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8CM8

Galectin-8 N-terminal carbohydrate recognition domain in complex with 4-(bromophenyl)phthalazinone D-galactal ligand

Functional Information from GO Data
ChainGOidnamespacecontents
A0005178molecular_functionintegrin binding
A0005515molecular_functionprotein binding
A0005615cellular_componentextracellular space
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0006914biological_processautophagy
A0016020cellular_componentmembrane
A0030246molecular_functioncarbohydrate binding
A0031410cellular_componentcytoplasmic vesicle
A0098586biological_processcellular response to virus
A0098792biological_processxenophagy
A1904977biological_processlymphatic endothelial cell migration
B0005178molecular_functionintegrin binding
B0005515molecular_functionprotein binding
B0005615cellular_componentextracellular space
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0006914biological_processautophagy
B0016020cellular_componentmembrane
B0030246molecular_functioncarbohydrate binding
B0031410cellular_componentcytoplasmic vesicle
B0098586biological_processcellular response to virus
B0098792biological_processxenophagy
B1904977biological_processlymphatic endothelial cell migration
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues6
DetailsBINDING: BINDING => ECO:0000269|PubMed:21288902
ChainResidueDetails
AARG69
AASN79
AGLU89
BARG69
BASN79
BGLU89

site_idSWS_FT_FI2
Number of Residues2
DetailsBINDING: BINDING => ECO:0000250
ChainResidueDetails
ATRP249
BTRP249

site_idSWS_FT_FI3
Number of Residues2
DetailsSITE: Critical for binding to sialylated and sulfated oligosaccharides => ECO:0000269|PubMed:21288902
ChainResidueDetails
AARG59
BARG59

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PDB entries from 2024-05-29

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