8CT1

CryoEM structure of human S-OPA1 assembled on lipid membrane in membrane-adjacent state

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
a	0000002	biological_process	mitochondrial genome maintenance
a	0000266	biological_process	mitochondrial fission
a	0000287	molecular_function	magnesium ion binding
a	0001843	biological_process	neural tube closure
a	0003924	molecular_function	GTPase activity
a	0005515	molecular_function	protein binding
a	0005525	molecular_function	GTP binding
a	0005654	cellular_component	nucleoplasm
a	0005737	cellular_component	cytoplasm
a	0005739	cellular_component	mitochondrion
a	0005741	cellular_component	mitochondrial outer membrane
a	0005743	cellular_component	mitochondrial inner membrane
a	0005758	cellular_component	mitochondrial intermembrane space
a	0005829	cellular_component	cytosol
a	0005874	cellular_component	microtubule
a	0006915	biological_process	apoptotic process
a	0007005	biological_process	mitochondrion organization
a	0007007	biological_process	inner mitochondrial membrane organization
a	0007601	biological_process	visual perception
a	0008017	molecular_function	microtubule binding
a	0008053	biological_process	mitochondrial fusion
a	0008289	molecular_function	lipid binding
a	0016020	cellular_component	membrane
a	0016787	molecular_function	hydrolase activity
a	0019896	biological_process	axonal transport of mitochondrion
a	0030061	cellular_component	mitochondrial crista
a	0030425	cellular_component	dendrite
a	0031966	cellular_component	mitochondrial membrane
a	0032740	biological_process	positive regulation of interleukin-17 production
a	0042407	biological_process	cristae formation
a	0043066	biological_process	negative regulation of apoptotic process
a	0046039	biological_process	GTP metabolic process
a	0051259	biological_process	protein complex oligomerization
a	0061025	biological_process	membrane fusion
a	0070300	molecular_function	phosphatidic acid binding
a	0090201	biological_process	negative regulation of release of cytochrome c from mitochondria
a	0090398	biological_process	cellular senescence
a	0097749	biological_process	membrane tubulation
a	0140523	molecular_function	GTPase-dependent fusogenic activity
a	0180020	molecular_function	membrane bending activity
a	1901612	molecular_function	cardiolipin binding
a	1902236	biological_process	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
a	1904115	cellular_component	axon cytoplasm
a	1990627	biological_process	mitochondrial inner membrane fusion
a	2000330	biological_process	positive regulation of T-helper 17 cell lineage commitment
a	2001243	biological_process	negative regulation of intrinsic apoptotic signaling pathway
A	0000002	biological_process	mitochondrial genome maintenance
A	0000266	biological_process	mitochondrial fission
A	0000287	molecular_function	magnesium ion binding
A	0001843	biological_process	neural tube closure
A	0003924	molecular_function	GTPase activity
A	0005515	molecular_function	protein binding
A	0005525	molecular_function	GTP binding
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005741	cellular_component	mitochondrial outer membrane
A	0005743	cellular_component	mitochondrial inner membrane
A	0005758	cellular_component	mitochondrial intermembrane space
A	0005829	cellular_component	cytosol
A	0005874	cellular_component	microtubule
A	0006915	biological_process	apoptotic process
A	0007005	biological_process	mitochondrion organization
A	0007007	biological_process	inner mitochondrial membrane organization
A	0007601	biological_process	visual perception
A	0008017	molecular_function	microtubule binding
A	0008053	biological_process	mitochondrial fusion
A	0008289	molecular_function	lipid binding
A	0016020	cellular_component	membrane
A	0016787	molecular_function	hydrolase activity
A	0019896	biological_process	axonal transport of mitochondrion
A	0030061	cellular_component	mitochondrial crista
A	0030425	cellular_component	dendrite
A	0031966	cellular_component	mitochondrial membrane
A	0032740	biological_process	positive regulation of interleukin-17 production
A	0042407	biological_process	cristae formation
A	0043066	biological_process	negative regulation of apoptotic process
A	0046039	biological_process	GTP metabolic process
A	0051259	biological_process	protein complex oligomerization
A	0061025	biological_process	membrane fusion
A	0070300	molecular_function	phosphatidic acid binding
A	0090201	biological_process	negative regulation of release of cytochrome c from mitochondria
A	0090398	biological_process	cellular senescence
A	0097749	biological_process	membrane tubulation
A	0140523	molecular_function	GTPase-dependent fusogenic activity
A	0180020	molecular_function	membrane bending activity
A	1901612	molecular_function	cardiolipin binding
A	1902236	biological_process	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
A	1904115	cellular_component	axon cytoplasm
A	1990627	biological_process	mitochondrial inner membrane fusion
A	2000330	biological_process	positive regulation of T-helper 17 cell lineage commitment
A	2001243	biological_process	negative regulation of intrinsic apoptotic signaling pathway
b	0000002	biological_process	mitochondrial genome maintenance
b	0000266	biological_process	mitochondrial fission
b	0000287	molecular_function	magnesium ion binding
b	0001843	biological_process	neural tube closure
b	0003924	molecular_function	GTPase activity
b	0005515	molecular_function	protein binding
b	0005525	molecular_function	GTP binding
b	0005654	cellular_component	nucleoplasm
b	0005737	cellular_component	cytoplasm
b	0005739	cellular_component	mitochondrion
b	0005741	cellular_component	mitochondrial outer membrane
b	0005743	cellular_component	mitochondrial inner membrane
b	0005758	cellular_component	mitochondrial intermembrane space
b	0005829	cellular_component	cytosol
b	0005874	cellular_component	microtubule
b	0006915	biological_process	apoptotic process
b	0007005	biological_process	mitochondrion organization
b	0007007	biological_process	inner mitochondrial membrane organization
b	0007601	biological_process	visual perception
b	0008017	molecular_function	microtubule binding
b	0008053	biological_process	mitochondrial fusion
b	0008289	molecular_function	lipid binding
b	0016020	cellular_component	membrane
b	0016787	molecular_function	hydrolase activity
b	0019896	biological_process	axonal transport of mitochondrion
b	0030061	cellular_component	mitochondrial crista
b	0030425	cellular_component	dendrite
b	0031966	cellular_component	mitochondrial membrane
b	0032740	biological_process	positive regulation of interleukin-17 production
b	0042407	biological_process	cristae formation
b	0043066	biological_process	negative regulation of apoptotic process
b	0046039	biological_process	GTP metabolic process
b	0051259	biological_process	protein complex oligomerization
b	0061025	biological_process	membrane fusion
b	0070300	molecular_function	phosphatidic acid binding
b	0090201	biological_process	negative regulation of release of cytochrome c from mitochondria
b	0090398	biological_process	cellular senescence
b	0097749	biological_process	membrane tubulation
b	0140523	molecular_function	GTPase-dependent fusogenic activity
b	0180020	molecular_function	membrane bending activity
b	1901612	molecular_function	cardiolipin binding
b	1902236	biological_process	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
b	1904115	cellular_component	axon cytoplasm
b	1990627	biological_process	mitochondrial inner membrane fusion
b	2000330	biological_process	positive regulation of T-helper 17 cell lineage commitment
b	2001243	biological_process	negative regulation of intrinsic apoptotic signaling pathway
B	0000002	biological_process	mitochondrial genome maintenance
B	0000266	biological_process	mitochondrial fission
B	0000287	molecular_function	magnesium ion binding
B	0001843	biological_process	neural tube closure
B	0003924	molecular_function	GTPase activity
B	0005515	molecular_function	protein binding
B	0005525	molecular_function	GTP binding
B	0005654	cellular_component	nucleoplasm
B	0005737	cellular_component	cytoplasm
B	0005739	cellular_component	mitochondrion
B	0005741	cellular_component	mitochondrial outer membrane
B	0005743	cellular_component	mitochondrial inner membrane
B	0005758	cellular_component	mitochondrial intermembrane space
B	0005829	cellular_component	cytosol
B	0005874	cellular_component	microtubule
B	0006915	biological_process	apoptotic process
B	0007005	biological_process	mitochondrion organization
B	0007007	biological_process	inner mitochondrial membrane organization
B	0007601	biological_process	visual perception
B	0008017	molecular_function	microtubule binding
B	0008053	biological_process	mitochondrial fusion
B	0008289	molecular_function	lipid binding
B	0016020	cellular_component	membrane
B	0016787	molecular_function	hydrolase activity
B	0019896	biological_process	axonal transport of mitochondrion
B	0030061	cellular_component	mitochondrial crista
B	0030425	cellular_component	dendrite
B	0031966	cellular_component	mitochondrial membrane
B	0032740	biological_process	positive regulation of interleukin-17 production
B	0042407	biological_process	cristae formation
B	0043066	biological_process	negative regulation of apoptotic process
B	0046039	biological_process	GTP metabolic process
B	0051259	biological_process	protein complex oligomerization
B	0061025	biological_process	membrane fusion
B	0070300	molecular_function	phosphatidic acid binding
B	0090201	biological_process	negative regulation of release of cytochrome c from mitochondria
B	0090398	biological_process	cellular senescence
B	0097749	biological_process	membrane tubulation
B	0140523	molecular_function	GTPase-dependent fusogenic activity
B	0180020	molecular_function	membrane bending activity
B	1901612	molecular_function	cardiolipin binding
B	1902236	biological_process	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
B	1904115	cellular_component	axon cytoplasm
B	1990627	biological_process	mitochondrial inner membrane fusion
B	2000330	biological_process	positive regulation of T-helper 17 cell lineage commitment
B	2001243	biological_process	negative regulation of intrinsic apoptotic signaling pathway
c	0000002	biological_process	mitochondrial genome maintenance
c	0000266	biological_process	mitochondrial fission
c	0000287	molecular_function	magnesium ion binding
c	0001843	biological_process	neural tube closure
c	0003924	molecular_function	GTPase activity
c	0005515	molecular_function	protein binding
c	0005525	molecular_function	GTP binding
c	0005654	cellular_component	nucleoplasm
c	0005737	cellular_component	cytoplasm
c	0005739	cellular_component	mitochondrion
c	0005741	cellular_component	mitochondrial outer membrane
c	0005743	cellular_component	mitochondrial inner membrane
c	0005758	cellular_component	mitochondrial intermembrane space
c	0005829	cellular_component	cytosol
c	0005874	cellular_component	microtubule
c	0006915	biological_process	apoptotic process
c	0007005	biological_process	mitochondrion organization
c	0007007	biological_process	inner mitochondrial membrane organization
c	0007601	biological_process	visual perception
c	0008017	molecular_function	microtubule binding
c	0008053	biological_process	mitochondrial fusion
c	0008289	molecular_function	lipid binding
c	0016020	cellular_component	membrane
c	0016787	molecular_function	hydrolase activity
c	0019896	biological_process	axonal transport of mitochondrion
c	0030061	cellular_component	mitochondrial crista
c	0030425	cellular_component	dendrite
c	0031966	cellular_component	mitochondrial membrane
