8C6J

Human spliceosomal PM5 C* complex

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
4	0000398	biological_process	mRNA splicing, via spliceosome
4	0003674	molecular_function	molecular_function
4	0005515	molecular_function	protein binding
4	0005634	cellular_component	nucleus
4	0005681	cellular_component	spliceosomal complex
4	0006397	biological_process	mRNA processing
4	0007399	biological_process	nervous system development
4	0008380	biological_process	RNA splicing
4	0071013	cellular_component	catalytic step 2 spliceosome
7	0000184	biological_process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
7	0000398	biological_process	mRNA splicing, via spliceosome
7	0003676	molecular_function	nucleic acid binding
7	0003723	molecular_function	RNA binding
7	0003724	molecular_function	RNA helicase activity
7	0003729	molecular_function	mRNA binding
7	0004386	molecular_function	helicase activity
7	0005515	molecular_function	protein binding
7	0005524	molecular_function	ATP binding
7	0005634	cellular_component	nucleus
7	0005654	cellular_component	nucleoplasm
7	0005681	cellular_component	spliceosomal complex
7	0005730	cellular_component	nucleolus
7	0005737	cellular_component	cytoplasm
7	0005829	cellular_component	cytosol
7	0006364	biological_process	rRNA processing
7	0006397	biological_process	mRNA processing
7	0006406	biological_process	mRNA export from nucleus
7	0006417	biological_process	regulation of translation
7	0008143	molecular_function	poly(A) binding
7	0008306	biological_process	associative learning
7	0008380	biological_process	RNA splicing
7	0010629	biological_process	negative regulation of gene expression
7	0014070	biological_process	response to organic cyclic compound
7	0016020	cellular_component	membrane
7	0016607	cellular_component	nuclear speck
7	0016787	molecular_function	hydrolase activity
7	0016887	molecular_function	ATP hydrolysis activity
7	0017148	biological_process	negative regulation of translation
7	0030425	cellular_component	dendrite
7	0035145	cellular_component	exon-exon junction complex
7	0035368	molecular_function	selenocysteine insertion sequence binding
7	0035613	molecular_function	RNA stem-loop binding
7	0035640	biological_process	exploration behavior
7	0043021	molecular_function	ribonucleoprotein complex binding
7	0043025	cellular_component	neuronal cell body
7	0045727	biological_process	positive regulation of translation
7	0048701	biological_process	embryonic cranial skeleton morphogenesis
7	0051028	biological_process	mRNA transport
7	0071006	cellular_component	U2-type catalytic step 1 spliceosome
7	0071013	cellular_component	catalytic step 2 spliceosome
7	0072715	biological_process	cellular response to selenite ion
7	0090394	biological_process	negative regulation of excitatory postsynaptic potential
7	0098794	cellular_component	postsynapse
7	0098978	cellular_component	glutamatergic synapse
7	0099578	biological_process	regulation of translation at postsynapse, modulating synaptic transmission
7	1904570	biological_process	negative regulation of selenocysteine incorporation
7	1990416	biological_process	cellular response to brain-derived neurotrophic factor stimulus
7	1990904	cellular_component	ribonucleoprotein complex
7	2000622	biological_process	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
8	0000184	biological_process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
8	0000381	biological_process	regulation of alternative mRNA splicing, via spliceosome
8	0000398	biological_process	mRNA splicing, via spliceosome
8	0003676	molecular_function	nucleic acid binding
8	0003723	molecular_function	RNA binding
8	0003729	molecular_function	mRNA binding
8	0005515	molecular_function	protein binding
8	0005634	cellular_component	nucleus
8	0005654	cellular_component	nucleoplasm
8	0005681	cellular_component	spliceosomal complex
8	0005737	cellular_component	cytoplasm
8	0005829	cellular_component	cytosol
8	0006396	biological_process	RNA processing
8	0006397	biological_process	mRNA processing
8	0006406	biological_process	mRNA export from nucleus
8	0006417	biological_process	regulation of translation
8	0008380	biological_process	RNA splicing
8	0016607	cellular_component	nuclear speck
8	0030425	cellular_component	dendrite
8	0035145	cellular_component	exon-exon junction complex
8	0043025	cellular_component	neuronal cell body
8	0050684	biological_process	regulation of mRNA processing
8	0051028	biological_process	mRNA transport
8	0071006	cellular_component	U2-type catalytic step 1 spliceosome
8	0071013	cellular_component	catalytic step 2 spliceosome
8	1990501	cellular_component	exon-exon junction subcomplex mago-y14
8	2000622	biological_process	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
9	0000184	biological_process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
9	0000381	biological_process	regulation of alternative mRNA splicing, via spliceosome
9	0000398	biological_process	mRNA splicing, via spliceosome
9	0003723	molecular_function	RNA binding
9	0005515	molecular_function	protein binding
9	0005634	cellular_component	nucleus
9	0005654	cellular_component	nucleoplasm
9	0005681	cellular_component	spliceosomal complex
9	0005737	cellular_component	cytoplasm
9	0005829	cellular_component	cytosol
9	0006397	biological_process	mRNA processing
9	0006406	biological_process	mRNA export from nucleus
9	0006417	biological_process	regulation of translation
9	0008380	biological_process	RNA splicing
9	0016607	cellular_component	nuclear speck
9	0035145	cellular_component	exon-exon junction complex
9	0050684	biological_process	regulation of mRNA processing
9	0051028	biological_process	mRNA transport
9	0071013	cellular_component	catalytic step 2 spliceosome
9	1990501	cellular_component	exon-exon junction subcomplex mago-y14
9	2000622	biological_process	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
a	0000245	biological_process	spliceosomal complex assembly
a	0000387	biological_process	spliceosomal snRNP assembly
a	0000398	biological_process	mRNA splicing, via spliceosome
a	0003723	molecular_function	RNA binding
a	0005515	molecular_function	protein binding
a	0005634	cellular_component	nucleus
a	0005654	cellular_component	nucleoplasm
a	0005681	cellular_component	spliceosomal complex
a	0005682	cellular_component	U5 snRNP
a	0005684	cellular_component	U2-type spliceosomal complex
a	0005685	cellular_component	U1 snRNP
a	0005686	cellular_component	U2 snRNP
a	0005687	cellular_component	U4 snRNP
a	0005689	cellular_component	U12-type spliceosomal complex
a	0005737	cellular_component	cytoplasm
a	0005829	cellular_component	cytosol
a	0006397	biological_process	mRNA processing
a	0008380	biological_process	RNA splicing
a	0030532	cellular_component	small nuclear ribonucleoprotein complex
a	0034709	cellular_component	methylosome
a	0034715	cellular_component	pICln-Sm protein complex
a	0034719	cellular_component	SMN-Sm protein complex
a	0036261	biological_process	7-methylguanosine cap hypermethylation
a	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
a	0070062	cellular_component	extracellular exosome
a	0071005	cellular_component	U2-type precatalytic spliceosome
a	0071007	cellular_component	U2-type catalytic step 2 spliceosome
a	0071011	cellular_component	precatalytic spliceosome
a	0071013	cellular_component	catalytic step 2 spliceosome
a	1903241	biological_process	U2-type prespliceosome assembly
A	0000244	biological_process	spliceosomal tri-snRNP complex assembly
A	0000375	biological_process	RNA splicing, via transesterification reactions
A	0000398	biological_process	mRNA splicing, via spliceosome
A	0003723	molecular_function	RNA binding
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005681	cellular_component	spliceosomal complex
A	0005682	cellular_component	U5 snRNP
A	0006397	biological_process	mRNA processing
A	0008233	molecular_function	peptidase activity
A	0008237	molecular_function	metallopeptidase activity
A	0008380	biological_process	RNA splicing
A	0016020	cellular_component	membrane
A	0016607	cellular_component	nuclear speck
A	0017070	molecular_function	U6 snRNA binding
A	0030532	cellular_component	small nuclear ribonucleoprotein complex
A	0030619	molecular_function	U1 snRNA binding
A	0030620	molecular_function	U2 snRNA binding
A	0030623	molecular_function	U5 snRNA binding
A	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
A	0070530	molecular_function	K63-linked polyubiquitin modification-dependent protein binding
A	0071005	cellular_component	U2-type precatalytic spliceosome
A	0071006	cellular_component	U2-type catalytic step 1 spliceosome
A	0071007	cellular_component	U2-type catalytic step 2 spliceosome
A	0071013	cellular_component	catalytic step 2 spliceosome
A	0071222	biological_process	cellular response to lipopolysaccharide
A	0071356	biological_process	cellular response to tumor necrosis factor
A	0097157	molecular_function	pre-mRNA intronic binding
A	0140492	molecular_function	metal-dependent deubiquitinase activity
b	0000387	biological_process	spliceosomal snRNP assembly
b	0000398	biological_process	mRNA splicing, via spliceosome
b	0003723	molecular_function	RNA binding
b	0005515	molecular_function	protein binding
b	0005634	cellular_component	nucleus
b	0005654	cellular_component	nucleoplasm
b	0005681	cellular_component	spliceosomal complex
b	0005682	cellular_component	U5 snRNP
b	0005683	cellular_component	U7 snRNP
b	0005684	cellular_component	U2-type spliceosomal complex
b	0005685	cellular_component	U1 snRNP
b	0005686	cellular_component	U2 snRNP
b	0005687	cellular_component	U4 snRNP
b	0005689	cellular_component	U12-type spliceosomal complex
b	0005697	cellular_component	telomerase holoenzyme complex
b	0005737	cellular_component	cytoplasm
b	0005829	cellular_component	cytosol
b	0006397	biological_process	mRNA processing
b	0006479	biological_process	protein methylation
b	0008380	biological_process	RNA splicing
b	0030532	cellular_component	small nuclear ribonucleoprotein complex
b	0034709	cellular_component	methylosome
b	0034719	cellular_component	SMN-Sm protein complex
b	0036261	biological_process	7-methylguanosine cap hypermethylation
b	0043229	cellular_component	intracellular organelle
b	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
b	0070034	molecular_function	telomerase RNA binding
b	0070990	molecular_function	snRNP binding
b	0071004	cellular_component	U2-type prespliceosome
b	0071005	cellular_component	U2-type precatalytic spliceosome
b	0071007	cellular_component	U2-type catalytic step 2 spliceosome
b	0071013	cellular_component	catalytic step 2 spliceosome
b	0071204	cellular_component	histone pre-mRNA 3'end processing complex
b	0071208	molecular_function	histone pre-mRNA DCP binding
b	1903241	biological_process	U2-type prespliceosome assembly
b	1990446	molecular_function	U1 snRNP binding
b	1990447	molecular_function	U2 snRNP binding
B	0000354	biological_process	cis assembly of pre-catalytic spliceosome
B	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
B	0000398	biological_process	mRNA splicing, via spliceosome
B	0001649	biological_process	osteoblast differentiation
B	0003676	molecular_function	nucleic acid binding
B	0003723	molecular_function	RNA binding
B	0003724	molecular_function	RNA helicase activity
B	0004386	molecular_function	helicase activity
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005681	cellular_component	spliceosomal complex
B	0005682	cellular_component	U5 snRNP
B	0006397	biological_process	mRNA processing
B	0008380	biological_process	RNA splicing
B	0016020	cellular_component	membrane
B	0016787	molecular_function	hydrolase activity
B	0016887	molecular_function	ATP hydrolysis activity
B	0042802	molecular_function	identical protein binding
B	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
