Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

8CDU

Rnase R bound to a 30S degradation intermediate (main state)

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0003676	molecular_function	nucleic acid binding
C	0003723	molecular_function	RNA binding
C	0004518	molecular_function	nuclease activity
C	0004527	molecular_function	exonuclease activity
C	0004540	molecular_function	RNA nuclease activity
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006402	biological_process	mRNA catabolic process
C	0008859	molecular_function	exoribonuclease II activity
C	0016070	biological_process	RNA metabolic process
C	0016787	molecular_function	hydrolase activity
D	0003735	molecular_function	structural constituent of ribosome
D	0005515	molecular_function	protein binding
D	0005840	cellular_component	ribosome
D	0006412	biological_process	translation
D	0015935	cellular_component	small ribosomal subunit
D	0022627	cellular_component	cytosolic small ribosomal subunit
D	1990904	cellular_component	ribonucleoprotein complex
E	0003676	molecular_function	nucleic acid binding
E	0003723	molecular_function	RNA binding
E	0003729	molecular_function	mRNA binding
E	0003735	molecular_function	structural constituent of ribosome
E	0005840	cellular_component	ribosome
E	0006412	biological_process	translation
E	0019843	molecular_function	rRNA binding
E	0022627	cellular_component	cytosolic small ribosomal subunit
E	1990904	cellular_component	ribonucleoprotein complex
F	0003723	molecular_function	RNA binding
F	0003735	molecular_function	structural constituent of ribosome
F	0005840	cellular_component	ribosome
F	0006412	biological_process	translation
F	0015935	cellular_component	small ribosomal subunit
F	0019843	molecular_function	rRNA binding
F	0042274	biological_process	ribosomal small subunit biogenesis
F	1990904	cellular_component	ribonucleoprotein complex
G	0003723	molecular_function	RNA binding
G	0003735	molecular_function	structural constituent of ribosome
G	0005737	cellular_component	cytoplasm
G	0005840	cellular_component	ribosome
G	0006412	biological_process	translation
G	0015935	cellular_component	small ribosomal subunit
G	0019843	molecular_function	rRNA binding
G	0022627	cellular_component	cytosolic small ribosomal subunit
G	0042254	biological_process	ribosome biogenesis
G	0046677	biological_process	response to antibiotic
G	1990904	cellular_component	ribonucleoprotein complex
H	0000049	molecular_function	tRNA binding
H	0003723	molecular_function	RNA binding
H	0003729	molecular_function	mRNA binding
H	0003735	molecular_function	structural constituent of ribosome
H	0005840	cellular_component	ribosome
H	0006412	biological_process	translation
H	0015935	cellular_component	small ribosomal subunit
H	0019843	molecular_function	rRNA binding
H	0022627	cellular_component	cytosolic small ribosomal subunit
H	1990904	cellular_component	ribonucleoprotein complex
I	0003723	molecular_function	RNA binding
I	0003735	molecular_function	structural constituent of ribosome
I	0005737	cellular_component	cytoplasm
I	0005840	cellular_component	ribosome
I	0006412	biological_process	translation
I	0019843	molecular_function	rRNA binding
I	0022627	cellular_component	cytosolic small ribosomal subunit
I	1990904	cellular_component	ribonucleoprotein complex
J	0003723	molecular_function	RNA binding
J	0003735	molecular_function	structural constituent of ribosome
J	0005737	cellular_component	cytoplasm
J	0005840	cellular_component	ribosome
J	0006412	biological_process	translation
J	0015935	cellular_component	small ribosomal subunit
J	0022627	cellular_component	cytosolic small ribosomal subunit
J	1990904	cellular_component	ribonucleoprotein complex
K	0000049	molecular_function	tRNA binding
K	0003723	molecular_function	RNA binding
K	0003735	molecular_function	structural constituent of ribosome
K	0005840	cellular_component	ribosome
K	0006412	biological_process	translation
K	0015935	cellular_component	small ribosomal subunit
K	1990904	cellular_component	ribonucleoprotein complex
L	0000049	molecular_function	tRNA binding
L	0003723	molecular_function	RNA binding
L	0003735	molecular_function	structural constituent of ribosome
L	0005515	molecular_function	protein binding
L	0005840	cellular_component	ribosome
