8CVA
Structure of Hyoscyamine 6-beta Hydroxylase in complex with iron, succinate, and 6-OH-hyoscyamine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0002238 | biological_process | response to molecule of fungal origin |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0006103 | biological_process | 2-oxoglutarate metabolic process |
| A | 0006105 | biological_process | succinate metabolic process |
| A | 0009805 | biological_process | coumarin biosynthetic process |
| A | 0016706 | molecular_function | 2-oxoglutarate-dependent dioxygenase activity |
| A | 0047594 | molecular_function | 6-beta-hydroxyhyoscyamine epoxidase activity |
| A | 0047998 | molecular_function | hyoscyamine (6S)-dioxygenase activity |
| A | 1900991 | biological_process | scopolamine biosynthetic process |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"39172701","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"8CV8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8CV9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8CVB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8CVC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8CVD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8CVF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8CVG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8CVH","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"39172701","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"8CV8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8CV9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8CVA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8CVB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8CVC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8CVD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8CVE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8CVF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8CVG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8CVH","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"39172701","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8CV8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8CVB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8CVE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8CVG","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"39172701","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8CV9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8CVA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8CVC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8CVD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8CVF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8CVH","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"39172701","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8CV9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8CVA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8CVC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8CVD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8CVF","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00805","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"39172701","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8CV8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8CVA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8CVB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8CVD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8CVE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8CVG","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
