8D9V

gamma-Arf1 homodimeric interface within AP-1, Arf1, Nef lattice on narrow membrane tubes

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000139	cellular_component	Golgi membrane
A	0005515	molecular_function	protein binding
A	0005765	cellular_component	lysosomal membrane
A	0005769	cellular_component	early endosome
A	0005794	cellular_component	Golgi apparatus
A	0005829	cellular_component	cytosol
A	0006886	biological_process	intracellular protein transport
A	0008021	cellular_component	synaptic vesicle
A	0012505	cellular_component	endomembrane system
A	0015031	biological_process	protein transport
A	0016192	biological_process	vesicle-mediated transport
A	0019901	molecular_function	protein kinase binding
A	0030117	cellular_component	membrane coat
A	0030121	cellular_component	AP-1 adaptor complex
A	0030131	cellular_component	clathrin adaptor complex
A	0030276	molecular_function	clathrin binding
A	0030659	cellular_component	cytoplasmic vesicle membrane
A	0030665	cellular_component	clathrin-coated vesicle membrane
A	0031410	cellular_component	cytoplasmic vesicle
A	0032588	cellular_component	trans-Golgi network membrane
A	0060155	biological_process	platelet dense granule organization
A	0110010	biological_process	basolateral protein secretion
A	1903232	biological_process	melanosome assembly
B	0000139	cellular_component	Golgi membrane
B	0005515	molecular_function	protein binding
B	0005765	cellular_component	lysosomal membrane
B	0005769	cellular_component	early endosome
B	0005794	cellular_component	Golgi apparatus
B	0005829	cellular_component	cytosol
B	0006886	biological_process	intracellular protein transport
B	0008021	cellular_component	synaptic vesicle
B	0012505	cellular_component	endomembrane system
B	0015031	biological_process	protein transport
B	0016192	biological_process	vesicle-mediated transport
B	0019901	molecular_function	protein kinase binding
B	0030117	cellular_component	membrane coat
B	0030121	cellular_component	AP-1 adaptor complex
B	0030131	cellular_component	clathrin adaptor complex
B	0030276	molecular_function	clathrin binding
B	0030659	cellular_component	cytoplasmic vesicle membrane
B	0030665	cellular_component	clathrin-coated vesicle membrane
B	0031410	cellular_component	cytoplasmic vesicle
B	0032588	cellular_component	trans-Golgi network membrane
B	0060155	biological_process	platelet dense granule organization
B	0110010	biological_process	basolateral protein secretion
B	1903232	biological_process	melanosome assembly
C	0000166	molecular_function	nucleotide binding
C	0000287	molecular_function	magnesium ion binding
C	0003924	molecular_function	GTPase activity
C	0005525	molecular_function	GTP binding
C	0005794	cellular_component	Golgi apparatus
C	0005829	cellular_component	cytosol
C	0006878	biological_process	intracellular copper ion homeostasis
C	0012505	cellular_component	endomembrane system
C	0015031	biological_process	protein transport
C	0016192	biological_process	vesicle-mediated transport
C	0019904	molecular_function	protein domain specific binding
C	0030017	cellular_component	sarcomere
C	0031252	cellular_component	cell leading edge
C	0032991	cellular_component	protein-containing complex
C	0046872	molecular_function	metal ion binding
C	0098586	biological_process	cellular response to virus
C	1990386	biological_process	mitotic cleavage furrow ingression
D	0000166	molecular_function	nucleotide binding
D	0000287	molecular_function	magnesium ion binding
D	0003924	molecular_function	GTPase activity
D	0005525	molecular_function	GTP binding
D	0005794	cellular_component	Golgi apparatus
D	0005829	cellular_component	cytosol
D	0006878	biological_process	intracellular copper ion homeostasis
D	0012505	cellular_component	endomembrane system
D	0015031	biological_process	protein transport
D	0016192	biological_process	vesicle-mediated transport
D	0019904	molecular_function	protein domain specific binding
D	0030017	cellular_component	sarcomere
D	0031252	cellular_component	cell leading edge
D	0032991	cellular_component	protein-containing complex
D	0046872	molecular_function	metal ion binding
D	0098586	biological_process	cellular response to virus
D	1990386	biological_process	mitotic cleavage furrow ingression
E	0006886	biological_process	intracellular protein transport
E	0016192	biological_process	vesicle-mediated transport
E	0030117	cellular_component	membrane coat
F	0000166	molecular_function	nucleotide binding
F	0000287	molecular_function	magnesium ion binding
F	0003924	molecular_function	GTPase activity
F	0005525	molecular_function	GTP binding
F	0005794	cellular_component	Golgi apparatus
F	0005829	cellular_component	cytosol
F	0006878	biological_process	intracellular copper ion homeostasis
F	0012505	cellular_component	endomembrane system
F	0015031	biological_process	protein transport
