8CEO

Yeast RNA polymerase II transcription pre-initiation complex with core Mediator and the +1 nucleosome

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
0	0000019	biological_process	regulation of mitotic recombination
0	0000112	cellular_component	nucleotide-excision repair factor 3 complex
0	0000439	cellular_component	transcription factor TFIIH core complex
0	0003676	molecular_function	nucleic acid binding
0	0003677	molecular_function	DNA binding
0	0003678	molecular_function	DNA helicase activity
0	0003684	molecular_function	damaged DNA binding
0	0004386	molecular_function	helicase activity
0	0005515	molecular_function	protein binding
0	0005524	molecular_function	ATP binding
0	0005634	cellular_component	nucleus
0	0005675	cellular_component	transcription factor TFIIH holo complex
0	0005829	cellular_component	cytosol
0	0006139	biological_process	nucleobase-containing compound metabolic process
0	0006281	biological_process	DNA repair
0	0006289	biological_process	nucleotide-excision repair
0	0006366	biological_process	transcription by RNA polymerase II
0	0006367	biological_process	transcription initiation at RNA polymerase II promoter
0	0006974	biological_process	DNA damage response
0	0008094	molecular_function	ATP-dependent activity, acting on DNA
0	0016787	molecular_function	hydrolase activity
0	0016818	molecular_function	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
0	0016853	molecular_function	isomerase activity
0	0016887	molecular_function	ATP hydrolysis activity
0	0032508	biological_process	DNA duplex unwinding
0	0032991	cellular_component	protein-containing complex
0	0043139	molecular_function	5'-3' DNA helicase activity
0	0045951	biological_process	positive regulation of mitotic recombination
0	0046872	molecular_function	metal ion binding
0	0051539	molecular_function	4 iron, 4 sulfur cluster binding
1	0000112	cellular_component	nucleotide-excision repair factor 3 complex
1	0000439	cellular_component	transcription factor TFIIH core complex
1	0005515	molecular_function	protein binding
1	0005634	cellular_component	nucleus
1	0005675	cellular_component	transcription factor TFIIH holo complex
1	0005829	cellular_component	cytosol
1	0006281	biological_process	DNA repair
1	0006289	biological_process	nucleotide-excision repair
1	0006351	biological_process	DNA-templated transcription
1	0006360	biological_process	transcription by RNA polymerase I
1	0006366	biological_process	transcription by RNA polymerase II
1	0006367	biological_process	transcription initiation at RNA polymerase II promoter
1	0010314	molecular_function	phosphatidylinositol-5-phosphate binding
1	0032266	molecular_function	phosphatidylinositol-3-phosphate binding
2	0000112	cellular_component	nucleotide-excision repair factor 3 complex
2	0000439	cellular_component	transcription factor TFIIH core complex
2	0001671	molecular_function	ATPase activator activity
2	0003690	molecular_function	double-stranded DNA binding
2	0005515	molecular_function	protein binding
2	0005634	cellular_component	nucleus
2	0005675	cellular_component	transcription factor TFIIH holo complex
2	0006281	biological_process	DNA repair
2	0006289	biological_process	nucleotide-excision repair
2	0006366	biological_process	transcription by RNA polymerase II
2	0006367	biological_process	transcription initiation at RNA polymerase II promoter
3	0000993	molecular_function	RNA polymerase II complex binding
3	0005634	cellular_component	nucleus
3	0005675	cellular_component	transcription factor TFIIH holo complex
3	0006281	biological_process	DNA repair
3	0006289	biological_process	nucleotide-excision repair
3	0006357	biological_process	regulation of transcription by RNA polymerase II
3	0006366	biological_process	transcription by RNA polymerase II
3	0006367	biological_process	transcription initiation at RNA polymerase II promoter
3	0008270	molecular_function	zinc ion binding
3	0045737	biological_process	positive regulation of cyclin-dependent protein serine/threonine kinase activity
3	0046872	molecular_function	metal ion binding
3	0061575	molecular_function	cyclin-dependent protein serine/threonine kinase activator activity
3	0070985	cellular_component	transcription factor TFIIK complex
4	0000112	cellular_component	nucleotide-excision repair factor 3 complex
4	0000439	cellular_component	transcription factor TFIIH core complex
4	0005634	cellular_component	nucleus
4	0005675	cellular_component	transcription factor TFIIH holo complex
4	0006281	biological_process	DNA repair
4	0006289	biological_process	nucleotide-excision repair
4	0006355	biological_process	regulation of DNA-templated transcription
4	0006366	biological_process	transcription by RNA polymerase II
4	0006367	biological_process	transcription initiation at RNA polymerase II promoter
4	0008270	molecular_function	zinc ion binding
4	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
4	0046872	molecular_function	metal ion binding
5	0000439	cellular_component	transcription factor TFIIH core complex
5	0000993	molecular_function	RNA polymerase II complex binding
5	0005515	molecular_function	protein binding
5	0005634	cellular_component	nucleus
5	0005675	cellular_component	transcription factor TFIIH holo complex
5	0005829	cellular_component	cytosol
5	0006281	biological_process	DNA repair
5	0006289	biological_process	nucleotide-excision repair
5	0006294	biological_process	nucleotide-excision repair, preincision complex assembly
5	0006366	biological_process	transcription by RNA polymerase II
5	0006367	biological_process	transcription initiation at RNA polymerase II promoter
6	0000112	cellular_component	nucleotide-excision repair factor 3 complex
6	0000439	cellular_component	transcription factor TFIIH core complex
6	0005634	cellular_component	nucleus
6	0005675	cellular_component	transcription factor TFIIH holo complex
6	0006281	biological_process	DNA repair
6	0006289	biological_process	nucleotide-excision repair
6	0006351	biological_process	DNA-templated transcription
6	0006357	biological_process	regulation of transcription by RNA polymerase II
6	0006366	biological_process	transcription by RNA polymerase II
6	0006367	biological_process	transcription initiation at RNA polymerase II promoter
6	0008270	molecular_function	zinc ion binding
6	0046872	molecular_function	metal ion binding
6	0061630	molecular_function	ubiquitin protein ligase activity
7	0000019	biological_process	regulation of mitotic recombination
7	0000112	cellular_component	nucleotide-excision repair factor 3 complex
7	0000439	cellular_component	transcription factor TFIIH core complex
7	0001111	biological_process	RNA polymerase II promoter clearance
7	0001113	biological_process	transcription open complex formation at RNA polymerase II promoter
7	0001174	biological_process	transcriptional start site selection at RNA polymerase II promoter
7	0003677	molecular_function	DNA binding
7	0003678	molecular_function	DNA helicase activity
7	0004386	molecular_function	helicase activity
7	0005524	molecular_function	ATP binding
7	0005634	cellular_component	nucleus
7	0005675	cellular_component	transcription factor TFIIH holo complex
7	0005829	cellular_component	cytosol
7	0006281	biological_process	DNA repair
7	0006289	biological_process	nucleotide-excision repair
7	0006366	biological_process	transcription by RNA polymerase II
7	0006367	biological_process	transcription initiation at RNA polymerase II promoter
7	0015616	molecular_function	DNA translocase activity
7	0016787	molecular_function	hydrolase activity
7	0016853	molecular_function	isomerase activity
7	0016887	molecular_function	ATP hydrolysis activity
7	0016973	biological_process	poly(A)+ mRNA export from nucleus
7	0032508	biological_process	DNA duplex unwinding
7	0043138	molecular_function	3'-5' DNA helicase activity
7	0097550	cellular_component	transcription preinitiation complex
a	0003712	molecular_function	transcription coregulator activity
a	0003713	molecular_function	transcription coactivator activity
a	0005515	molecular_function	protein binding
a	0005634	cellular_component	nucleus
