8BZR
UFC1-UFM1 conjugate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0007420 | biological_process | brain development |
| A | 0032649 | biological_process | regulation of type II interferon production |
| A | 0034976 | biological_process | response to endoplasmic reticulum stress |
| A | 0061657 | molecular_function | UFM1 conjugating enzyme activity |
| A | 0061709 | biological_process | reticulophagy |
| A | 0070062 | cellular_component | extracellular exosome |
| A | 0071568 | molecular_function | UFM1 transferase activity |
| A | 0071569 | biological_process | protein ufmylation |
| A | 1990592 | biological_process | protein K69-linked ufmylation |
| B | 0005515 | molecular_function | protein binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005783 | cellular_component | endoplasmic reticulum |
| B | 0007420 | biological_process | brain development |
| B | 0033146 | biological_process | regulation of intracellular estrogen receptor signaling pathway |
| B | 0034976 | biological_process | response to endoplasmic reticulum stress |
| B | 0042308 | biological_process | negative regulation of protein import into nucleus |
| B | 0043066 | biological_process | negative regulation of apoptotic process |
| B | 0061709 | biological_process | reticulophagy |
| B | 0071569 | biological_process | protein ufmylation |
| B | 1990592 | biological_process | protein K69-linked ufmylation |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Glycyl thioester intermediate","evidences":[{"source":"PubMed","id":"15071506","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29868776","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34588452","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in UFM1)","evidences":[{"source":"PubMed","id":"35926457","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in UFM1)","evidences":[{"source":"PubMed","id":"25219498","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)","evidences":[{"source":"PubMed","id":"15071506","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25219498","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27653677","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