B	0071005	cellular_component	U2-type precatalytic spliceosome
B	0071006	cellular_component	U2-type catalytic step 1 spliceosome
B	0071013	cellular_component	catalytic step 2 spliceosome
c	0000243	cellular_component	commitment complex
c	0000245	biological_process	spliceosomal complex assembly
c	0000387	biological_process	spliceosomal snRNP assembly
c	0000398	biological_process	mRNA splicing, via spliceosome
c	0003723	molecular_function	RNA binding
c	0005515	molecular_function	protein binding
c	0005634	cellular_component	nucleus
c	0005654	cellular_component	nucleoplasm
c	0005681	cellular_component	spliceosomal complex
c	0005682	cellular_component	U5 snRNP
c	0005684	cellular_component	U2-type spliceosomal complex
c	0005685	cellular_component	U1 snRNP
c	0005686	cellular_component	U2 snRNP
c	0005687	cellular_component	U4 snRNP
c	0005689	cellular_component	U12-type spliceosomal complex
c	0005737	cellular_component	cytoplasm
c	0005829	cellular_component	cytosol
c	0006396	biological_process	RNA processing
c	0006397	biological_process	mRNA processing
c	0008380	biological_process	RNA splicing
c	0030532	cellular_component	small nuclear ribonucleoprotein complex
c	0034709	cellular_component	methylosome
c	0034715	cellular_component	pICln-Sm protein complex
c	0034719	cellular_component	SMN-Sm protein complex
c	0036261	biological_process	7-methylguanosine cap hypermethylation
c	0043229	cellular_component	intracellular organelle
c	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
c	0071005	cellular_component	U2-type precatalytic spliceosome
c	0071007	cellular_component	U2-type catalytic step 2 spliceosome
c	0071011	cellular_component	precatalytic spliceosome
c	0071013	cellular_component	catalytic step 2 spliceosome
c	0097526	cellular_component	spliceosomal tri-snRNP complex
c	1903241	biological_process	U2-type prespliceosome assembly
C	0000398	biological_process	mRNA splicing, via spliceosome
C	0003723	molecular_function	RNA binding
C	0003924	molecular_function	GTPase activity
C	0005515	molecular_function	protein binding
C	0005525	molecular_function	GTP binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005681	cellular_component	spliceosomal complex
C	0005829	cellular_component	cytosol
C	0006397	biological_process	mRNA processing
C	0008380	biological_process	RNA splicing
C	0015030	cellular_component	Cajal body
C	0016020	cellular_component	membrane
C	0016607	cellular_component	nuclear speck
C	0030623	molecular_function	U5 snRNA binding
C	0042220	biological_process	response to cocaine
C	0043231	cellular_component	intracellular membrane-bounded organelle
C	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
C	0071005	cellular_component	U2-type precatalytic spliceosome
C	0071007	cellular_component	U2-type catalytic step 2 spliceosome
C	0071013	cellular_component	catalytic step 2 spliceosome
C	0071466	biological_process	cellular response to xenobiotic stimulus
C3	0000398	biological_process	mRNA splicing, via spliceosome
C3	0000413	biological_process	protein peptidyl-prolyl isomerization
C3	0003755	molecular_function	peptidyl-prolyl cis-trans isomerase activity
C3	0005515	molecular_function	protein binding
C3	0005654	cellular_component	nucleoplasm
C3	0005681	cellular_component	spliceosomal complex
C3	0006397	biological_process	mRNA processing
C3	0006457	biological_process	protein folding
C3	0008380	biological_process	RNA splicing
C3	0071013	cellular_component	catalytic step 2 spliceosome
CD	0000398	biological_process	mRNA splicing, via spliceosome
CD	0003676	molecular_function	nucleic acid binding
CD	0003723	molecular_function	RNA binding
CD	0003724	molecular_function	RNA helicase activity
CD	0003729	molecular_function	mRNA binding
CD	0004386	molecular_function	helicase activity
CD	0005515	molecular_function	protein binding
CD	0005524	molecular_function	ATP binding
CD	0005634	cellular_component	nucleus
CD	0005654	cellular_component	nucleoplasm
CD	0005681	cellular_component	spliceosomal complex
CD	0005829	cellular_component	cytosol
CD	0006397	biological_process	mRNA processing
CD	0006915	biological_process	apoptotic process
CD	0008283	biological_process	cell population proliferation
CD	0008380	biological_process	RNA splicing
CD	0016020	cellular_component	membrane
CD	0016787	molecular_function	hydrolase activity
CD	0016887	molecular_function	ATP hydrolysis activity
CD	0030154	biological_process	cell differentiation
CD	0046872	molecular_function	metal ion binding
CD	0071013	cellular_component	catalytic step 2 spliceosome
CE	0000398	biological_process	mRNA splicing, via spliceosome
CE	0000413	biological_process	protein peptidyl-prolyl isomerization
CE	0003676	molecular_function	nucleic acid binding
CE	0003723	molecular_function	RNA binding
CE	0003729	molecular_function	mRNA binding
CE	0003755	molecular_function	peptidyl-prolyl cis-trans isomerase activity
CE	0005515	molecular_function	protein binding
CE	0005576	cellular_component	extracellular region
CE	0005634	cellular_component	nucleus
CE	0005654	cellular_component	nucleoplasm
CE	0005681	cellular_component	spliceosomal complex
CE	0005737	cellular_component	cytoplasm
CE	0005829	cellular_component	cytosol
CE	0006355	biological_process	regulation of DNA-templated transcription
CE	0006397	biological_process	mRNA processing
CE	0006457	biological_process	protein folding
CE	0008143	molecular_function	poly(A) binding
CE	0008380	biological_process	RNA splicing
CE	0016018	molecular_function	cyclosporin A binding
CE	0016607	cellular_component	nuclear speck
CE	0034774	cellular_component	secretory granule lumen
CE	0043231	cellular_component	intracellular membrane-bounded organelle
CE	0045070	biological_process	positive regulation of viral genome replication
CE	0071007	cellular_component	U2-type catalytic step 2 spliceosome
CE	0071013	cellular_component	catalytic step 2 spliceosome
CE	1904813	cellular_component	ficolin-1-rich granule lumen
CF	0003723	molecular_function	RNA binding
CF	0005515	molecular_function	protein binding
CF	0005634	cellular_component	nucleus
CF	0005654	cellular_component	nucleoplasm
CF	0006325	biological_process	chromatin organization
CF	0006397	biological_process	mRNA processing
CF	0007283	biological_process	spermatogenesis
CF	0008380	biological_process	RNA splicing
CF	0043484	biological_process	regulation of RNA splicing
CI	0000350	biological_process	generation of catalytic spliceosome for second transesterification step
CI	0000389	biological_process	mRNA 3'-splice site recognition
CI	0000398	biological_process	mRNA splicing, via spliceosome
CI	0000974	cellular_component	Prp19 complex
CI	0003723	molecular_function	RNA binding
CI	0005515	molecular_function	protein binding
CI	0005634	cellular_component	nucleus
CI	0005654	cellular_component	nucleoplasm
CI	0005681	cellular_component	spliceosomal complex
CI	0006397	biological_process	mRNA processing
CI	0008380	biological_process	RNA splicing
CI	0071006	cellular_component	U2-type catalytic step 1 spliceosome
CI	0071013	cellular_component	catalytic step 2 spliceosome
CI	0071014	cellular_component	post-mRNA release spliceosomal complex
CI	0071020	cellular_component	post-spliceosomal complex
CN	0000139	cellular_component	Golgi membrane
CN	0003723	molecular_function	RNA binding
CN	0005515	molecular_function	protein binding
CN	0005634	cellular_component	nucleus
CN	0005654	cellular_component	nucleoplasm
CN	0005737	cellular_component	cytoplasm
CN	0005829	cellular_component	cytosol
CN	0016740	molecular_function	transferase activity
CN	0043086	biological_process	negative regulation of catalytic activity
CN	0045428	biological_process	regulation of nitric oxide biosynthetic process
CN	0051001	biological_process	negative regulation of nitric-oxide synthase activity
CN	0061630	molecular_function	ubiquitin protein ligase activity
CN	0140313	molecular_function	molecular sequestering activity
CT	0000398	biological_process	mRNA splicing, via spliceosome
CT	0000775	cellular_component	chromosome, centromeric region
CT	0003723	molecular_function	RNA binding
CT	0005515	molecular_function	protein binding
CT	0005634	cellular_component	nucleus
CT	0005654	cellular_component	nucleoplasm
CT	0005681	cellular_component	spliceosomal complex
CT	0005694	cellular_component	chromosome
CT	0005829	cellular_component	cytosol
CT	0006397	biological_process	mRNA processing
CT	0007059	biological_process	chromosome segregation
CT	0008380	biological_process	RNA splicing
CT	0030623	molecular_function	U5 snRNA binding
CT	0045292	biological_process	mRNA cis splicing, via spliceosome
CT	0060629	biological_process	regulation of homologous chromosome segregation
d	0000243	cellular_component	commitment complex
d	0000387	biological_process	spliceosomal snRNP assembly
d	0000398	biological_process	mRNA splicing, via spliceosome
d	0003723	molecular_function	RNA binding
d	0005515	molecular_function	protein binding
d	0005634	cellular_component	nucleus
d	0005654	cellular_component	nucleoplasm
d	0005681	cellular_component	spliceosomal complex
d	0005682	cellular_component	U5 snRNP
d	0005683	cellular_component	U7 snRNP
d	0005684	cellular_component	U2-type spliceosomal complex
d	0005685	cellular_component	U1 snRNP
d	0005686	cellular_component	U2 snRNP
d	0005687	cellular_component	U4 snRNP
d	0005689	cellular_component	U12-type spliceosomal complex
d	0005697	cellular_component	telomerase holoenzyme complex
d	0005737	cellular_component	cytoplasm
d	0005829	cellular_component	cytosol
d	0006396	biological_process	RNA processing
d	0006397	biological_process	mRNA processing
d	0006479	biological_process	protein methylation
d	0008380	biological_process	RNA splicing
d	0016604	cellular_component	nuclear body
d	0019899	molecular_function	enzyme binding
d	0030532	cellular_component	small nuclear ribonucleoprotein complex
d	0034709	cellular_component	methylosome
d	0034715	cellular_component	pICln-Sm protein complex
d	0034719	cellular_component	SMN-Sm protein complex
d	0036261	biological_process	7-methylguanosine cap hypermethylation
d	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
d	0070034	molecular_function	telomerase RNA binding
d	0071005	cellular_component	U2-type precatalytic spliceosome
d	0071007	cellular_component	U2-type catalytic step 2 spliceosome
d	0071011	cellular_component	precatalytic spliceosome
d	0071013	cellular_component	catalytic step 2 spliceosome
d	0071208	molecular_function	histone pre-mRNA DCP binding
d	0071209	molecular_function	U7 snRNA binding
d	0097526	cellular_component	spliceosomal tri-snRNP complex
d	1903241	biological_process	U2-type prespliceosome assembly
d	1990446	molecular_function	U1 snRNP binding
D	0003014	biological_process	renal system process
D	0003725	molecular_function	double-stranded RNA binding
D	0004860	molecular_function	protein kinase inhibitor activity
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005681	cellular_component	spliceosomal complex
D	0005730	cellular_component	nucleolus
D	0006397	biological_process	mRNA processing
D	0006469	biological_process	negative regulation of protein kinase activity
D	0008380	biological_process	RNA splicing
D	0019901	molecular_function	protein kinase binding
D	0042326	biological_process	negative regulation of phosphorylation
D	0070062	cellular_component	extracellular exosome
e	0000245	biological_process	spliceosomal complex assembly
e	0000387	biological_process	spliceosomal snRNP assembly
e	0000398	biological_process	mRNA splicing, via spliceosome
e	0003723	molecular_function	RNA binding
e	0005515	molecular_function	protein binding
e	0005634	cellular_component	nucleus
e	0005654	cellular_component	nucleoplasm
e	0005681	cellular_component	spliceosomal complex
e	0005682	cellular_component	U5 snRNP
e	0005683	cellular_component	U7 snRNP
