8BMT

Structure of GroEL:GroES-ATP complex plunge frozen 200 ms after reaction initiation

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0000287	molecular_function	magnesium ion binding
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006457	biological_process	protein folding
A	0009314	biological_process	response to radiation
A	0009408	biological_process	response to heat
A	0016020	cellular_component	membrane
A	0016853	molecular_function	isomerase activity
A	0016887	molecular_function	ATP hydrolysis activity
A	0019068	biological_process	virion assembly
A	0042026	biological_process	protein refolding
A	0042802	molecular_function	identical protein binding
A	0051082	molecular_function	unfolded protein binding
A	0140662	molecular_function	ATP-dependent protein folding chaperone
A	1990220	cellular_component	GroEL-GroES complex
AA	0005515	molecular_function	protein binding
AA	0005524	molecular_function	ATP binding
AA	0005737	cellular_component	cytoplasm
AA	0005829	cellular_component	cytosol
AA	0006457	biological_process	protein folding
AA	0009408	biological_process	response to heat
AA	0019068	biological_process	virion assembly
AA	0042802	molecular_function	identical protein binding
AA	0044183	molecular_function	protein folding chaperone
AA	0046872	molecular_function	metal ion binding
AA	0051082	molecular_function	unfolded protein binding
AA	0051087	molecular_function	protein-folding chaperone binding
AA	1990220	cellular_component	GroEL-GroES complex
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006457	biological_process	protein folding
B	0009408	biological_process	response to heat
B	0019068	biological_process	virion assembly
B	0042802	molecular_function	identical protein binding
B	0044183	molecular_function	protein folding chaperone
B	0046872	molecular_function	metal ion binding
B	0051082	molecular_function	unfolded protein binding
B	0051087	molecular_function	protein-folding chaperone binding
B	1990220	cellular_component	GroEL-GroES complex
BA	0000166	molecular_function	nucleotide binding
BA	0000287	molecular_function	magnesium ion binding
BA	0005515	molecular_function	protein binding
BA	0005524	molecular_function	ATP binding
BA	0005737	cellular_component	cytoplasm
BA	0005829	cellular_component	cytosol
BA	0006457	biological_process	protein folding
BA	0009314	biological_process	response to radiation
BA	0009408	biological_process	response to heat
BA	0016020	cellular_component	membrane
BA	0016853	molecular_function	isomerase activity
BA	0016887	molecular_function	ATP hydrolysis activity
BA	0019068	biological_process	virion assembly
BA	0042026	biological_process	protein refolding
BA	0042802	molecular_function	identical protein binding
BA	0051082	molecular_function	unfolded protein binding
BA	0140662	molecular_function	ATP-dependent protein folding chaperone
BA	1990220	cellular_component	GroEL-GroES complex
C	0000166	molecular_function	nucleotide binding
C	0000287	molecular_function	magnesium ion binding
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006457	biological_process	protein folding
C	0009314	biological_process	response to radiation
C	0009408	biological_process	response to heat
C	0016020	cellular_component	membrane
C	0016853	molecular_function	isomerase activity
C	0016887	molecular_function	ATP hydrolysis activity
C	0019068	biological_process	virion assembly
C	0042026	biological_process	protein refolding
C	0042802	molecular_function	identical protein binding
C	0051082	molecular_function	unfolded protein binding
C	0140662	molecular_function	ATP-dependent protein folding chaperone
C	1990220	cellular_component	GroEL-GroES complex
CA	0005515	molecular_function	protein binding
CA	0005524	molecular_function	ATP binding
CA	0005737	cellular_component	cytoplasm
CA	0005829	cellular_component	cytosol
CA	0006457	biological_process	protein folding
CA	0009408	biological_process	response to heat
CA	0019068	biological_process	virion assembly
CA	0042802	molecular_function	identical protein binding
CA	0044183	molecular_function	protein folding chaperone
CA	0046872	molecular_function	metal ion binding
CA	0051082	molecular_function	unfolded protein binding
CA	0051087	molecular_function	protein-folding chaperone binding
CA	1990220	cellular_component	GroEL-GroES complex
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006457	biological_process	protein folding
D	0009408	biological_process	response to heat