c	0032740	biological_process	positive regulation of interleukin-17 production
c	0042407	biological_process	cristae formation
c	0043066	biological_process	negative regulation of apoptotic process
c	0046039	biological_process	GTP metabolic process
c	0051259	biological_process	protein complex oligomerization
c	0061025	biological_process	membrane fusion
c	0070300	molecular_function	phosphatidic acid binding
c	0090201	biological_process	negative regulation of release of cytochrome c from mitochondria
c	0090398	biological_process	cellular senescence
c	0097749	biological_process	membrane tubulation
c	0140523	molecular_function	GTPase-dependent fusogenic activity
c	0180020	molecular_function	membrane bending activity
c	1901612	molecular_function	cardiolipin binding
c	1902236	biological_process	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
c	1904115	cellular_component	axon cytoplasm
c	1990627	biological_process	mitochondrial inner membrane fusion
c	2000330	biological_process	positive regulation of T-helper 17 cell lineage commitment
c	2001243	biological_process	negative regulation of intrinsic apoptotic signaling pathway
C	0000002	biological_process	mitochondrial genome maintenance
C	0000266	biological_process	mitochondrial fission
C	0000287	molecular_function	magnesium ion binding
C	0001843	biological_process	neural tube closure
C	0003924	molecular_function	GTPase activity
C	0005515	molecular_function	protein binding
C	0005525	molecular_function	GTP binding
C	0005654	cellular_component	nucleoplasm
C	0005737	cellular_component	cytoplasm
C	0005739	cellular_component	mitochondrion
C	0005741	cellular_component	mitochondrial outer membrane
C	0005743	cellular_component	mitochondrial inner membrane
C	0005758	cellular_component	mitochondrial intermembrane space
C	0005829	cellular_component	cytosol
C	0005874	cellular_component	microtubule
C	0006915	biological_process	apoptotic process
C	0007005	biological_process	mitochondrion organization
C	0007007	biological_process	inner mitochondrial membrane organization
C	0007601	biological_process	visual perception
C	0008017	molecular_function	microtubule binding
C	0008053	biological_process	mitochondrial fusion
C	0008289	molecular_function	lipid binding
C	0016020	cellular_component	membrane
C	0016787	molecular_function	hydrolase activity
C	0019896	biological_process	axonal transport of mitochondrion
C	0030061	cellular_component	mitochondrial crista
C	0030425	cellular_component	dendrite
C	0031966	cellular_component	mitochondrial membrane
C	0032740	biological_process	positive regulation of interleukin-17 production
C	0042407	biological_process	cristae formation
C	0043066	biological_process	negative regulation of apoptotic process
C	0046039	biological_process	GTP metabolic process
C	0051259	biological_process	protein complex oligomerization
C	0061025	biological_process	membrane fusion
C	0070300	molecular_function	phosphatidic acid binding
C	0090201	biological_process	negative regulation of release of cytochrome c from mitochondria
C	0090398	biological_process	cellular senescence
C	0097749	biological_process	membrane tubulation
C	0140523	molecular_function	GTPase-dependent fusogenic activity
C	0180020	molecular_function	membrane bending activity
C	1901612	molecular_function	cardiolipin binding
C	1902236	biological_process	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
C	1904115	cellular_component	axon cytoplasm
C	1990627	biological_process	mitochondrial inner membrane fusion
C	2000330	biological_process	positive regulation of T-helper 17 cell lineage commitment
C	2001243	biological_process	negative regulation of intrinsic apoptotic signaling pathway
d	0000002	biological_process	mitochondrial genome maintenance
d	0000266	biological_process	mitochondrial fission
d	0000287	molecular_function	magnesium ion binding
d	0001843	biological_process	neural tube closure
d	0003924	molecular_function	GTPase activity
d	0005515	molecular_function	protein binding
d	0005525	molecular_function	GTP binding
d	0005654	cellular_component	nucleoplasm
d	0005737	cellular_component	cytoplasm
d	0005739	cellular_component	mitochondrion
d	0005741	cellular_component	mitochondrial outer membrane
d	0005743	cellular_component	mitochondrial inner membrane
d	0005758	cellular_component	mitochondrial intermembrane space
d	0005829	cellular_component	cytosol
d	0005874	cellular_component	microtubule
d	0006915	biological_process	apoptotic process
d	0007005	biological_process	mitochondrion organization
d	0007007	biological_process	inner mitochondrial membrane organization
d	0007601	biological_process	visual perception
d	0008017	molecular_function	microtubule binding
d	0008053	biological_process	mitochondrial fusion
d	0008289	molecular_function	lipid binding
d	0016020	cellular_component	membrane
d	0016787	molecular_function	hydrolase activity
d	0019896	biological_process	axonal transport of mitochondrion
d	0030061	cellular_component	mitochondrial crista
d	0030425	cellular_component	dendrite
d	0031966	cellular_component	mitochondrial membrane
d	0032740	biological_process	positive regulation of interleukin-17 production
d	0042407	biological_process	cristae formation
d	0043066	biological_process	negative regulation of apoptotic process
d	0046039	biological_process	GTP metabolic process
d	0051259	biological_process	protein complex oligomerization
d	0061025	biological_process	membrane fusion
d	0070300	molecular_function	phosphatidic acid binding
d	0090201	biological_process	negative regulation of release of cytochrome c from mitochondria
d	0090398	biological_process	cellular senescence
d	0097749	biological_process	membrane tubulation
d	0140523	molecular_function	GTPase-dependent fusogenic activity
d	0180020	molecular_function	membrane bending activity
d	1901612	molecular_function	cardiolipin binding
d	1902236	biological_process	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
d	1904115	cellular_component	axon cytoplasm
d	1990627	biological_process	mitochondrial inner membrane fusion
d	2000330	biological_process	positive regulation of T-helper 17 cell lineage commitment
d	2001243	biological_process	negative regulation of intrinsic apoptotic signaling pathway
D	0000002	biological_process	mitochondrial genome maintenance
D	0000266	biological_process	mitochondrial fission
D	0000287	molecular_function	magnesium ion binding
D	0001843	biological_process	neural tube closure
D	0003924	molecular_function	GTPase activity
D	0005515	molecular_function	protein binding
D	0005525	molecular_function	GTP binding
D	0005654	cellular_component	nucleoplasm
D	0005737	cellular_component	cytoplasm
D	0005739	cellular_component	mitochondrion
D	0005741	cellular_component	mitochondrial outer membrane
D	0005743	cellular_component	mitochondrial inner membrane
D	0005758	cellular_component	mitochondrial intermembrane space
D	0005829	cellular_component	cytosol
D	0005874	cellular_component	microtubule
D	0006915	biological_process	apoptotic process
D	0007005	biological_process	mitochondrion organization
D	0007007	biological_process	inner mitochondrial membrane organization
D	0007601	biological_process	visual perception
D	0008017	molecular_function	microtubule binding
D	0008053	biological_process	mitochondrial fusion
D	0008289	molecular_function	lipid binding
D	0016020	cellular_component	membrane
D	0016787	molecular_function	hydrolase activity
D	0019896	biological_process	axonal transport of mitochondrion
D	0030061	cellular_component	mitochondrial crista
D	0030425	cellular_component	dendrite
D	0031966	cellular_component	mitochondrial membrane
D	0032740	biological_process	positive regulation of interleukin-17 production
D	0042407	biological_process	cristae formation
D	0043066	biological_process	negative regulation of apoptotic process
D	0046039	biological_process	GTP metabolic process
D	0051259	biological_process	protein complex oligomerization
D	0061025	biological_process	membrane fusion
D	0070300	molecular_function	phosphatidic acid binding
D	0090201	biological_process	negative regulation of release of cytochrome c from mitochondria
D	0090398	biological_process	cellular senescence
D	0097749	biological_process	membrane tubulation
D	0140523	molecular_function	GTPase-dependent fusogenic activity
D	0180020	molecular_function	membrane bending activity
D	1901612	molecular_function	cardiolipin binding
D	1902236	biological_process	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
D	1904115	cellular_component	axon cytoplasm
D	1990627	biological_process	mitochondrial inner membrane fusion
D	2000330	biological_process	positive regulation of T-helper 17 cell lineage commitment
D	2001243	biological_process	negative regulation of intrinsic apoptotic signaling pathway
e	0000002	biological_process	mitochondrial genome maintenance
e	0000266	biological_process	mitochondrial fission
e	0000287	molecular_function	magnesium ion binding
e	0001843	biological_process	neural tube closure
e	0003924	molecular_function	GTPase activity
e	0005515	molecular_function	protein binding
e	0005525	molecular_function	GTP binding
e	0005654	cellular_component	nucleoplasm
e	0005737	cellular_component	cytoplasm
e	0005739	cellular_component	mitochondrion
e	0005741	cellular_component	mitochondrial outer membrane
e	0005743	cellular_component	mitochondrial inner membrane
e	0005758	cellular_component	mitochondrial intermembrane space
e	0005829	cellular_component	cytosol
e	0005874	cellular_component	microtubule
e	0006915	biological_process	apoptotic process
e	0007005	biological_process	mitochondrion organization
e	0007007	biological_process	inner mitochondrial membrane organization
e	0007601	biological_process	visual perception
e	0008017	molecular_function	microtubule binding
e	0008053	biological_process	mitochondrial fusion
e	0008289	molecular_function	lipid binding
e	0016020	cellular_component	membrane
e	0016787	molecular_function	hydrolase activity
e	0019896	biological_process	axonal transport of mitochondrion
e	0030061	cellular_component	mitochondrial crista
e	0030425	cellular_component	dendrite
e	0031966	cellular_component	mitochondrial membrane
e	0032740	biological_process	positive regulation of interleukin-17 production
e	0042407	biological_process	cristae formation
e	0043066	biological_process	negative regulation of apoptotic process
e	0046039	biological_process	GTP metabolic process
e	0051259	biological_process	protein complex oligomerization
e	0061025	biological_process	membrane fusion
e	0070300	molecular_function	phosphatidic acid binding
e	0090201	biological_process	negative regulation of release of cytochrome c from mitochondria
e	0090398	biological_process	cellular senescence
e	0097749	biological_process	membrane tubulation
e	0140523	molecular_function	GTPase-dependent fusogenic activity
e	0180020	molecular_function	membrane bending activity
e	1901612	molecular_function	cardiolipin binding
e	1902236	biological_process	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
e	1904115	cellular_component	axon cytoplasm
e	1990627	biological_process	mitochondrial inner membrane fusion
e	2000330	biological_process	positive regulation of T-helper 17 cell lineage commitment
e	2001243	biological_process	negative regulation of intrinsic apoptotic signaling pathway
E	0000002	biological_process	mitochondrial genome maintenance
E	0000266	biological_process	mitochondrial fission
E	0000287	molecular_function	magnesium ion binding
E	0001843	biological_process	neural tube closure
E	0003924	molecular_function	GTPase activity
E	0005515	molecular_function	protein binding
E	0005525	molecular_function	GTP binding
