8CR7
Crystal structure of recombinant LasB from Pseudomonas aeruginosa PA7
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004175 | molecular_function | endopeptidase activity |
| A | 0004222 | molecular_function | metalloendopeptidase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0006508 | biological_process | proteolysis |
| A | 0008237 | molecular_function | metallopeptidase activity |
| A | 0015628 | biological_process | protein secretion by the type II secretion system |
| A | 0043952 | biological_process | protein transport by the Sec complex |
| A | 0044010 | biological_process | single-species biofilm formation |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0071978 | biological_process | bacterial-type flagellum-dependent swarming motility |
| B | 0004175 | molecular_function | endopeptidase activity |
| B | 0004222 | molecular_function | metalloendopeptidase activity |
| B | 0005576 | cellular_component | extracellular region |
| B | 0006508 | biological_process | proteolysis |
| B | 0008237 | molecular_function | metallopeptidase activity |
| B | 0015628 | biological_process | protein secretion by the type II secretion system |
| B | 0043952 | biological_process | protein transport by the Sec complex |
| B | 0044010 | biological_process | single-species biofilm formation |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0071978 | biological_process | bacterial-type flagellum-dependent swarming motility |
Functional Information from PROSITE/UniProt
| site_id | PS00142 |
| Number of Residues | 10 |
| Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. VAAHEVSHGF |
| Chain | Residue | Details |
| A | VAL137-PHE146 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: ACT_SITE => ECO:0000305|PubMed:1899664 |
| Chain | Residue | Details |
| A | GLU141 | |
| B | GLU141 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton donor => ECO:0000305|PubMed:1899664 |
| Chain | Residue | Details |
| A | HIS223 | |
| B | HIS223 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 16 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:1899664, ECO:0000269|Ref.16, ECO:0000269|Ref.17 |
| Chain | Residue | Details |
| A | ASP136 | |
| B | HIS140 | |
| B | HIS144 | |
| B | GLU164 | |
| B | GLU172 | |
| B | GLU175 | |
| B | ASP183 | |
| B | LEU185 | |
| A | HIS140 | |
| A | HIS144 | |
| A | GLU164 | |
| A | GLU172 | |
| A | GLU175 | |
| A | ASP183 | |
| A | LEU185 | |
| B | ASP136 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by autolysis => ECO:0000269|PubMed:1744034 |
| Chain | Residue | Details |
| A | HIS0 | |
| B | HIS0 |