a	0006357	biological_process	regulation of transcription by RNA polymerase II
a	0016592	cellular_component	mediator complex
a	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
a	0045944	biological_process	positive regulation of transcription by RNA polymerase II
a	0051123	biological_process	RNA polymerase II preinitiation complex assembly
a	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
a	0070847	cellular_component	core mediator complex
A	0000428	cellular_component	DNA-directed RNA polymerase complex
A	0001055	molecular_function	RNA polymerase II activity
A	0001172	biological_process	RNA-templated transcription
A	0003677	molecular_function	DNA binding
A	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
A	0003968	molecular_function	RNA-dependent RNA polymerase activity
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005665	cellular_component	RNA polymerase II, core complex
A	0005739	cellular_component	mitochondrion
A	0006351	biological_process	DNA-templated transcription
A	0006366	biological_process	transcription by RNA polymerase II
A	0006367	biological_process	transcription initiation at RNA polymerase II promoter
A	0006368	biological_process	transcription elongation by RNA polymerase II
A	0008270	molecular_function	zinc ion binding
A	0010494	cellular_component	cytoplasmic stress granule
A	0016779	molecular_function	nucleotidyltransferase activity
A	0019985	biological_process	translesion synthesis
A	0034062	molecular_function	5'-3' RNA polymerase activity
A	0046872	molecular_function	metal ion binding
b	0000122	biological_process	negative regulation of transcription by RNA polymerase II
b	0000978	molecular_function	RNA polymerase II cis-regulatory region sequence-specific DNA binding
b	0003677	molecular_function	DNA binding
b	0003712	molecular_function	transcription coregulator activity
b	0003714	molecular_function	transcription corepressor activity
b	0005515	molecular_function	protein binding
b	0005634	cellular_component	nucleus
b	0006357	biological_process	regulation of transcription by RNA polymerase II
b	0016592	cellular_component	mediator complex
b	0017025	molecular_function	TBP-class protein binding
b	0030674	molecular_function	protein-macromolecule adaptor activity
b	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
b	0045944	biological_process	positive regulation of transcription by RNA polymerase II
b	0051123	biological_process	RNA polymerase II preinitiation complex assembly
b	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
b	0070847	cellular_component	core mediator complex
B	0000428	cellular_component	DNA-directed RNA polymerase complex
B	0001055	molecular_function	RNA polymerase II activity
B	0001172	biological_process	RNA-templated transcription
B	0003677	molecular_function	DNA binding
B	0003729	molecular_function	mRNA binding
B	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
B	0003968	molecular_function	RNA-dependent RNA polymerase activity
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005665	cellular_component	RNA polymerase II, core complex
B	0005739	cellular_component	mitochondrion
B	0006351	biological_process	DNA-templated transcription
B	0006366	biological_process	transcription by RNA polymerase II
B	0006367	biological_process	transcription initiation at RNA polymerase II promoter
B	0006368	biological_process	transcription elongation by RNA polymerase II
B	0008270	molecular_function	zinc ion binding
B	0010494	cellular_component	cytoplasmic stress granule
B	0016779	molecular_function	nucleotidyltransferase activity
B	0032549	molecular_function	ribonucleoside binding
B	0034062	molecular_function	5'-3' RNA polymerase activity
B	0046872	molecular_function	metal ion binding
c	0000122	biological_process	negative regulation of transcription by RNA polymerase II
c	0001097	molecular_function	TFIIH-class transcription factor complex binding
c	0003712	molecular_function	transcription coregulator activity
c	0003713	molecular_function	transcription coactivator activity
c	0005515	molecular_function	protein binding
c	0005634	cellular_component	nucleus
c	0006357	biological_process	regulation of transcription by RNA polymerase II
c	0016592	cellular_component	mediator complex
c	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
c	0045944	biological_process	positive regulation of transcription by RNA polymerase II
c	0051123	biological_process	RNA polymerase II preinitiation complex assembly
c	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
c	0070847	cellular_component	core mediator complex
C	0000428	cellular_component	DNA-directed RNA polymerase complex
C	0001055	molecular_function	RNA polymerase II activity
C	0001172	biological_process	RNA-templated transcription
C	0003677	molecular_function	DNA binding
C	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
C	0003968	molecular_function	RNA-dependent RNA polymerase activity
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005665	cellular_component	RNA polymerase II, core complex
C	0006351	biological_process	DNA-templated transcription
C	0006366	biological_process	transcription by RNA polymerase II
C	0006367	biological_process	transcription initiation at RNA polymerase II promoter
C	0006368	biological_process	transcription elongation by RNA polymerase II
C	0006369	biological_process	termination of RNA polymerase II transcription
C	0008270	molecular_function	zinc ion binding
C	0046872	molecular_function	metal ion binding
C	0046983	molecular_function	protein dimerization activity
C	0055029	cellular_component	nuclear DNA-directed RNA polymerase complex
d	0000979	molecular_function	RNA polymerase II core promoter sequence-specific DNA binding
d	0001139	molecular_function	RNA polymerase II complex recruiting activity
d	0003712	molecular_function	transcription coregulator activity
d	0005515	molecular_function	protein binding
d	0005634	cellular_component	nucleus
d	0006357	biological_process	regulation of transcription by RNA polymerase II
d	0006367	biological_process	transcription initiation at RNA polymerase II promoter
d	0016592	cellular_component	mediator complex
d	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
d	0034605	biological_process	cellular response to heat
d	0045944	biological_process	positive regulation of transcription by RNA polymerase II
d	0051123	biological_process	RNA polymerase II preinitiation complex assembly
d	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
d	0070847	cellular_component	core mediator complex
d	0140297	molecular_function	DNA-binding transcription factor binding
D	0000166	molecular_function	nucleotide binding
D	0000288	biological_process	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
D	0000428	cellular_component	DNA-directed RNA polymerase complex
D	0000932	cellular_component	P-body
D	0001172	biological_process	RNA-templated transcription
D	0003697	molecular_function	single-stranded DNA binding
D	0003727	molecular_function	single-stranded RNA binding
D	0003968	molecular_function	RNA-dependent RNA polymerase activity
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005665	cellular_component	RNA polymerase II, core complex
D	0005737	cellular_component	cytoplasm
D	0006352	biological_process	DNA-templated transcription initiation
D	0006366	biological_process	transcription by RNA polymerase II
D	0006367	biological_process	transcription initiation at RNA polymerase II promoter
D	0006368	biological_process	transcription elongation by RNA polymerase II
D	0006397	biological_process	mRNA processing
D	0030880	cellular_component	RNA polymerase complex
D	0031369	molecular_function	translation initiation factor binding
D	0044237	biological_process	cellular metabolic process
D	0045948	biological_process	positive regulation of translational initiation
D	1990328	cellular_component	RPB4-RPB7 complex
e	0000979	molecular_function	RNA polymerase II core promoter sequence-specific DNA binding
e	0001113	biological_process	transcription open complex formation at RNA polymerase II promoter
e	0003712	molecular_function	transcription coregulator activity