E	0005654	cellular_component	nucleoplasm
E	0005737	cellular_component	cytoplasm
E	0005739	cellular_component	mitochondrion
E	0005741	cellular_component	mitochondrial outer membrane
E	0005743	cellular_component	mitochondrial inner membrane
E	0005758	cellular_component	mitochondrial intermembrane space
E	0005829	cellular_component	cytosol
E	0005874	cellular_component	microtubule
E	0006915	biological_process	apoptotic process
E	0007005	biological_process	mitochondrion organization
E	0007007	biological_process	inner mitochondrial membrane organization
E	0007601	biological_process	visual perception
E	0008017	molecular_function	microtubule binding
E	0008053	biological_process	mitochondrial fusion
E	0008289	molecular_function	lipid binding
E	0016020	cellular_component	membrane
E	0016787	molecular_function	hydrolase activity
E	0019896	biological_process	axonal transport of mitochondrion
E	0030061	cellular_component	mitochondrial crista
E	0030425	cellular_component	dendrite
E	0031966	cellular_component	mitochondrial membrane
E	0032740	biological_process	positive regulation of interleukin-17 production
E	0042407	biological_process	cristae formation
E	0043066	biological_process	negative regulation of apoptotic process
E	0046039	biological_process	GTP metabolic process
E	0051259	biological_process	protein complex oligomerization
E	0061025	biological_process	membrane fusion
E	0070300	molecular_function	phosphatidic acid binding
E	0090201	biological_process	negative regulation of release of cytochrome c from mitochondria
E	0090398	biological_process	cellular senescence
E	0097749	biological_process	membrane tubulation
E	0140523	molecular_function	GTPase-dependent fusogenic activity
E	0180020	molecular_function	membrane bending activity
E	1901612	molecular_function	cardiolipin binding
E	1902236	biological_process	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
E	1904115	cellular_component	axon cytoplasm
E	1990627	biological_process	mitochondrial inner membrane fusion
E	2000330	biological_process	positive regulation of T-helper 17 cell lineage commitment
E	2001243	biological_process	negative regulation of intrinsic apoptotic signaling pathway
f	0000002	biological_process	mitochondrial genome maintenance
f	0000266	biological_process	mitochondrial fission
f	0000287	molecular_function	magnesium ion binding
f	0001843	biological_process	neural tube closure
f	0003924	molecular_function	GTPase activity
f	0005515	molecular_function	protein binding
f	0005525	molecular_function	GTP binding
f	0005654	cellular_component	nucleoplasm
f	0005737	cellular_component	cytoplasm
f	0005739	cellular_component	mitochondrion
f	0005741	cellular_component	mitochondrial outer membrane
f	0005743	cellular_component	mitochondrial inner membrane
f	0005758	cellular_component	mitochondrial intermembrane space
f	0005829	cellular_component	cytosol
f	0005874	cellular_component	microtubule
f	0006915	biological_process	apoptotic process
f	0007005	biological_process	mitochondrion organization
f	0007007	biological_process	inner mitochondrial membrane organization
f	0007601	biological_process	visual perception
f	0008017	molecular_function	microtubule binding
f	0008053	biological_process	mitochondrial fusion
f	0008289	molecular_function	lipid binding
f	0016020	cellular_component	membrane
f	0016787	molecular_function	hydrolase activity
f	0019896	biological_process	axonal transport of mitochondrion
f	0030061	cellular_component	mitochondrial crista
f	0030425	cellular_component	dendrite
f	0031966	cellular_component	mitochondrial membrane
f	0032740	biological_process	positive regulation of interleukin-17 production
f	0042407	biological_process	cristae formation
f	0043066	biological_process	negative regulation of apoptotic process
f	0046039	biological_process	GTP metabolic process
f	0051259	biological_process	protein complex oligomerization
f	0061025	biological_process	membrane fusion
f	0070300	molecular_function	phosphatidic acid binding
f	0090201	biological_process	negative regulation of release of cytochrome c from mitochondria
f	0090398	biological_process	cellular senescence
f	0097749	biological_process	membrane tubulation
f	0140523	molecular_function	GTPase-dependent fusogenic activity
f	0180020	molecular_function	membrane bending activity
f	1901612	molecular_function	cardiolipin binding
f	1902236	biological_process	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
f	1904115	cellular_component	axon cytoplasm
f	1990627	biological_process	mitochondrial inner membrane fusion
f	2000330	biological_process	positive regulation of T-helper 17 cell lineage commitment
f	2001243	biological_process	negative regulation of intrinsic apoptotic signaling pathway
F	0000002	biological_process	mitochondrial genome maintenance
F	0000266	biological_process	mitochondrial fission
F	0000287	molecular_function	magnesium ion binding
F	0001843	biological_process	neural tube closure
F	0003924	molecular_function	GTPase activity
F	0005515	molecular_function	protein binding
F	0005525	molecular_function	GTP binding
F	0005654	cellular_component	nucleoplasm
F	0005737	cellular_component	cytoplasm
F	0005739	cellular_component	mitochondrion
F	0005741	cellular_component	mitochondrial outer membrane
F	0005743	cellular_component	mitochondrial inner membrane
F	0005758	cellular_component	mitochondrial intermembrane space
F	0005829	cellular_component	cytosol
F	0005874	cellular_component	microtubule
F	0006915	biological_process	apoptotic process
F	0007005	biological_process	mitochondrion organization
F	0007007	biological_process	inner mitochondrial membrane organization
F	0007601	biological_process	visual perception
F	0008017	molecular_function	microtubule binding
F	0008053	biological_process	mitochondrial fusion
F	0008289	molecular_function	lipid binding
F	0016020	cellular_component	membrane
F	0016787	molecular_function	hydrolase activity
F	0019896	biological_process	axonal transport of mitochondrion
F	0030061	cellular_component	mitochondrial crista
F	0030425	cellular_component	dendrite
F	0031966	cellular_component	mitochondrial membrane
F	0032740	biological_process	positive regulation of interleukin-17 production
F	0042407	biological_process	cristae formation
F	0043066	biological_process	negative regulation of apoptotic process
F	0046039	biological_process	GTP metabolic process
F	0051259	biological_process	protein complex oligomerization
F	0061025	biological_process	membrane fusion
F	0070300	molecular_function	phosphatidic acid binding
F	0090201	biological_process	negative regulation of release of cytochrome c from mitochondria
F	0090398	biological_process	cellular senescence
F	0097749	biological_process	membrane tubulation
F	0140523	molecular_function	GTPase-dependent fusogenic activity
F	0180020	molecular_function	membrane bending activity
F	1901612	molecular_function	cardiolipin binding
F	1902236	biological_process	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
F	1904115	cellular_component	axon cytoplasm
F	1990627	biological_process	mitochondrial inner membrane fusion
F	2000330	biological_process	positive regulation of T-helper 17 cell lineage commitment
F	2001243	biological_process	negative regulation of intrinsic apoptotic signaling pathway
g	0000002	biological_process	mitochondrial genome maintenance
g	0000266	biological_process	mitochondrial fission
g	0000287	molecular_function	magnesium ion binding
g	0001843	biological_process	neural tube closure
g	0003924	molecular_function	GTPase activity
g	0005515	molecular_function	protein binding
g	0005525	molecular_function	GTP binding
g	0005654	cellular_component	nucleoplasm
g	0005737	cellular_component	cytoplasm
g	0005739	cellular_component	mitochondrion
g	0005741	cellular_component	mitochondrial outer membrane
g	0005743	cellular_component	mitochondrial inner membrane
g	0005758	cellular_component	mitochondrial intermembrane space
g	0005829	cellular_component	cytosol
g	0005874	cellular_component	microtubule
g	0006915	biological_process	apoptotic process
g	0007005	biological_process	mitochondrion organization
g	0007007	biological_process	inner mitochondrial membrane organization
g	0007601	biological_process	visual perception
g	0008017	molecular_function	microtubule binding
g	0008053	biological_process	mitochondrial fusion
g	0008289	molecular_function	lipid binding
g	0016020	cellular_component	membrane
g	0016787	molecular_function	hydrolase activity
g	0019896	biological_process	axonal transport of mitochondrion
g	0030061	cellular_component	mitochondrial crista
g	0030425	cellular_component	dendrite
g	0031966	cellular_component	mitochondrial membrane
g	0032740	biological_process	positive regulation of interleukin-17 production
g	0042407	biological_process	cristae formation
g	0043066	biological_process	negative regulation of apoptotic process
g	0046039	biological_process	GTP metabolic process
g	0051259	biological_process	protein complex oligomerization
g	0061025	biological_process	membrane fusion
g	0070300	molecular_function	phosphatidic acid binding
g	0090201	biological_process	negative regulation of release of cytochrome c from mitochondria
g	0090398	biological_process	cellular senescence
g	0097749	biological_process	membrane tubulation
g	0140523	molecular_function	GTPase-dependent fusogenic activity
g	0180020	molecular_function	membrane bending activity
g	1901612	molecular_function	cardiolipin binding
g	1902236	biological_process	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
g	1904115	cellular_component	axon cytoplasm
g	1990627	biological_process	mitochondrial inner membrane fusion
g	2000330	biological_process	positive regulation of T-helper 17 cell lineage commitment
g	2001243	biological_process	negative regulation of intrinsic apoptotic signaling pathway
G	0000002	biological_process	mitochondrial genome maintenance
G	0000266	biological_process	mitochondrial fission
G	0000287	molecular_function	magnesium ion binding
G	0001843	biological_process	neural tube closure
G	0003924	molecular_function	GTPase activity
G	0005515	molecular_function	protein binding
G	0005525	molecular_function	GTP binding
G	0005654	cellular_component	nucleoplasm
G	0005737	cellular_component	cytoplasm
G	0005739	cellular_component	mitochondrion
G	0005741	cellular_component	mitochondrial outer membrane
G	0005743	cellular_component	mitochondrial inner membrane
G	0005758	cellular_component	mitochondrial intermembrane space
G	0005829	cellular_component	cytosol
G	0005874	cellular_component	microtubule
G	0006915	biological_process	apoptotic process
G	0007005	biological_process	mitochondrion organization
G	0007007	biological_process	inner mitochondrial membrane organization
G	0007601	biological_process	visual perception
G	0008017	molecular_function	microtubule binding
G	0008053	biological_process	mitochondrial fusion
G	0008289	molecular_function	lipid binding
G	0016020	cellular_component	membrane
G	0016787	molecular_function	hydrolase activity
G	0019896	biological_process	axonal transport of mitochondrion
G	0030061	cellular_component	mitochondrial crista
G	0030425	cellular_component	dendrite
G	0031966	cellular_component	mitochondrial membrane
G	0032740	biological_process	positive regulation of interleukin-17 production
G	0042407	biological_process	cristae formation
G	0043066	biological_process	negative regulation of apoptotic process
G	0046039	biological_process	GTP metabolic process
G	0051259	biological_process	protein complex oligomerization
G	0061025	biological_process	membrane fusion
G	0070300	molecular_function	phosphatidic acid binding
