8D86

Isoreticular, interpenetrating co-crystal of Replication Initiator Protein REPE54 and symmetrical expanded duplex (31mer) containing the cognate REPE54 sequence and an additional G-C rich sequence co-crystallized with a guest small molecule, netropsin.

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0003677	molecular_function	DNA binding
C	0003887	molecular_function	DNA-directed DNA polymerase activity
C	0006260	biological_process	DNA replication
C	0006270	biological_process	DNA replication initiation
C	0006276	biological_process	plasmid maintenance
C	0071897	biological_process	DNA biosynthetic process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	15
Details	DNA_BIND: H-T-H motif

Chain	Residue	Details
C	SER75-ARG83
C	ARG200-ARG207

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