D	0019068	biological_process	virion assembly
D	0042802	molecular_function	identical protein binding
D	0044183	molecular_function	protein folding chaperone
D	0046872	molecular_function	metal ion binding
D	0051082	molecular_function	unfolded protein binding
D	0051087	molecular_function	protein-folding chaperone binding
D	1990220	cellular_component	GroEL-GroES complex
E	0000166	molecular_function	nucleotide binding
E	0000287	molecular_function	magnesium ion binding
E	0005515	molecular_function	protein binding
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0006457	biological_process	protein folding
E	0009314	biological_process	response to radiation
E	0009408	biological_process	response to heat
E	0016020	cellular_component	membrane
E	0016853	molecular_function	isomerase activity
E	0016887	molecular_function	ATP hydrolysis activity
E	0019068	biological_process	virion assembly
E	0042026	biological_process	protein refolding
E	0042802	molecular_function	identical protein binding
E	0051082	molecular_function	unfolded protein binding
E	0140662	molecular_function	ATP-dependent protein folding chaperone
E	1990220	cellular_component	GroEL-GroES complex
F	0005515	molecular_function	protein binding
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0006457	biological_process	protein folding
F	0009408	biological_process	response to heat
F	0019068	biological_process	virion assembly
F	0042802	molecular_function	identical protein binding
F	0044183	molecular_function	protein folding chaperone
F	0046872	molecular_function	metal ion binding
F	0051082	molecular_function	unfolded protein binding
F	0051087	molecular_function	protein-folding chaperone binding
F	1990220	cellular_component	GroEL-GroES complex
G	0000166	molecular_function	nucleotide binding
G	0000287	molecular_function	magnesium ion binding
G	0005515	molecular_function	protein binding
G	0005524	molecular_function	ATP binding
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0006457	biological_process	protein folding
G	0009314	biological_process	response to radiation
G	0009408	biological_process	response to heat
G	0016020	cellular_component	membrane
G	0016853	molecular_function	isomerase activity
G	0016887	molecular_function	ATP hydrolysis activity
G	0019068	biological_process	virion assembly
G	0042026	biological_process	protein refolding
G	0042802	molecular_function	identical protein binding
G	0051082	molecular_function	unfolded protein binding
G	0140662	molecular_function	ATP-dependent protein folding chaperone
G	1990220	cellular_component	GroEL-GroES complex
H	0005515	molecular_function	protein binding
H	0005524	molecular_function	ATP binding
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0006457	biological_process	protein folding
H	0009408	biological_process	response to heat
H	0019068	biological_process	virion assembly
H	0042802	molecular_function	identical protein binding
H	0044183	molecular_function	protein folding chaperone
H	0046872	molecular_function	metal ion binding
H	0051082	molecular_function	unfolded protein binding
H	0051087	molecular_function	protein-folding chaperone binding
H	1990220	cellular_component	GroEL-GroES complex
I	0000166	molecular_function	nucleotide binding
I	0000287	molecular_function	magnesium ion binding
I	0005515	molecular_function	protein binding
I	0005524	molecular_function	ATP binding
I	0005737	cellular_component	cytoplasm
I	0005829	cellular_component	cytosol
I	0006457	biological_process	protein folding
I	0009314	biological_process	response to radiation
I	0009408	biological_process	response to heat
I	0016020	cellular_component	membrane
I	0016853	molecular_function	isomerase activity
I	0016887	molecular_function	ATP hydrolysis activity
I	0019068	biological_process	virion assembly
I	0042026	biological_process	protein refolding
I	0042802	molecular_function	identical protein binding
I	0051082	molecular_function	unfolded protein binding
I	0140662	molecular_function	ATP-dependent protein folding chaperone
I	1990220	cellular_component	GroEL-GroES complex
J	0000166	molecular_function	nucleotide binding
J	0000287	molecular_function	magnesium ion binding
J	0005515	molecular_function	protein binding
J	0005524	molecular_function	ATP binding
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0006457	biological_process	protein folding
J	0009314	biological_process	response to radiation
J	0009408	biological_process	response to heat
