8CU8

Cryo-EM structure of Ferritin 2 from Caenorhabditis elegans, FTN-2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004322	molecular_function	ferroxidase activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0006826	biological_process	iron ion transport
A	0006879	biological_process	intracellular iron ion homeostasis
A	0008198	molecular_function	ferrous iron binding
A	0008199	molecular_function	ferric iron binding
A	0016491	molecular_function	oxidoreductase activity
A	0042802	molecular_function	identical protein binding
A	0046872	molecular_function	metal ion binding
A	0050830	biological_process	defense response to Gram-positive bacterium
C	0004322	molecular_function	ferroxidase activity
C	0005515	molecular_function	protein binding
C	0005737	cellular_component	cytoplasm
C	0006826	biological_process	iron ion transport
C	0006879	biological_process	intracellular iron ion homeostasis
C	0008198	molecular_function	ferrous iron binding
C	0008199	molecular_function	ferric iron binding
C	0016491	molecular_function	oxidoreductase activity
C	0042802	molecular_function	identical protein binding
C	0046872	molecular_function	metal ion binding
C	0050830	biological_process	defense response to Gram-positive bacterium
D	0004322	molecular_function	ferroxidase activity
D	0005515	molecular_function	protein binding
D	0005737	cellular_component	cytoplasm
D	0006826	biological_process	iron ion transport
D	0006879	biological_process	intracellular iron ion homeostasis
D	0008198	molecular_function	ferrous iron binding
D	0008199	molecular_function	ferric iron binding
D	0016491	molecular_function	oxidoreductase activity
D	0042802	molecular_function	identical protein binding
D	0046872	molecular_function	metal ion binding
D	0050830	biological_process	defense response to Gram-positive bacterium
E	0004322	molecular_function	ferroxidase activity
E	0005515	molecular_function	protein binding
E	0005737	cellular_component	cytoplasm
E	0006826	biological_process	iron ion transport
E	0006879	biological_process	intracellular iron ion homeostasis
E	0008198	molecular_function	ferrous iron binding
E	0008199	molecular_function	ferric iron binding
E	0016491	molecular_function	oxidoreductase activity
E	0042802	molecular_function	identical protein binding
E	0046872	molecular_function	metal ion binding
E	0050830	biological_process	defense response to Gram-positive bacterium
F	0004322	molecular_function	ferroxidase activity
F	0005515	molecular_function	protein binding
F	0005737	cellular_component	cytoplasm
F	0006826	biological_process	iron ion transport
F	0006879	biological_process	intracellular iron ion homeostasis
F	0008198	molecular_function	ferrous iron binding
F	0008199	molecular_function	ferric iron binding
F	0016491	molecular_function	oxidoreductase activity
F	0042802	molecular_function	identical protein binding
F	0046872	molecular_function	metal ion binding
F	0050830	biological_process	defense response to Gram-positive bacterium
G	0004322	molecular_function	ferroxidase activity
G	0005515	molecular_function	protein binding
G	0005737	cellular_component	cytoplasm
G	0006826	biological_process	iron ion transport
G	0006879	biological_process	intracellular iron ion homeostasis
G	0008198	molecular_function	ferrous iron binding
G	0008199	molecular_function	ferric iron binding
G	0016491	molecular_function	oxidoreductase activity
G	0042802	molecular_function	identical protein binding
G	0046872	molecular_function	metal ion binding
G	0050830	biological_process	defense response to Gram-positive bacterium
H	0004322	molecular_function	ferroxidase activity
H	0005515	molecular_function	protein binding
H	0005737	cellular_component	cytoplasm
H	0006826	biological_process	iron ion transport
H	0006879	biological_process	intracellular iron ion homeostasis
H	0008198	molecular_function	ferrous iron binding
H	0008199	molecular_function	ferric iron binding
H	0016491	molecular_function	oxidoreductase activity
H	0042802	molecular_function	identical protein binding
H	0046872	molecular_function	metal ion binding
H	0050830	biological_process	defense response to Gram-positive bacterium
I	0004322	molecular_function	ferroxidase activity
I	0005515	molecular_function	protein binding
I	0005737	cellular_component	cytoplasm
I	0006826	biological_process	iron ion transport
I	0006879	biological_process	intracellular iron ion homeostasis
I	0008198	molecular_function	ferrous iron binding
I	0008199	molecular_function	ferric iron binding
I	0016491	molecular_function	oxidoreductase activity
I	0042802	molecular_function	identical protein binding
I	0046872	molecular_function	metal ion binding
I	0050830	biological_process	defense response to Gram-positive bacterium
J	0004322	molecular_function	ferroxidase activity