e	0003713	molecular_function	transcription coactivator activity
e	0005515	molecular_function	protein binding
e	0005634	cellular_component	nucleus
e	0006357	biological_process	regulation of transcription by RNA polymerase II
e	0006369	biological_process	termination of RNA polymerase II transcription
e	0016592	cellular_component	mediator complex
e	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
e	0034605	biological_process	cellular response to heat
e	0045944	biological_process	positive regulation of transcription by RNA polymerase II
e	0051123	biological_process	RNA polymerase II preinitiation complex assembly
e	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
e	0070847	cellular_component	core mediator complex
E	0000428	cellular_component	DNA-directed RNA polymerase complex
E	0001054	molecular_function	RNA polymerase I activity
E	0001055	molecular_function	RNA polymerase II activity
E	0001056	molecular_function	RNA polymerase III activity
E	0001172	biological_process	RNA-templated transcription
E	0003677	molecular_function	DNA binding
E	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
E	0003968	molecular_function	RNA-dependent RNA polymerase activity
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005665	cellular_component	RNA polymerase II, core complex
E	0005666	cellular_component	RNA polymerase III complex
E	0005736	cellular_component	RNA polymerase I complex
E	0006351	biological_process	DNA-templated transcription
E	0006360	biological_process	transcription by RNA polymerase I
E	0006361	biological_process	transcription initiation at RNA polymerase I promoter
E	0006362	biological_process	transcription elongation by RNA polymerase I
E	0006363	biological_process	termination of RNA polymerase I transcription
E	0006366	biological_process	transcription by RNA polymerase II
E	0006367	biological_process	transcription initiation at RNA polymerase II promoter
E	0006368	biological_process	transcription elongation by RNA polymerase II
E	0006383	biological_process	transcription by RNA polymerase III
E	0006384	biological_process	transcription initiation at RNA polymerase III promoter
E	0006386	biological_process	termination of RNA polymerase III transcription
E	0042254	biological_process	ribosome biogenesis
E	0042790	biological_process	nucleolar large rRNA transcription by RNA polymerase I
E	0042797	biological_process	tRNA transcription by RNA polymerase III
f	0001094	molecular_function	TFIID-class transcription factor complex binding
f	0003712	molecular_function	transcription coregulator activity
f	0003713	molecular_function	transcription coactivator activity
f	0005515	molecular_function	protein binding
f	0005634	cellular_component	nucleus
f	0006357	biological_process	regulation of transcription by RNA polymerase II
f	0010688	biological_process	negative regulation of ribosomal protein gene transcription by RNA polymerase II
f	0016592	cellular_component	mediator complex
f	0019904	molecular_function	protein domain specific binding
f	0031669	biological_process	cellular response to nutrient levels
f	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
f	0032991	cellular_component	protein-containing complex
f	0045944	biological_process	positive regulation of transcription by RNA polymerase II
f	0051123	biological_process	RNA polymerase II preinitiation complex assembly
f	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
f	0070847	cellular_component	core mediator complex
F	0000428	cellular_component	DNA-directed RNA polymerase complex
F	0001054	molecular_function	RNA polymerase I activity
F	0001055	molecular_function	RNA polymerase II activity
F	0001056	molecular_function	RNA polymerase III activity
F	0001172	biological_process	RNA-templated transcription
F	0003677	molecular_function	DNA binding
F	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
F	0003968	molecular_function	RNA-dependent RNA polymerase activity
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005654	cellular_component	nucleoplasm
F	0005665	cellular_component	RNA polymerase II, core complex
F	0005666	cellular_component	RNA polymerase III complex
F	0005736	cellular_component	RNA polymerase I complex
F	0005737	cellular_component	cytoplasm
F	0006351	biological_process	DNA-templated transcription
F	0006360	biological_process	transcription by RNA polymerase I
F	0006361	biological_process	transcription initiation at RNA polymerase I promoter
F	0006362	biological_process	transcription elongation by RNA polymerase I
F	0006363	biological_process	termination of RNA polymerase I transcription
F	0006366	biological_process	transcription by RNA polymerase II
F	0006367	biological_process	transcription initiation at RNA polymerase II promoter
F	0006368	biological_process	transcription elongation by RNA polymerase II
F	0006383	biological_process	transcription by RNA polymerase III
F	0006384	biological_process	transcription initiation at RNA polymerase III promoter
F	0006386	biological_process	termination of RNA polymerase III transcription
F	0042254	biological_process	ribosome biogenesis
F	0042790	biological_process	nucleolar large rRNA transcription by RNA polymerase I
F	0042797	biological_process	tRNA transcription by RNA polymerase III
g	0003674	molecular_function	molecular_function
g	0003712	molecular_function	transcription coregulator activity
g	0005515	molecular_function	protein binding
g	0005634	cellular_component	nucleus
g	0006357	biological_process	regulation of transcription by RNA polymerase II
g	0016592	cellular_component	mediator complex
g	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
g	0045944	biological_process	positive regulation of transcription by RNA polymerase II
g	0051123	biological_process	RNA polymerase II preinitiation complex assembly
g	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
g	0070847	cellular_component	core mediator complex
G	0000288	biological_process	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
G	0000428	cellular_component	DNA-directed RNA polymerase complex
G	0000932	cellular_component	P-body
G	0000956	biological_process	nuclear-transcribed mRNA catabolic process
G	0001172	biological_process	RNA-templated transcription
G	0003676	molecular_function	nucleic acid binding
G	0003697	molecular_function	single-stranded DNA binding
G	0003727	molecular_function	single-stranded RNA binding
G	0003968	molecular_function	RNA-dependent RNA polymerase activity
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005665	cellular_component	RNA polymerase II, core complex
G	0005737	cellular_component	cytoplasm
G	0006351	biological_process	DNA-templated transcription
G	0006352	biological_process	DNA-templated transcription initiation
G	0006366	biological_process	transcription by RNA polymerase II
G	0006367	biological_process	transcription initiation at RNA polymerase II promoter
G	0006368	biological_process	transcription elongation by RNA polymerase II
G	0031369	molecular_function	translation initiation factor binding
G	0045948	biological_process	positive regulation of translational initiation
G	0055029	cellular_component	nuclear DNA-directed RNA polymerase complex
G	0060213	biological_process	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
G	1990328	cellular_component	RPB4-RPB7 complex
h	0000979	molecular_function	RNA polymerase II core promoter sequence-specific DNA binding
h	0003712	molecular_function	transcription coregulator activity
h	0005515	molecular_function	protein binding
h	0005634	cellular_component	nucleus
h	0006357	biological_process	regulation of transcription by RNA polymerase II
h	0006366	biological_process	transcription by RNA polymerase II
h	0016592	cellular_component	mediator complex
h	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
h	0034605	biological_process	cellular response to heat
h	0051123	biological_process	RNA polymerase II preinitiation complex assembly
h	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
h	0070847	cellular_component	core mediator complex
H	0000428	cellular_component	DNA-directed RNA polymerase complex