J	0016020	cellular_component	membrane
J	0016853	molecular_function	isomerase activity
J	0016887	molecular_function	ATP hydrolysis activity
J	0019068	biological_process	virion assembly
J	0042026	biological_process	protein refolding
J	0042802	molecular_function	identical protein binding
J	0051082	molecular_function	unfolded protein binding
J	0140662	molecular_function	ATP-dependent protein folding chaperone
J	1990220	cellular_component	GroEL-GroES complex
K	0005515	molecular_function	protein binding
K	0005524	molecular_function	ATP binding
K	0005737	cellular_component	cytoplasm
K	0005829	cellular_component	cytosol
K	0006457	biological_process	protein folding
K	0009408	biological_process	response to heat
K	0019068	biological_process	virion assembly
K	0042802	molecular_function	identical protein binding
K	0044183	molecular_function	protein folding chaperone
K	0046872	molecular_function	metal ion binding
K	0051082	molecular_function	unfolded protein binding
K	0051087	molecular_function	protein-folding chaperone binding
K	1990220	cellular_component	GroEL-GroES complex
L	0000166	molecular_function	nucleotide binding
L	0000287	molecular_function	magnesium ion binding
L	0005515	molecular_function	protein binding
L	0005524	molecular_function	ATP binding
L	0005737	cellular_component	cytoplasm
L	0005829	cellular_component	cytosol
L	0006457	biological_process	protein folding
L	0009314	biological_process	response to radiation
L	0009408	biological_process	response to heat
L	0016020	cellular_component	membrane
L	0016853	molecular_function	isomerase activity
L	0016887	molecular_function	ATP hydrolysis activity
L	0019068	biological_process	virion assembly
L	0042026	biological_process	protein refolding
L	0042802	molecular_function	identical protein binding
L	0051082	molecular_function	unfolded protein binding
L	0140662	molecular_function	ATP-dependent protein folding chaperone
L	1990220	cellular_component	GroEL-GroES complex
M	0005515	molecular_function	protein binding
M	0005524	molecular_function	ATP binding
M	0005737	cellular_component	cytoplasm
M	0005829	cellular_component	cytosol
M	0006457	biological_process	protein folding
M	0009408	biological_process	response to heat
M	0019068	biological_process	virion assembly
M	0042802	molecular_function	identical protein binding
M	0044183	molecular_function	protein folding chaperone
M	0046872	molecular_function	metal ion binding
M	0051082	molecular_function	unfolded protein binding
M	0051087	molecular_function	protein-folding chaperone binding
M	1990220	cellular_component	GroEL-GroES complex
N	0000166	molecular_function	nucleotide binding
N	0000287	molecular_function	magnesium ion binding
N	0005515	molecular_function	protein binding
N	0005524	molecular_function	ATP binding
N	0005737	cellular_component	cytoplasm
N	0005829	cellular_component	cytosol
N	0006457	biological_process	protein folding
N	0009314	biological_process	response to radiation
N	0009408	biological_process	response to heat
N	0016020	cellular_component	membrane
N	0016853	molecular_function	isomerase activity
N	0016887	molecular_function	ATP hydrolysis activity
N	0019068	biological_process	virion assembly
N	0042026	biological_process	protein refolding
N	0042802	molecular_function	identical protein binding
N	0051082	molecular_function	unfolded protein binding
N	0140662	molecular_function	ATP-dependent protein folding chaperone
N	1990220	cellular_component	GroEL-GroES complex
O	0005515	molecular_function	protein binding
O	0005524	molecular_function	ATP binding
O	0005737	cellular_component	cytoplasm
O	0005829	cellular_component	cytosol
O	0006457	biological_process	protein folding
O	0009408	biological_process	response to heat
O	0019068	biological_process	virion assembly
O	0042802	molecular_function	identical protein binding
O	0044183	molecular_function	protein folding chaperone
O	0046872	molecular_function	metal ion binding
O	0051082	molecular_function	unfolded protein binding
O	0051087	molecular_function	protein-folding chaperone binding
O	1990220	cellular_component	GroEL-GroES complex
P	0000166	molecular_function	nucleotide binding
P	0000287	molecular_function	magnesium ion binding
P	0005515	molecular_function	protein binding
P	0005524	molecular_function	ATP binding
P	0005737	cellular_component	cytoplasm
P	0005829	cellular_component	cytosol
P	0006457	biological_process	protein folding
P	0009314	biological_process	response to radiation
