8CQC
Cryo-EM structure of pentameric proteorhodopsin A18L mutant
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005216 | molecular_function | monoatomic ion channel activity |
| A | 0006811 | biological_process | monoatomic ion transport |
| A | 0010461 | molecular_function | light-activated monoatomic ion channel activity |
| A | 0016020 | cellular_component | membrane |
| B | 0005216 | molecular_function | monoatomic ion channel activity |
| B | 0006811 | biological_process | monoatomic ion transport |
| B | 0010461 | molecular_function | light-activated monoatomic ion channel activity |
| B | 0016020 | cellular_component | membrane |
| C | 0005216 | molecular_function | monoatomic ion channel activity |
| C | 0006811 | biological_process | monoatomic ion transport |
| C | 0010461 | molecular_function | light-activated monoatomic ion channel activity |
| C | 0016020 | cellular_component | membrane |
| D | 0005216 | molecular_function | monoatomic ion channel activity |
| D | 0006811 | biological_process | monoatomic ion transport |
| D | 0010461 | molecular_function | light-activated monoatomic ion channel activity |
| D | 0016020 | cellular_component | membrane |
| E | 0005216 | molecular_function | monoatomic ion channel activity |
| E | 0006811 | biological_process | monoatomic ion transport |
| E | 0010461 | molecular_function | light-activated monoatomic ion channel activity |
| E | 0016020 | cellular_component | membrane |
Functional Information from PROSITE/UniProt
| site_id | PS00950 |
| Number of Residues | 13 |
| Details | BACTERIAL_OPSIN_1 Bacterial rhodopsins signature 1. RYiDWlLTVPLLI |
| Chain | Residue | Details |
| A | ARG95-ILE107 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 930 |
| Details | Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"34226545","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 40 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"34226545","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 20 |
| Details | Topological domain: {"description":"Extracellular","evidences":[{"source":"PubMed","id":"34226545","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 5 |
| Details | Site: {"description":"Primary proton acceptor","evidences":[{"source":"PIRSR","id":"PIRSR038142-1","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"34226545","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 5 |
| Details | Site: {"description":"Responsible for spectral tuning","evidences":[{"source":"PIRSR","id":"PIRSR038142-1","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 5 |
| Details | Site: {"description":"Primary proton donor","evidences":[{"source":"PIRSR","id":"PIRSR038142-1","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"34226545","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 5 |
| Details | Site: {"description":"Proton release group","evidences":[{"source":"PubMed","id":"34226545","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 5 |
| Details | Modified residue: {"description":"N6-(retinylidene)lysine","evidences":[{"source":"PubMed","id":"34226545","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7B03","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
