8CQM

Broad-range phospholipase C from Listeria monocytogenes

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004629	molecular_function	phospholipase C activity
A	0004767	molecular_function	sphingomyelin phosphodiesterase activity
A	0005576	cellular_component	extracellular region
A	0008270	molecular_function	zinc ion binding
A	0016787	molecular_function	hydrolase activity
A	0016788	molecular_function	hydrolase activity, acting on ester bonds
A	0034480	molecular_function	phosphatidylcholine phospholipase C activity
A	0046872	molecular_function	metal ion binding
B	0004629	molecular_function	phospholipase C activity
B	0004767	molecular_function	sphingomyelin phosphodiesterase activity
B	0005576	cellular_component	extracellular region
B	0008270	molecular_function	zinc ion binding
B	0016787	molecular_function	hydrolase activity
B	0016788	molecular_function	hydrolase activity, acting on ester bonds
B	0034480	molecular_function	phosphatidylcholine phospholipase C activity
B	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS00384
Number of Residues	14
Details	PROKAR_ZN_DEPEND_PLPC_1 Prokaryotic zinc-dependent phospholipase C signature. HYyTDISqPmHAnN

Chain	Residue	Details
A	HIS118-ASN131

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00678

Chain	Residue	Details
A	TRP1
B	HIS128
B	HIS142
B	GLU146
A	HIS14
A	ASP55
A	HIS128
A	HIS142
A	GLU146
B	TRP1
B	HIS14
B	ASP55

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site_id	SWS_FT_FI2
Number of Residues	6
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00678, ECO:0000269|PubMed:37838694, ECO:0007744|PDB:8CQM

Chain	Residue	Details
A	HIS69
A	HIS118
A	ASP122
B	HIS69
B	HIS118
B	ASP122

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