8C95

Cryo-EM captures early ribosome assembly in action

Functional Information from GO Data

Chain	GOid	namespace	contents
2	0002181	biological_process	cytoplasmic translation
2	0003735	molecular_function	structural constituent of ribosome
2	0005515	molecular_function	protein binding
2	0005737	cellular_component	cytoplasm
2	0005840	cellular_component	ribosome
2	0006412	biological_process	translation
2	0022625	cellular_component	cytosolic large ribosomal subunit
2	1990904	cellular_component	ribonucleoprotein complex
E	0001070	molecular_function	RNA-binding transcription regulator activity
E	0002181	biological_process	cytoplasmic translation
E	0003677	molecular_function	DNA binding
E	0003735	molecular_function	structural constituent of ribosome
E	0005515	molecular_function	protein binding
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0005840	cellular_component	ribosome
E	0006353	biological_process	DNA-templated transcription termination
E	0006412	biological_process	translation
E	0006417	biological_process	regulation of translation
E	0015934	cellular_component	large ribosomal subunit
E	0017148	biological_process	negative regulation of translation
E	0019843	molecular_function	rRNA binding
E	0022625	cellular_component	cytosolic large ribosomal subunit
E	0030371	molecular_function	translation repressor activity
E	0031555	biological_process	transcriptional attenuation
E	0042255	biological_process	ribosome assembly
E	0045892	biological_process	negative regulation of DNA-templated transcription
E	0046677	biological_process	response to antibiotic
E	0048027	molecular_function	mRNA 5'-UTR binding
E	0060698	molecular_function	endoribonuclease inhibitor activity
E	1990904	cellular_component	ribonucleoprotein complex
E	2000766	biological_process	negative regulation of cytoplasmic translation
F	0000049	molecular_function	tRNA binding
F	0002181	biological_process	cytoplasmic translation
F	0003723	molecular_function	RNA binding
F	0003735	molecular_function	structural constituent of ribosome
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0005840	cellular_component	ribosome
F	0006412	biological_process	translation
F	0008097	molecular_function	5S rRNA binding
F	0019843	molecular_function	rRNA binding
F	0022625	cellular_component	cytosolic large ribosomal subunit
F	1990904	cellular_component	ribonucleoprotein complex
J	0002181	biological_process	cytoplasmic translation
J	0003729	molecular_function	mRNA binding
J	0003735	molecular_function	structural constituent of ribosome
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0005840	cellular_component	ribosome
J	0006412	biological_process	translation
J	0008270	molecular_function	zinc ion binding
J	0017148	biological_process	negative regulation of translation
J	0022625	cellular_component	cytosolic large ribosomal subunit
J	0043229	cellular_component	intracellular organelle
J	0048027	molecular_function	mRNA 5'-UTR binding
J	0070180	molecular_function	large ribosomal subunit rRNA binding
J	1990904	cellular_component	ribonucleoprotein complex
L	0002181	biological_process	cytoplasmic translation
L	0003735	molecular_function	structural constituent of ribosome
L	0005515	molecular_function	protein binding
L	0005737	cellular_component	cytoplasm
L	0005840	cellular_component	ribosome
L	0006412	biological_process	translation
L	0015934	cellular_component	large ribosomal subunit
L	0019843	molecular_function	rRNA binding
L	0022625	cellular_component	cytosolic large ribosomal subunit
L	1990904	cellular_component	ribonucleoprotein complex
O	0002181	biological_process	cytoplasmic translation
O	0003735	molecular_function	structural constituent of ribosome
O	0005737	cellular_component	cytoplasm
O	0005829	cellular_component	cytosol
O	0005840	cellular_component	ribosome
O	0006412	biological_process	translation
O	0008097	molecular_function	5S rRNA binding
O	0019843	molecular_function	rRNA binding
O	0022625	cellular_component	cytosolic large ribosomal subunit
O	0043229	cellular_component	intracellular organelle
O	1990904	cellular_component	ribonucleoprotein complex
Q	0000900	molecular_function	mRNA regulatory element binding translation repressor activity
Q	0002181	biological_process	cytoplasmic translation
Q	0003729	molecular_function	mRNA binding
Q	0003735	molecular_function	structural constituent of ribosome
Q	0005737	cellular_component	cytoplasm
Q	0005829	cellular_component	cytosol
Q	0005840	cellular_component	ribosome
Q	0006412	biological_process	translation
Q	0017148	biological_process	negative regulation of translation
Q	0019843	molecular_function	rRNA binding
Q	0022625	cellular_component	cytosolic large ribosomal subunit
