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8BM1

Structure of GroEL:GroES-ATP complex under continuous turnover conditions

Functional Information from GO Data
ChainGOidnamespacecontents
A0000287molecular_functionmagnesium ion binding
A0005515molecular_functionprotein binding
A0005524molecular_functionATP binding
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0006457biological_processprotein folding
A0009314biological_processresponse to radiation
A0009408biological_processresponse to heat
A0016020cellular_componentmembrane
A0016853molecular_functionisomerase activity
A0016887molecular_functionATP hydrolysis activity
A0019068biological_processvirion assembly
A0042026biological_processprotein refolding
A0042802molecular_functionidentical protein binding
A0051082molecular_functionunfolded protein binding
A0051085biological_processchaperone cofactor-dependent protein refolding
A0140662molecular_functionATP-dependent protein folding chaperone
A1990220cellular_componentGroEL-GroES complex
B0005515molecular_functionprotein binding
B0005524molecular_functionATP binding
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0006457biological_processprotein folding
B0009408biological_processresponse to heat
B0019068biological_processvirion assembly
B0042802molecular_functionidentical protein binding
B0044183molecular_functionprotein folding chaperone
B0046872molecular_functionmetal ion binding
B0051082molecular_functionunfolded protein binding
B0051085biological_processchaperone cofactor-dependent protein refolding
B0051087molecular_functionprotein-folding chaperone binding
B1990220cellular_componentGroEL-GroES complex
C0000287molecular_functionmagnesium ion binding
C0005515molecular_functionprotein binding
C0005524molecular_functionATP binding
C0005737cellular_componentcytoplasm
C0005829cellular_componentcytosol
C0006457biological_processprotein folding
C0009314biological_processresponse to radiation
C0009408biological_processresponse to heat
C0016020cellular_componentmembrane
C0016853molecular_functionisomerase activity
C0016887molecular_functionATP hydrolysis activity
C0019068biological_processvirion assembly
C0042026biological_processprotein refolding
C0042802molecular_functionidentical protein binding
C0051082molecular_functionunfolded protein binding
C0051085biological_processchaperone cofactor-dependent protein refolding
C0140662molecular_functionATP-dependent protein folding chaperone
C1990220cellular_componentGroEL-GroES complex
D0000287molecular_functionmagnesium ion binding
D0005515molecular_functionprotein binding
D0005524molecular_functionATP binding
D0005737cellular_componentcytoplasm
D0005829cellular_componentcytosol
D0006457biological_processprotein folding
D0009314biological_processresponse to radiation
D0009408biological_processresponse to heat
D0016020cellular_componentmembrane
D0016853molecular_functionisomerase activity
D0016887molecular_functionATP hydrolysis activity
D0019068biological_processvirion assembly
D0042026biological_processprotein refolding
D0042802molecular_functionidentical protein binding
D0051082molecular_functionunfolded protein binding
D0051085biological_processchaperone cofactor-dependent protein refolding
D0140662molecular_functionATP-dependent protein folding chaperone
D1990220cellular_componentGroEL-GroES complex
E0005515molecular_functionprotein binding
E0005524molecular_functionATP binding
E0005737cellular_componentcytoplasm
E0005829cellular_componentcytosol
E0006457biological_processprotein folding
E0009408biological_processresponse to heat
E0019068biological_processvirion assembly
E0042802molecular_functionidentical protein binding
E0044183molecular_functionprotein folding chaperone
E0046872molecular_functionmetal ion binding
E0051082molecular_functionunfolded protein binding
E0051085biological_processchaperone cofactor-dependent protein refolding
E0051087molecular_functionprotein-folding chaperone binding
E1990220cellular_componentGroEL-GroES complex
F0000287molecular_functionmagnesium ion binding
F0005515molecular_functionprotein binding