F	0016192	biological_process	vesicle-mediated transport
F	0019904	molecular_function	protein domain specific binding
F	0030017	cellular_component	sarcomere
F	0031252	cellular_component	cell leading edge
F	0032991	cellular_component	protein-containing complex
F	0046872	molecular_function	metal ion binding
F	0098586	biological_process	cellular response to virus
F	1990386	biological_process	mitotic cleavage furrow ingression
G	0006886	biological_process	intracellular protein transport
G	0016192	biological_process	vesicle-mediated transport
G	0030117	cellular_component	membrane coat
H	0000166	molecular_function	nucleotide binding
H	0000287	molecular_function	magnesium ion binding
H	0003924	molecular_function	GTPase activity
H	0005525	molecular_function	GTP binding
H	0005794	cellular_component	Golgi apparatus
H	0005829	cellular_component	cytosol
H	0006878	biological_process	intracellular copper ion homeostasis
H	0012505	cellular_component	endomembrane system
H	0015031	biological_process	protein transport
H	0016192	biological_process	vesicle-mediated transport
H	0019904	molecular_function	protein domain specific binding
H	0030017	cellular_component	sarcomere
H	0031252	cellular_component	cell leading edge
H	0032991	cellular_component	protein-containing complex
H	0046872	molecular_function	metal ion binding
H	0098586	biological_process	cellular response to virus
H	1990386	biological_process	mitotic cleavage furrow ingression
I	0005102	molecular_function	signaling receptor binding
I	0005515	molecular_function	protein binding
I	0005525	molecular_function	GTP binding
I	0005576	cellular_component	extracellular region
I	0010561	biological_process	negative regulation of glycoprotein biosynthetic process
I	0016020	cellular_component	membrane
I	0017124	molecular_function	SH3 domain binding
I	0019058	biological_process	viral life cycle
I	0019901	molecular_function	protein kinase binding
I	0020002	cellular_component	host cell plasma membrane
I	0031996	molecular_function	thioesterase binding
I	0033668	biological_process	symbiont-mediated suppression of host apoptosis
I	0039504	biological_process	symbiont-mediated suppression of host adaptive immune response
I	0039505	biological_process	symbiont-mediated suppression of host antigen processing and presentation of peptide antigen via MHC class II
I	0042288	molecular_function	MHC class I protein binding
I	0042609	molecular_function	CD4 receptor binding
I	0044178	cellular_component	host cell Golgi membrane
I	0044423	cellular_component	virion component
I	0046776	biological_process	symbiont-mediated suppression of host antigen processing and presentation of peptide antigen via MHC class I
I	0050848	biological_process	regulation of calcium-mediated signaling
I	0051117	molecular_function	ATPase binding
I	0051246	biological_process	regulation of protein metabolic process
I	0051701	biological_process	biological process involved in interaction with host
I	0052031	biological_process	symbiont-mediated perturbation of host defense response
I	0052170	biological_process	symbiont-mediated suppression of host innate immune response
I	0070206	biological_process	protein trimerization
I	0140321	biological_process	symbiont-mediated suppression of host autophagy
J	0005515	molecular_function	protein binding
J	0005765	cellular_component	lysosomal membrane
J	0005769	cellular_component	early endosome
J	0005794	cellular_component	Golgi apparatus
J	0005802	cellular_component	trans-Golgi network
J	0005829	cellular_component	cytosol
J	0006886	biological_process	intracellular protein transport
J	0006896	biological_process	Golgi to vacuole transport
J	0015031	biological_process	protein transport
J	0016192	biological_process	vesicle-mediated transport
J	0030121	cellular_component	AP-1 adaptor complex
J	0030131	cellular_component	clathrin adaptor complex
J	0030665	cellular_component	clathrin-coated vesicle membrane
J	0031410	cellular_component	cytoplasmic vesicle
J	0032438	biological_process	melanosome organization
J	0032588	cellular_component	trans-Golgi network membrane
J	0035615	molecular_function	clathrin adaptor activity
J	0035646	biological_process	endosome to melanosome transport
J	0045202	cellular_component	synapse
J	0060155	biological_process	platelet dense granule organization
J	1903232	biological_process	melanosome assembly
K	0005102	molecular_function	signaling receptor binding
K	0005515	molecular_function	protein binding
K	0005525	molecular_function	GTP binding
K	0005576	cellular_component	extracellular region
K	0010561	biological_process	negative regulation of glycoprotein biosynthetic process
K	0016020	cellular_component	membrane
K	0017124	molecular_function	SH3 domain binding
K	0019058	biological_process	viral life cycle
K	0019901	molecular_function	protein kinase binding
