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8CTK

Cryo-EM structure of SARS-CoV-2 M protein in a lipid nanodisc

Functional Information from GO Data
ChainGOidnamespacecontents
A0005515molecular_functionprotein binding
A0005886cellular_componentplasma membrane
A0016020cellular_componentmembrane
A0019031cellular_componentviral envelope
A0030430cellular_componenthost cell cytoplasm
A0033644cellular_componenthost cell membrane
A0039545biological_processsymbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
A0039660molecular_functionstructural constituent of virion
A0042802molecular_functionidentical protein binding
A0044178cellular_componenthost cell Golgi membrane
A0044423cellular_componentvirion component
A0052031biological_processsymbiont-mediated perturbation of host defense response
A0055036cellular_componentvirion membrane
A0140311molecular_functionprotein sequestering activity
B0005515molecular_functionprotein binding
B0005886cellular_componentplasma membrane
B0016020cellular_componentmembrane
B0019031cellular_componentviral envelope
B0030430cellular_componenthost cell cytoplasm
B0033644cellular_componenthost cell membrane
B0039545biological_processsymbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
B0039660molecular_functionstructural constituent of virion
B0042802molecular_functionidentical protein binding
B0044178cellular_componenthost cell Golgi membrane
B0044423cellular_componentvirion component
B0052031biological_processsymbiont-mediated perturbation of host defense response
B0055036cellular_componentvirion membrane
B0140311molecular_functionprotein sequestering activity
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues146
DetailsTransmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"36264056","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues14
DetailsTopological domain: {"description":"Intravirion","evidences":[{"source":"PubMed","id":"36264056","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues8
DetailsTopological domain: {"description":"Virion surface","evidences":[{"source":"PubMed","id":"36264056","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

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PDB entries from 2025-12-24

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