P	0009408	biological_process	response to heat
P	0016020	cellular_component	membrane
P	0016853	molecular_function	isomerase activity
P	0016887	molecular_function	ATP hydrolysis activity
P	0019068	biological_process	virion assembly
P	0042026	biological_process	protein refolding
P	0042802	molecular_function	identical protein binding
P	0051082	molecular_function	unfolded protein binding
P	0140662	molecular_function	ATP-dependent protein folding chaperone
P	1990220	cellular_component	GroEL-GroES complex
Q	0005515	molecular_function	protein binding
Q	0005524	molecular_function	ATP binding
Q	0005737	cellular_component	cytoplasm
Q	0005829	cellular_component	cytosol
Q	0006457	biological_process	protein folding
Q	0009408	biological_process	response to heat
Q	0019068	biological_process	virion assembly
Q	0042802	molecular_function	identical protein binding
Q	0044183	molecular_function	protein folding chaperone
Q	0046872	molecular_function	metal ion binding
Q	0051082	molecular_function	unfolded protein binding
Q	0051087	molecular_function	protein-folding chaperone binding
Q	1990220	cellular_component	GroEL-GroES complex
R	0000166	molecular_function	nucleotide binding
R	0000287	molecular_function	magnesium ion binding
R	0005515	molecular_function	protein binding
R	0005524	molecular_function	ATP binding
R	0005737	cellular_component	cytoplasm
R	0005829	cellular_component	cytosol
R	0006457	biological_process	protein folding
R	0009314	biological_process	response to radiation
R	0009408	biological_process	response to heat
R	0016020	cellular_component	membrane
R	0016853	molecular_function	isomerase activity
R	0016887	molecular_function	ATP hydrolysis activity
R	0019068	biological_process	virion assembly
R	0042026	biological_process	protein refolding
R	0042802	molecular_function	identical protein binding
R	0051082	molecular_function	unfolded protein binding
R	0140662	molecular_function	ATP-dependent protein folding chaperone
R	1990220	cellular_component	GroEL-GroES complex
S	0005515	molecular_function	protein binding
S	0005524	molecular_function	ATP binding
S	0005737	cellular_component	cytoplasm
S	0005829	cellular_component	cytosol
S	0006457	biological_process	protein folding
S	0009408	biological_process	response to heat
S	0019068	biological_process	virion assembly
S	0042802	molecular_function	identical protein binding
S	0044183	molecular_function	protein folding chaperone
S	0046872	molecular_function	metal ion binding
S	0051082	molecular_function	unfolded protein binding
S	0051087	molecular_function	protein-folding chaperone binding
S	1990220	cellular_component	GroEL-GroES complex
T	0000166	molecular_function	nucleotide binding
T	0000287	molecular_function	magnesium ion binding
T	0005515	molecular_function	protein binding
T	0005524	molecular_function	ATP binding
T	0005737	cellular_component	cytoplasm
T	0005829	cellular_component	cytosol
T	0006457	biological_process	protein folding
T	0009314	biological_process	response to radiation
T	0009408	biological_process	response to heat
T	0016020	cellular_component	membrane
T	0016853	molecular_function	isomerase activity
T	0016887	molecular_function	ATP hydrolysis activity
T	0019068	biological_process	virion assembly
T	0042026	biological_process	protein refolding
T	0042802	molecular_function	identical protein binding
T	0051082	molecular_function	unfolded protein binding
T	0140662	molecular_function	ATP-dependent protein folding chaperone
T	1990220	cellular_component	GroEL-GroES complex
V	0005515	molecular_function	protein binding
V	0005524	molecular_function	ATP binding
V	0005737	cellular_component	cytoplasm
V	0005829	cellular_component	cytosol
V	0006457	biological_process	protein folding
V	0009408	biological_process	response to heat
V	0019068	biological_process	virion assembly
V	0042802	molecular_function	identical protein binding
V	0044183	molecular_function	protein folding chaperone
V	0046872	molecular_function	metal ion binding
V	0051082	molecular_function	unfolded protein binding
V	0051087	molecular_function	protein-folding chaperone binding
V	1990220	cellular_component	GroEL-GroES complex
W	0005515	molecular_function	protein binding
W	0005524	molecular_function	ATP binding
W	0005737	cellular_component	cytoplasm
W	0005829	cellular_component	cytosol
W	0006457	biological_process	protein folding
W	0009408	biological_process	response to heat
W	0019068	biological_process	virion assembly