K	0020002	cellular_component	host cell plasma membrane
K	0031996	molecular_function	thioesterase binding
K	0033668	biological_process	symbiont-mediated suppression of host apoptosis
K	0039504	biological_process	symbiont-mediated suppression of host adaptive immune response
K	0039505	biological_process	symbiont-mediated suppression of host antigen processing and presentation of peptide antigen via MHC class II
K	0042288	molecular_function	MHC class I protein binding
K	0042609	molecular_function	CD4 receptor binding
K	0044178	cellular_component	host cell Golgi membrane
K	0044423	cellular_component	virion component
K	0046776	biological_process	symbiont-mediated suppression of host antigen processing and presentation of peptide antigen via MHC class I
K	0050848	biological_process	regulation of calcium-mediated signaling
K	0051117	molecular_function	ATPase binding
K	0051246	biological_process	regulation of protein metabolic process
K	0051701	biological_process	biological process involved in interaction with host
K	0052031	biological_process	symbiont-mediated perturbation of host defense response
K	0052170	biological_process	symbiont-mediated suppression of host innate immune response
K	0070206	biological_process	protein trimerization
K	0140321	biological_process	symbiont-mediated suppression of host autophagy
L	0005102	molecular_function	signaling receptor binding
L	0005515	molecular_function	protein binding
L	0005525	molecular_function	GTP binding
L	0005576	cellular_component	extracellular region
L	0010561	biological_process	negative regulation of glycoprotein biosynthetic process
L	0016020	cellular_component	membrane
L	0017124	molecular_function	SH3 domain binding
L	0019058	biological_process	viral life cycle
L	0019901	molecular_function	protein kinase binding
L	0020002	cellular_component	host cell plasma membrane
L	0031996	molecular_function	thioesterase binding
L	0033668	biological_process	symbiont-mediated suppression of host apoptosis
L	0039504	biological_process	symbiont-mediated suppression of host adaptive immune response
L	0039505	biological_process	symbiont-mediated suppression of host antigen processing and presentation of peptide antigen via MHC class II
L	0042288	molecular_function	MHC class I protein binding
L	0042609	molecular_function	CD4 receptor binding
L	0044178	cellular_component	host cell Golgi membrane
L	0044423	cellular_component	virion component
L	0046776	biological_process	symbiont-mediated suppression of host antigen processing and presentation of peptide antigen via MHC class I
L	0050848	biological_process	regulation of calcium-mediated signaling
L	0051117	molecular_function	ATPase binding
L	0051246	biological_process	regulation of protein metabolic process
L	0051701	biological_process	biological process involved in interaction with host
L	0052031	biological_process	symbiont-mediated perturbation of host defense response
L	0052170	biological_process	symbiont-mediated suppression of host innate immune response
L	0070206	biological_process	protein trimerization
L	0140321	biological_process	symbiont-mediated suppression of host autophagy
M	0005515	molecular_function	protein binding
M	0005765	cellular_component	lysosomal membrane
M	0005769	cellular_component	early endosome
M	0005794	cellular_component	Golgi apparatus
M	0005802	cellular_component	trans-Golgi network
M	0005829	cellular_component	cytosol
M	0006886	biological_process	intracellular protein transport
M	0006896	biological_process	Golgi to vacuole transport
M	0015031	biological_process	protein transport
M	0016192	biological_process	vesicle-mediated transport
M	0030121	cellular_component	AP-1 adaptor complex
M	0030131	cellular_component	clathrin adaptor complex
M	0030665	cellular_component	clathrin-coated vesicle membrane
M	0031410	cellular_component	cytoplasmic vesicle
M	0032438	biological_process	melanosome organization
M	0032588	cellular_component	trans-Golgi network membrane
M	0035615	molecular_function	clathrin adaptor activity
M	0035646	biological_process	endosome to melanosome transport
M	0045202	cellular_component	synapse
M	0060155	biological_process	platelet dense granule organization
M	1903232	biological_process	melanosome assembly
N	0005102	molecular_function	signaling receptor binding
N	0005515	molecular_function	protein binding
N	0005525	molecular_function	GTP binding
N	0005576	cellular_component	extracellular region
N	0010561	biological_process	negative regulation of glycoprotein biosynthetic process
N	0016020	cellular_component	membrane
N	0017124	molecular_function	SH3 domain binding
N	0019058	biological_process	viral life cycle
N	0019901	molecular_function	protein kinase binding
N	0020002	cellular_component	host cell plasma membrane
N	0031996	molecular_function	thioesterase binding