H	0001054	molecular_function	RNA polymerase I activity
H	0001055	molecular_function	RNA polymerase II activity
H	0001056	molecular_function	RNA polymerase III activity
H	0001172	biological_process	RNA-templated transcription
H	0003677	molecular_function	DNA binding
H	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
H	0003968	molecular_function	RNA-dependent RNA polymerase activity
H	0005515	molecular_function	protein binding
H	0005634	cellular_component	nucleus
H	0005654	cellular_component	nucleoplasm
H	0005665	cellular_component	RNA polymerase II, core complex
H	0005666	cellular_component	RNA polymerase III complex
H	0005736	cellular_component	RNA polymerase I complex
H	0006351	biological_process	DNA-templated transcription
H	0006360	biological_process	transcription by RNA polymerase I
H	0006361	biological_process	transcription initiation at RNA polymerase I promoter
H	0006362	biological_process	transcription elongation by RNA polymerase I
H	0006363	biological_process	termination of RNA polymerase I transcription
H	0006366	biological_process	transcription by RNA polymerase II
H	0006367	biological_process	transcription initiation at RNA polymerase II promoter
H	0006368	biological_process	transcription elongation by RNA polymerase II
H	0006383	biological_process	transcription by RNA polymerase III
H	0006384	biological_process	transcription initiation at RNA polymerase III promoter
H	0006386	biological_process	termination of RNA polymerase III transcription
H	0042254	biological_process	ribosome biogenesis
H	0042790	biological_process	nucleolar large rRNA transcription by RNA polymerase I
H	0042797	biological_process	tRNA transcription by RNA polymerase III
i	0000122	biological_process	negative regulation of transcription by RNA polymerase II
i	0003712	molecular_function	transcription coregulator activity
i	0003713	molecular_function	transcription coactivator activity
i	0005515	molecular_function	protein binding
i	0005634	cellular_component	nucleus
i	0006357	biological_process	regulation of transcription by RNA polymerase II
i	0016592	cellular_component	mediator complex
i	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
i	0045944	biological_process	positive regulation of transcription by RNA polymerase II
i	0051123	biological_process	RNA polymerase II preinitiation complex assembly
i	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
i	0070847	cellular_component	core mediator complex
I	0000428	cellular_component	DNA-directed RNA polymerase complex
I	0001172	biological_process	RNA-templated transcription
I	0001193	biological_process	maintenance of transcriptional fidelity during transcription elongation by RNA polymerase II
I	0003676	molecular_function	nucleic acid binding
I	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
I	0003968	molecular_function	RNA-dependent RNA polymerase activity
I	0005515	molecular_function	protein binding
I	0005634	cellular_component	nucleus
I	0005654	cellular_component	nucleoplasm
I	0005665	cellular_component	RNA polymerase II, core complex
I	0005730	cellular_component	nucleolus
I	0006281	biological_process	DNA repair
I	0006283	biological_process	transcription-coupled nucleotide-excision repair
I	0006351	biological_process	DNA-templated transcription
I	0006366	biological_process	transcription by RNA polymerase II
I	0006367	biological_process	transcription initiation at RNA polymerase II promoter
I	0006368	biological_process	transcription elongation by RNA polymerase II
I	0008270	molecular_function	zinc ion binding
I	0046872	molecular_function	metal ion binding
I	0055029	cellular_component	nuclear DNA-directed RNA polymerase complex
j	0000122	biological_process	negative regulation of transcription by RNA polymerase II
j	0003712	molecular_function	transcription coregulator activity
j	0003713	molecular_function	transcription coactivator activity
j	0005198	molecular_function	structural molecule activity
j	0005515	molecular_function	protein binding
j	0005634	cellular_component	nucleus
j	0005829	cellular_component	cytosol
j	0006357	biological_process	regulation of transcription by RNA polymerase II
j	0016592	cellular_component	mediator complex
j	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
j	0045944	biological_process	positive regulation of transcription by RNA polymerase II
j	0051123	biological_process	RNA polymerase II preinitiation complex assembly
j	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
j	0070847	cellular_component	core mediator complex
J	0000428	cellular_component	DNA-directed RNA polymerase complex
J	0001054	molecular_function	RNA polymerase I activity
J	0001055	molecular_function	RNA polymerase II activity
J	0001056	molecular_function	RNA polymerase III activity
J	0001172	biological_process	RNA-templated transcription
J	0003677	molecular_function	DNA binding
J	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
J	0003968	molecular_function	RNA-dependent RNA polymerase activity
J	0005515	molecular_function	protein binding
J	0005634	cellular_component	nucleus
J	0005654	cellular_component	nucleoplasm
J	0005665	cellular_component	RNA polymerase II, core complex
J	0005666	cellular_component	RNA polymerase III complex
J	0005730	cellular_component	nucleolus
J	0005736	cellular_component	RNA polymerase I complex
J	0006351	biological_process	DNA-templated transcription
J	0006360	biological_process	transcription by RNA polymerase I
J	0006361	biological_process	transcription initiation at RNA polymerase I promoter
J	0006362	biological_process	transcription elongation by RNA polymerase I
J	0006363	biological_process	termination of RNA polymerase I transcription
J	0006366	biological_process	transcription by RNA polymerase II
J	0006367	biological_process	transcription initiation at RNA polymerase II promoter
J	0006368	biological_process	transcription elongation by RNA polymerase II
J	0006383	biological_process	transcription by RNA polymerase III
J	0006384	biological_process	transcription initiation at RNA polymerase III promoter
J	0006386	biological_process	termination of RNA polymerase III transcription
J	0008270	molecular_function	zinc ion binding
J	0042254	biological_process	ribosome biogenesis
J	0042790	biological_process	nucleolar large rRNA transcription by RNA polymerase I
J	0042797	biological_process	tRNA transcription by RNA polymerase III
J	0046872	molecular_function	metal ion binding
k	0000122	biological_process	negative regulation of transcription by RNA polymerase II
k	0003674	molecular_function	molecular_function
k	0003712	molecular_function	transcription coregulator activity
k	0005515	molecular_function	protein binding
k	0005634	cellular_component	nucleus
k	0006357	biological_process	regulation of transcription by RNA polymerase II
k	0016592	cellular_component	mediator complex
k	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
k	0045944	biological_process	positive regulation of transcription by RNA polymerase II
k	0051123	biological_process	RNA polymerase II preinitiation complex assembly
k	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
k	0070847	cellular_component	core mediator complex
K	0000428	cellular_component	DNA-directed RNA polymerase complex
K	0001055	molecular_function	RNA polymerase II activity
K	0001172	biological_process	RNA-templated transcription
K	0003677	molecular_function	DNA binding
K	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
K	0003968	molecular_function	RNA-dependent RNA polymerase activity
K	0005515	molecular_function	protein binding
K	0005634	cellular_component	nucleus
K	0005665	cellular_component	RNA polymerase II, core complex
K	0006351	biological_process	DNA-templated transcription
K	0006366	biological_process	transcription by RNA polymerase II
K	0006367	biological_process	transcription initiation at RNA polymerase II promoter
K	0006368	biological_process	transcription elongation by RNA polymerase II
K	0006369	biological_process	termination of RNA polymerase II transcription
K	0046983	molecular_function	protein dimerization activity