e	0005684	cellular_component	U2-type spliceosomal complex
e	0005685	cellular_component	U1 snRNP
e	0005686	cellular_component	U2 snRNP
e	0005687	cellular_component	U4 snRNP
e	0005689	cellular_component	U12-type spliceosomal complex
e	0005697	cellular_component	telomerase holoenzyme complex
e	0005737	cellular_component	cytoplasm
e	0005829	cellular_component	cytosol
e	0006397	biological_process	mRNA processing
e	0008380	biological_process	RNA splicing
e	0030532	cellular_component	small nuclear ribonucleoprotein complex
e	0034709	cellular_component	methylosome
e	0034715	cellular_component	pICln-Sm protein complex
e	0034719	cellular_component	SMN-Sm protein complex
e	0036261	biological_process	7-methylguanosine cap hypermethylation
e	0043229	cellular_component	intracellular organelle
e	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
e	0071005	cellular_component	U2-type precatalytic spliceosome
e	0071007	cellular_component	U2-type catalytic step 2 spliceosome
e	0071011	cellular_component	precatalytic spliceosome
e	0071013	cellular_component	catalytic step 2 spliceosome
e	1903241	biological_process	U2-type prespliceosome assembly
f	0000387	biological_process	spliceosomal snRNP assembly
f	0000398	biological_process	mRNA splicing, via spliceosome
f	0003723	molecular_function	RNA binding
f	0005515	molecular_function	protein binding
f	0005634	cellular_component	nucleus
f	0005654	cellular_component	nucleoplasm
f	0005681	cellular_component	spliceosomal complex
f	0005682	cellular_component	U5 snRNP
f	0005683	cellular_component	U7 snRNP
f	0005684	cellular_component	U2-type spliceosomal complex
f	0005685	cellular_component	U1 snRNP
f	0005686	cellular_component	U2 snRNP
f	0005687	cellular_component	U4 snRNP
f	0005689	cellular_component	U12-type spliceosomal complex
f	0005737	cellular_component	cytoplasm
f	0005829	cellular_component	cytosol
f	0006397	biological_process	mRNA processing
f	0008380	biological_process	RNA splicing
f	0030532	cellular_component	small nuclear ribonucleoprotein complex
f	0034709	cellular_component	methylosome
f	0034715	cellular_component	pICln-Sm protein complex
f	0034719	cellular_component	SMN-Sm protein complex
f	0036261	biological_process	7-methylguanosine cap hypermethylation
f	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
f	0071005	cellular_component	U2-type precatalytic spliceosome
f	0071007	cellular_component	U2-type catalytic step 2 spliceosome
f	0071013	cellular_component	catalytic step 2 spliceosome
f	0120114	cellular_component	Sm-like protein family complex
f	1903241	biological_process	U2-type prespliceosome assembly
F	0000398	biological_process	mRNA splicing, via spliceosome
F	0001933	biological_process	negative regulation of protein phosphorylation
F	0003723	molecular_function	RNA binding
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005654	cellular_component	nucleoplasm
F	0005681	cellular_component	spliceosomal complex
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0006397	biological_process	mRNA processing
F	0008380	biological_process	RNA splicing
F	0016607	cellular_component	nuclear speck
F	0031665	biological_process	negative regulation of lipopolysaccharide-mediated signaling pathway
F	0032088	biological_process	negative regulation of NF-kappaB transcription factor activity
F	0032688	biological_process	negative regulation of interferon-beta production
F	0032717	biological_process	negative regulation of interleukin-8 production
F	0032720	biological_process	negative regulation of tumor necrosis factor production
F	0034122	biological_process	negative regulation of toll-like receptor signaling pathway
F	0043124	biological_process	negative regulation of canonical NF-kappaB signal transduction
F	0045087	biological_process	innate immune response
F	0045292	biological_process	mRNA cis splicing, via spliceosome
F	0045824	biological_process	negative regulation of innate immune response
F	0060339	biological_process	negative regulation of type I interferon-mediated signaling pathway
F	0071013	cellular_component	catalytic step 2 spliceosome
F	0071222	biological_process	cellular response to lipopolysaccharide
F	0071347	biological_process	cellular response to interleukin-1
F	0071356	biological_process	cellular response to tumor necrosis factor
g	0000245	biological_process	spliceosomal complex assembly
g	0000387	biological_process	spliceosomal snRNP assembly
g	0000398	biological_process	mRNA splicing, via spliceosome
g	0003723	molecular_function	RNA binding
g	0005515	molecular_function	protein binding
g	0005634	cellular_component	nucleus
g	0005654	cellular_component	nucleoplasm
g	0005681	cellular_component	spliceosomal complex
g	0005682	cellular_component	U5 snRNP
g	0005683	cellular_component	U7 snRNP
g	0005684	cellular_component	U2-type spliceosomal complex
g	0005685	cellular_component	U1 snRNP
g	0005686	cellular_component	U2 snRNP
g	0005687	cellular_component	U4 snRNP
g	0005689	cellular_component	U12-type spliceosomal complex
g	0005737	cellular_component	cytoplasm
g	0005829	cellular_component	cytosol
g	0006397	biological_process	mRNA processing
g	0008380	biological_process	RNA splicing
g	0030532	cellular_component	small nuclear ribonucleoprotein complex
g	0034709	cellular_component	methylosome
g	0034719	cellular_component	SMN-Sm protein complex
g	0036261	biological_process	7-methylguanosine cap hypermethylation
g	0043186	cellular_component	P granule
g	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
g	0071004	cellular_component	U2-type prespliceosome
g	0071005	cellular_component	U2-type precatalytic spliceosome
g	0071007	cellular_component	U2-type catalytic step 2 spliceosome
g	0071011	cellular_component	precatalytic spliceosome
g	0071013	cellular_component	catalytic step 2 spliceosome
g	0097526	cellular_component	spliceosomal tri-snRNP complex
g	1903241	biological_process	U2-type prespliceosome assembly
G	0003723	molecular_function	RNA binding
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0005730	cellular_component	nucleolus
G	0006915	biological_process	apoptotic process
G	0008150	biological_process	biological_process
h	0000375	biological_process	RNA splicing, via transesterification reactions
h	0000380	biological_process	alternative mRNA splicing, via spliceosome
h	0000386	molecular_function	second spliceosomal transesterification activity
h	0000389	biological_process	mRNA 3'-splice site recognition
h	0000398	biological_process	mRNA splicing, via spliceosome
h	0005515	molecular_function	protein binding
h	0005634	cellular_component	nucleus
h	0005654	cellular_component	nucleoplasm
h	0005681	cellular_component	spliceosomal complex
h	0005737	cellular_component	cytoplasm
h	0005829	cellular_component	cytosol
h	0006397	biological_process	mRNA processing
h	0006886	biological_process	intracellular protein transport
h	0008270	molecular_function	zinc ion binding
h	0008380	biological_process	RNA splicing
h	0016020	cellular_component	membrane
h	0016607	cellular_component	nuclear speck
h	0030532	cellular_component	small nuclear ribonucleoprotein complex
h	0030628	molecular_function	pre-mRNA 3'-splice site binding
h	0034605	biological_process	cellular response to heat
h	0043231	cellular_component	intracellular membrane-bounded organelle
h	0046872	molecular_function	metal ion binding
h	0071013	cellular_component	catalytic step 2 spliceosome
H	0003723	molecular_function	RNA binding
i	0000398	biological_process	mRNA splicing, via spliceosome
i	0000413	biological_process	protein peptidyl-prolyl isomerization
i	0003755	molecular_function	peptidyl-prolyl cis-trans isomerase activity
i	0005515	molecular_function	protein binding
i	0005634	cellular_component	nucleus
i	0005654	cellular_component	nucleoplasm
i	0005681	cellular_component	spliceosomal complex
i	0006397	biological_process	mRNA processing
i	0006457	biological_process	protein folding
i	0008380	biological_process	RNA splicing
i	0016018	molecular_function	cyclosporin A binding
i	0071007	cellular_component	U2-type catalytic step 2 spliceosome
i	0071013	cellular_component	catalytic step 2 spliceosome
i	0097718	molecular_function	disordered domain specific binding
i	1990403	biological_process	embryonic brain development
j	0005515	molecular_function	protein binding
j	0005634	cellular_component	nucleus
j	0005654	cellular_component	nucleoplasm
j	0005737	cellular_component	cytoplasm
j	0005783	cellular_component	endoplasmic reticulum
j	0005789	cellular_component	endoplasmic reticulum membrane
j	0005813	cellular_component	centrosome
j	0006888	biological_process	endoplasmic reticulum to Golgi vesicle-mediated transport
j	0016020	cellular_component	membrane
j	0030674	molecular_function	protein-macromolecule adaptor activity
j	0032527	biological_process	protein exit from endoplasmic reticulum
j	0044297	cellular_component	cell body
j	0090158	biological_process	endoplasmic reticulum membrane organization
J	0000398	biological_process	mRNA splicing, via spliceosome
J	0000974	cellular_component	Prp19 complex
J	0001650	cellular_component	fibrillar center
J	0005515	molecular_function	protein binding
J	0005634	cellular_component	nucleus
J	0005654	cellular_component	nucleoplasm
J	0005662	cellular_component	DNA replication factor A complex
J	0005681	cellular_component	spliceosomal complex
J	0006397	biological_process	mRNA processing
J	0008380	biological_process	RNA splicing
J	0016607	cellular_component	nuclear speck
J	0031965	cellular_component	nuclear membrane
J	0034504	biological_process	protein localization to nucleus
J	0071007	cellular_component	U2-type catalytic step 2 spliceosome
J	0071013	cellular_component	catalytic step 2 spliceosome
J	1900087	biological_process	positive regulation of G1/S transition of mitotic cell cycle
k	0000387	biological_process	spliceosomal snRNP assembly
k	0000398	biological_process	mRNA splicing, via spliceosome
k	0003723	molecular_function	RNA binding
k	0005515	molecular_function	protein binding
k	0005634	cellular_component	nucleus
k	0005654	cellular_component	nucleoplasm
k	0005681	cellular_component	spliceosomal complex
k	0005682	cellular_component	U5 snRNP
k	0005683	cellular_component	U7 snRNP
k	0005684	cellular_component	U2-type spliceosomal complex
k	0005685	cellular_component	U1 snRNP
k	0005686	cellular_component	U2 snRNP
k	0005687	cellular_component	U4 snRNP
k	0005689	cellular_component	U12-type spliceosomal complex
k	0005697	cellular_component	telomerase holoenzyme complex
k	0005737	cellular_component	cytoplasm
k	0005829	cellular_component	cytosol
k	0006397	biological_process	mRNA processing
k	0006479	biological_process	protein methylation
k	0008380	biological_process	RNA splicing
k	0030532	cellular_component	small nuclear ribonucleoprotein complex
k	0034709	cellular_component	methylosome
k	0034719	cellular_component	SMN-Sm protein complex
k	0036261	biological_process	7-methylguanosine cap hypermethylation
k	0043229	cellular_component	intracellular organelle
k	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
k	0070034	molecular_function	telomerase RNA binding
k	0070990	molecular_function	snRNP binding
k	0071004	cellular_component	U2-type prespliceosome
k	0071005	cellular_component	U2-type precatalytic spliceosome
k	0071007	cellular_component	U2-type catalytic step 2 spliceosome
k	0071013	cellular_component	catalytic step 2 spliceosome
k	0071204	cellular_component	histone pre-mRNA 3'end processing complex
k	0071208	molecular_function	histone pre-mRNA DCP binding
k	1903241	biological_process	U2-type prespliceosome assembly
k	1990446	molecular_function	U1 snRNP binding
k	1990447	molecular_function	U2 snRNP binding
K	0000122	biological_process	negative regulation of transcription by RNA polymerase II
K	0000398	biological_process	mRNA splicing, via spliceosome