N	0033668	biological_process	symbiont-mediated suppression of host apoptosis
N	0039504	biological_process	symbiont-mediated suppression of host adaptive immune response
N	0039505	biological_process	symbiont-mediated suppression of host antigen processing and presentation of peptide antigen via MHC class II
N	0042288	molecular_function	MHC class I protein binding
N	0042609	molecular_function	CD4 receptor binding
N	0044178	cellular_component	host cell Golgi membrane
N	0044423	cellular_component	virion component
N	0046776	biological_process	symbiont-mediated suppression of host antigen processing and presentation of peptide antigen via MHC class I
N	0050848	biological_process	regulation of calcium-mediated signaling
N	0051117	molecular_function	ATPase binding
N	0051246	biological_process	regulation of protein metabolic process
N	0051701	biological_process	biological process involved in interaction with host
N	0052031	biological_process	symbiont-mediated perturbation of host defense response
N	0052170	biological_process	symbiont-mediated suppression of host innate immune response
N	0070206	biological_process	protein trimerization
N	0140321	biological_process	symbiont-mediated suppression of host autophagy
O	0000139	cellular_component	Golgi membrane
O	0005515	molecular_function	protein binding
O	0005765	cellular_component	lysosomal membrane
O	0005769	cellular_component	early endosome
O	0005794	cellular_component	Golgi apparatus
O	0005829	cellular_component	cytosol
O	0005905	cellular_component	clathrin-coated pit
O	0006605	biological_process	protein targeting
O	0006886	biological_process	intracellular protein transport
O	0015031	biological_process	protein transport
O	0016192	biological_process	vesicle-mediated transport
O	0030117	cellular_component	membrane coat
O	0030121	cellular_component	AP-1 adaptor complex
O	0030659	cellular_component	cytoplasmic vesicle membrane
O	0031410	cellular_component	cytoplasmic vesicle
O	0032588	cellular_component	trans-Golgi network membrane
O	0035615	molecular_function	clathrin adaptor activity
O	0060155	biological_process	platelet dense granule organization
O	1903232	biological_process	melanosome assembly
P	0006955	biological_process	immune response
P	0019882	biological_process	antigen processing and presentation
S	0000139	cellular_component	Golgi membrane
S	0005515	molecular_function	protein binding
S	0005765	cellular_component	lysosomal membrane
S	0005769	cellular_component	early endosome
S	0005794	cellular_component	Golgi apparatus
S	0005829	cellular_component	cytosol
S	0005905	cellular_component	clathrin-coated pit
S	0006605	biological_process	protein targeting
S	0006886	biological_process	intracellular protein transport
S	0015031	biological_process	protein transport
S	0016192	biological_process	vesicle-mediated transport
S	0030117	cellular_component	membrane coat
S	0030121	cellular_component	AP-1 adaptor complex
S	0030659	cellular_component	cytoplasmic vesicle membrane
S	0031410	cellular_component	cytoplasmic vesicle
S	0032588	cellular_component	trans-Golgi network membrane
S	0035615	molecular_function	clathrin adaptor activity
S	0060155	biological_process	platelet dense granule organization
S	1903232	biological_process	melanosome assembly
Y	0006955	biological_process	immune response
Y	0019882	biological_process	antigen processing and presentation

Functional Information from PROSITE/UniProt

site_id	PS00989
Number of Residues	11
Details	CLAT_ADAPTOR_S Clathrin adaptor complexes small chain signature. LVYKryasLYF

Chain	Residue	Details
S	LEU57-PHE67

---

site_id	PS00990
Number of Residues	21
Details	CLAT_ADAPTOR_M_1 Clathrin adaptor complexes medium chain signature 1. VSWRse.GikYrkNeVFLDVIE

Chain	Residue	Details
M	VAL157-GLU177

---

site_id	PS00991
Number of Residues	15
Details	CLAT_ADAPTOR_M_2 Clathrin adaptor complexes medium chain signature 2. IsFIPPdGeFeLmsY

Chain	Residue	Details
M	ILE253-TYR267

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI7
Number of Residues	8
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	2
Details	Modified residue: {"description":"3'-nitrotyrosine","evidences":[{"source":"UniProtKB","id":"O35643","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	506
Details	Domain: {"description":"MHD","evidences":[{"source":"PROSITE-ProRule","id":"PRU00404","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	2
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"UniProtKB","id":"Q9BXS5","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	4
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"17242355","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21183079","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	2
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"Q32Q06","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---