l	0000122	biological_process	negative regulation of transcription by RNA polymerase II
l	0001093	molecular_function	TFIIB-class transcription factor binding
l	0003712	molecular_function	transcription coregulator activity
l	0005515	molecular_function	protein binding
l	0005634	cellular_component	nucleus
l	0006357	biological_process	regulation of transcription by RNA polymerase II
l	0016592	cellular_component	mediator complex
l	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
l	0032991	cellular_component	protein-containing complex
l	0045944	biological_process	positive regulation of transcription by RNA polymerase II
l	0051123	biological_process	RNA polymerase II preinitiation complex assembly
l	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
l	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
l	0070847	cellular_component	core mediator complex
L	0000428	cellular_component	DNA-directed RNA polymerase complex
L	0001054	molecular_function	RNA polymerase I activity
L	0001055	molecular_function	RNA polymerase II activity
L	0001056	molecular_function	RNA polymerase III activity
L	0001172	biological_process	RNA-templated transcription
L	0003677	molecular_function	DNA binding
L	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
L	0003968	molecular_function	RNA-dependent RNA polymerase activity
L	0005634	cellular_component	nucleus
L	0005654	cellular_component	nucleoplasm
L	0005665	cellular_component	RNA polymerase II, core complex
L	0005666	cellular_component	RNA polymerase III complex
L	0005730	cellular_component	nucleolus
L	0005736	cellular_component	RNA polymerase I complex
L	0005737	cellular_component	cytoplasm
L	0005777	cellular_component	peroxisome
L	0006351	biological_process	DNA-templated transcription
L	0006360	biological_process	transcription by RNA polymerase I
L	0006361	biological_process	transcription initiation at RNA polymerase I promoter
L	0006362	biological_process	transcription elongation by RNA polymerase I
L	0006363	biological_process	termination of RNA polymerase I transcription
L	0006366	biological_process	transcription by RNA polymerase II
L	0006367	biological_process	transcription initiation at RNA polymerase II promoter
L	0006368	biological_process	transcription elongation by RNA polymerase II
L	0006383	biological_process	transcription by RNA polymerase III
L	0006384	biological_process	transcription initiation at RNA polymerase III promoter
L	0006386	biological_process	termination of RNA polymerase III transcription
L	0008270	molecular_function	zinc ion binding
L	0042254	biological_process	ribosome biogenesis
L	0042790	biological_process	nucleolar large rRNA transcription by RNA polymerase I
L	0042797	biological_process	tRNA transcription by RNA polymerase III
L	0046872	molecular_function	metal ion binding
m	0000122	biological_process	negative regulation of transcription by RNA polymerase II
m	0001113	biological_process	transcription open complex formation at RNA polymerase II promoter
m	0003712	molecular_function	transcription coregulator activity
m	0003713	molecular_function	transcription coactivator activity
m	0005634	cellular_component	nucleus
m	0006357	biological_process	regulation of transcription by RNA polymerase II
m	0016592	cellular_component	mediator complex
m	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
m	0045944	biological_process	positive regulation of transcription by RNA polymerase II
m	0051123	biological_process	RNA polymerase II preinitiation complex assembly
m	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
m	0070847	cellular_component	core mediator complex
M	0000993	molecular_function	RNA polymerase II complex binding
M	0001113	biological_process	transcription open complex formation at RNA polymerase II promoter
M	0001139	molecular_function	RNA polymerase II complex recruiting activity
M	0001174	biological_process	transcriptional start site selection at RNA polymerase II promoter
M	0005515	molecular_function	protein binding
M	0005634	cellular_component	nucleus
M	0006352	biological_process	DNA-templated transcription initiation
M	0006367	biological_process	transcription initiation at RNA polymerase II promoter
M	0008270	molecular_function	zinc ion binding
M	0010467	biological_process	gene expression
M	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
M	0017025	molecular_function	TBP-class protein binding
M	0046872	molecular_function	metal ion binding
M	0051123	biological_process	RNA polymerase II preinitiation complex assembly
M	0070897	biological_process	transcription preinitiation complex assembly
M	0097550	cellular_component	transcription preinitiation complex
n	0000122	biological_process	negative regulation of transcription by RNA polymerase II
n	0003712	molecular_function	transcription coregulator activity
n	0003713	molecular_function	transcription coactivator activity
n	0003714	molecular_function	transcription corepressor activity
n	0005515	molecular_function	protein binding
n	0005634	cellular_component	nucleus
n	0006357	biological_process	regulation of transcription by RNA polymerase II
n	0016592	cellular_component	mediator complex
n	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
n	0045944	biological_process	positive regulation of transcription by RNA polymerase II
n	0051123	biological_process	RNA polymerase II preinitiation complex assembly
n	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
n	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
n	0070847	cellular_component	core mediator complex
o	0003712	molecular_function	transcription coregulator activity
o	0003713	molecular_function	transcription coactivator activity
o	0005515	molecular_function	protein binding
o	0005634	cellular_component	nucleus
o	0006281	biological_process	DNA repair
o	0006310	biological_process	DNA recombination
o	0006311	biological_process	meiotic gene conversion
o	0006355	biological_process	regulation of DNA-templated transcription
o	0006357	biological_process	regulation of transcription by RNA polymerase II
o	0006366	biological_process	transcription by RNA polymerase II
o	0016592	cellular_component	mediator complex
o	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
o	0051123	biological_process	RNA polymerase II preinitiation complex assembly
o	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
o	0070847	cellular_component	core mediator complex
O	0000126	cellular_component	transcription factor TFIIIB complex
O	0000979	molecular_function	RNA polymerase II core promoter sequence-specific DNA binding
O	0001016	molecular_function	RNA polymerase III transcription regulatory region sequence-specific DNA binding
O	0001092	molecular_function	TFIIA-class transcription factor complex binding
O	0001179	molecular_function	RNA polymerase I general transcription initiation factor binding
O	0001188	biological_process	RNA polymerase I preinitiation complex assembly
O	0003677	molecular_function	DNA binding
O	0003682	molecular_function	chromatin binding
O	0005515	molecular_function	protein binding
O	0005634	cellular_component	nucleus
O	0005654	cellular_component	nucleoplasm
O	0005667	cellular_component	transcription regulator complex
O	0005669	cellular_component	transcription factor TFIID complex
O	0005672	cellular_component	transcription factor TFIIA complex
O	0006352	biological_process	DNA-templated transcription initiation
O	0006359	biological_process	regulation of transcription by RNA polymerase III
O	0008301	molecular_function	DNA binding, bending
O	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
O	0032991	cellular_component	protein-containing complex
O	0042790	biological_process	nucleolar large rRNA transcription by RNA polymerase I
O	0045892	biological_process	negative regulation of DNA-templated transcription
O	0045944	biological_process	positive regulation of transcription by RNA polymerase II
O	0051123	biological_process	RNA polymerase II preinitiation complex assembly
O	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
O	0070898	biological_process	RNA polymerase III preinitiation complex assembly
