8CBR
HIV-1 Integrase Catalytic Core Domain and C-Terminal Domain in Complex with Allosteric Integrase Inhibitor BDM-2
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0015074 | biological_process | DNA integration |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0015074 | biological_process | DNA integration |
| C | 0003676 | molecular_function | nucleic acid binding |
| C | 0015074 | biological_process | DNA integration |
| D | 0003676 | molecular_function | nucleic acid binding |
| D | 0015074 | biological_process | DNA integration |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 188 |
| Details | DNA_BIND: Integrase-type => ECO:0000255|PROSITE-ProRule:PRU00506 |
| Chain | Residue | Details |
| A | PHE223-ASP270 | |
| B | PHE-16-ASP31 | |
| C | PHE223-ASP270 | |
| D | PHE-16-ASP31 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00450 |
| Chain | Residue | Details |
| A | CYS280 | |
| B | CYS41 | |
| C | CYS280 | |
| D | CYS41 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | ASP303 | |
| B | ASP64 | |
| B | ASP116 | |
| C | ASP303 | |
| C | ASP355 | |
| D | ASP64 | |
| D | ASP116 | |
| A | ASP355 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:P04585 |
| Chain | Residue | Details |
| A | GLU391 | |
| B | GLU152 | |
| C | GLU391 | |
| D | GLU152 |