Q	0070180	molecular_function	large ribosomal subunit rRNA binding
Q	1990904	cellular_component	ribonucleoprotein complex
R	0002181	biological_process	cytoplasmic translation
R	0003723	molecular_function	RNA binding
R	0003735	molecular_function	structural constituent of ribosome
R	0005737	cellular_component	cytoplasm
R	0005829	cellular_component	cytosol
R	0005840	cellular_component	ribosome
R	0006412	biological_process	translation
R	0019843	molecular_function	rRNA binding
R	0022625	cellular_component	cytosolic large ribosomal subunit
R	0043229	cellular_component	intracellular organelle
R	1990904	cellular_component	ribonucleoprotein complex
S	0002181	biological_process	cytoplasmic translation
S	0003735	molecular_function	structural constituent of ribosome
S	0005515	molecular_function	protein binding
S	0005737	cellular_component	cytoplasm
S	0005829	cellular_component	cytosol
S	0005840	cellular_component	ribosome
S	0006412	biological_process	translation
S	0015934	cellular_component	large ribosomal subunit
S	0019843	molecular_function	rRNA binding
S	0022625	cellular_component	cytosolic large ribosomal subunit
S	0042255	biological_process	ribosome assembly
S	0042256	biological_process	cytosolic ribosome assembly
S	0046677	biological_process	response to antibiotic
S	0070180	molecular_function	large ribosomal subunit rRNA binding
S	1902626	biological_process	assembly of large subunit precursor of preribosome
S	1990904	cellular_component	ribonucleoprotein complex
U	0000027	biological_process	ribosomal large subunit assembly
U	0002181	biological_process	cytoplasmic translation
U	0003723	molecular_function	RNA binding
U	0003735	molecular_function	structural constituent of ribosome
U	0005515	molecular_function	protein binding
U	0005737	cellular_component	cytoplasm
U	0005829	cellular_component	cytosol
U	0005840	cellular_component	ribosome
U	0006412	biological_process	translation
U	0019843	molecular_function	rRNA binding
U	0022625	cellular_component	cytosolic large ribosomal subunit
U	0070180	molecular_function	large ribosomal subunit rRNA binding
U	1990904	cellular_component	ribonucleoprotein complex
V	0000027	biological_process	ribosomal large subunit assembly
V	0002181	biological_process	cytoplasmic translation
V	0003723	molecular_function	RNA binding
V	0003735	molecular_function	structural constituent of ribosome
V	0005737	cellular_component	cytoplasm
V	0005829	cellular_component	cytosol
V	0005840	cellular_component	ribosome
V	0006412	biological_process	translation
V	0008097	molecular_function	5S rRNA binding
V	0009314	biological_process	response to radiation
V	0017148	biological_process	negative regulation of translation
V	0019843	molecular_function	rRNA binding
V	0022625	cellular_component	cytosolic large ribosomal subunit
V	1990904	cellular_component	ribonucleoprotein complex
W	0000027	biological_process	ribosomal large subunit assembly
W	0000049	molecular_function	tRNA binding
W	0001558	biological_process	regulation of cell growth
W	0002181	biological_process	cytoplasmic translation
W	0003735	molecular_function	structural constituent of ribosome
W	0005515	molecular_function	protein binding
W	0005737	cellular_component	cytoplasm
W	0005840	cellular_component	ribosome
W	0006412	biological_process	translation
W	0019843	molecular_function	rRNA binding
W	0022625	cellular_component	cytosolic large ribosomal subunit
W	0042256	biological_process	cytosolic ribosome assembly
W	0043022	molecular_function	ribosome binding
W	0090070	biological_process	positive regulation of ribosome biogenesis
W	1902626	biological_process	assembly of large subunit precursor of preribosome
W	1990904	cellular_component	ribonucleoprotein complex
Y	0000027	biological_process	ribosomal large subunit assembly
Y	0002181	biological_process	cytoplasmic translation
Y	0003735	molecular_function	structural constituent of ribosome
Y	0005737	cellular_component	cytoplasm
Y	0005840	cellular_component	ribosome
Y	0006412	biological_process	translation
Y	0019843	molecular_function	rRNA binding
Y	0022625	cellular_component	cytosolic large ribosomal subunit
Y	1990904	cellular_component	ribonucleoprotein complex
Z	0000027	biological_process	ribosomal large subunit assembly
Z	0002181	biological_process	cytoplasmic translation
Z	0003735	molecular_function	structural constituent of ribosome
Z	0005737	cellular_component	cytoplasm
Z	0005840	cellular_component	ribosome
Z	0006412	biological_process	translation
Z	0015934	cellular_component	large ribosomal subunit
Z	0022625	cellular_component	cytosolic large ribosomal subunit
Z	1990904	cellular_component	ribonucleoprotein complex