O	0097718	molecular_function	disordered domain specific binding
O	0140297	molecular_function	DNA-binding transcription factor binding
p	0000122	biological_process	negative regulation of transcription by RNA polymerase II
p	0003674	molecular_function	molecular_function
p	0003712	molecular_function	transcription coregulator activity
p	0005515	molecular_function	protein binding
p	0005634	cellular_component	nucleus
p	0006357	biological_process	regulation of transcription by RNA polymerase II
p	0016592	cellular_component	mediator complex
p	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
p	0045944	biological_process	positive regulation of transcription by RNA polymerase II
p	0051123	biological_process	RNA polymerase II preinitiation complex assembly
p	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
p	0070847	cellular_component	core mediator complex
Q	0001096	molecular_function	TFIIF-class transcription factor complex binding
Q	0001174	biological_process	transcriptional start site selection at RNA polymerase II promoter
Q	0003677	molecular_function	DNA binding
Q	0005634	cellular_component	nucleus
Q	0005674	cellular_component	transcription factor TFIIF complex
Q	0006355	biological_process	regulation of DNA-templated transcription
Q	0006367	biological_process	transcription initiation at RNA polymerase II promoter
Q	0006368	biological_process	transcription elongation by RNA polymerase II
Q	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
Q	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
Q	0051123	biological_process	RNA polymerase II preinitiation complex assembly
Q	0072542	molecular_function	protein phosphatase activator activity
r	0000786	cellular_component	nucleosome
r	0003677	molecular_function	DNA binding
r	0005515	molecular_function	protein binding
r	0005634	cellular_component	nucleus
r	0005654	cellular_component	nucleoplasm
r	0005694	cellular_component	chromosome
r	0030527	molecular_function	structural constituent of chromatin
r	0046982	molecular_function	protein heterodimerization activity
R	0000166	molecular_function	nucleotide binding
R	0000993	molecular_function	RNA polymerase II complex binding
R	0001174	biological_process	transcriptional start site selection at RNA polymerase II promoter
R	0003677	molecular_function	DNA binding
R	0005515	molecular_function	protein binding
R	0005634	cellular_component	nucleus
R	0005674	cellular_component	transcription factor TFIIF complex
R	0006355	biological_process	regulation of DNA-templated transcription
R	0006366	biological_process	transcription by RNA polymerase II
R	0006367	biological_process	transcription initiation at RNA polymerase II promoter
R	0006368	biological_process	transcription elongation by RNA polymerase II
R	0051123	biological_process	RNA polymerase II preinitiation complex assembly
s	0000786	cellular_component	nucleosome
s	0003677	molecular_function	DNA binding
s	0005515	molecular_function	protein binding
s	0005634	cellular_component	nucleus
s	0005694	cellular_component	chromosome
s	0006334	biological_process	nucleosome assembly
s	0030527	molecular_function	structural constituent of chromatin
s	0046982	molecular_function	protein heterodimerization activity
t	0000786	cellular_component	nucleosome
t	0003677	molecular_function	DNA binding
t	0005634	cellular_component	nucleus
t	0005694	cellular_component	chromosome
t	0030527	molecular_function	structural constituent of chromatin
t	0046982	molecular_function	protein heterodimerization activity
u	0000786	cellular_component	nucleosome
u	0003677	molecular_function	DNA binding
u	0005515	molecular_function	protein binding
u	0005634	cellular_component	nucleus
u	0005694	cellular_component	chromosome
u	0030527	molecular_function	structural constituent of chromatin
u	0046982	molecular_function	protein heterodimerization activity
U	0000979	molecular_function	RNA polymerase II core promoter sequence-specific DNA binding
U	0003712	molecular_function	transcription coregulator activity
U	0005515	molecular_function	protein binding
U	0005634	cellular_component	nucleus
U	0005672	cellular_component	transcription factor TFIIA complex
U	0005737	cellular_component	cytoplasm
U	0006366	biological_process	transcription by RNA polymerase II
U	0006367	biological_process	transcription initiation at RNA polymerase II promoter
U	0017025	molecular_function	TBP-class protein binding
U	0045944	biological_process	positive regulation of transcription by RNA polymerase II
U	0051123	biological_process	RNA polymerase II preinitiation complex assembly
U	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
v	0000786	cellular_component	nucleosome
v	0003677	molecular_function	DNA binding
v	0005515	molecular_function	protein binding
v	0005634	cellular_component	nucleus
v	0005654	cellular_component	nucleoplasm
v	0005694	cellular_component	chromosome
v	0030527	molecular_function	structural constituent of chromatin
v	0046982	molecular_function	protein heterodimerization activity
V	0000979	molecular_function	RNA polymerase II core promoter sequence-specific DNA binding
V	0005515	molecular_function	protein binding
V	0005634	cellular_component	nucleus
V	0005672	cellular_component	transcription factor TFIIA complex
V	0005737	cellular_component	cytoplasm
V	0006367	biological_process	transcription initiation at RNA polymerase II promoter
V	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
V	0017025	molecular_function	TBP-class protein binding
V	0045944	biological_process	positive regulation of transcription by RNA polymerase II
V	0051123	biological_process	RNA polymerase II preinitiation complex assembly
V	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
w	0000786	cellular_component	nucleosome
w	0003677	molecular_function	DNA binding
w	0005515	molecular_function	protein binding
w	0005634	cellular_component	nucleus
w	0005694	cellular_component	chromosome
w	0006334	biological_process	nucleosome assembly
w	0030527	molecular_function	structural constituent of chromatin
w	0046982	molecular_function	protein heterodimerization activity
W	0000993	molecular_function	RNA polymerase II complex binding
W	0001097	molecular_function	TFIIH-class transcription factor complex binding
W	0001113	biological_process	transcription open complex formation at RNA polymerase II promoter
W	0003697	molecular_function	single-stranded DNA binding
W	0005515	molecular_function	protein binding
W	0005634	cellular_component	nucleus
W	0005673	cellular_component	transcription factor TFIIE complex
W	0005739	cellular_component	mitochondrion
W	0006366	biological_process	transcription by RNA polymerase II
W	0006367	biological_process	transcription initiation at RNA polymerase II promoter
W	0008270	molecular_function	zinc ion binding
W	0046872	molecular_function	metal ion binding
W	0097550	cellular_component	transcription preinitiation complex
x	0000786	cellular_component	nucleosome
x	0003677	molecular_function	DNA binding
x	0005634	cellular_component	nucleus
x	0005694	cellular_component	chromosome
x	0030527	molecular_function	structural constituent of chromatin
x	0046982	molecular_function	protein heterodimerization activity
X	0000993	molecular_function	RNA polymerase II complex binding
X	0001097	molecular_function	TFIIH-class transcription factor complex binding
X	0003677	molecular_function	DNA binding
X	0003697	molecular_function	single-stranded DNA binding
X	0005515	molecular_function	protein binding
X	0005634	cellular_component	nucleus
X	0005673	cellular_component	transcription factor TFIIE complex
X	0006366	biological_process	transcription by RNA polymerase II
X	0006367	biological_process	transcription initiation at RNA polymerase II promoter
X	0097550	cellular_component	transcription preinitiation complex
y	0000786	cellular_component	nucleosome
y	0003677	molecular_function	DNA binding
y	0005515	molecular_function	protein binding
y	0005634	cellular_component	nucleus
y	0005694	cellular_component	chromosome
y	0030527	molecular_function	structural constituent of chromatin
y	0046982	molecular_function	protein heterodimerization activity

