8C7O

Unliganded transcriptional pleiotropic repressor CodY from Staphylococcus aureus

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000976	molecular_function	transcription cis-regulatory region binding
A	0001217	molecular_function	DNA-binding transcription repressor activity
A	0003677	molecular_function	DNA binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0005525	molecular_function	GTP binding
A	0005737	cellular_component	cytoplasm
A	0006355	biological_process	regulation of DNA-templated transcription
A	0032993	cellular_component	protein-DNA complex
A	0045892	biological_process	negative regulation of DNA-templated transcription
B	0000976	molecular_function	transcription cis-regulatory region binding
B	0001217	molecular_function	DNA-binding transcription repressor activity
B	0003677	molecular_function	DNA binding
B	0003700	molecular_function	DNA-binding transcription factor activity
B	0005525	molecular_function	GTP binding
B	0005737	cellular_component	cytoplasm
B	0006355	biological_process	regulation of DNA-templated transcription
B	0032993	cellular_component	protein-DNA complex
B	0045892	biological_process	negative regulation of DNA-templated transcription

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	38
Details	DNA_BIND: H-T-H motif => ECO:0000255|HAMAP-Rule:MF_00621

Chain	Residue	Details
A	ALA203-ARG222
B	ALA203-ARG222

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site_id	SWS_FT_FI2
Number of Residues	22
Details	BINDING: BINDING => ECO:0000269|PubMed:27596595, ECO:0007744|PDB:5EY0, ECO:0007744|PDB:5EY1

Chain	Residue	Details
A	VAL22
A	GLU153
A	LYS158
B	VAL22
B	PHE24
B	SER43
B	ARG44
B	ARG45
B	LYS47
B	ARG61
B	THR96
A	PHE24
B	PHE98
B	GLU153
B	LYS158
A	SER43
A	ARG44
A	ARG45
A	LYS47
A	ARG61
A	THR96
A	PHE98

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