8CO4

Crystal structure of apo S-nitrosoglutathione reductase from Arabidopsis thalina

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004022	molecular_function	alcohol dehydrogenase (NAD+) activity
A	0004024	molecular_function	alcohol dehydrogenase (NAD+) activity, zinc-dependent
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0008270	molecular_function	zinc ion binding
A	0016491	molecular_function	oxidoreductase activity
A	0046294	biological_process	formaldehyde catabolic process
A	0046872	molecular_function	metal ion binding
A	0051903	molecular_function	S-(hydroxymethyl)glutathione dehydrogenase (NAD(P)+) activity
A	0106321	molecular_function	S-(hydroxymethyl)glutathione dehydrogenase (NADP+) activity
A	0106322	molecular_function	S-(hydroxymethyl)glutathione dehydrogenase (NAD+) activity
B	0004022	molecular_function	alcohol dehydrogenase (NAD+) activity
B	0004024	molecular_function	alcohol dehydrogenase (NAD+) activity, zinc-dependent
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0008270	molecular_function	zinc ion binding
B	0016491	molecular_function	oxidoreductase activity
B	0046294	biological_process	formaldehyde catabolic process
B	0046872	molecular_function	metal ion binding
B	0051903	molecular_function	S-(hydroxymethyl)glutathione dehydrogenase (NAD(P)+) activity
B	0106321	molecular_function	S-(hydroxymethyl)glutathione dehydrogenase (NADP+) activity
B	0106322	molecular_function	S-(hydroxymethyl)glutathione dehydrogenase (NAD+) activity
C	0004022	molecular_function	alcohol dehydrogenase (NAD+) activity
C	0004024	molecular_function	alcohol dehydrogenase (NAD+) activity, zinc-dependent
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0008270	molecular_function	zinc ion binding
C	0016491	molecular_function	oxidoreductase activity
C	0046294	biological_process	formaldehyde catabolic process
C	0046872	molecular_function	metal ion binding
C	0051903	molecular_function	S-(hydroxymethyl)glutathione dehydrogenase (NAD(P)+) activity
C	0106321	molecular_function	S-(hydroxymethyl)glutathione dehydrogenase (NADP+) activity
C	0106322	molecular_function	S-(hydroxymethyl)glutathione dehydrogenase (NAD+) activity
D	0004022	molecular_function	alcohol dehydrogenase (NAD+) activity
D	0004024	molecular_function	alcohol dehydrogenase (NAD+) activity, zinc-dependent
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0008270	molecular_function	zinc ion binding
D	0016491	molecular_function	oxidoreductase activity
D	0046294	biological_process	formaldehyde catabolic process
D	0046872	molecular_function	metal ion binding
D	0051903	molecular_function	S-(hydroxymethyl)glutathione dehydrogenase (NAD(P)+) activity
D	0106321	molecular_function	S-(hydroxymethyl)glutathione dehydrogenase (NADP+) activity
D	0106322	molecular_function	S-(hydroxymethyl)glutathione dehydrogenase (NAD+) activity

Functional Information from PROSITE/UniProt

site_id	PS00059
Number of Residues	15
Details	ADH_ZINC Zinc-containing alcohol dehydrogenases signature. GHEaAGIvesvGegV

Chain	Residue	Details
A	GLY68-VAL82

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	56
Details	BINDING: BINDING => ECO:0000269|Ref.13, ECO:0007744|PDB:3UKO, ECO:0007744|PDB:4GL4, ECO:0007744|PDB:4JJI, ECO:0007744|PDB:4L0Q

Chain	Residue	Details
A	CYS47
A	HIS48
A	HIS69
A	GLU70
A	CYS99
A	CYS102
A	CYS105
A	CYS113
A	CYS177
A	GLY202
A	ASP226
A	ILE272
A	VAL295
A	THR320
B	CYS47
B	HIS48
B	HIS69
B	GLU70
B	CYS99
B	CYS102
B	CYS105
B	CYS113
B	CYS177
B	GLY202
B	ASP226
B	ILE272
B	VAL295
B	THR320
C	CYS47
C	HIS48
C	HIS69
C	GLU70
C	CYS99
C	CYS102
C	CYS105
C	CYS113
C	CYS177
C	GLY202
C	ASP226
C	ILE272
C	VAL295
C	THR320
D	CYS47
D	HIS48
D	HIS69
D	GLU70
D	CYS99
D	CYS102
D	CYS105
D	CYS113
D	CYS177
D	GLY202
D	ASP226
D	ILE272
D	VAL295
D	THR320

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site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P06525

Chain	Residue	Details
A	THR49
B	THR49
C	THR49
D	THR49

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site_id	SWS_FT_FI3
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269|Ref.13, ECO:0007744|PDB:3UKO, ECO:0007744|PDB:4JJI, ECO:0007744|PDB:4L0Q

Chain	Residue	Details
A	LYS231
A	ARG372
B	LYS231
B	ARG372
C	LYS231
C	ARG372
D	LYS231
D	ARG372

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site_id	SWS_FT_FI4
Number of Residues	4
Details	MOD_RES: N-acetylalanine => ECO:0007744|PubMed:22223895

Chain	Residue	Details
A	ALA2
B	ALA2
C	ALA2
D	ALA2

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