K	0003713	molecular_function	transcription coactivator activity
K	0003714	molecular_function	transcription corepressor activity
K	0003723	molecular_function	RNA binding
K	0005112	molecular_function	Notch binding
K	0005515	molecular_function	protein binding
K	0005634	cellular_component	nucleus
K	0005654	cellular_component	nucleoplasm
K	0005681	cellular_component	spliceosomal complex
K	0006357	biological_process	regulation of transcription by RNA polymerase II
K	0006397	biological_process	mRNA processing
K	0008024	cellular_component	cyclin/CDK positive transcription elongation factor complex
K	0008380	biological_process	RNA splicing
K	0016363	cellular_component	nuclear matrix
K	0016604	cellular_component	nuclear body
K	0016607	cellular_component	nuclear speck
K	0016922	molecular_function	nuclear receptor binding
K	0019899	molecular_function	enzyme binding
K	0030511	biological_process	positive regulation of transforming growth factor beta receptor signaling pathway
K	0042771	biological_process	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
K	0042809	molecular_function	nuclear vitamin D receptor binding
K	0042974	molecular_function	nuclear retinoic acid receptor binding
K	0043923	biological_process	positive regulation by host of viral transcription
K	0045892	biological_process	negative regulation of DNA-templated transcription
K	0045944	biological_process	positive regulation of transcription by RNA polymerase II
K	0046332	molecular_function	SMAD binding
K	0048026	biological_process	positive regulation of mRNA splicing, via spliceosome
K	0048384	biological_process	retinoic acid receptor signaling pathway
K	0048385	biological_process	regulation of retinoic acid receptor signaling pathway
K	0050681	molecular_function	nuclear androgen receptor binding
K	0050769	biological_process	positive regulation of neurogenesis
K	0070562	biological_process	regulation of vitamin D receptor signaling pathway
K	0070564	biological_process	positive regulation of vitamin D receptor signaling pathway
K	0071007	cellular_component	U2-type catalytic step 2 spliceosome
K	0071013	cellular_component	catalytic step 2 spliceosome
K	0071300	biological_process	cellular response to retinoic acid
l	0000243	cellular_component	commitment complex
l	0000245	biological_process	spliceosomal complex assembly
l	0000387	biological_process	spliceosomal snRNP assembly
l	0000398	biological_process	mRNA splicing, via spliceosome
l	0003723	molecular_function	RNA binding
l	0005515	molecular_function	protein binding
l	0005634	cellular_component	nucleus
l	0005654	cellular_component	nucleoplasm
l	0005681	cellular_component	spliceosomal complex
l	0005682	cellular_component	U5 snRNP
l	0005684	cellular_component	U2-type spliceosomal complex
l	0005685	cellular_component	U1 snRNP
l	0005686	cellular_component	U2 snRNP
l	0005687	cellular_component	U4 snRNP
l	0005689	cellular_component	U12-type spliceosomal complex
l	0005737	cellular_component	cytoplasm
l	0005829	cellular_component	cytosol
l	0006396	biological_process	RNA processing
l	0006397	biological_process	mRNA processing
l	0008380	biological_process	RNA splicing
l	0030532	cellular_component	small nuclear ribonucleoprotein complex
l	0034709	cellular_component	methylosome
l	0034715	cellular_component	pICln-Sm protein complex
l	0034719	cellular_component	SMN-Sm protein complex
l	0036261	biological_process	7-methylguanosine cap hypermethylation
l	0043229	cellular_component	intracellular organelle
l	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
l	0071005	cellular_component	U2-type precatalytic spliceosome
l	0071007	cellular_component	U2-type catalytic step 2 spliceosome
l	0071011	cellular_component	precatalytic spliceosome
l	0071013	cellular_component	catalytic step 2 spliceosome
l	0097526	cellular_component	spliceosomal tri-snRNP complex
l	1903241	biological_process	U2-type prespliceosome assembly
L	0000398	biological_process	mRNA splicing, via spliceosome
L	0000785	cellular_component	chromatin
L	0005515	molecular_function	protein binding
L	0005634	cellular_component	nucleus
L	0005654	cellular_component	nucleoplasm
L	0005681	cellular_component	spliceosomal complex
L	0006397	biological_process	mRNA processing
L	0008380	biological_process	RNA splicing
L	0016922	molecular_function	nuclear receptor binding
L	0030374	molecular_function	nuclear receptor coactivator activity
L	0045893	biological_process	positive regulation of DNA-templated transcription
L	0071007	cellular_component	U2-type catalytic step 2 spliceosome
L	2000825	biological_process	positive regulation of androgen receptor activity
m	0000245	biological_process	spliceosomal complex assembly
m	0000387	biological_process	spliceosomal snRNP assembly
m	0000398	biological_process	mRNA splicing, via spliceosome
m	0003723	molecular_function	RNA binding
m	0005515	molecular_function	protein binding
m	0005634	cellular_component	nucleus
m	0005654	cellular_component	nucleoplasm
m	0005681	cellular_component	spliceosomal complex
m	0005682	cellular_component	U5 snRNP
m	0005684	cellular_component	U2-type spliceosomal complex
m	0005685	cellular_component	U1 snRNP
m	0005686	cellular_component	U2 snRNP
m	0005687	cellular_component	U4 snRNP
m	0005689	cellular_component	U12-type spliceosomal complex
m	0005737	cellular_component	cytoplasm
m	0005829	cellular_component	cytosol
m	0006397	biological_process	mRNA processing
m	0008380	biological_process	RNA splicing
m	0030532	cellular_component	small nuclear ribonucleoprotein complex
m	0034709	cellular_component	methylosome
m	0034715	cellular_component	pICln-Sm protein complex
m	0034719	cellular_component	SMN-Sm protein complex
m	0036261	biological_process	7-methylguanosine cap hypermethylation
m	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
m	0070062	cellular_component	extracellular exosome
m	0071005	cellular_component	U2-type precatalytic spliceosome
m	0071007	cellular_component	U2-type catalytic step 2 spliceosome
m	0071011	cellular_component	precatalytic spliceosome
m	0071013	cellular_component	catalytic step 2 spliceosome
m	1903241	biological_process	U2-type prespliceosome assembly
M	0000398	biological_process	mRNA splicing, via spliceosome
M	0000974	cellular_component	Prp19 complex
M	0003676	molecular_function	nucleic acid binding
M	0003723	molecular_function	RNA binding
M	0005515	molecular_function	protein binding
M	0005634	cellular_component	nucleus
M	0005654	cellular_component	nucleoplasm
M	0005681	cellular_component	spliceosomal complex
M	0005737	cellular_component	cytoplasm
M	0006397	biological_process	mRNA processing
M	0008380	biological_process	RNA splicing
M	0017070	molecular_function	U6 snRNA binding
M	0033120	biological_process	positive regulation of RNA splicing
M	0036002	molecular_function	pre-mRNA binding
M	0042307	biological_process	positive regulation of protein import into nucleus
M	0045292	biological_process	mRNA cis splicing, via spliceosome
M	0046827	biological_process	positive regulation of protein export from nucleus
M	0046872	molecular_function	metal ion binding
M	0048306	molecular_function	calcium-dependent protein binding
M	0071006	cellular_component	U2-type catalytic step 1 spliceosome
M	0071007	cellular_component	U2-type catalytic step 2 spliceosome
M	0071013	cellular_component	catalytic step 2 spliceosome
M	0071466	biological_process	cellular response to xenobiotic stimulus
n	0000243	cellular_component	commitment complex
n	0000387	biological_process	spliceosomal snRNP assembly
n	0000398	biological_process	mRNA splicing, via spliceosome
n	0003723	molecular_function	RNA binding
n	0005515	molecular_function	protein binding
n	0005634	cellular_component	nucleus
n	0005654	cellular_component	nucleoplasm
n	0005681	cellular_component	spliceosomal complex
n	0005682	cellular_component	U5 snRNP
n	0005683	cellular_component	U7 snRNP
n	0005684	cellular_component	U2-type spliceosomal complex
n	0005685	cellular_component	U1 snRNP
n	0005686	cellular_component	U2 snRNP
n	0005687	cellular_component	U4 snRNP
n	0005689	cellular_component	U12-type spliceosomal complex
n	0005697	cellular_component	telomerase holoenzyme complex
n	0005737	cellular_component	cytoplasm
n	0005829	cellular_component	cytosol
n	0006396	biological_process	RNA processing
n	0006397	biological_process	mRNA processing
n	0006479	biological_process	protein methylation
n	0008380	biological_process	RNA splicing
n	0016604	cellular_component	nuclear body
n	0019899	molecular_function	enzyme binding
n	0030532	cellular_component	small nuclear ribonucleoprotein complex
n	0034709	cellular_component	methylosome
n	0034715	cellular_component	pICln-Sm protein complex
n	0034719	cellular_component	SMN-Sm protein complex
n	0036261	biological_process	7-methylguanosine cap hypermethylation
n	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
n	0070034	molecular_function	telomerase RNA binding
n	0071005	cellular_component	U2-type precatalytic spliceosome
n	0071007	cellular_component	U2-type catalytic step 2 spliceosome
n	0071011	cellular_component	precatalytic spliceosome
n	0071013	cellular_component	catalytic step 2 spliceosome
n	0071208	molecular_function	histone pre-mRNA DCP binding
n	0071209	molecular_function	U7 snRNA binding
n	0097526	cellular_component	spliceosomal tri-snRNP complex
n	1903241	biological_process	U2-type prespliceosome assembly
n	1990446	molecular_function	U1 snRNP binding
N	0000375	biological_process	RNA splicing, via transesterification reactions
N	0000398	biological_process	mRNA splicing, via spliceosome
N	0003723	molecular_function	RNA binding
N	0005515	molecular_function	protein binding
N	0005634	cellular_component	nucleus
N	0005654	cellular_component	nucleoplasm
N	0005681	cellular_component	spliceosomal complex
N	0005682	cellular_component	U5 snRNP
N	0005732	cellular_component	sno(s)RNA-containing ribonucleoprotein complex
N	0005829	cellular_component	cytosol
N	0006396	biological_process	RNA processing
N	0006397	biological_process	mRNA processing
N	0008380	biological_process	RNA splicing
N	0016607	cellular_component	nuclear speck
N	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
N	0071007	cellular_component	U2-type catalytic step 2 spliceosome
N	0071013	cellular_component	catalytic step 2 spliceosome
o	0000398	biological_process	mRNA splicing, via spliceosome
o	0003723	molecular_function	RNA binding
o	0003729	molecular_function	mRNA binding
o	0005515	molecular_function	protein binding
o	0005634	cellular_component	nucleus
o	0005654	cellular_component	nucleoplasm
o	0005681	cellular_component	spliceosomal complex
o	0006397	biological_process	mRNA processing
o	0008380	biological_process	RNA splicing
o	0016607	cellular_component	nuclear speck
o	0071007	cellular_component	U2-type catalytic step 2 spliceosome
o	0071013	cellular_component	catalytic step 2 spliceosome
o	1990403	biological_process	embryonic brain development
O	0000077	biological_process	DNA damage checkpoint signaling
O	0000398	biological_process	mRNA splicing, via spliceosome
O	0000974	cellular_component	Prp19 complex
O	0000977	molecular_function	RNA polymerase II transcription regulatory region sequence-specific DNA binding
O	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
O	0001228	molecular_function	DNA-binding transcription activator activity, RNA polymerase II-specific
O	0003677	molecular_function	DNA binding
O	0003723	molecular_function	RNA binding
O	0005515	molecular_function	protein binding
O	0005634	cellular_component	nucleus
O	0005654	cellular_component	nucleoplasm
O	0005662	cellular_component	DNA replication factor A complex
O	0005681	cellular_component	spliceosomal complex
O	0005737	cellular_component	cytoplasm
O	0006281	biological_process	DNA repair