Functional Information from PROSITE/UniProt

site_id	PS00014
Number of Residues	4
Details	ER_TARGET Endoplasmic reticulum targeting sequence. SEEL

Chain	Residue	Details
3	SER318-LEU321

---

site_id	PS00028
Number of Residues	21
Details	ZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. Ced..CkqeFcvdcdvfiHeil..H

Chain	Residue	Details
6	CYS429-HIS449

---

site_id	PS00046
Number of Residues	7
Details	HISTONE_H2A Histone H2A signature. AGLqFPV

Chain	Residue	Details
x	ALA21-VAL27

---

site_id	PS00047
Number of Residues	5
Details	HISTONE_H4 Histone H4 signature. GAKRH

Chain	Residue	Details
s	GLY14-HIS18

---

site_id	PS00115
Number of Residues	7
Details	RNA_POL_II_REPEAT Eukaryotic RNA polymerase II heptapeptide repeat. YSPTSPA

Chain	Residue	Details
A	TYR1563-ALA1569
A	TYR1640-SER1646
A	TYR1647-SER1653
A	TYR1661-SER1667
A	TYR1668-SER1674
A	TYR1675-SER1681
A	TYR1682-SER1688
A	TYR1689-ALA1695
A	TYR1696-SER1702
A	TYR1703-SER1709
A	TYR1710-SER1716
A	TYR1570-SER1576
A	TYR1717-SER1723
A	TYR1724-ASN1730
A	TYR1731-SER1737
A	TYR1577-SER1583
A	TYR1584-SER1590
A	TYR1591-SER1597
A	TYR1598-SER1604
A	TYR1605-SER1611
A	TYR1612-SER1632
A	TYR1633-SER1639

---

site_id	PS00322
Number of Residues	7
Details	HISTONE_H3_1 Histone H3 signature 1. KAPRKQL

Chain	Residue	Details
r	LYS14-LEU20

---

site_id	PS00351
Number of Residues	50
Details	TFIID Transcription factor TFIID repeat signature. YnPkrFaaVImRirePKttaLIFaSGKMvvtGAKseddsklAsrkyariI

Chain	Residue	Details
O	TYR94-ILE143
O	TYR185-LEU234

---

site_id	PS00357
Number of Residues	23
Details	HISTONE_H2B Histone H2B signature. REIQTavRlLLpGELaKHAVSEG

Chain	Residue	Details
y	ARG89-GLY111

---

site_id	PS00387
Number of Residues	7
Details	PPASE Inorganic pyrophosphatase signature. DDDEMDI

Chain	Residue	Details
W	ASP471-ILE477

---

site_id	PS00446
Number of Residues	41
Details	RNA_POL_D_30KD RNA polymerases D / 30 to 40 Kd subunits signature. NSLRRvmiaeiptlAidsVevetNtTvlaDEfIAhRLGLIP

Chain	Residue	Details
C	ASN31-PRO71

---

site_id	PS00466
Number of Residues	36
Details	ZF_TFIIS_1 Zinc finger TFIIS-type signature. CpkChsrenvffqSQQRRkDTSmvlffvCls...CshiF

