Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

8BM3

H207A mutant of E. coli PgpB, a PAP2 type phosphatidyl glycerol phosphate and C55-PP phosphatase, in complex with farnesyl pyrophosphate

Functional Information from GO Data
ChainGOidnamespacecontents
A0000810molecular_functiondiacylglycerol diphosphate phosphatase activity
A0005886cellular_componentplasma membrane
A0006655biological_processphosphatidylglycerol biosynthetic process
A0008195molecular_functionphosphatidate phosphatase activity
A0008962molecular_functionphosphatidylglycerophosphatase activity
A0009252biological_processpeptidoglycan biosynthetic process
A0009279cellular_componentcell outer membrane
A0009395biological_processphospholipid catabolic process
A0016787molecular_functionhydrolase activity
A0046474biological_processglycerophospholipid biosynthetic process
A0050380molecular_functionundecaprenyl-diphosphatase activity
B0000810molecular_functiondiacylglycerol diphosphate phosphatase activity
B0005886cellular_componentplasma membrane
B0006655biological_processphosphatidylglycerol biosynthetic process
B0008195molecular_functionphosphatidate phosphatase activity
B0008962molecular_functionphosphatidylglycerophosphatase activity
B0009252biological_processpeptidoglycan biosynthetic process
B0009279cellular_componentcell outer membrane
B0009395biological_processphospholipid catabolic process
B0016787molecular_functionhydrolase activity
B0046474biological_processglycerophospholipid biosynthetic process
B0050380molecular_functionundecaprenyl-diphosphatase activity
C0000810molecular_functiondiacylglycerol diphosphate phosphatase activity
C0005886cellular_componentplasma membrane
C0006655biological_processphosphatidylglycerol biosynthetic process
C0008195molecular_functionphosphatidate phosphatase activity
C0008962molecular_functionphosphatidylglycerophosphatase activity
C0009252biological_processpeptidoglycan biosynthetic process
C0009279cellular_componentcell outer membrane
C0009395biological_processphospholipid catabolic process
C0016787molecular_functionhydrolase activity
C0046474biological_processglycerophospholipid biosynthetic process
C0050380molecular_functionundecaprenyl-diphosphatase activity
D0000810molecular_functiondiacylglycerol diphosphate phosphatase activity
D0005886cellular_componentplasma membrane
D0006655biological_processphosphatidylglycerol biosynthetic process
D0008195molecular_functionphosphatidate phosphatase activity
D0008962molecular_functionphosphatidylglycerophosphatase activity
D0009252biological_processpeptidoglycan biosynthetic process
D0009279cellular_componentcell outer membrane
D0009395biological_processphospholipid catabolic process
D0016787molecular_functionhydrolase activity
D0046474biological_processglycerophospholipid biosynthetic process
D0050380molecular_functionundecaprenyl-diphosphatase activity
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues444
DetailsTRANSMEM: Helical => ECO:0000269|PubMed:24821770
ChainResidueDetails
AARG2-ILE24
BGLY162-GLY176
BARG183-LEU202
BPRO209-ARG232
CARG2-ILE24
CILE55-TRP66
CILE72-SER94
CGLY162-GLY176
CARG183-LEU202
CPRO209-ARG232
DARG2-ILE24
AILE55-TRP66
DILE55-TRP66
DILE72-SER94
DGLY162-GLY176
DARG183-LEU202
DPRO209-ARG232
AILE72-SER94
AGLY162-GLY176
AARG183-LEU202
APRO209-ARG232
BARG2-ILE24
BILE55-TRP66
BILE72-SER94

site_idSWS_FT_FI2
Number of Residues400
DetailsTOPO_DOM: Periplasmic => ECO:0000305|PubMed:24821770
ChainResidueDetails
ASER25-VAL54
DSER25-VAL54
DTRP95-SER161
DLEU203-TRP208
ATRP95-SER161
ALEU203-TRP208
BSER25-VAL54
BTRP95-SER161
BLEU203-TRP208
CSER25-VAL54
CTRP95-SER161
CLEU203-TRP208

site_idSWS_FT_FI3
Number of Residues120
DetailsTOPO_DOM: Cytoplasmic => ECO:0000305|PubMed:24821770
ChainResidueDetails
ACYS67-ARG71
DCYS67-ARG71
DLEU177-ARG182
DILE233-SER254
ALEU177-ARG182
AILE233-SER254
BCYS67-ARG71
BLEU177-ARG182
BILE233-SER254
CCYS67-ARG71
CLEU177-ARG182
CILE233-SER254

site_idSWS_FT_FI4
Number of Residues4
DetailsACT_SITE: Proton donor; for a subset of substrates => ECO:0000269|PubMed:27405756
ChainResidueDetails
AHIS163
BHIS163
CHIS163
DHIS163

site_idSWS_FT_FI5
Number of Residues4
DetailsACT_SITE: Nucleophile => ECO:0000269|PubMed:27405756
ChainResidueDetails
AALA207
BALA207
CALA207
DALA207

site_idSWS_FT_FI6
Number of Residues4
DetailsSITE: Stabilizes the active site histidine for nucleophilic attack => ECO:0000305|PubMed:27405756
ChainResidueDetails
AASP211
BASP211
CASP211
DASP211

221051

PDB entries from 2024-06-12

PDB statisticsPDBj update infoContact PDBjnumon