L	0006412	biological_process	translation
L	0015935	cellular_component	small ribosomal subunit
L	0019843	molecular_function	rRNA binding
L	0046677	biological_process	response to antibiotic
L	1990904	cellular_component	ribonucleoprotein complex
M	0000049	molecular_function	tRNA binding
M	0003676	molecular_function	nucleic acid binding
M	0003723	molecular_function	RNA binding
M	0003735	molecular_function	structural constituent of ribosome
M	0005829	cellular_component	cytosol
M	0005840	cellular_component	ribosome
M	0006412	biological_process	translation
M	0015935	cellular_component	small ribosomal subunit
M	0019843	molecular_function	rRNA binding
M	1990904	cellular_component	ribonucleoprotein complex
N	0003723	molecular_function	RNA binding
N	0003735	molecular_function	structural constituent of ribosome
N	0005840	cellular_component	ribosome
N	0006412	biological_process	translation
N	0008270	molecular_function	zinc ion binding
N	0015935	cellular_component	small ribosomal subunit
N	0019843	molecular_function	rRNA binding
N	0046872	molecular_function	metal ion binding
N	1990904	cellular_component	ribonucleoprotein complex
O	0003723	molecular_function	RNA binding
O	0003735	molecular_function	structural constituent of ribosome
O	0005737	cellular_component	cytoplasm
O	0005840	cellular_component	ribosome
O	0006412	biological_process	translation
O	0019843	molecular_function	rRNA binding
O	0022627	cellular_component	cytosolic small ribosomal subunit
O	1990904	cellular_component	ribonucleoprotein complex
P	0003735	molecular_function	structural constituent of ribosome
P	0005737	cellular_component	cytoplasm
P	0005840	cellular_component	ribosome
P	0006412	biological_process	translation
P	0015935	cellular_component	small ribosomal subunit
P	1990904	cellular_component	ribonucleoprotein complex
Q	0003723	molecular_function	RNA binding
Q	0003735	molecular_function	structural constituent of ribosome
Q	0005840	cellular_component	ribosome
Q	0006412	biological_process	translation
Q	0019843	molecular_function	rRNA binding
Q	0022627	cellular_component	cytosolic small ribosomal subunit
Q	1990904	cellular_component	ribonucleoprotein complex
R	0003723	molecular_function	RNA binding
R	0003735	molecular_function	structural constituent of ribosome
R	0005737	cellular_component	cytoplasm
R	0005840	cellular_component	ribosome
R	0006412	biological_process	translation
R	0015935	cellular_component	small ribosomal subunit
R	0019843	molecular_function	rRNA binding
R	0022627	cellular_component	cytosolic small ribosomal subunit
R	1990904	cellular_component	ribonucleoprotein complex
S	0003723	molecular_function	RNA binding
S	0003735	molecular_function	structural constituent of ribosome
S	0005829	cellular_component	cytosol
S	0005840	cellular_component	ribosome
S	0006412	biological_process	translation
S	0015935	cellular_component	small ribosomal subunit
S	0019843	molecular_function	rRNA binding
S	0070181	molecular_function	small ribosomal subunit rRNA binding
S	1990904	cellular_component	ribonucleoprotein complex
T	0003723	molecular_function	RNA binding
T	0003735	molecular_function	structural constituent of ribosome
T	0005737	cellular_component	cytoplasm
T	0005840	cellular_component	ribosome
T	0006412	biological_process	translation
T	0019843	molecular_function	rRNA binding
T	0070181	molecular_function	small ribosomal subunit rRNA binding
T	1990904	cellular_component	ribonucleoprotein complex
U	0003723	molecular_function	RNA binding
U	0003735	molecular_function	structural constituent of ribosome
U	0005840	cellular_component	ribosome
U	0006412	biological_process	translation
U	0019843	molecular_function	rRNA binding
U	0022627	cellular_component	cytosolic small ribosomal subunit
U	0070181	molecular_function	small ribosomal subunit rRNA binding
U	1990904	cellular_component	ribonucleoprotein complex
V	0003723	molecular_function	RNA binding
V	0003735	molecular_function	structural constituent of ribosome
V	0005515	molecular_function	protein binding
V	0005840	cellular_component	ribosome
V	0006412	biological_process	translation
V	0019843	molecular_function	rRNA binding
V	0022627	cellular_component	cytosolic small ribosomal subunit
V	1990904	cellular_component	ribonucleoprotein complex