Chain	Residue	Details
I	CYS75-PHE110

---

site_id	PS00518
Number of Residues	10
Details	ZF_RING_1 Zinc finger RING-type signature. CyHrICesCV

Chain	Residue	Details
3	CYS34-VAL43

---

site_id	PS00690
Number of Residues	10
Details	DEAH_ATP_HELICASE DEAH-box subfamily ATP-dependent helicases signature. SiVIFDEAHN

Chain	Residue	Details
0	SER230-ASN239

---

site_id	PS00782
Number of Residues	16
Details	TFIIB Transcription factor TFIIB repeat signature. GKsmeSIMAASILIGC

Chain	Residue	Details
M	GLY165-CYS180

---

site_id	PS00959
Number of Residues	9
Details	HISTONE_H3_2 Histone H3 signature 2. PFqRLVREI

Chain	Residue	Details
r	PRO66-ILE74

---

site_id	PS01030
Number of Residues	27
Details	RNA_POL_M_15KD RNA polymerases M / 15 Kd subunits signature. FCRDCNNMLypredkennrllfeCrtC

Chain	Residue	Details
I	PHE6-CYS32

---

site_id	PS01110
Number of Residues	14
Details	RNA_POL_H_23KD RNA polymerases H / 23 Kd subunits signature. HELVPKHirLssDE

Chain	Residue	Details
E	HIS147-GLU160

---

site_id	PS01111
Number of Residues	15
Details	RNA_POL_K_14KD RNA polymerases K / 14 to 18 Kd subunits signature. TkYErARiLGtRAlQ

Chain	Residue	Details
F	THR86-GLN100

---

site_id	PS01112
Number of Residues	10
Details	RNA_POL_N_8KD RNA polymerases N / 8 Kd subunits signature. IVPVrCFSCG

Chain	Residue	Details
J	ILE2-GLY11

---

site_id	PS01154
Number of Residues	32
Details	RNA_POL_L_13KD RNA polymerases L / 13 to 16 Kd subunits signature. FekEdHTLgNlIraeLlndrkVlfaaYkveHP

Chain	Residue	Details
K	PHE35-PRO66

---

site_id	PS01166
Number of Residues	13
Details	RNA_POL_BETA RNA polymerases beta chain signature. GdKFASrHGQKGT

Chain	Residue	Details
B	GLY977-THR989

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P0C1H4

Chain	Residue	Details
u	LYS2
A	ASP483
A	ASP485
u	LYS9
u	LYS12
u	LYS17
y	LYS2
y	LYS9
y	LYS12
y	LYS17
A	ASP481

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0000269|PubMed:12757711

Chain	Residue	Details
u	SER11
y	SER11
M	CYS45
M	CYS48
B	CYS1185

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	CARBOHYD: O-linked (GlcNAc) serine => ECO:0000250|UniProtKB:P62807

Chain	Residue	Details
u	SER109
y	SER109
x	LYS9
x	LYS95

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:P0C1H4

Chain	Residue	Details
u	LYS117
x	LYS36
y	LYS117
I	CYS106

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	MOD_RES: N6-(2-hydroxyisobutyryl)lysine => ECO:0000250|UniProtKB:P0C0S8

Chain	Residue	Details
t	LYS74
t	LYS75
x	LYS74
x	LYS75
w	LYS8
w	LYS16
w	LYS44
w	LYS79

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	MOD_RES: N5-methylglutamine => ECO:0000250

Chain	Residue	Details
t	GLN104
x	GLN104
w	LYS12
w	LYS20

---

site_id	SWS_FT_FI7
Number of Residues	2
Details	MOD_RES: N6-glutaryllysine; alternate => ECO:0000250|UniProtKB:P0C0S8

Chain	Residue	Details
t	LYS118
x	LYS118
w	LYS31
w	LYS91

---

site_id	SWS_FT_FI8
Number of Residues	8
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250

Chain	Residue	Details
t	LYS13
w	SER47
t	LYS15
t	LYS119
x	LYS13
x	LYS15
x	LYS119

---

site_id	SWS_FT_FI9
Number of Residues	4
Details	MOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:P62805

Chain	Residue	Details
s	TYR51
s	TYR88
w	TYR51
w	TYR88

---

site_id	SWS_FT_FI10
Number of Residues	2
Details	MOD_RES: N6-glutaryllysine; alternate => ECO:0000250|UniProtKB:P62805

Chain	Residue	Details
s	LYS59
v	LYS64
w	LYS59
r	LYS27
r	LYS36
r	LYS64
v	LYS18
v	LYS23
v	LYS27
v	LYS36

---

site_id	SWS_FT_FI11
Number of Residues	2
Details	MOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:P62805

Chain	Residue	Details
s	LYS77
w	LYS77

---

site_id	SWS_FT_FI12
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in UFM1); alternate => ECO:0000250|UniProtKB:P62805

Chain	Residue	Details
s	LYS31
w	LYS31

---

site_id	SWS_FT_FI13
Number of Residues	4
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate => ECO:0000250|UniProtKB:P62805

Chain	Residue	Details
r	LYS37
s	LYS91
w	LYS91

---

site_id	SWS_FT_FI14
Number of Residues	2
Details	MOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:Q71DI3

Chain	Residue	Details
r	TYR41
v	TYR41

---

site_id	SWS_FT_FI15
Number of Residues	4
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P84228

Chain	Residue	Details
r	LYS56
r	LYS79
v	LYS56
v	LYS79

---

site_id	SWS_FT_FI16
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q71DI3

Chain	Residue	Details
r	SER57
v	SER57

---

site_id	SWS_FT_FI17
Number of Residues	4
Details	MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:Q71DI3

Chain	Residue	Details
r	THR80
r	THR107
v	THR80
v	THR107

---

site_id	SWS_FT_FI18
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P84243

Chain	Residue	Details
r	SER86
v	SER86

---

site_id	SWS_FT_FI19
Number of Residues	2
Details	MOD_RES: N6-glutaryllysine; alternate => ECO:0000250|UniProtKB:Q71DI3

Chain	Residue	Details
r	LYS115
v	LYS115

---

site_id	SWS_FT_FI20
Number of Residues	2
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:Q71DI3

Chain	Residue	Details
r	LYS122
v	LYS122

---

site_id	SWS_FT_FI21
Number of Residues	2
Details	LIPID: S-palmitoyl cysteine => ECO:0000250|UniProtKB:Q71DI3

Chain	Residue	Details
r	ALA110
v	ALA110

---

Catalytic Information from CSA

site_id	MCSA1
Number of Residues	4
Details	M-CSA 788

Chain	Residue	Details
A	ASP481	metal ligand
A	ASP483	metal ligand
A	ASP485	metal ligand
A	HIS1085	proton acceptor, proton donor

---