J	0005515	molecular_function	protein binding
J	0005737	cellular_component	cytoplasm
J	0006826	biological_process	iron ion transport
J	0006879	biological_process	intracellular iron ion homeostasis
J	0008198	molecular_function	ferrous iron binding
J	0008199	molecular_function	ferric iron binding
J	0016491	molecular_function	oxidoreductase activity
J	0042802	molecular_function	identical protein binding
J	0046872	molecular_function	metal ion binding
J	0050830	biological_process	defense response to Gram-positive bacterium
K	0004322	molecular_function	ferroxidase activity
K	0005515	molecular_function	protein binding
K	0005737	cellular_component	cytoplasm
K	0006826	biological_process	iron ion transport
K	0006879	biological_process	intracellular iron ion homeostasis
K	0008198	molecular_function	ferrous iron binding
K	0008199	molecular_function	ferric iron binding
K	0016491	molecular_function	oxidoreductase activity
K	0042802	molecular_function	identical protein binding
K	0046872	molecular_function	metal ion binding
K	0050830	biological_process	defense response to Gram-positive bacterium
L	0004322	molecular_function	ferroxidase activity
L	0005515	molecular_function	protein binding
L	0005737	cellular_component	cytoplasm
L	0006826	biological_process	iron ion transport
L	0006879	biological_process	intracellular iron ion homeostasis
L	0008198	molecular_function	ferrous iron binding
L	0008199	molecular_function	ferric iron binding
L	0016491	molecular_function	oxidoreductase activity
L	0042802	molecular_function	identical protein binding
L	0046872	molecular_function	metal ion binding
L	0050830	biological_process	defense response to Gram-positive bacterium
M	0004322	molecular_function	ferroxidase activity
M	0005515	molecular_function	protein binding
M	0005737	cellular_component	cytoplasm
M	0006826	biological_process	iron ion transport
M	0006879	biological_process	intracellular iron ion homeostasis
M	0008198	molecular_function	ferrous iron binding
M	0008199	molecular_function	ferric iron binding
M	0016491	molecular_function	oxidoreductase activity
M	0042802	molecular_function	identical protein binding
M	0046872	molecular_function	metal ion binding
M	0050830	biological_process	defense response to Gram-positive bacterium
N	0004322	molecular_function	ferroxidase activity
N	0005515	molecular_function	protein binding
N	0005737	cellular_component	cytoplasm
N	0006826	biological_process	iron ion transport
N	0006879	biological_process	intracellular iron ion homeostasis
N	0008198	molecular_function	ferrous iron binding
N	0008199	molecular_function	ferric iron binding
N	0016491	molecular_function	oxidoreductase activity
N	0042802	molecular_function	identical protein binding
N	0046872	molecular_function	metal ion binding
N	0050830	biological_process	defense response to Gram-positive bacterium
O	0004322	molecular_function	ferroxidase activity
O	0005515	molecular_function	protein binding
O	0005737	cellular_component	cytoplasm
O	0006826	biological_process	iron ion transport
O	0006879	biological_process	intracellular iron ion homeostasis
O	0008198	molecular_function	ferrous iron binding
O	0008199	molecular_function	ferric iron binding
O	0016491	molecular_function	oxidoreductase activity
O	0042802	molecular_function	identical protein binding
O	0046872	molecular_function	metal ion binding
O	0050830	biological_process	defense response to Gram-positive bacterium
P	0004322	molecular_function	ferroxidase activity
P	0005515	molecular_function	protein binding
P	0005737	cellular_component	cytoplasm
P	0006826	biological_process	iron ion transport
P	0006879	biological_process	intracellular iron ion homeostasis
P	0008198	molecular_function	ferrous iron binding
P	0008199	molecular_function	ferric iron binding
P	0016491	molecular_function	oxidoreductase activity
P	0042802	molecular_function	identical protein binding
P	0046872	molecular_function	metal ion binding
P	0050830	biological_process	defense response to Gram-positive bacterium
Q	0004322	molecular_function	ferroxidase activity
Q	0005515	molecular_function	protein binding
Q	0005737	cellular_component	cytoplasm
Q	0006826	biological_process	iron ion transport
Q	0006879	biological_process	intracellular iron ion homeostasis
Q	0008198	molecular_function	ferrous iron binding
Q	0008199	molecular_function	ferric iron binding
Q	0016491	molecular_function	oxidoreductase activity
Q	0042802	molecular_function	identical protein binding
Q	0046872	molecular_function	metal ion binding
Q	0050830	biological_process	defense response to Gram-positive bacterium
R	0004322	molecular_function	ferroxidase activity
R	0005515	molecular_function	protein binding
R	0005737	cellular_component	cytoplasm