O	0006357	biological_process	regulation of transcription by RNA polymerase II
O	0006397	biological_process	mRNA processing
O	0008380	biological_process	RNA splicing
O	0016020	cellular_component	membrane
O	0016607	cellular_component	nuclear speck
O	0042802	molecular_function	identical protein binding
O	0045944	biological_process	positive regulation of transcription by RNA polymerase II
O	0071007	cellular_component	U2-type catalytic step 2 spliceosome
O	0071013	cellular_component	catalytic step 2 spliceosome
O	0071987	molecular_function	WD40-repeat domain binding
p	0000245	biological_process	spliceosomal complex assembly
p	0000387	biological_process	spliceosomal snRNP assembly
p	0000398	biological_process	mRNA splicing, via spliceosome
p	0003723	molecular_function	RNA binding
p	0005515	molecular_function	protein binding
p	0005634	cellular_component	nucleus
p	0005654	cellular_component	nucleoplasm
p	0005681	cellular_component	spliceosomal complex
p	0005682	cellular_component	U5 snRNP
p	0005683	cellular_component	U7 snRNP
p	0005684	cellular_component	U2-type spliceosomal complex
p	0005685	cellular_component	U1 snRNP
p	0005686	cellular_component	U2 snRNP
p	0005687	cellular_component	U4 snRNP
p	0005689	cellular_component	U12-type spliceosomal complex
p	0005697	cellular_component	telomerase holoenzyme complex
p	0005737	cellular_component	cytoplasm
p	0005829	cellular_component	cytosol
p	0006397	biological_process	mRNA processing
p	0008380	biological_process	RNA splicing
p	0030532	cellular_component	small nuclear ribonucleoprotein complex
p	0034709	cellular_component	methylosome
p	0034715	cellular_component	pICln-Sm protein complex
p	0034719	cellular_component	SMN-Sm protein complex
p	0036261	biological_process	7-methylguanosine cap hypermethylation
p	0043229	cellular_component	intracellular organelle
p	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
p	0071005	cellular_component	U2-type precatalytic spliceosome
p	0071007	cellular_component	U2-type catalytic step 2 spliceosome
p	0071011	cellular_component	precatalytic spliceosome
p	0071013	cellular_component	catalytic step 2 spliceosome
p	1903241	biological_process	U2-type prespliceosome assembly
P	0000398	biological_process	mRNA splicing, via spliceosome
P	0000974	cellular_component	Prp19 complex
P	0003723	molecular_function	RNA binding
P	0005515	molecular_function	protein binding
P	0005634	cellular_component	nucleus
P	0005654	cellular_component	nucleoplasm
P	0005681	cellular_component	spliceosomal complex
P	0005739	cellular_component	mitochondrion
P	0006397	biological_process	mRNA processing
P	0008380	biological_process	RNA splicing
P	0016607	cellular_component	nuclear speck
P	0045292	biological_process	mRNA cis splicing, via spliceosome
P	0071007	cellular_component	U2-type catalytic step 2 spliceosome
P	0071013	cellular_component	catalytic step 2 spliceosome
q	0000387	biological_process	spliceosomal snRNP assembly
q	0000398	biological_process	mRNA splicing, via spliceosome
q	0003723	molecular_function	RNA binding
q	0005515	molecular_function	protein binding
q	0005634	cellular_component	nucleus
q	0005654	cellular_component	nucleoplasm
q	0005681	cellular_component	spliceosomal complex
q	0005682	cellular_component	U5 snRNP
q	0005683	cellular_component	U7 snRNP
q	0005684	cellular_component	U2-type spliceosomal complex
q	0005685	cellular_component	U1 snRNP
q	0005686	cellular_component	U2 snRNP
q	0005687	cellular_component	U4 snRNP
q	0005689	cellular_component	U12-type spliceosomal complex
q	0005737	cellular_component	cytoplasm
q	0005829	cellular_component	cytosol
q	0006397	biological_process	mRNA processing
q	0008380	biological_process	RNA splicing
q	0030532	cellular_component	small nuclear ribonucleoprotein complex
q	0034709	cellular_component	methylosome
q	0034715	cellular_component	pICln-Sm protein complex
q	0034719	cellular_component	SMN-Sm protein complex
q	0036261	biological_process	7-methylguanosine cap hypermethylation
q	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
q	0071005	cellular_component	U2-type precatalytic spliceosome
q	0071007	cellular_component	U2-type catalytic step 2 spliceosome
q	0071013	cellular_component	catalytic step 2 spliceosome
q	0120114	cellular_component	Sm-like protein family complex
q	1903241	biological_process	U2-type prespliceosome assembly
r	0000245	biological_process	spliceosomal complex assembly
r	0000387	biological_process	spliceosomal snRNP assembly
r	0000398	biological_process	mRNA splicing, via spliceosome
r	0003723	molecular_function	RNA binding
r	0005515	molecular_function	protein binding
r	0005634	cellular_component	nucleus
r	0005654	cellular_component	nucleoplasm
r	0005681	cellular_component	spliceosomal complex
r	0005682	cellular_component	U5 snRNP
r	0005683	cellular_component	U7 snRNP
r	0005684	cellular_component	U2-type spliceosomal complex
r	0005685	cellular_component	U1 snRNP
r	0005686	cellular_component	U2 snRNP
r	0005687	cellular_component	U4 snRNP
r	0005689	cellular_component	U12-type spliceosomal complex
r	0005737	cellular_component	cytoplasm
r	0005829	cellular_component	cytosol
r	0006397	biological_process	mRNA processing
r	0008380	biological_process	RNA splicing
r	0030532	cellular_component	small nuclear ribonucleoprotein complex
r	0034709	cellular_component	methylosome
r	0034719	cellular_component	SMN-Sm protein complex
r	0036261	biological_process	7-methylguanosine cap hypermethylation
r	0043186	cellular_component	P granule
r	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
r	0071004	cellular_component	U2-type prespliceosome
r	0071005	cellular_component	U2-type precatalytic spliceosome
r	0071007	cellular_component	U2-type catalytic step 2 spliceosome
r	0071011	cellular_component	precatalytic spliceosome
r	0071013	cellular_component	catalytic step 2 spliceosome
r	0097526	cellular_component	spliceosomal tri-snRNP complex
r	1903241	biological_process	U2-type prespliceosome assembly
R	0000398	biological_process	mRNA splicing, via spliceosome
R	0003723	molecular_function	RNA binding
R	0003729	molecular_function	mRNA binding
R	0005515	molecular_function	protein binding
R	0005634	cellular_component	nucleus
R	0005654	cellular_component	nucleoplasm
R	0005681	cellular_component	spliceosomal complex
R	0006397	biological_process	mRNA processing
R	0008380	biological_process	RNA splicing
R	0015030	cellular_component	Cajal body
R	0016607	cellular_component	nuclear speck
R	0070742	molecular_function	C2H2 zinc finger domain binding
R	0071005	cellular_component	U2-type precatalytic spliceosome
R	0071007	cellular_component	U2-type catalytic step 2 spliceosome
R	0071013	cellular_component	catalytic step 2 spliceosome
s	0000375	biological_process	RNA splicing, via transesterification reactions
s	0000398	biological_process	mRNA splicing, via spliceosome
s	0000974	cellular_component	Prp19 complex
s	0005515	molecular_function	protein binding
s	0005634	cellular_component	nucleus
s	0005654	cellular_component	nucleoplasm
s	0005662	cellular_component	DNA replication factor A complex
s	0005681	cellular_component	spliceosomal complex
s	0005730	cellular_component	nucleolus
s	0005813	cellular_component	centrosome
s	0006397	biological_process	mRNA processing
s	0008380	biological_process	RNA splicing
s	0016607	cellular_component	nuclear speck
s	0071007	cellular_component	U2-type catalytic step 2 spliceosome
s	0071013	cellular_component	catalytic step 2 spliceosome
S	0000398	biological_process	mRNA splicing, via spliceosome
S	0006396	biological_process	RNA processing
t	0000077	biological_process	DNA damage checkpoint signaling
t	0000209	biological_process	protein polyubiquitination
t	0000244	biological_process	spliceosomal tri-snRNP complex assembly
t	0000245	biological_process	spliceosomal complex assembly
t	0000398	biological_process	mRNA splicing, via spliceosome
t	0000974	cellular_component	Prp19 complex
t	0004842	molecular_function	ubiquitin-protein transferase activity
t	0005515	molecular_function	protein binding
t	0005634	cellular_component	nucleus
t	0005654	cellular_component	nucleoplasm
t	0005662	cellular_component	DNA replication factor A complex
t	0005681	cellular_component	spliceosomal complex
t	0005737	cellular_component	cytoplasm
t	0005811	cellular_component	lipid droplet
t	0005819	cellular_component	spindle
t	0005856	cellular_component	cytoskeleton
t	0006281	biological_process	DNA repair
t	0006303	biological_process	double-strand break repair via nonhomologous end joining
t	0006397	biological_process	mRNA processing
t	0008104	biological_process	protein localization
t	0008380	biological_process	RNA splicing
t	0008610	biological_process	lipid biosynthetic process
t	0010498	biological_process	proteasomal protein catabolic process
t	0016020	cellular_component	membrane
t	0016567	biological_process	protein ubiquitination
t	0016607	cellular_component	nuclear speck
t	0016740	molecular_function	transferase activity
t	0034450	molecular_function	ubiquitin-ubiquitin ligase activity
t	0035861	cellular_component	site of double-strand break
t	0042802	molecular_function	identical protein binding
t	0048026	biological_process	positive regulation of mRNA splicing, via spliceosome
t	0061630	molecular_function	ubiquitin protein ligase activity
t	0070534	biological_process	protein K63-linked ubiquitination
t	0071006	cellular_component	U2-type catalytic step 1 spliceosome
t	0071007	cellular_component	U2-type catalytic step 2 spliceosome
t	0071013	cellular_component	catalytic step 2 spliceosome
T	0000349	biological_process	generation of catalytic spliceosome for first transesterification step
T	0000398	biological_process	mRNA splicing, via spliceosome
T	0000974	cellular_component	Prp19 complex
T	0001824	biological_process	blastocyst development
T	0005515	molecular_function	protein binding
T	0005634	cellular_component	nucleus
T	0005654	cellular_component	nucleoplasm
T	0005681	cellular_component	spliceosomal complex
T	0006281	biological_process	DNA repair
T	0006283	biological_process	transcription-coupled nucleotide-excision repair
T	0006351	biological_process	DNA-templated transcription
T	0006396	biological_process	RNA processing
T	0006397	biological_process	mRNA processing
T	0008380	biological_process	RNA splicing
T	0016020	cellular_component	membrane
T	0043231	cellular_component	intracellular membrane-bounded organelle
T	0071007	cellular_component	U2-type catalytic step 2 spliceosome
T	0071013	cellular_component	catalytic step 2 spliceosome
T	0071014	cellular_component	post-mRNA release spliceosomal complex
u	0000077	biological_process	DNA damage checkpoint signaling
u	0000209	biological_process	protein polyubiquitination
u	0000244	biological_process	spliceosomal tri-snRNP complex assembly
u	0000245	biological_process	spliceosomal complex assembly
u	0000398	biological_process	mRNA splicing, via spliceosome
u	0000974	cellular_component	Prp19 complex
u	0004842	molecular_function	ubiquitin-protein transferase activity
u	0005515	molecular_function	protein binding
u	0005634	cellular_component	nucleus
u	0005654	cellular_component	nucleoplasm
u	0005662	cellular_component	DNA replication factor A complex
u	0005681	cellular_component	spliceosomal complex
u	0005737	cellular_component	cytoplasm
u	0005811	cellular_component	lipid droplet
u	0005819	cellular_component	spindle
u	0005856	cellular_component	cytoskeleton
u	0006281	biological_process	DNA repair
u	0006303	biological_process	double-strand break repair via nonhomologous end joining
u	0006397	biological_process	mRNA processing
u	0008104	biological_process	protein localization
u	0008380	biological_process	RNA splicing
u	0008610	biological_process	lipid biosynthetic process
u	0010498	biological_process	proteasomal protein catabolic process
