Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004096 | molecular_function | catalase activity |
| A | 0004601 | molecular_function | peroxidase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005777 | cellular_component | peroxisome |
| A | 0005782 | cellular_component | peroxisomal matrix |
| A | 0006979 | biological_process | response to oxidative stress |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019899 | molecular_function | enzyme binding |
| A | 0020037 | molecular_function | heme binding |
| A | 0042542 | biological_process | response to hydrogen peroxide |
| A | 0042744 | biological_process | hydrogen peroxide catabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051781 | biological_process | positive regulation of cell division |
| A | 0061692 | biological_process | cellular detoxification of hydrogen peroxide |
| A | 0062151 | cellular_component | catalase complex |
| B | 0004096 | molecular_function | catalase activity |
| B | 0004601 | molecular_function | peroxidase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005739 | cellular_component | mitochondrion |
| B | 0005777 | cellular_component | peroxisome |
| B | 0005782 | cellular_component | peroxisomal matrix |
| B | 0006979 | biological_process | response to oxidative stress |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0019899 | molecular_function | enzyme binding |
| B | 0020037 | molecular_function | heme binding |
| B | 0042542 | biological_process | response to hydrogen peroxide |
| B | 0042744 | biological_process | hydrogen peroxide catabolic process |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051781 | biological_process | positive regulation of cell division |
| B | 0061692 | biological_process | cellular detoxification of hydrogen peroxide |
| B | 0062151 | cellular_component | catalase complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE HEM A 507 |
| Chain | Residue |
| A | ARG71 |
| A | ALA157 |
| A | PHE160 |
| A | SER216 |
| A | LEU298 |
| A | PHE333 |
| A | ARG353 |
| A | ALA356 |
| A | TYR357 |
| A | THR360 |
| A | HIS361 |
| A | VAL72 |
| A | ARG364 |
| A | HOH509 |
| A | HOH511 |
| B | ASP64 |
| A | VAL73 |
| A | HIS74 |
| A | ARG111 |
| A | GLY130 |
| A | VAL145 |
| A | GLY146 |
| A | ASN147 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE NDP A 508 |
| Chain | Residue |
| A | HIS193 |
| A | PHE197 |
| A | SER200 |
| A | ARG202 |
| A | LYS236 |
| A | ILE241 |
| A | VAL301 |
| A | TRP302 |
| A | PRO303 |
| A | HIS304 |
| A | GLN441 |
| A | THR444 |
| A | PHE445 |
| A | VAL449 |
| A | HOH512 |
| site_id | AC3 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE HEM B 507 |
| Chain | Residue |
| A | ASP64 |
| B | ARG71 |
| B | VAL72 |
| B | VAL73 |
| B | HIS74 |
| B | ARG111 |
| B | GLY130 |
| B | VAL145 |
| B | GLY146 |
| B | ASN147 |
| B | ALA157 |
| B | PHE160 |
| B | GLY215 |
| B | PHE333 |
| B | MET349 |
| B | ARG353 |
| B | ALA356 |
| B | TYR357 |
| B | THR360 |
| B | HIS361 |
| B | ARG364 |
| B | HOH518 |
| B | HOH520 |
| site_id | AC4 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE NDP B 508 |
| Chain | Residue |
| B | HIS193 |
| B | PHE197 |
| B | SER200 |
| B | ARG202 |
| B | HIS234 |
| B | LYS236 |
| B | ILE241 |
| B | VAL301 |
| B | TRP302 |
| B | PRO303 |
| B | HIS304 |
| B | GLN441 |
| B | PHE445 |
| B | VAL449 |
| B | HOH521 |
Functional Information from PROSITE/UniProt
| site_id | PS00437 |
| Number of Residues | 9 |
| Details | CATALASE_1 Catalase proximal heme-ligand signature. RLFAYpDTH |
| Chain | Residue | Details |
| A | ARG353-HIS361 | |
| site_id | PS00438 |
| Number of Residues | 17 |
| Details | CATALASE_2 Catalase proximal active site signature. FdReripERvvHakGAG |
| Chain | Residue | Details |
| A | PHE63-GLY79 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10013","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"7328661","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10013","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 22 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10417406","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4BLC","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P04040","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Binding site: {"description":"axial binding residue","evidences":[{"source":"PubMed","id":"10417406","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4BLC","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P04040","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P24270","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI8 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P24270","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI9 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P24270","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI10 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P24270","evidenceCode":"ECO:0000250"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1iph |
| Chain | Residue | Details |
| A | SER113 | |
| A | HIS74 | |
| A | ASN147 | |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1iph |
| Chain | Residue | Details |
| B | SER113 | |
| B | HIS74 | |
| B | ASN147 | |