R	0006826	biological_process	iron ion transport
R	0006879	biological_process	intracellular iron ion homeostasis
R	0008198	molecular_function	ferrous iron binding
R	0008199	molecular_function	ferric iron binding
R	0016491	molecular_function	oxidoreductase activity
R	0042802	molecular_function	identical protein binding
R	0046872	molecular_function	metal ion binding
R	0050830	biological_process	defense response to Gram-positive bacterium
S	0004322	molecular_function	ferroxidase activity
S	0005515	molecular_function	protein binding
S	0005737	cellular_component	cytoplasm
S	0006826	biological_process	iron ion transport
S	0006879	biological_process	intracellular iron ion homeostasis
S	0008198	molecular_function	ferrous iron binding
S	0008199	molecular_function	ferric iron binding
S	0016491	molecular_function	oxidoreductase activity
S	0042802	molecular_function	identical protein binding
S	0046872	molecular_function	metal ion binding
S	0050830	biological_process	defense response to Gram-positive bacterium
T	0004322	molecular_function	ferroxidase activity
T	0005515	molecular_function	protein binding
T	0005737	cellular_component	cytoplasm
T	0006826	biological_process	iron ion transport
T	0006879	biological_process	intracellular iron ion homeostasis
T	0008198	molecular_function	ferrous iron binding
T	0008199	molecular_function	ferric iron binding
T	0016491	molecular_function	oxidoreductase activity
T	0042802	molecular_function	identical protein binding
T	0046872	molecular_function	metal ion binding
T	0050830	biological_process	defense response to Gram-positive bacterium
U	0004322	molecular_function	ferroxidase activity
U	0005515	molecular_function	protein binding
U	0005737	cellular_component	cytoplasm
U	0006826	biological_process	iron ion transport
U	0006879	biological_process	intracellular iron ion homeostasis
U	0008198	molecular_function	ferrous iron binding
U	0008199	molecular_function	ferric iron binding
U	0016491	molecular_function	oxidoreductase activity
U	0042802	molecular_function	identical protein binding
U	0046872	molecular_function	metal ion binding
U	0050830	biological_process	defense response to Gram-positive bacterium
V	0004322	molecular_function	ferroxidase activity
V	0005515	molecular_function	protein binding
V	0005737	cellular_component	cytoplasm
V	0006826	biological_process	iron ion transport
V	0006879	biological_process	intracellular iron ion homeostasis
V	0008198	molecular_function	ferrous iron binding
V	0008199	molecular_function	ferric iron binding
V	0016491	molecular_function	oxidoreductase activity
V	0042802	molecular_function	identical protein binding
V	0046872	molecular_function	metal ion binding
V	0050830	biological_process	defense response to Gram-positive bacterium
W	0004322	molecular_function	ferroxidase activity
W	0005515	molecular_function	protein binding
W	0005737	cellular_component	cytoplasm
W	0006826	biological_process	iron ion transport
W	0006879	biological_process	intracellular iron ion homeostasis
W	0008198	molecular_function	ferrous iron binding
W	0008199	molecular_function	ferric iron binding
W	0016491	molecular_function	oxidoreductase activity
W	0042802	molecular_function	identical protein binding
W	0046872	molecular_function	metal ion binding
W	0050830	biological_process	defense response to Gram-positive bacterium
X	0004322	molecular_function	ferroxidase activity
X	0005515	molecular_function	protein binding
X	0005737	cellular_component	cytoplasm
X	0006826	biological_process	iron ion transport
X	0006879	biological_process	intracellular iron ion homeostasis
X	0008198	molecular_function	ferrous iron binding
X	0008199	molecular_function	ferric iron binding
X	0016491	molecular_function	oxidoreductase activity
X	0042802	molecular_function	identical protein binding
X	0046872	molecular_function	metal ion binding
X	0050830	biological_process	defense response to Gram-positive bacterium
Y	0004322	molecular_function	ferroxidase activity
Y	0005515	molecular_function	protein binding
Y	0005737	cellular_component	cytoplasm
Y	0006826	biological_process	iron ion transport
Y	0006879	biological_process	intracellular iron ion homeostasis
Y	0008198	molecular_function	ferrous iron binding
Y	0008199	molecular_function	ferric iron binding
Y	0016491	molecular_function	oxidoreductase activity
Y	0042802	molecular_function	identical protein binding
Y	0046872	molecular_function	metal ion binding
Y	0050830	biological_process	defense response to Gram-positive bacterium

Functional Information from PROSITE/UniProt

site_id	PS00204
Number of Residues	21
Details	FERRITIN_2 Ferritin iron-binding regions signature 2. DahLTDFIEekYLdeqvksIN

Chain	Residue	Details
A	ASP122-ASN142

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