	Residue	Details
F	TYR192-HIS198
E	TYR194-HIS200

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	SITE: Cleavage; by host TMPRSS2 or CTSL => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32703818, ECO:0000269|PubMed:34159616

Chain	Residue	Details
I	ARG815
J	ARG815

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