G	0090201	biological_process	negative regulation of release of cytochrome c from mitochondria
G	0090398	biological_process	cellular senescence
G	0097749	biological_process	membrane tubulation
G	0140523	molecular_function	GTPase-dependent fusogenic activity
G	0180020	molecular_function	membrane bending activity
G	1901612	molecular_function	cardiolipin binding
G	1902236	biological_process	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
G	1904115	cellular_component	axon cytoplasm
G	1990627	biological_process	mitochondrial inner membrane fusion
G	2000330	biological_process	positive regulation of T-helper 17 cell lineage commitment
G	2001243	biological_process	negative regulation of intrinsic apoptotic signaling pathway
h	0000002	biological_process	mitochondrial genome maintenance
h	0000266	biological_process	mitochondrial fission
h	0000287	molecular_function	magnesium ion binding
h	0001843	biological_process	neural tube closure
h	0003924	molecular_function	GTPase activity
h	0005515	molecular_function	protein binding
h	0005525	molecular_function	GTP binding
h	0005654	cellular_component	nucleoplasm
h	0005737	cellular_component	cytoplasm
h	0005739	cellular_component	mitochondrion
h	0005741	cellular_component	mitochondrial outer membrane
h	0005743	cellular_component	mitochondrial inner membrane
h	0005758	cellular_component	mitochondrial intermembrane space
h	0005829	cellular_component	cytosol
h	0005874	cellular_component	microtubule
h	0006915	biological_process	apoptotic process
h	0007005	biological_process	mitochondrion organization
h	0007007	biological_process	inner mitochondrial membrane organization
h	0007601	biological_process	visual perception
h	0008017	molecular_function	microtubule binding
h	0008053	biological_process	mitochondrial fusion
h	0008289	molecular_function	lipid binding
h	0016020	cellular_component	membrane
h	0016787	molecular_function	hydrolase activity
h	0019896	biological_process	axonal transport of mitochondrion
h	0030061	cellular_component	mitochondrial crista
h	0030425	cellular_component	dendrite
h	0031966	cellular_component	mitochondrial membrane
h	0032740	biological_process	positive regulation of interleukin-17 production
h	0042407	biological_process	cristae formation
h	0043066	biological_process	negative regulation of apoptotic process
h	0046039	biological_process	GTP metabolic process
h	0051259	biological_process	protein complex oligomerization
h	0061025	biological_process	membrane fusion
h	0070300	molecular_function	phosphatidic acid binding
h	0090201	biological_process	negative regulation of release of cytochrome c from mitochondria
h	0090398	biological_process	cellular senescence
h	0097749	biological_process	membrane tubulation
h	0140523	molecular_function	GTPase-dependent fusogenic activity
h	0180020	molecular_function	membrane bending activity
h	1901612	molecular_function	cardiolipin binding
h	1902236	biological_process	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
h	1904115	cellular_component	axon cytoplasm
h	1990627	biological_process	mitochondrial inner membrane fusion
h	2000330	biological_process	positive regulation of T-helper 17 cell lineage commitment
h	2001243	biological_process	negative regulation of intrinsic apoptotic signaling pathway
H	0000002	biological_process	mitochondrial genome maintenance
H	0000266	biological_process	mitochondrial fission
H	0000287	molecular_function	magnesium ion binding
H	0001843	biological_process	neural tube closure
H	0003924	molecular_function	GTPase activity
H	0005515	molecular_function	protein binding
H	0005525	molecular_function	GTP binding
H	0005654	cellular_component	nucleoplasm
H	0005737	cellular_component	cytoplasm
H	0005739	cellular_component	mitochondrion
H	0005741	cellular_component	mitochondrial outer membrane
H	0005743	cellular_component	mitochondrial inner membrane
H	0005758	cellular_component	mitochondrial intermembrane space
H	0005829	cellular_component	cytosol
H	0005874	cellular_component	microtubule
H	0006915	biological_process	apoptotic process
H	0007005	biological_process	mitochondrion organization
H	0007007	biological_process	inner mitochondrial membrane organization
H	0007601	biological_process	visual perception
H	0008017	molecular_function	microtubule binding
H	0008053	biological_process	mitochondrial fusion
H	0008289	molecular_function	lipid binding
H	0016020	cellular_component	membrane
H	0016787	molecular_function	hydrolase activity
H	0019896	biological_process	axonal transport of mitochondrion
H	0030061	cellular_component	mitochondrial crista
H	0030425	cellular_component	dendrite
H	0031966	cellular_component	mitochondrial membrane
H	0032740	biological_process	positive regulation of interleukin-17 production
H	0042407	biological_process	cristae formation
H	0043066	biological_process	negative regulation of apoptotic process
H	0046039	biological_process	GTP metabolic process
H	0051259	biological_process	protein complex oligomerization
H	0061025	biological_process	membrane fusion
H	0070300	molecular_function	phosphatidic acid binding
H	0090201	biological_process	negative regulation of release of cytochrome c from mitochondria
H	0090398	biological_process	cellular senescence
H	0097749	biological_process	membrane tubulation
H	0140523	molecular_function	GTPase-dependent fusogenic activity
H	0180020	molecular_function	membrane bending activity
H	1901612	molecular_function	cardiolipin binding
H	1902236	biological_process	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
H	1904115	cellular_component	axon cytoplasm
H	1990627	biological_process	mitochondrial inner membrane fusion
H	2000330	biological_process	positive regulation of T-helper 17 cell lineage commitment
H	2001243	biological_process	negative regulation of intrinsic apoptotic signaling pathway
I	0000002	biological_process	mitochondrial genome maintenance
I	0000266	biological_process	mitochondrial fission
I	0000287	molecular_function	magnesium ion binding
I	0001843	biological_process	neural tube closure
I	0003924	molecular_function	GTPase activity
I	0005515	molecular_function	protein binding
I	0005525	molecular_function	GTP binding
I	0005654	cellular_component	nucleoplasm
I	0005737	cellular_component	cytoplasm
I	0005739	cellular_component	mitochondrion
I	0005741	cellular_component	mitochondrial outer membrane
I	0005743	cellular_component	mitochondrial inner membrane
I	0005758	cellular_component	mitochondrial intermembrane space
I	0005829	cellular_component	cytosol
I	0005874	cellular_component	microtubule
I	0006915	biological_process	apoptotic process
I	0007005	biological_process	mitochondrion organization
I	0007007	biological_process	inner mitochondrial membrane organization
I	0007601	biological_process	visual perception
I	0008017	molecular_function	microtubule binding
I	0008053	biological_process	mitochondrial fusion
I	0008289	molecular_function	lipid binding
I	0016020	cellular_component	membrane
I	0016787	molecular_function	hydrolase activity
I	0019896	biological_process	axonal transport of mitochondrion
I	0030061	cellular_component	mitochondrial crista
I	0030425	cellular_component	dendrite
I	0031966	cellular_component	mitochondrial membrane
I	0032740	biological_process	positive regulation of interleukin-17 production
I	0042407	biological_process	cristae formation
I	0043066	biological_process	negative regulation of apoptotic process
I	0046039	biological_process	GTP metabolic process
I	0051259	biological_process	protein complex oligomerization
I	0061025	biological_process	membrane fusion
I	0070300	molecular_function	phosphatidic acid binding
I	0090201	biological_process	negative regulation of release of cytochrome c from mitochondria
I	0090398	biological_process	cellular senescence
I	0097749	biological_process	membrane tubulation
I	0140523	molecular_function	GTPase-dependent fusogenic activity
I	0180020	molecular_function	membrane bending activity
I	1901612	molecular_function	cardiolipin binding
I	1902236	biological_process	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
I	1904115	cellular_component	axon cytoplasm
I	1990627	biological_process	mitochondrial inner membrane fusion
I	2000330	biological_process	positive regulation of T-helper 17 cell lineage commitment
I	2001243	biological_process	negative regulation of intrinsic apoptotic signaling pathway
J	0000002	biological_process	mitochondrial genome maintenance
J	0000266	biological_process	mitochondrial fission
J	0000287	molecular_function	magnesium ion binding
J	0001843	biological_process	neural tube closure
J	0003924	molecular_function	GTPase activity
J	0005515	molecular_function	protein binding
J	0005525	molecular_function	GTP binding
J	0005654	cellular_component	nucleoplasm
J	0005737	cellular_component	cytoplasm
J	0005739	cellular_component	mitochondrion
J	0005741	cellular_component	mitochondrial outer membrane
J	0005743	cellular_component	mitochondrial inner membrane
J	0005758	cellular_component	mitochondrial intermembrane space
J	0005829	cellular_component	cytosol
J	0005874	cellular_component	microtubule
J	0006915	biological_process	apoptotic process
J	0007005	biological_process	mitochondrion organization
J	0007007	biological_process	inner mitochondrial membrane organization
J	0007601	biological_process	visual perception
J	0008017	molecular_function	microtubule binding
J	0008053	biological_process	mitochondrial fusion
J	0008289	molecular_function	lipid binding
J	0016020	cellular_component	membrane
J	0016787	molecular_function	hydrolase activity
J	0019896	biological_process	axonal transport of mitochondrion
J	0030061	cellular_component	mitochondrial crista
J	0030425	cellular_component	dendrite
J	0031966	cellular_component	mitochondrial membrane
J	0032740	biological_process	positive regulation of interleukin-17 production
J	0042407	biological_process	cristae formation
J	0043066	biological_process	negative regulation of apoptotic process
J	0046039	biological_process	GTP metabolic process
J	0051259	biological_process	protein complex oligomerization
J	0061025	biological_process	membrane fusion
J	0070300	molecular_function	phosphatidic acid binding
J	0090201	biological_process	negative regulation of release of cytochrome c from mitochondria
J	0090398	biological_process	cellular senescence
J	0097749	biological_process	membrane tubulation
J	0140523	molecular_function	GTPase-dependent fusogenic activity
J	0180020	molecular_function	membrane bending activity
J	1901612	molecular_function	cardiolipin binding
J	1902236	biological_process	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
J	1904115	cellular_component	axon cytoplasm
J	1990627	biological_process	mitochondrial inner membrane fusion
J	2000330	biological_process	positive regulation of T-helper 17 cell lineage commitment
J	2001243	biological_process	negative regulation of intrinsic apoptotic signaling pathway
K	0000002	biological_process	mitochondrial genome maintenance
K	0000266	biological_process	mitochondrial fission
K	0000287	molecular_function	magnesium ion binding
K	0001843	biological_process	neural tube closure
K	0003924	molecular_function	GTPase activity
K	0005515	molecular_function	protein binding
K	0005525	molecular_function	GTP binding
K	0005654	cellular_component	nucleoplasm
K	0005737	cellular_component	cytoplasm
K	0005739	cellular_component	mitochondrion
K	0005741	cellular_component	mitochondrial outer membrane
K	0005743	cellular_component	mitochondrial inner membrane
K	0005758	cellular_component	mitochondrial intermembrane space
K	0005829	cellular_component	cytosol
K	0005874	cellular_component	microtubule
K	0006915	biological_process	apoptotic process