Functional Information from PROSITE/UniProt

site_id	PS00358
Number of Residues	17
Details	RIBOSOMAL_L5 Ribosomal protein L5 signature. LaaISGQkpLiTkARkS

Chain	Residue	Details
F	LEU56-SER72

---

site_id	PS00464
Number of Residues	25
Details	RIBOSOMAL_L22 Ribosomal protein L22 signature. KriMpRAkGRadrilkrtSHITVvV

Chain	Residue	Details
S	LYS83-VAL107

---

site_id	PS00475
Number of Residues	31
Details	RIBOSOMAL_L15 Ribosomal protein L15 signature. KVILaGeVttp..VtVrglrVTkgAraaIeaaG

Chain	Residue	Details
L	LYS109-GLY139

---

site_id	PS00579
Number of Residues	15
Details	RIBOSOMAL_L29 Ribosomal protein L29 signature. QSHLLKqVRRDVARV

Chain	Residue	Details
Y	GLN39-VAL53

---

site_id	PS00634
Number of Residues	33
Details	RIBOSOMAL_L30 Ribosomal protein L30 signature. TLlgLgLrRigHtVeredtpairgMInaVsfMV

Chain	Residue	Details
Z	THR22-VAL54

---

site_id	PS00783
Number of Residues	23
Details	RIBOSOMAL_L13 Ribosomal protein L13 signature. VKGMLPkgpl.GRamfrkLkVYaG

Chain	Residue	Details
J	VAL105-GLY127

---

site_id	PS00784
Number of Residues	20
Details	RIBOSOMAL_L34 Ribosomal protein L34 signature. KRTFQpsvlkRnrsh.GFraR

Chain	Residue	Details
2	LYS2-ARG21

---

site_id	PS00831
Number of Residues	15
Details	RIBOSOMAL_L27 Ribosomal protein L27 signature. GsIIvRQRGtkfhaG

Chain	Residue	Details
W	GLY30-GLY44

---

site_id	PS00937
Number of Residues	17
Details	RIBOSOMAL_L20 Ribosomal protein L20 signature. KrqfRqLWIARINaaaR

Chain	Residue	Details
Q	LYS53-ARG69

---

site_id	PS01108
Number of Residues	18
Details	RIBOSOMAL_L24 Ribosomal protein L24 signature. DDeViVLtGkdKGkr.GkV

Chain	Residue	Details
U	ASP7-VAL24

---

site_id	PS01169
Number of Residues	23
Details	RIBOSOMAL_L21 Ribosomal protein L21 signature. VkivKfrrRKhyrkqqGHRQwfT

Chain	Residue	Details
R	VAL72-THR94

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0000269|PubMed:18723842

Chain	Residue	Details
F	LYS2

---