W	0042802	molecular_function	identical protein binding
W	0044183	molecular_function	protein folding chaperone
W	0046872	molecular_function	metal ion binding
W	0051082	molecular_function	unfolded protein binding
W	0051087	molecular_function	protein-folding chaperone binding
W	1990220	cellular_component	GroEL-GroES complex
X	0000166	molecular_function	nucleotide binding
X	0000287	molecular_function	magnesium ion binding
X	0005515	molecular_function	protein binding
X	0005524	molecular_function	ATP binding
X	0005737	cellular_component	cytoplasm
X	0005829	cellular_component	cytosol
X	0006457	biological_process	protein folding
X	0009314	biological_process	response to radiation
X	0009408	biological_process	response to heat
X	0016020	cellular_component	membrane
X	0016853	molecular_function	isomerase activity
X	0016887	molecular_function	ATP hydrolysis activity
X	0019068	biological_process	virion assembly
X	0042026	biological_process	protein refolding
X	0042802	molecular_function	identical protein binding
X	0051082	molecular_function	unfolded protein binding
X	0140662	molecular_function	ATP-dependent protein folding chaperone
X	1990220	cellular_component	GroEL-GroES complex
Y	0005515	molecular_function	protein binding
Y	0005524	molecular_function	ATP binding
Y	0005737	cellular_component	cytoplasm
Y	0005829	cellular_component	cytosol
Y	0006457	biological_process	protein folding
Y	0009408	biological_process	response to heat
Y	0019068	biological_process	virion assembly
Y	0042802	molecular_function	identical protein binding
Y	0044183	molecular_function	protein folding chaperone
Y	0046872	molecular_function	metal ion binding
Y	0051082	molecular_function	unfolded protein binding
Y	0051087	molecular_function	protein-folding chaperone binding
Y	1990220	cellular_component	GroEL-GroES complex
Z	0000166	molecular_function	nucleotide binding
Z	0000287	molecular_function	magnesium ion binding
Z	0005515	molecular_function	protein binding
Z	0005524	molecular_function	ATP binding
Z	0005737	cellular_component	cytoplasm
Z	0005829	cellular_component	cytosol
Z	0006457	biological_process	protein folding
Z	0009314	biological_process	response to radiation
Z	0009408	biological_process	response to heat
Z	0016020	cellular_component	membrane
Z	0016853	molecular_function	isomerase activity
Z	0016887	molecular_function	ATP hydrolysis activity
Z	0019068	biological_process	virion assembly
Z	0042026	biological_process	protein refolding
Z	0042802	molecular_function	identical protein binding
Z	0051082	molecular_function	unfolded protein binding
Z	0140662	molecular_function	ATP-dependent protein folding chaperone
Z	1990220	cellular_component	GroEL-GroES complex

Functional Information from PROSITE/UniProt

site_id	PS00296
Number of Residues	12
Details	CHAPERONINS_CPN60 Chaperonins cpn60 signature. AAVEEGVVaGGG

Chain	Residue	Details
I	ALA405-GLY416

---

site_id	PS00681
Number of Residues	25
Details	CHAPERONINS_CPN10 Chaperonins cpn10 signature. IrPLhDRVIVKrkevetksaGgIVL

Chain	Residue	Details
W	ILE3-LEU27

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	154
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00600","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"25174333","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14517228","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"9285585","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1AON","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1PCQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1PF9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3WVL","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	14
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00600","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"25174333","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14517228","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"9285585","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1AON","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1PF9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3WVL","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	84
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"PubMed","id":"21151122","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	14
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"PubMed","id":"21151122","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---