K	0007005	biological_process	mitochondrion organization
K	0007007	biological_process	inner mitochondrial membrane organization
K	0007601	biological_process	visual perception
K	0008017	molecular_function	microtubule binding
K	0008053	biological_process	mitochondrial fusion
K	0008289	molecular_function	lipid binding
K	0016020	cellular_component	membrane
K	0016787	molecular_function	hydrolase activity
K	0019896	biological_process	axonal transport of mitochondrion
K	0030061	cellular_component	mitochondrial crista
K	0030425	cellular_component	dendrite
K	0031966	cellular_component	mitochondrial membrane
K	0032740	biological_process	positive regulation of interleukin-17 production
K	0042407	biological_process	cristae formation
K	0043066	biological_process	negative regulation of apoptotic process
K	0046039	biological_process	GTP metabolic process
K	0051259	biological_process	protein complex oligomerization
K	0061025	biological_process	membrane fusion
K	0070300	molecular_function	phosphatidic acid binding
K	0090201	biological_process	negative regulation of release of cytochrome c from mitochondria
K	0090398	biological_process	cellular senescence
K	0097749	biological_process	membrane tubulation
K	0140523	molecular_function	GTPase-dependent fusogenic activity
K	0180020	molecular_function	membrane bending activity
K	1901612	molecular_function	cardiolipin binding
K	1902236	biological_process	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
K	1904115	cellular_component	axon cytoplasm
K	1990627	biological_process	mitochondrial inner membrane fusion
K	2000330	biological_process	positive regulation of T-helper 17 cell lineage commitment
K	2001243	biological_process	negative regulation of intrinsic apoptotic signaling pathway
L	0000002	biological_process	mitochondrial genome maintenance
L	0000266	biological_process	mitochondrial fission
L	0000287	molecular_function	magnesium ion binding
L	0001843	biological_process	neural tube closure
L	0003924	molecular_function	GTPase activity
L	0005515	molecular_function	protein binding
L	0005525	molecular_function	GTP binding
L	0005654	cellular_component	nucleoplasm
L	0005737	cellular_component	cytoplasm
L	0005739	cellular_component	mitochondrion
L	0005741	cellular_component	mitochondrial outer membrane
L	0005743	cellular_component	mitochondrial inner membrane
L	0005758	cellular_component	mitochondrial intermembrane space
L	0005829	cellular_component	cytosol
L	0005874	cellular_component	microtubule
L	0006915	biological_process	apoptotic process
L	0007005	biological_process	mitochondrion organization
L	0007007	biological_process	inner mitochondrial membrane organization
L	0007601	biological_process	visual perception
L	0008017	molecular_function	microtubule binding
L	0008053	biological_process	mitochondrial fusion
L	0008289	molecular_function	lipid binding
L	0016020	cellular_component	membrane
L	0016787	molecular_function	hydrolase activity
L	0019896	biological_process	axonal transport of mitochondrion
L	0030061	cellular_component	mitochondrial crista
L	0030425	cellular_component	dendrite
L	0031966	cellular_component	mitochondrial membrane
L	0032740	biological_process	positive regulation of interleukin-17 production
L	0042407	biological_process	cristae formation
L	0043066	biological_process	negative regulation of apoptotic process
L	0046039	biological_process	GTP metabolic process
L	0051259	biological_process	protein complex oligomerization
L	0061025	biological_process	membrane fusion
L	0070300	molecular_function	phosphatidic acid binding
L	0090201	biological_process	negative regulation of release of cytochrome c from mitochondria
L	0090398	biological_process	cellular senescence
L	0097749	biological_process	membrane tubulation
L	0140523	molecular_function	GTPase-dependent fusogenic activity
L	0180020	molecular_function	membrane bending activity
L	1901612	molecular_function	cardiolipin binding
L	1902236	biological_process	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
L	1904115	cellular_component	axon cytoplasm
L	1990627	biological_process	mitochondrial inner membrane fusion
L	2000330	biological_process	positive regulation of T-helper 17 cell lineage commitment
L	2001243	biological_process	negative regulation of intrinsic apoptotic signaling pathway
M	0000002	biological_process	mitochondrial genome maintenance
M	0000266	biological_process	mitochondrial fission
M	0000287	molecular_function	magnesium ion binding
M	0001843	biological_process	neural tube closure
M	0003924	molecular_function	GTPase activity
M	0005515	molecular_function	protein binding
M	0005525	molecular_function	GTP binding
M	0005654	cellular_component	nucleoplasm
M	0005737	cellular_component	cytoplasm
M	0005739	cellular_component	mitochondrion
M	0005741	cellular_component	mitochondrial outer membrane
M	0005743	cellular_component	mitochondrial inner membrane
M	0005758	cellular_component	mitochondrial intermembrane space
M	0005829	cellular_component	cytosol
M	0005874	cellular_component	microtubule
M	0006915	biological_process	apoptotic process
M	0007005	biological_process	mitochondrion organization
M	0007007	biological_process	inner mitochondrial membrane organization
M	0007601	biological_process	visual perception
M	0008017	molecular_function	microtubule binding
M	0008053	biological_process	mitochondrial fusion
M	0008289	molecular_function	lipid binding
M	0016020	cellular_component	membrane
M	0016787	molecular_function	hydrolase activity
M	0019896	biological_process	axonal transport of mitochondrion
M	0030061	cellular_component	mitochondrial crista
M	0030425	cellular_component	dendrite
M	0031966	cellular_component	mitochondrial membrane
M	0032740	biological_process	positive regulation of interleukin-17 production
M	0042407	biological_process	cristae formation
M	0043066	biological_process	negative regulation of apoptotic process
M	0046039	biological_process	GTP metabolic process
M	0051259	biological_process	protein complex oligomerization
M	0061025	biological_process	membrane fusion
M	0070300	molecular_function	phosphatidic acid binding
M	0090201	biological_process	negative regulation of release of cytochrome c from mitochondria
M	0090398	biological_process	cellular senescence
M	0097749	biological_process	membrane tubulation
M	0140523	molecular_function	GTPase-dependent fusogenic activity
M	0180020	molecular_function	membrane bending activity
M	1901612	molecular_function	cardiolipin binding
M	1902236	biological_process	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
M	1904115	cellular_component	axon cytoplasm
M	1990627	biological_process	mitochondrial inner membrane fusion
M	2000330	biological_process	positive regulation of T-helper 17 cell lineage commitment
M	2001243	biological_process	negative regulation of intrinsic apoptotic signaling pathway
N	0000002	biological_process	mitochondrial genome maintenance
N	0000266	biological_process	mitochondrial fission
N	0000287	molecular_function	magnesium ion binding
N	0001843	biological_process	neural tube closure
N	0003924	molecular_function	GTPase activity
N	0005515	molecular_function	protein binding
N	0005525	molecular_function	GTP binding
N	0005654	cellular_component	nucleoplasm
N	0005737	cellular_component	cytoplasm
N	0005739	cellular_component	mitochondrion
N	0005741	cellular_component	mitochondrial outer membrane
N	0005743	cellular_component	mitochondrial inner membrane
N	0005758	cellular_component	mitochondrial intermembrane space
N	0005829	cellular_component	cytosol
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N	0051259	biological_process	protein complex oligomerization
N	0061025	biological_process	membrane fusion
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N	0140523	molecular_function	GTPase-dependent fusogenic activity
N	0180020	molecular_function	membrane bending activity
N	1901612	molecular_function	cardiolipin binding
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N	1904115	cellular_component	axon cytoplasm
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O	0007601	biological_process	visual perception
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O	0042407	biological_process	cristae formation
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O	0046039	biological_process	GTP metabolic process
O	0051259	biological_process	protein complex oligomerization
O	0061025	biological_process	membrane fusion
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O	0090398	biological_process	cellular senescence
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O	0140523	molecular_function	GTPase-dependent fusogenic activity
O	0180020	molecular_function	membrane bending activity
O	1901612	molecular_function	cardiolipin binding
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O	1904115	cellular_component	axon cytoplasm
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P	0000002	biological_process	mitochondrial genome maintenance
P	0000266	biological_process	mitochondrial fission
P	0000287	molecular_function	magnesium ion binding
P	0001843	biological_process	neural tube closure
P	0003924	molecular_function	GTPase activity
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P	0005654	cellular_component	nucleoplasm
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P	0005739	cellular_component	mitochondrion
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P	0005743	cellular_component	mitochondrial inner membrane
P	0005758	cellular_component	mitochondrial intermembrane space
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P	0006915	biological_process	apoptotic process
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P	0007007	biological_process	inner mitochondrial membrane organization
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P	0030061	cellular_component	mitochondrial crista
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P	0051259	biological_process	protein complex oligomerization
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P	0180020	molecular_function	membrane bending activity
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Q	0001843	biological_process	neural tube closure
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Q	0005737	cellular_component	cytoplasm
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Q	0005741	cellular_component	mitochondrial outer membrane
Q	0005743	cellular_component	mitochondrial inner membrane
Q	0005758	cellular_component	mitochondrial intermembrane space
Q	0005829	cellular_component	cytosol
Q	0005874	cellular_component	microtubule
Q	0006915	biological_process	apoptotic process
Q	0007005	biological_process	mitochondrion organization
Q	0007007	biological_process	inner mitochondrial membrane organization
Q	0007601	biological_process	visual perception
Q	0008017	molecular_function	microtubule binding
Q	0008053	biological_process	mitochondrial fusion
Q	0008289	molecular_function	lipid binding
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Q	0016787	molecular_function	hydrolase activity
Q	0019896	biological_process	axonal transport of mitochondrion
Q	0030061	cellular_component	mitochondrial crista
Q	0030425	cellular_component	dendrite
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Q	0046039	biological_process	GTP metabolic process
Q	0051259	biological_process	protein complex oligomerization
Q	0061025	biological_process	membrane fusion
Q	0070300	molecular_function	phosphatidic acid binding
Q	0090201	biological_process	negative regulation of release of cytochrome c from mitochondria
Q	0090398	biological_process	cellular senescence