u	0016020	cellular_component	membrane
u	0016567	biological_process	protein ubiquitination
u	0016607	cellular_component	nuclear speck
u	0016740	molecular_function	transferase activity
u	0034450	molecular_function	ubiquitin-ubiquitin ligase activity
u	0035861	cellular_component	site of double-strand break
u	0042802	molecular_function	identical protein binding
u	0048026	biological_process	positive regulation of mRNA splicing, via spliceosome
u	0061630	molecular_function	ubiquitin protein ligase activity
u	0070534	biological_process	protein K63-linked ubiquitination
u	0071006	cellular_component	U2-type catalytic step 1 spliceosome
u	0071007	cellular_component	U2-type catalytic step 2 spliceosome
u	0071013	cellular_component	catalytic step 2 spliceosome
U	0000398	biological_process	mRNA splicing, via spliceosome
U	0003723	molecular_function	RNA binding
U	0003724	molecular_function	RNA helicase activity
U	0003727	molecular_function	single-stranded RNA binding
U	0003729	molecular_function	mRNA binding
U	0004386	molecular_function	helicase activity
U	0005515	molecular_function	protein binding
U	0005524	molecular_function	ATP binding
U	0005634	cellular_component	nucleus
U	0005654	cellular_component	nucleoplasm
U	0005681	cellular_component	spliceosomal complex
U	0006397	biological_process	mRNA processing
U	0008380	biological_process	RNA splicing
U	0016020	cellular_component	membrane
U	0016787	molecular_function	hydrolase activity
U	0016887	molecular_function	ATP hydrolysis activity
U	0034458	molecular_function	3'-5' RNA helicase activity
U	0071007	cellular_component	U2-type catalytic step 2 spliceosome
U	0071013	cellular_component	catalytic step 2 spliceosome
v	0000077	biological_process	DNA damage checkpoint signaling
v	0000209	biological_process	protein polyubiquitination
v	0000244	biological_process	spliceosomal tri-snRNP complex assembly
v	0000245	biological_process	spliceosomal complex assembly
v	0000398	biological_process	mRNA splicing, via spliceosome
v	0000974	cellular_component	Prp19 complex
v	0004842	molecular_function	ubiquitin-protein transferase activity
v	0005515	molecular_function	protein binding
v	0005634	cellular_component	nucleus
v	0005654	cellular_component	nucleoplasm
v	0005662	cellular_component	DNA replication factor A complex
v	0005681	cellular_component	spliceosomal complex
v	0005737	cellular_component	cytoplasm
v	0005811	cellular_component	lipid droplet
v	0005819	cellular_component	spindle
v	0005856	cellular_component	cytoskeleton
v	0006281	biological_process	DNA repair
v	0006303	biological_process	double-strand break repair via nonhomologous end joining
v	0006397	biological_process	mRNA processing
v	0008104	biological_process	protein localization
v	0008380	biological_process	RNA splicing
v	0008610	biological_process	lipid biosynthetic process
v	0010498	biological_process	proteasomal protein catabolic process
v	0016020	cellular_component	membrane
v	0016567	biological_process	protein ubiquitination
v	0016607	cellular_component	nuclear speck
v	0016740	molecular_function	transferase activity
v	0034450	molecular_function	ubiquitin-ubiquitin ligase activity
v	0035861	cellular_component	site of double-strand break
v	0042802	molecular_function	identical protein binding
v	0048026	biological_process	positive regulation of mRNA splicing, via spliceosome
v	0061630	molecular_function	ubiquitin protein ligase activity
v	0070534	biological_process	protein K63-linked ubiquitination
v	0071006	cellular_component	U2-type catalytic step 1 spliceosome
v	0071007	cellular_component	U2-type catalytic step 2 spliceosome
v	0071013	cellular_component	catalytic step 2 spliceosome
V	0000390	biological_process	spliceosomal complex disassembly
V	0000398	biological_process	mRNA splicing, via spliceosome
V	0003676	molecular_function	nucleic acid binding
V	0003723	molecular_function	RNA binding
V	0003724	molecular_function	RNA helicase activity
V	0004386	molecular_function	helicase activity
V	0005515	molecular_function	protein binding
V	0005524	molecular_function	ATP binding
V	0005634	cellular_component	nucleus
V	0005654	cellular_component	nucleoplasm
V	0005681	cellular_component	spliceosomal complex
V	0005829	cellular_component	cytosol
V	0006396	biological_process	RNA processing
V	0006397	biological_process	mRNA processing
V	0008186	molecular_function	ATP-dependent activity, acting on RNA
V	0008380	biological_process	RNA splicing
V	0016604	cellular_component	nuclear body
V	0016787	molecular_function	hydrolase activity
V	0016887	molecular_function	ATP hydrolysis activity
V	0042802	molecular_function	identical protein binding
V	0071007	cellular_component	U2-type catalytic step 2 spliceosome
V	0071013	cellular_component	catalytic step 2 spliceosome
w	0000077	biological_process	DNA damage checkpoint signaling
w	0000209	biological_process	protein polyubiquitination
w	0000244	biological_process	spliceosomal tri-snRNP complex assembly
w	0000245	biological_process	spliceosomal complex assembly
w	0000398	biological_process	mRNA splicing, via spliceosome
w	0000974	cellular_component	Prp19 complex
w	0004842	molecular_function	ubiquitin-protein transferase activity
w	0005515	molecular_function	protein binding
w	0005634	cellular_component	nucleus
w	0005654	cellular_component	nucleoplasm
w	0005662	cellular_component	DNA replication factor A complex
w	0005681	cellular_component	spliceosomal complex
w	0005737	cellular_component	cytoplasm
w	0005811	cellular_component	lipid droplet
w	0005819	cellular_component	spindle
w	0005856	cellular_component	cytoskeleton
w	0006281	biological_process	DNA repair
w	0006303	biological_process	double-strand break repair via nonhomologous end joining
w	0006397	biological_process	mRNA processing
w	0008104	biological_process	protein localization
w	0008380	biological_process	RNA splicing
w	0008610	biological_process	lipid biosynthetic process
w	0010498	biological_process	proteasomal protein catabolic process
w	0016020	cellular_component	membrane
w	0016567	biological_process	protein ubiquitination
w	0016607	cellular_component	nuclear speck
w	0016740	molecular_function	transferase activity
w	0034450	molecular_function	ubiquitin-ubiquitin ligase activity
w	0035861	cellular_component	site of double-strand break
w	0042802	molecular_function	identical protein binding
w	0048026	biological_process	positive regulation of mRNA splicing, via spliceosome
w	0061630	molecular_function	ubiquitin protein ligase activity
w	0070534	biological_process	protein K63-linked ubiquitination
w	0071006	cellular_component	U2-type catalytic step 1 spliceosome
w	0071007	cellular_component	U2-type catalytic step 2 spliceosome
w	0071013	cellular_component	catalytic step 2 spliceosome
W	0000398	biological_process	mRNA splicing, via spliceosome
W	0003723	molecular_function	RNA binding
W	0005515	molecular_function	protein binding
W	0005634	cellular_component	nucleus
W	0005654	cellular_component	nucleoplasm
W	0005681	cellular_component	spliceosomal complex
W	0005684	cellular_component	U2-type spliceosomal complex
W	0005686	cellular_component	U2 snRNP
W	0006397	biological_process	mRNA processing
W	0007283	biological_process	spermatogenesis
W	0008380	biological_process	RNA splicing
W	0016604	cellular_component	nuclear body
W	0016607	cellular_component	nuclear speck
W	0030532	cellular_component	small nuclear ribonucleoprotein complex
W	0030620	molecular_function	U2 snRNA binding
W	0071005	cellular_component	U2-type precatalytic spliceosome
W	0071007	cellular_component	U2-type catalytic step 2 spliceosome
W	0071013	cellular_component	catalytic step 2 spliceosome
W	1903241	biological_process	U2-type prespliceosome assembly
y	0000398	biological_process	mRNA splicing, via spliceosome
y	0000974	cellular_component	Prp19 complex
y	0001701	biological_process	in utero embryonic development
y	0003723	molecular_function	RNA binding
y	0005515	molecular_function	protein binding
y	0005634	cellular_component	nucleus
y	0005654	cellular_component	nucleoplasm
y	0005681	cellular_component	spliceosomal complex
y	0006397	biological_process	mRNA processing
y	0007095	biological_process	mitotic G2 DNA damage checkpoint signaling
y	0007369	biological_process	gastrulation
y	0008284	biological_process	positive regulation of cell population proliferation
y	0008380	biological_process	RNA splicing
y	0016607	cellular_component	nuclear speck
y	0048568	biological_process	embryonic organ development
y	0071007	cellular_component	U2-type catalytic step 2 spliceosome
y	0071013	cellular_component	catalytic step 2 spliceosome
y	0071014	cellular_component	post-mRNA release spliceosomal complex
Y	0000398	biological_process	mRNA splicing, via spliceosome
Y	0001650	cellular_component	fibrillar center
Y	0003676	molecular_function	nucleic acid binding
Y	0003723	molecular_function	RNA binding
Y	0005515	molecular_function	protein binding
Y	0005634	cellular_component	nucleus
Y	0005654	cellular_component	nucleoplasm
Y	0005681	cellular_component	spliceosomal complex
Y	0005684	cellular_component	U2-type spliceosomal complex
Y	0005685	cellular_component	U1 snRNP
Y	0005686	cellular_component	U2 snRNP
Y	0006397	biological_process	mRNA processing
Y	0008380	biological_process	RNA splicing
Y	0016607	cellular_component	nuclear speck
Y	0030619	molecular_function	U1 snRNA binding
Y	0036464	cellular_component	cytoplasmic ribonucleoprotein granule
Y	0071005	cellular_component	U2-type precatalytic spliceosome
Y	0071007	cellular_component	U2-type catalytic step 2 spliceosome
Y	0071013	cellular_component	catalytic step 2 spliceosome
Y	1903241	biological_process	U2-type prespliceosome assembly
z	0000479	biological_process	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
z	0003677	molecular_function	DNA binding
z	0003684	molecular_function	damaged DNA binding
z	0003723	molecular_function	RNA binding
z	0005515	molecular_function	protein binding
z	0005634	cellular_component	nucleus
z	0005654	cellular_component	nucleoplasm
z	0005737	cellular_component	cytoplasm
z	0005794	cellular_component	Golgi apparatus
z	0005829	cellular_component	cytosol
z	0005886	cellular_component	plasma membrane
z	0006260	biological_process	DNA replication
z	0006397	biological_process	mRNA processing
z	0008380	biological_process	RNA splicing
z	0016485	biological_process	protein processing
z	0016567	biological_process	protein ubiquitination
z	0016607	cellular_component	nuclear speck
z	0030515	molecular_function	snoRNA binding
z	0031571	biological_process	mitotic G1 DNA damage checkpoint signaling
z	0034644	biological_process	cellular response to UV
z	0042254	biological_process	ribosome biogenesis
z	0045292	biological_process	mRNA cis splicing, via spliceosome
z	0051301	biological_process	cell division
Z	0000122	biological_process	negative regulation of transcription by RNA polymerase II
Z	0003682	molecular_function	chromatin binding
Z	0003723	molecular_function	RNA binding
Z	0003729	molecular_function	mRNA binding
Z	0005515	molecular_function	protein binding
Z	0005634	cellular_component	nucleus
Z	0005654	cellular_component	nucleoplasm
Z	0005829	cellular_component	cytosol
Z	0007219	biological_process	Notch signaling pathway
Z	0030097	biological_process	hemopoiesis
Z	0030851	biological_process	granulocyte differentiation
Z	0031490	molecular_function	chromatin DNA binding
Z	0033077	biological_process	T cell differentiation in thymus
Z	0035019	biological_process	somatic stem cell population maintenance
Z	0045892	biological_process	negative regulation of DNA-templated transcription
Z	0046638	biological_process	positive regulation of alpha-beta T cell differentiation
Z	0060090	molecular_function	molecular adaptor activity
Z	0071425	biological_process	hematopoietic stem cell proliferation

