8C9A

Cryo-EM captures early ribosome assembly in action

Functional Information from GO Data

Chain	GOid	namespace	contents
2	0002181	biological_process	cytoplasmic translation
2	0003735	molecular_function	structural constituent of ribosome
2	0005515	molecular_function	protein binding
2	0005737	cellular_component	cytoplasm
2	0005840	cellular_component	ribosome
2	0006412	biological_process	translation
2	0022625	cellular_component	cytosolic large ribosomal subunit
2	1990904	cellular_component	ribonucleoprotein complex
E	0001070	molecular_function	RNA-binding transcription regulator activity
E	0002181	biological_process	cytoplasmic translation
E	0003677	molecular_function	DNA binding
E	0003735	molecular_function	structural constituent of ribosome
E	0005515	molecular_function	protein binding
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0005840	cellular_component	ribosome
E	0006353	biological_process	DNA-templated transcription termination
E	0006412	biological_process	translation
E	0006417	biological_process	regulation of translation
E	0015934	cellular_component	large ribosomal subunit
E	0017148	biological_process	negative regulation of translation
E	0019843	molecular_function	rRNA binding
E	0022625	cellular_component	cytosolic large ribosomal subunit
E	0030371	molecular_function	translation repressor activity
E	0031555	biological_process	transcriptional attenuation
E	0042255	biological_process	ribosome assembly
E	0045892	biological_process	negative regulation of DNA-templated transcription
E	0046677	biological_process	response to antibiotic
E	0048027	molecular_function	mRNA 5'-UTR binding
E	0060698	molecular_function	endoribonuclease inhibitor activity
E	1990904	cellular_component	ribonucleoprotein complex
E	2000766	biological_process	negative regulation of cytoplasmic translation
S	0002181	biological_process	cytoplasmic translation
S	0003735	molecular_function	structural constituent of ribosome
S	0005515	molecular_function	protein binding
S	0005737	cellular_component	cytoplasm
S	0005829	cellular_component	cytosol
S	0005840	cellular_component	ribosome
S	0006412	biological_process	translation
S	0015934	cellular_component	large ribosomal subunit
S	0019843	molecular_function	rRNA binding
S	0022625	cellular_component	cytosolic large ribosomal subunit
S	0042255	biological_process	ribosome assembly
S	0042256	biological_process	cytosolic ribosome assembly
S	0046677	biological_process	response to antibiotic
S	0070180	molecular_function	large ribosomal subunit rRNA binding
S	1902626	biological_process	assembly of large subunit precursor of preribosome
S	1990904	cellular_component	ribonucleoprotein complex
T	0000027	biological_process	ribosomal large subunit assembly
T	0002181	biological_process	cytoplasmic translation
T	0003735	molecular_function	structural constituent of ribosome
T	0005515	molecular_function	protein binding
T	0005737	cellular_component	cytoplasm
T	0005840	cellular_component	ribosome
T	0006412	biological_process	translation
T	0019843	molecular_function	rRNA binding
T	0022625	cellular_component	cytosolic large ribosomal subunit
T	1990904	cellular_component	ribonucleoprotein complex
U	0000027	biological_process	ribosomal large subunit assembly
U	0002181	biological_process	cytoplasmic translation
U	0003723	molecular_function	RNA binding
U	0003735	molecular_function	structural constituent of ribosome
U	0005515	molecular_function	protein binding
U	0005737	cellular_component	cytoplasm
U	0005829	cellular_component	cytosol
U	0005840	cellular_component	ribosome
U	0006412	biological_process	translation
U	0019843	molecular_function	rRNA binding
U	0022625	cellular_component	cytosolic large ribosomal subunit
U	0070180	molecular_function	large ribosomal subunit rRNA binding
U	1990904	cellular_component	ribonucleoprotein complex
Y	0000027	biological_process	ribosomal large subunit assembly
Y	0002181	biological_process	cytoplasmic translation
Y	0003735	molecular_function	structural constituent of ribosome
Y	0005737	cellular_component	cytoplasm
Y	0005840	cellular_component	ribosome
Y	0006412	biological_process	translation
Y	0019843	molecular_function	rRNA binding
Y	0022625	cellular_component	cytosolic large ribosomal subunit
Y	1990904	cellular_component	ribonucleoprotein complex

Functional Information from PROSITE/UniProt

site_id	PS00050
Number of Residues	16
Details	RIBOSOMAL_L23 Ribosomal protein L23 signature. KKAYVTLKegqnldfV

Chain	Residue	Details
T	LYS81-VAL96

---

site_id	PS00430
Number of Residues	66
Details	TONB_DEPENDENT_REC_1 TonB-dependent receptor (TBDR) proteins signature 1. mireerllkvlraphvsekastameksntivlkvakdatkaeikaavqklfevevevv.........................................................NTLVVKGK

Chain	Residue	Details
T	MET1-LYS66

---

site_id	PS00464
Number of Residues	25
Details	RIBOSOMAL_L22 Ribosomal protein L22 signature. KriMpRAkGRadrilkrtSHITVvV

Chain	Residue	Details
S	LYS83-VAL107

---

site_id	PS00579
Number of Residues	15
Details	RIBOSOMAL_L29 Ribosomal protein L29 signature. QSHLLKqVRRDVARV

Chain	Residue	Details
Y	GLN39-VAL53

---

site_id	PS00784
Number of Residues	20
Details	RIBOSOMAL_L34 Ribosomal protein L34 signature. KRTFQpsvlkRnrsh.GFraR

Chain	Residue	Details
2	LYS2-ARG21

---

site_id	PS01108
Number of Residues	18
Details	RIBOSOMAL_L24 Ribosomal protein L24 signature. DDeViVLtGkdKGkr.GkV

Chain	Residue	Details
U	ASP7-VAL24

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:34403461, ECO:0000269|PubMed:34504068, ECO:0000312|PDB:7O19, ECO:0000312|PDB:7O1A, ECO:0000312|PDB:7O1C, ECO:0000312|PDB:7OIZ, ECO:0000312|PDB:7OJ0

Chain	Residue	Details
S	LYS90

---