Q	0097749	biological_process	membrane tubulation
Q	0140523	molecular_function	GTPase-dependent fusogenic activity
Q	0180020	molecular_function	membrane bending activity
Q	1901612	molecular_function	cardiolipin binding
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Q	1904115	cellular_component	axon cytoplasm
Q	1990627	biological_process	mitochondrial inner membrane fusion
Q	2000330	biological_process	positive regulation of T-helper 17 cell lineage commitment
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R	0000002	biological_process	mitochondrial genome maintenance
R	0000266	biological_process	mitochondrial fission
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R	0001843	biological_process	neural tube closure
R	0003924	molecular_function	GTPase activity
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R	0005525	molecular_function	GTP binding
R	0005654	cellular_component	nucleoplasm
R	0005737	cellular_component	cytoplasm
R	0005739	cellular_component	mitochondrion
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R	0005743	cellular_component	mitochondrial inner membrane
R	0005758	cellular_component	mitochondrial intermembrane space
R	0005829	cellular_component	cytosol
R	0005874	cellular_component	microtubule
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R	0007005	biological_process	mitochondrion organization
R	0007007	biological_process	inner mitochondrial membrane organization
R	0007601	biological_process	visual perception
R	0008017	molecular_function	microtubule binding
R	0008053	biological_process	mitochondrial fusion
R	0008289	molecular_function	lipid binding
R	0016020	cellular_component	membrane
R	0016787	molecular_function	hydrolase activity
R	0019896	biological_process	axonal transport of mitochondrion
R	0030061	cellular_component	mitochondrial crista
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R	0032740	biological_process	positive regulation of interleukin-17 production
R	0042407	biological_process	cristae formation
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R	0046039	biological_process	GTP metabolic process
R	0051259	biological_process	protein complex oligomerization
R	0061025	biological_process	membrane fusion
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R	0090398	biological_process	cellular senescence
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R	0140523	molecular_function	GTPase-dependent fusogenic activity
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R	1904115	cellular_component	axon cytoplasm
R	1990627	biological_process	mitochondrial inner membrane fusion
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T	0000266	biological_process	mitochondrial fission
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T	0005737	cellular_component	cytoplasm
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T	0005758	cellular_component	mitochondrial intermembrane space
T	0005829	cellular_component	cytosol
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T	0007601	biological_process	visual perception
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T	0008053	biological_process	mitochondrial fusion
T	0008289	molecular_function	lipid binding
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U	0090398	biological_process	cellular senescence
U	0097749	biological_process	membrane tubulation
U	0140523	molecular_function	GTPase-dependent fusogenic activity
U	0180020	molecular_function	membrane bending activity
U	1901612	molecular_function	cardiolipin binding
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U	1904115	cellular_component	axon cytoplasm
U	1990627	biological_process	mitochondrial inner membrane fusion
U	2000330	biological_process	positive regulation of T-helper 17 cell lineage commitment
U	2001243	biological_process	negative regulation of intrinsic apoptotic signaling pathway
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V	0000266	biological_process	mitochondrial fission
V	0000287	molecular_function	magnesium ion binding
V	0001843	biological_process	neural tube closure
V	0003924	molecular_function	GTPase activity
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V	0005525	molecular_function	GTP binding
V	0005654	cellular_component	nucleoplasm
V	0005737	cellular_component	cytoplasm
V	0005739	cellular_component	mitochondrion
V	0005741	cellular_component	mitochondrial outer membrane
V	0005743	cellular_component	mitochondrial inner membrane
V	0005758	cellular_component	mitochondrial intermembrane space
V	0005829	cellular_component	cytosol
V	0005874	cellular_component	microtubule
V	0006915	biological_process	apoptotic process
V	0007005	biological_process	mitochondrion organization
V	0007007	biological_process	inner mitochondrial membrane organization
V	0007601	biological_process	visual perception
V	0008017	molecular_function	microtubule binding
V	0008053	biological_process	mitochondrial fusion
V	0008289	molecular_function	lipid binding
V	0016020	cellular_component	membrane
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V	0019896	biological_process	axonal transport of mitochondrion
V	0030061	cellular_component	mitochondrial crista
V	0030425	cellular_component	dendrite
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V	0032740	biological_process	positive regulation of interleukin-17 production
V	0042407	biological_process	cristae formation
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V	0051259	biological_process	protein complex oligomerization
V	0061025	biological_process	membrane fusion
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V	0090201	biological_process	negative regulation of release of cytochrome c from mitochondria
V	0090398	biological_process	cellular senescence
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V	0140523	molecular_function	GTPase-dependent fusogenic activity
V	0180020	molecular_function	membrane bending activity
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V	1904115	cellular_component	axon cytoplasm
V	1990627	biological_process	mitochondrial inner membrane fusion
V	2000330	biological_process	positive regulation of T-helper 17 cell lineage commitment
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W	0000002	biological_process	mitochondrial genome maintenance
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W	0001843	biological_process	neural tube closure
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X	2001243	biological_process	negative regulation of intrinsic apoptotic signaling pathway
Y	0000002	biological_process	mitochondrial genome maintenance
Y	0000266	biological_process	mitochondrial fission
Y	0000287	molecular_function	magnesium ion binding
Y	0001843	biological_process	neural tube closure
Y	0003924	molecular_function	GTPase activity
Y	0005515	molecular_function	protein binding
Y	0005525	molecular_function	GTP binding
Y	0005654	cellular_component	nucleoplasm
Y	0005737	cellular_component	cytoplasm
Y	0005739	cellular_component	mitochondrion
Y	0005741	cellular_component	mitochondrial outer membrane
Y	0005743	cellular_component	mitochondrial inner membrane
Y	0005758	cellular_component	mitochondrial intermembrane space
Y	0005829	cellular_component	cytosol
Y	0005874	cellular_component	microtubule
Y	0006915	biological_process	apoptotic process
Y	0007005	biological_process	mitochondrion organization
Y	0007007	biological_process	inner mitochondrial membrane organization
Y	0007601	biological_process	visual perception
Y	0008017	molecular_function	microtubule binding
Y	0008053	biological_process	mitochondrial fusion
Y	0008289	molecular_function	lipid binding
Y	0016020	cellular_component	membrane
Y	0016787	molecular_function	hydrolase activity
Y	0019896	biological_process	axonal transport of mitochondrion
Y	0030061	cellular_component	mitochondrial crista
Y	0030425	cellular_component	dendrite
Y	0031966	cellular_component	mitochondrial membrane
Y	0032740	biological_process	positive regulation of interleukin-17 production
Y	0042407	biological_process	cristae formation
Y	0043066	biological_process	negative regulation of apoptotic process
Y	0046039	biological_process	GTP metabolic process
Y	0051259	biological_process	protein complex oligomerization
Y	0061025	biological_process	membrane fusion
Y	0070300	molecular_function	phosphatidic acid binding
Y	0090201	biological_process	negative regulation of release of cytochrome c from mitochondria
Y	0090398	biological_process	cellular senescence
Y	0097749	biological_process	membrane tubulation
Y	0140523	molecular_function	GTPase-dependent fusogenic activity
Y	0180020	molecular_function	membrane bending activity
Y	1901612	molecular_function	cardiolipin binding
Y	1902236	biological_process	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
Y	1904115	cellular_component	axon cytoplasm
Y	1990627	biological_process	mitochondrial inner membrane fusion
Y	2000330	biological_process	positive regulation of T-helper 17 cell lineage commitment
Y	2001243	biological_process	negative regulation of intrinsic apoptotic signaling pathway
Z	0000002	biological_process	mitochondrial genome maintenance
Z	0000266	biological_process	mitochondrial fission
Z	0000287	molecular_function	magnesium ion binding
Z	0001843	biological_process	neural tube closure
Z	0003924	molecular_function	GTPase activity
Z	0005515	molecular_function	protein binding
Z	0005525	molecular_function	GTP binding
Z	0005654	cellular_component	nucleoplasm
Z	0005737	cellular_component	cytoplasm
Z	0005739	cellular_component	mitochondrion
Z	0005741	cellular_component	mitochondrial outer membrane
Z	0005743	cellular_component	mitochondrial inner membrane
Z	0005758	cellular_component	mitochondrial intermembrane space
Z	0005829	cellular_component	cytosol
Z	0005874	cellular_component	microtubule
Z	0006915	biological_process	apoptotic process
Z	0007005	biological_process	mitochondrion organization
Z	0007007	biological_process	inner mitochondrial membrane organization
Z	0007601	biological_process	visual perception
Z	0008017	molecular_function	microtubule binding
Z	0008053	biological_process	mitochondrial fusion
Z	0008289	molecular_function	lipid binding
Z	0016020	cellular_component	membrane
Z	0016787	molecular_function	hydrolase activity
Z	0019896	biological_process	axonal transport of mitochondrion
Z	0030061	cellular_component	mitochondrial crista
Z	0030425	cellular_component	dendrite
Z	0031966	cellular_component	mitochondrial membrane
Z	0032740	biological_process	positive regulation of interleukin-17 production
Z	0042407	biological_process	cristae formation
Z	0043066	biological_process	negative regulation of apoptotic process
Z	0046039	biological_process	GTP metabolic process
Z	0051259	biological_process	protein complex oligomerization
Z	0061025	biological_process	membrane fusion
Z	0070300	molecular_function	phosphatidic acid binding
Z	0090201	biological_process	negative regulation of release of cytochrome c from mitochondria
Z	0090398	biological_process	cellular senescence
Z	0097749	biological_process	membrane tubulation
Z	0140523	molecular_function	GTPase-dependent fusogenic activity
Z	0180020	molecular_function	membrane bending activity
Z	1901612	molecular_function	cardiolipin binding
Z	1902236	biological_process	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
Z	1904115	cellular_component	axon cytoplasm
Z	1990627	biological_process	mitochondrial inner membrane fusion
Z	2000330	biological_process	positive regulation of T-helper 17 cell lineage commitment
Z	2001243	biological_process	negative regulation of intrinsic apoptotic signaling pathway

