8CG4
The organise full-length structure of the fungal non-reducing polyketide synthase (NR-PKS) PksA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004312 | molecular_function | fatty acid synthase activity |
| A | 0006633 | biological_process | fatty acid biosynthetic process |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0031177 | molecular_function | phosphopantetheine binding |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0044550 | biological_process | secondary metabolite biosynthetic process |
| A | 0045122 | biological_process | aflatoxin biosynthetic process |
| A | 0102973 | molecular_function | norsolorinate anthrone synthase activity |
| B | 0004312 | molecular_function | fatty acid synthase activity |
| B | 0006633 | biological_process | fatty acid biosynthetic process |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016746 | molecular_function | acyltransferase activity |
| B | 0031177 | molecular_function | phosphopantetheine binding |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0044550 | biological_process | secondary metabolite biosynthetic process |
| B | 0045122 | biological_process | aflatoxin biosynthetic process |
| B | 0102973 | molecular_function | norsolorinate anthrone synthase activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | ACT_SITE: For beta-ketoacyl synthase activity => ECO:0000255|PROSITE-ProRule:PRU01348 |
| Chain | Residue | Details |
| A | CYS543 | |
| A | HIS678 | |
| A | HIS721 | |
| B | CYS543 | |
| B | HIS678 | |
| B | HIS721 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | ACT_SITE: For acyl/malonyl transferase activity => ECO:0000250 |
| Chain | Residue | Details |
| A | SER993 | |
| B | SER993 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton acceptor; for dehydratase activity => ECO:0000255|PROSITE-ProRule:PRU01363 |
| Chain | Residue | Details |
| A | HIS1345 | |
| B | HIS1345 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton donor; for dehydratase activity => ECO:0000255|PROSITE-ProRule:PRU01363 |
| Chain | Residue | Details |
| A | ASP1543 | |
| B | ASP1543 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | ACT_SITE: For thioesterase activity => ECO:0000269|PubMed:20332208 |
| Chain | Residue | Details |
| A | SER1937 | |
| B | SER1937 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | MOD_RES: O-(pantetheine 4'-phosphoryl)serine => ECO:0000255|PROSITE-ProRule:PRU00258, ECO:0000269|PubMed:20136099 |
| Chain | Residue | Details |
| A | SER1746 | |
| B | SER1746 |