Functional Information from PROSITE/UniProt

site_id	PS00039
Number of Residues	9
Details	DEAD_ATP_HELICASE DEAD-box subfamily ATP-dependent helicases signature. VLDEADEmL

Chain	Residue	Details
7	VAL185-LEU193

---

site_id	PS00170
Number of Residues	18
Details	CSA_PPIASE_1 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. FkgSsFHRIIpqFMcQGG

Chain	Residue	Details
CE	PHE184-GLY201
i	TYR48-GLY65
C3	TYR37-GLY54

---

site_id	PS00211
Number of Residues	15
Details	ABC_TRANSPORTER_1 ABC transporters family signature. VSKGQRVKVKVLSFT

Chain	Residue	Details
V	VAL313-THR327

---

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. LATAadDsSVKLWDL

Chain	Residue	Details
t	LEU407-LEU421
J	LEU303-VAL317
J	ILE345-LEU359
N	LEU81-VAL95
N	LEU124-SER138
N	VAL167-ILE181
N	ILE208-LEU222
N	ILE300-THR314
o	LEU304-VAL318

---

site_id	PS00690
Number of Residues	10
Details	DEAH_ATP_HELICASE DEAH-box subfamily ATP-dependent helicases signature. AiIMLDEAHE

Chain	Residue	Details
V	ALA680-GLU689

---

site_id	PS00997
Number of Residues	23
Details	G10_1 G10 protein signature 1. LCClRCiqtrDtNfgtnCiCRVP

Chain	Residue	Details
L	LEU100-PRO122

---

site_id	PS00998
Number of Residues	10
Details	G10_2 G10 protein signature 2. CtHCGCRGCS

Chain	Residue	Details
L	CYS134-SER143

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: N-acetylalanine => ECO:0000269|Ref.4, ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:22223895

Chain	Residue	Details
A	ALA2
u	SER2
v	SER2
w	SER2
7	ARG367
i	LYS125

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231

Chain	Residue	Details
A	SER859
t	LYS261
u	LYS122
u	LYS261
v	LYS122
v	LYS261
w	LYS122
w	LYS261

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
A	SER1358
t	LYS244
u	LYS179
u	LYS244
v	LYS179
v	LYS244
w	LYS179
w	LYS244

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: N6,N6-dimethyllysine => ECO:0007744|PubMed:24129315

Chain	Residue	Details
A	LYS1425
W	SER255
a	LYS8
m	LYS6
m	LYS8

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861

Chain	Residue	Details
A	LYS1463
R	SER1460
R	SER1462
R	SER1482
R	SER1483
R	SER1501
R	SER1621
R	SER1893
R	SER2343
R	SER2394
R	SER2453
R	SER222
Z	LYS305
R	SER484
R	SER486
R	SER875
R	SER1336
R	SER1368
R	SER1421

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P60842

Chain	Residue	Details
7	LYS124
K	LYS416
K	LYS441
K	LYS452
W	LYS221
h	LYS408
K	LYS141
K	LYS158
K	LYS258
K	LYS286
K	LYS339
K	LYS344