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	272
Details	TOPO_DOM: Mitochondrial matrix => ECO:0000305|PubMed:37612504, ECO:0000305|PubMed:37612506

Chain	Residue	Details
A	PHE88-ARG96
e	PHE88-ARG96
F	PHE88-ARG96
f	PHE88-ARG96
G	PHE88-ARG96
g	PHE88-ARG96
H	PHE88-ARG96
h	PHE88-ARG96
I	PHE88-ARG96
J	PHE88-ARG96
K	PHE88-ARG96
a	PHE88-ARG96
L	PHE88-ARG96
M	PHE88-ARG96
N	PHE88-ARG96
O	PHE88-ARG96
P	PHE88-ARG96
Q	PHE88-ARG96
R	PHE88-ARG96
S	PHE88-ARG96
T	PHE88-ARG96
U	PHE88-ARG96
B	PHE88-ARG96
V	PHE88-ARG96
W	PHE88-ARG96
X	PHE88-ARG96
Y	PHE88-ARG96
Z	PHE88-ARG96
b	PHE88-ARG96
C	PHE88-ARG96
c	PHE88-ARG96
D	PHE88-ARG96
d	PHE88-ARG96
E	PHE88-ARG96

---

site_id	SWS_FT_FI2
Number of Residues	544
Details	TRANSMEM: Helical => ECO:0000255

Chain	Residue	Details
A	LEU97-TYR113
e	LEU97-TYR113
F	LEU97-TYR113
f	LEU97-TYR113
G	LEU97-TYR113
g	LEU97-TYR113
H	LEU97-TYR113
h	LEU97-TYR113
I	LEU97-TYR113
J	LEU97-TYR113
K	LEU97-TYR113
a	LEU97-TYR113
L	LEU97-TYR113
M	LEU97-TYR113
N	LEU97-TYR113
O	LEU97-TYR113
P	LEU97-TYR113
Q	LEU97-TYR113
R	LEU97-TYR113
S	LEU97-TYR113
T	LEU97-TYR113
U	LEU97-TYR113
B	LEU97-TYR113
V	LEU97-TYR113
W	LEU97-TYR113
X	LEU97-TYR113
Y	LEU97-TYR113
Z	LEU97-TYR113
b	LEU97-TYR113
C	LEU97-TYR113
c	LEU97-TYR113
D	LEU97-TYR113
d	LEU97-TYR113
E	LEU97-TYR113

---

site_id	SWS_FT_FI3
Number of Residues	28356
Details	TOPO_DOM: Mitochondrial intermembrane => ECO:0000305|PubMed:37612504, ECO:0000305|PubMed:37612506

Chain	Residue	Details
A	THR114-ASP770
C	THR782-LYS960
c	THR114-ASP770
c	THR782-LYS960
D	THR114-ASP770
D	THR782-LYS960
d	THR114-ASP770
d	THR782-LYS960
E	THR114-ASP770
E	THR782-LYS960
e	THR114-ASP770
A	THR782-LYS960
e	THR782-LYS960
F	THR114-ASP770
F	THR782-LYS960
f	THR114-ASP770
f	THR782-LYS960
G	THR114-ASP770
G	THR782-LYS960
g	THR114-ASP770
g	THR782-LYS960
H	THR114-ASP770
a	THR114-ASP770
H	THR782-LYS960
h	THR114-ASP770
h	THR782-LYS960
I	THR114-ASP770
I	THR782-LYS960
J	THR114-ASP770
J	THR782-LYS960
K	THR114-ASP770
K	THR782-LYS960
L	THR114-ASP770
a	THR782-LYS960
L	THR782-LYS960
M	THR114-ASP770
M	THR782-LYS960
N	THR114-ASP770
N	THR782-LYS960
O	THR114-ASP770
O	THR782-LYS960
P	THR114-ASP770
P	THR782-LYS960
Q	THR114-ASP770
B	THR114-ASP770
Q	THR782-LYS960
R	THR114-ASP770
R	THR782-LYS960
S	THR114-ASP770
S	THR782-LYS960
T	THR114-ASP770
T	THR782-LYS960
U	THR114-ASP770
U	THR782-LYS960
V	THR114-ASP770
B	THR782-LYS960
V	THR782-LYS960
W	THR114-ASP770
W	THR782-LYS960
X	THR114-ASP770
X	THR782-LYS960
Y	THR114-ASP770
Y	THR782-LYS960
Z	THR114-ASP770
Z	THR782-LYS960
b	THR114-ASP770
b	THR782-LYS960
C	THR114-ASP770

---

site_id	SWS_FT_FI4
Number of Residues	340
Details	INTRAMEM: INTRAMEM => ECO:0000269|PubMed:37612504, ECO:0000269|PubMed:37612506

Chain	Residue	Details
A	TRP771-ARG781
e	TRP771-ARG781
F	TRP771-ARG781
f	TRP771-ARG781
G	TRP771-ARG781
g	TRP771-ARG781
H	TRP771-ARG781
h	TRP771-ARG781
I	TRP771-ARG781
J	TRP771-ARG781
K	TRP771-ARG781
a	TRP771-ARG781
L	TRP771-ARG781
M	TRP771-ARG781
N	TRP771-ARG781
O	TRP771-ARG781
P	TRP771-ARG781
Q	TRP771-ARG781
R	TRP771-ARG781
S	TRP771-ARG781
T	TRP771-ARG781
U	TRP771-ARG781
B	TRP771-ARG781
V	TRP771-ARG781
W	TRP771-ARG781
X	TRP771-ARG781
Y	TRP771-ARG781
Z	TRP771-ARG781
b	TRP771-ARG781
C	TRP771-ARG781
c	TRP771-ARG781
D	TRP771-ARG781
d	TRP771-ARG781
E	TRP771-ARG781