Functional Information from PROSITE/UniProt

site_id	PS00052
Number of Residues	27
Details	RIBOSOMAL_S7 Ribosomal protein S7 signature. SkLvsrLInkmmidGKKgksqtILykS

Chain	Residue	Details
H	SER20-SER46

site_id	PS00053
Number of Residues	18
Details	RIBOSOMAL_S8 Ribosomal protein S8 signature. GiaIISTSqGVLtdkeAR

Chain	Residue	Details
I	GLY102-ARG119

site_id	PS00054
Number of Residues	23
Details	RIBOSOMAL_S11 Ribosomal protein S11 signature. IrALqaA.GLeVtairDvTPvPHN

Chain	Residue	Details
V	ILE99-ASN121

site_id	PS00055
Number of Residues	8
Details	RIBOSOMAL_S12 Ribosomal protein S12 signature. KkPNSAlR

Chain	Residue	Details
L	LYS56-ARG63

site_id	PS00056
Number of Residues	13
Details	RIBOSOMAL_S17 Ribosomal protein S17 signature. GDiVkImEtRPLS

Chain	Residue	Details
Q	GLY58-SER70

site_id	PS00057
Number of Residues	24
Details	RIBOSOMAL_S18 Ribosomal protein S18 signature. IDYkd.VdlLkkFVSEr.GKIlprRV

Chain	Residue	Details
U	ILE26-VAL49

site_id	PS00323
Number of Residues	25
Details	RIBOSOMAL_S19 Ribosomal protein S19 signature. DGRkhvpvfIsedmVGhkLGEFapT

Chain	Residue	Details
R	ASP53-THR77

site_id	PS00360
Number of Residues	19
Details	RIBOSOMAL_S9 Ribosomal protein S9 signature. GGGlsGQagAirhGiARAL

Chain	Residue	Details
J	GLY69-LEU87

site_id	PS00361
Number of Residues	16
Details	RIBOSOMAL_S10 Ribosomal protein S10 signature. AkrsGAsvsGPIpLPT

Chain	Residue	Details
K	ALA29-THR44

site_id	PS00362
Number of Residues	31
Details	RIBOSOMAL_S15 Ribosomal protein S15 signature. LneHLrthKkDhhSrrgLlkMvgkrrnLltY

Chain	Residue	Details
O	LEU39-TYR69

site_id	PS00527
Number of Residues	23
Details	RIBOSOMAL_S14 Ribosomal protein S14 signature. R.CercgrphsvirkFKLCRiCFR

Chain	Residue	Details
N	ARG23-ARG45

site_id	PS00548
Number of Residues	35
Details	RIBOSOMAL_S3 Ribosomal protein S3 signature. ARseyyseGtVplHt..LradIDyatseadTtyGklG

Chain	Residue	Details
E	ALA162-GLY196

site_id	PS00585
Number of Residues	33
Details	RIBOSOMAL_S5 Ribosomal protein S5 signature. GRrfrFaAlvVVGDkn.GhVGfGtgkaq.EVpe.AI

Chain	Residue	Details
G	GLY28-ILE60

site_id	PS00632
Number of Residues	25
Details	RIBOSOMAL_S4 Ribosomal protein S4 signature. LDsRLdnvVYKlglArTrrqARqLV

Chain	Residue	Details
F	LEU90-VAL114

site_id	PS00646
Number of Residues	14
Details	RIBOSOMAL_S13_1 Ribosomal protein S13 signature. RGiRHrrGlpVRGQ

Chain	Residue	Details
M	ARG87-GLN100

site_id	PS00732
Number of Residues	10
Details	RIBOSOMAL_S16 Ribosomal protein S16 signature. VkIRLKRMGA

Chain	Residue	Details
P	VAL3-ALA12

site_id	PS00962
Number of Residues	12
Details	RIBOSOMAL_S2_1 Ribosomal protein S2 signature 1. MkQLLEAGVHFG

Chain	Residue	Details
D	MET6-GLY17

site_id	PS00963
Number of Residues	25
Details	RIBOSOMAL_S2_2 Ribosomal protein S2 signature 2. PdaLFIiDprkEriaVaEarklNIP

Chain	Residue	Details
D	PRO158-PRO182

site_id	PS01048
Number of Residues	10
Details	RIBOSOMAL_S6 Ribosomal protein S6 signature. GkRRLAYeIN

Chain	Residue	Details
T	GLY44-ASN53

site_id	PS01175
Number of Residues	25
Details	RIBONUCLEASE_II Ribonuclease II family signature. HFGLstef.YThFTSPIRRYpDlivH

Chain	Residue	Details
C	HIS545-HIS569

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	329
Details	Domain: {"description":"RNB","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	80
Details	Domain: {"description":"S1 motif","evidences":[{"source":"HAMAP-Rule","id":"MF_01895","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	68
Details	Domain: {"description":"KH type-2","evidences":[{"source":"HAMAP-Rule","id":"MF_01309","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	63
Details	Domain: {"description":"S5 DRBM"}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	22
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	1
Details	Site: {"description":"Not modified","evidences":[{"source":"PubMed","id":"19653700","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"unpublished observations","publicationDate":"AUG-2002","authors":["Ochi K.","Takashi I.","Forbes A.","Kelleher N.L.","Garavelli J.S."]}}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01364","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)