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
7	THR163
R	SER994
R	SER1014

---

site_id	SWS_FT_FI8
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P60843

Chain	Residue	Details
7	LYS198
R	SER1179
R	SER2581

---

site_id	SWS_FT_FI9
Number of Residues	2
Details	MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861

Chain	Residue	Details
7	LYS296
7	LYS321
R	SER1152

---

site_id	SWS_FT_FI10
Number of Residues	1
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:25218447, ECO:0007744|PubMed:25755297, ECO:0007744|PubMed:25772364, ECO:0007744|PubMed:28112733

Chain	Residue	Details
7	LYS19
R	SER857
R	SER952
R	SER1318
R	SER1401
R	SER2100

---

site_id	SWS_FT_FI11
Number of Residues	3
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733

Chain	Residue	Details
R	SER323
7	LYS314
7	LYS382

---

site_id	SWS_FT_FI12
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0000250|UniProtKB:P60842

Chain	Residue	Details
7	LYS152
7	LYS374

---

site_id	SWS_FT_FI13
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:19690332

Chain	Residue	Details
R	SER357
R	SER358
R	SER846
R	SER1214

---

site_id	SWS_FT_FI14
Number of Residues	3
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:19690332

Chain	Residue	Details
R	THR359
R	THR1106
R	THR2381

---

site_id	SWS_FT_FI15
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
R	THR367
O	LYS487

---

site_id	SWS_FT_FI16
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:17525332, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
R	SER377

---

site_id	SWS_FT_FI17
Number of Residues	2
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:24275569

Chain	Residue	Details
R	THR383
R	THR384

---

site_id	SWS_FT_FI18
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
R	SER387

---

site_id	SWS_FT_FI19
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:24275569

Chain	Residue	Details
R	SER395
R	SER935
R	SER1311

---

site_id	SWS_FT_FI20
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:24275569

Chain	Residue	Details
R	SER398

---

site_id	SWS_FT_FI21
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:24275569

Chain	Residue	Details
R	SER404
R	SER408

---

site_id	SWS_FT_FI22
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
R	SER424
R	SER1124
R	SER2702

---

site_id	SWS_FT_FI23
Number of Residues	12
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:23186163

Chain	Residue	Details
R	SER435
R	SER2121
R	SER2675
R	SER2677
R	SER780
R	SER864
R	SER1064
R	SER1112
R	SER1537
R	SER1539
R	SER1541
R	SER1876

---

site_id	SWS_FT_FI24
Number of Residues	24
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
R	SER436
R	SER704
R	SER706
R	SER992
R	SER1198
R	SER1227
R	SER1254
R	SER1257
R	SER1258
R	SER2018
R	SER2030
R	SER437
R	SER2042
R	SER2310
R	SER2368
R	SER2376
R	SER2740
R	SER506
R	SER508
R	SER510
R	SER534
R	SER536
R	SER543
R	SER702

---

site_id	SWS_FT_FI25
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
R	SER440
R	SER1188

---

site_id	SWS_FT_FI26
Number of Residues	5
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
R	SER778
R	SER2123
R	SER2398
R	SER2407
R	SER2692

---

site_id	SWS_FT_FI27
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:21406692

Chain	Residue	Details
R	SER783
R	SER1522
R	SER1970

---

site_id	SWS_FT_FI28
Number of Residues	12
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q8BTI8

Chain	Residue	Details
R	SER854
R	SER1423
R	SER1616
R	SER1620
R	SER1024
R	SER1042
R	SER1266
R	SER1270
R	SER1271
R	SER1348
R	SER1383
R	SER1384

---

site_id	SWS_FT_FI29
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:Q8BTI8

Chain	Residue	Details
R	THR856

---

site_id	SWS_FT_FI30
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
R	THR866

---

site_id	SWS_FT_FI31
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:20068231

Chain	Residue	Details
R	SER871

---

site_id	SWS_FT_FI32
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
R	SER876

---

site_id	SWS_FT_FI33
Number of Residues	24
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:21406692

Chain	Residue	Details
R	SER908
R	SER1582
R	SER1598
R	SER1600
R	SER1601
R	SER1658
R	SER1727
R	SER1729
R	SER1731
R	SER1732
R	SER1818
R	SER1129
R	SER1822
R	SER1884
R	SER2090
R	SER2415
R	SER2429
R	SER1424
R	SER1517
R	SER1519
R	SER1521
R	SER1577
R	SER1579
R	SER1581

---

site_id	SWS_FT_FI34
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
R	SER950

---

site_id	SWS_FT_FI35
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:23186163

Chain	Residue	Details
R	SER954

---

site_id	SWS_FT_FI36
Number of Residues	12
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648

Chain	Residue	Details
R	SER957
R	SER1946
R	SER1958
R	SER2118
R	SER968
R	SER970
R	SER972
R	SER1032
R	SER1451
R	SER1691
R	SER1693
R	SER1923

---

site_id	SWS_FT_FI37
Number of Residues	18
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692

Chain	Residue	Details
R	SER973
R	SER1975
R	SER1984
R	SER1987
R	SER1996
R	SER1999
R	SER2008
R	SER2011
R	SER2664
R	SER2706
R	SER1497
R	SER1502
R	SER1762
R	SER1764
R	SER1890
R	SER1916
R	SER1919
R	SER1972

---

site_id	SWS_FT_FI38
Number of Residues	5
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692

Chain	Residue	Details
R	SER974
R	SER1415
R	SER1925
R	SER1948
R	SER1960

---

site_id	SWS_FT_FI39
Number of Residues	7
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:21406692

Chain	Residue	Details
R	THR977
R	THR1043
R	THR1931
R	THR1954
R	THR1966
R	THR1978
R	THR2092

---

site_id	SWS_FT_FI40
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
R	THR983

---

site_id	SWS_FT_FI41
Number of Residues	2
Details	MOD_RES: Phosphotyrosine => ECO:0007744|PubMed:24275569

Chain	Residue	Details
R	TYR996
R	TYR1049

---

site_id	SWS_FT_FI42
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
R	THR1003

---

site_id	SWS_FT_FI43
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
R	SER1010

---

site_id	SWS_FT_FI44
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231

Chain	Residue	Details
R	SER1028
R	SER2690

---

site_id	SWS_FT_FI45
Number of Residues	7
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
R	SER1069
R	SER1444
R	SER1542
R	SER1552
R	SER1694
R	SER1878
R	SER2412

---

site_id	SWS_FT_FI46
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:18669648

Chain	Residue	Details
R	SER1072
R	SER1073

---

site_id	SWS_FT_FI47
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692

Chain	Residue	Details
R	SER1099
R	SER1101

---

site_id	SWS_FT_FI48
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332

Chain	Residue	Details
R	SER1102

---

site_id	SWS_FT_FI49
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
R	SER1103
R	SER1404
R	SER2132

---

site_id	SWS_FT_FI50
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
R	SER1122
R	SER1857
R	SER2335

---

site_id	SWS_FT_FI51
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
R	SER1132

---

site_id	SWS_FT_FI52
Number of Residues	2
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:23186163

Chain	Residue	Details
R	THR1208
R	THR1880

---

site_id	SWS_FT_FI53
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:24275569

Chain	Residue	Details
R	SER1219

---

site_id	SWS_FT_FI54
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
R	SER1320
R	SER1387

---

site_id	SWS_FT_FI55
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
R	SER1326

---

site_id	SWS_FT_FI56
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
R	SER1329

---

site_id	SWS_FT_FI57
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
R	SER1382

---

site_id	SWS_FT_FI58
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:23186163

Chain	Residue	Details
R	SER1403

---

site_id	SWS_FT_FI59
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
R	THR1413

---

site_id	SWS_FT_FI60
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
R	THR1434

---

site_id	SWS_FT_FI61
Number of Residues	5
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648

Chain	Residue	Details
R	THR1453
R	THR1472
R	THR1511
R	THR1698
R	THR2144

---

site_id	SWS_FT_FI62
Number of Residues	5
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
R	SER1458
R	SER1648
R	SER2020
R	SER2032
R	SER2067

---

site_id	SWS_FT_FI63
Number of Residues	9
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
R	SER1463
R	SER1499
R	SER1854
R	SER2044
R	SER2046
R	SER2071
R	SER2426
R	SER2684
R	SER2688

---

site_id	SWS_FT_FI64
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
R	THR1492

---

site_id	SWS_FT_FI65
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:17924679, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:23186163

Chain	Residue	Details
R	THR1531

---

site_id	SWS_FT_FI66
Number of Residues	3
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692

Chain	Residue	Details
R	THR1927
R	THR1950
R	THR1962

---

site_id	SWS_FT_FI67
Number of Residues	2
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
R	THR2022
R	THR2034

---

site_id	SWS_FT_FI68
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
R	THR2069

---

site_id	SWS_FT_FI69
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
R	SER2102

---

site_id	SWS_FT_FI70
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
R	THR2104

---

site_id	SWS_FT_FI71
Number of Residues	7
Details	MOD_RES: Omega-N-methylarginine => ECO:0007744|PubMed:24129315

Chain	Residue	Details
R	ARG2194
R	ARG2207
R	ARG2231
R	ARG2246
R	ARG2274
R	ARG2288
R	ARG2342

---

site_id	SWS_FT_FI72
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:18220336, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
R	SER2272

---

site_id	SWS_FT_FI73
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
R	THR2289

---

site_id	SWS_FT_FI74
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:16964243

Chain	Residue	Details
R	THR2291

---

site_id	SWS_FT_FI75
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231

Chain	Residue	Details
R	THR2302

---

site_id	SWS_FT_FI76
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:23186163

Chain	Residue	Details
R	THR2316

---

site_id	SWS_FT_FI77
Number of Residues	2
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
R	THR2329
R	THR2409

---

site_id	SWS_FT_FI78
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:24275569

Chain	Residue	Details
R	SER2382

---

site_id	SWS_FT_FI79
Number of Residues	1
Details	MOD_RES: Omega-N-methylarginine; alternate => ECO:0007744|PubMed:24129315

Chain	Residue	Details
R	ARG2384

---

site_id	SWS_FT_FI80
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:17525332, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
R	SER2449

---

site_id	SWS_FT_FI81
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:24275569

Chain	Residue	Details
R	THR2583

---

site_id	SWS_FT_FI82
Number of Residues	2
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
R	THR2599
R	THR2738

---

site_id	SWS_FT_FI83
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
R	SER2694

---

site_id	SWS_FT_FI84
Number of Residues	4
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733

Chain	Residue	Details
R	LYS108
R	LYS130
R	LYS2587

---