---

site_id	SWS_FT_FI5
Number of Residues	340
Details	BINDING: BINDING => ECO:0000305|PubMed:32379273, ECO:0007744|PDB:6JTG

Chain	Residue	Details
A	SER298
A	THR503
e	THR503
F	SER298
F	GLY300
F	LYS301
F	THR302
F	GLY317
F	THR323
F	ASP398
F	LYS468
F	ASP470
a	SER298
F	THR503
f	SER298
f	GLY300
f	LYS301
f	THR302
f	GLY317
f	THR323
f	ASP398
f	LYS468
f	ASP470
a	GLY300
f	THR503
G	SER298
G	GLY300
G	LYS301
G	THR302
G	GLY317
G	THR323
G	ASP398
G	LYS468
G	ASP470
a	LYS301
G	THR503
g	SER298
g	GLY300
g	LYS301
g	THR302
g	GLY317
g	THR323
g	ASP398
g	LYS468
g	ASP470
a	THR302
g	THR503
H	SER298
H	GLY300
H	LYS301
H	THR302
H	GLY317
H	THR323
H	ASP398
H	LYS468
H	ASP470
a	GLY317
H	THR503
h	SER298
h	GLY300
h	LYS301
h	THR302
h	GLY317
h	THR323
h	ASP398
h	LYS468
h	ASP470
a	THR323
h	THR503
I	SER298
I	GLY300
I	LYS301
I	THR302
I	GLY317
I	THR323
I	ASP398
I	LYS468
I	ASP470
a	ASP398
I	THR503
J	SER298
J	GLY300
J	LYS301
J	THR302
J	GLY317
J	THR323
J	ASP398
J	LYS468
J	ASP470
a	LYS468
J	THR503
K	SER298
K	GLY300
K	LYS301
K	THR302
K	GLY317
K	THR323
K	ASP398
K	LYS468
K	ASP470
a	ASP470
K	THR503
L	SER298
L	GLY300
L	LYS301
L	THR302
L	GLY317
L	THR323
L	ASP398
L	LYS468
L	ASP470
A	GLY300
a	THR503
L	THR503
M	SER298
M	GLY300
M	LYS301
M	THR302
M	GLY317
M	THR323
M	ASP398
M	LYS468
M	ASP470
B	SER298
M	THR503
N	SER298
N	GLY300
N	LYS301
N	THR302
N	GLY317
N	THR323
N	ASP398
N	LYS468
N	ASP470
B	GLY300
N	THR503
O	SER298
O	GLY300
O	LYS301
O	THR302
O	GLY317
O	THR323
O	ASP398
O	LYS468
O	ASP470
B	LYS301
O	THR503
P	SER298
P	GLY300
P	LYS301
P	THR302
P	GLY317
P	THR323
P	ASP398
P	LYS468
P	ASP470
B	THR302
P	THR503
Q	SER298
Q	GLY300
Q	LYS301
Q	THR302
Q	GLY317
Q	THR323
Q	ASP398
Q	LYS468
Q	ASP470
B	GLY317
Q	THR503
R	SER298
R	GLY300
R	LYS301
R	THR302
R	GLY317
R	THR323
R	ASP398
R	LYS468
R	ASP470
B	THR323
R	THR503
S	SER298
S	GLY300
S	LYS301
S	THR302
S	GLY317
S	THR323
S	ASP398
S	LYS468
S	ASP470
B	ASP398
S	THR503
T	SER298
T	GLY300
T	LYS301
T	THR302
T	GLY317
T	THR323
T	ASP398
T	LYS468
T	ASP470
B	LYS468
T	THR503
U	SER298
U	GLY300
U	LYS301
U	THR302
U	GLY317
U	THR323
U	ASP398
U	LYS468
U	ASP470
B	ASP470
U	THR503
V	SER298
V	GLY300
V	LYS301
V	THR302
V	GLY317
V	THR323
V	ASP398
V	LYS468
V	ASP470
A	LYS301
B	THR503
V	THR503
W	SER298
W	GLY300
W	LYS301
W	THR302
W	GLY317
W	THR323
W	ASP398
W	LYS468
W	ASP470
b	SER298
W	THR503
X	SER298
X	GLY300
X	LYS301
X	THR302
X	GLY317
X	THR323
X	ASP398
X	LYS468
X	ASP470
b	GLY300
X	THR503
Y	SER298
Y	GLY300
Y	LYS301
Y	THR302
Y	GLY317
Y	THR323
Y	ASP398
Y	LYS468
Y	ASP470
b	LYS301
Y	THR503
Z	SER298
Z	GLY300
Z	LYS301
Z	THR302
Z	GLY317
Z	THR323
Z	ASP398
Z	LYS468
Z	ASP470
b	THR302
Z	THR503
b	GLY317
b	THR323
b	ASP398
b	LYS468
b	ASP470
A	THR302
b	THR503
C	SER298
C	GLY300
C	LYS301
C	THR302
C	GLY317
C	THR323
C	ASP398
C	LYS468
C	ASP470
A	GLY317
C	THR503
c	SER298
c	GLY300
c	LYS301
c	THR302
c	GLY317
c	THR323
c	ASP398
c	LYS468
c	ASP470
A	THR323
c	THR503
D	SER298
D	GLY300
D	LYS301
D	THR302
D	GLY317
D	THR323
D	ASP398
D	LYS468
D	ASP470
A	ASP398
D	THR503
d	SER298
d	GLY300
d	LYS301
d	THR302
d	GLY317
d	THR323
d	ASP398
d	LYS468
d	ASP470
A	LYS468
d	THR503
E	SER298
E	GLY300
E	LYS301
E	THR302
E	GLY317
E	THR323
E	ASP398
E	LYS468
E	ASP470
A	ASP470
E	THR503
e	SER298
e	GLY300
e	LYS301
e	THR302
e	GLY317
e	THR323
e	ASP398
e	LYS468
e	ASP470

---

site_id	SWS_FT_FI6
Number of Residues	34
Details	BINDING: BINDING => ECO:0000305|PubMed:32379273, ECO:0000305|PubMed:37612506, ECO:0007744|PDB:6JTG, ECO:0007744|PDB:8EEW

Chain	Residue	Details
A	SER303
e	SER303
F	SER303
f	SER303
G	SER303
g	SER303
H	SER303
h	SER303
I	SER303
J	SER303
K	SER303
a	SER303
L	SER303
M	SER303
N	SER303
O	SER303
P	SER303
Q	SER303
R	SER303
S	SER303
T	SER303
U	SER303
B	SER303
V	SER303
W	SER303
X	SER303
Y	SER303
Z	SER303
b	SER303
C	SER303
c	SER303
D	SER303
d	SER303
E	SER303

---

site_id	SWS_FT_FI7
Number of Residues	68
Details	BINDING: BINDING => ECO:0000305|PubMed:37612506, ECO:0007744|PDB:8EEW

Chain	Residue	Details
A	GLY506
C	ASN507
c	GLY506
c	ASN507
D	GLY506
D	ASN507
d	GLY506
d	ASN507
E	GLY506
E	ASN507
e	GLY506
A	ASN507
e	ASN507
F	GLY506
F	ASN507
f	GLY506
f	ASN507
G	GLY506
G	ASN507
g	GLY506
g	ASN507
H	GLY506
a	GLY506
H	ASN507
h	GLY506
h	ASN507
I	GLY506
I	ASN507
J	GLY506
J	ASN507
K	GLY506
K	ASN507
L	GLY506
a	ASN507
L	ASN507
M	GLY506
M	ASN507
N	GLY506
N	ASN507
O	GLY506
O	ASN507
P	GLY506
P	ASN507
Q	GLY506
B	GLY506
Q	ASN507
R	GLY506
R	ASN507
S	GLY506
S	ASN507
T	GLY506
T	ASN507
U	GLY506
U	ASN507
V	GLY506
B	ASN507
V	ASN507
W	GLY506
W	ASN507
X	GLY506
X	ASN507
Y	GLY506
Y	ASN507
Z	GLY506
Z	ASN507
b	GLY506
b	ASN507
C	GLY506

---

site_id	SWS_FT_FI8
Number of Residues	34
Details	SITE: Cleavage at site S1 => ECO:0000250|UniProtKB:Q2TA68

Chain	Residue	Details
A	ARG194
e	ARG194
F	ARG194
f	ARG194
G	ARG194
g	ARG194
H	ARG194
h	ARG194
I	ARG194
J	ARG194
K	ARG194
a	ARG194
L	ARG194
M	ARG194
N	ARG194
O	ARG194
P	ARG194
Q	ARG194
R	ARG194
S	ARG194
T	ARG194
U	ARG194
B	ARG194
V	ARG194
W	ARG194
X	ARG194
Y	ARG194
Z	ARG194
b	ARG194
C	ARG194
c	ARG194
D	ARG194
d	ARG194
E	ARG194

---

site_id	SWS_FT_FI9
Number of Residues	34
Details	MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861

Chain	Residue	Details
A	LYS228
e	LYS228
F	LYS228
f	LYS228
G	LYS228
g	LYS228
H	LYS228
h	LYS228
I	LYS228
J	LYS228
K	LYS228
a	LYS228
L	LYS228
M	LYS228
N	LYS228
O	LYS228
P	LYS228
Q	LYS228
R	LYS228
S	LYS228
T	LYS228
U	LYS228
B	LYS228
V	LYS228
W	LYS228
X	LYS228
Y	LYS228
Z	LYS228
b	LYS228
C	LYS228
c	LYS228
D	LYS228
d	LYS228
E	LYS228

---