8C5G
Structure of human Neuropilin-1 b1b2 domains in complex with Chlorotoxin (Leiurus quinquestriatus)
This is a non-PDB format compatible entry.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| C | 0004857 | molecular_function | enzyme inhibitor activity |
| C | 0005576 | cellular_component | extracellular region |
| C | 0017081 | molecular_function | chloride channel regulator activity |
| C | 0030414 | molecular_function | peptidase inhibitor activity |
| C | 0035821 | biological_process | modulation of process of another organism |
| C | 0090729 | molecular_function | toxin activity |
| C | 0099106 | molecular_function | ion channel regulator activity |
| D | 0004857 | molecular_function | enzyme inhibitor activity |
| D | 0005576 | cellular_component | extracellular region |
| D | 0017081 | molecular_function | chloride channel regulator activity |
| D | 0030414 | molecular_function | peptidase inhibitor activity |
| D | 0035821 | biological_process | modulation of process of another organism |
| D | 0090729 | molecular_function | toxin activity |
| D | 0099106 | molecular_function | ion channel regulator activity |
Functional Information from PROSITE/UniProt
| site_id | PS01285 |
| Number of Residues | 30 |
| Details | FA58C_1 Coagulation factors 5/8 type C domain (FA58C) signature 1. GWtpgedsyre......WIqVDlgllrfVtaVgTQG |
| Chain | Residue | Details |
| A | GLY314-GLY343 | |
| A | GLY470-GLY502 |
| site_id | PS01286 |
| Number of Residues | 17 |
| Details | FA58C_2 Coagulation factors 5/8 type C domain (FA58C) signature 2. Patwetgis..MRfEVyGC |
| Chain | Residue | Details |
| A | PRO408-CYS424 | |
| A | PRO566-CYS583 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 298 |
| Details | Domain: {"description":"F5/8 type C 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00081","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 70 |
| Details | Peptide: {"description":"Chlorotoxin","featureId":"PRO_0000044941","evidences":[{"source":"PubMed","id":"8383429","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