F0005524molecular_functionATP binding
F0005737cellular_componentcytoplasm
F0005829cellular_componentcytosol
F0006457biological_processprotein folding
F0009314biological_processresponse to radiation
F0009408biological_processresponse to heat
F0016020cellular_componentmembrane
F0016853molecular_functionisomerase activity
F0016887molecular_functionATP hydrolysis activity
F0019068biological_processvirion assembly
F0042026biological_processprotein refolding
F0042802molecular_functionidentical protein binding
F0051082molecular_functionunfolded protein binding
F0051085biological_processchaperone cofactor-dependent protein refolding
F0140662molecular_functionATP-dependent protein folding chaperone
F1990220cellular_componentGroEL-GroES complex
G0000287molecular_functionmagnesium ion binding
G0005515molecular_functionprotein binding
G0005524molecular_functionATP binding
G0005737cellular_componentcytoplasm
G0005829cellular_componentcytosol
G0006457biological_processprotein folding
G0009314biological_processresponse to radiation
G0009408biological_processresponse to heat
G0016020cellular_componentmembrane
G0016853molecular_functionisomerase activity
G0016887molecular_functionATP hydrolysis activity
G0019068biological_processvirion assembly
G0042026biological_processprotein refolding
G0042802molecular_functionidentical protein binding
G0051082molecular_functionunfolded protein binding
G0051085biological_processchaperone cofactor-dependent protein refolding
G0140662molecular_functionATP-dependent protein folding chaperone
G1990220cellular_componentGroEL-GroES complex
H0000287molecular_functionmagnesium ion binding
H0005515molecular_functionprotein binding
H0005524molecular_functionATP binding
H0005737cellular_componentcytoplasm
H0005829cellular_componentcytosol
H0006457biological_processprotein folding
H0009314biological_processresponse to radiation
H0009408biological_processresponse to heat
H0016020cellular_componentmembrane
H0016853molecular_functionisomerase activity
H0016887molecular_functionATP hydrolysis activity
H0019068biological_processvirion assembly
H0042026biological_processprotein refolding
H0042802molecular_functionidentical protein binding
H0051082molecular_functionunfolded protein binding
H0051085biological_processchaperone cofactor-dependent protein refolding
H0140662molecular_functionATP-dependent protein folding chaperone
H1990220cellular_componentGroEL-GroES complex
I0000287molecular_functionmagnesium ion binding
I0005515molecular_functionprotein binding
I0005524molecular_functionATP binding
I0005737cellular_componentcytoplasm
I0005829cellular_componentcytosol
I0006457biological_processprotein folding
I0009314biological_processresponse to radiation
I0009408biological_processresponse to heat
I0016020cellular_componentmembrane
I0016853molecular_functionisomerase activity
I0016887molecular_functionATP hydrolysis activity
I0019068biological_processvirion assembly
I0042026biological_processprotein refolding
I0042802molecular_functionidentical protein binding
I0051082molecular_functionunfolded protein binding
I0051085biological_processchaperone cofactor-dependent protein refolding
I0140662molecular_functionATP-dependent protein folding chaperone
I1990220cellular_componentGroEL-GroES complex
J0005515molecular_functionprotein binding
J0005524molecular_functionATP binding
J0005737cellular_componentcytoplasm
J0005829cellular_componentcytosol
J0006457biological_processprotein folding
J0009408biological_processresponse to heat
J0019068biological_processvirion assembly
J0042802molecular_functionidentical protein binding
J0044183molecular_functionprotein folding chaperone
J0046872molecular_functionmetal ion binding
J0051082molecular_functionunfolded protein binding
J0051085biological_processchaperone cofactor-dependent protein refolding
J0051087molecular_functionprotein-folding chaperone binding
J1990220cellular_componentGroEL-GroES complex
K0000287molecular_functionmagnesium ion binding
K0005515molecular_functionprotein binding
K0005524molecular_functionATP binding
K0005737cellular_componentcytoplasm
K0005829cellular_componentcytosol
K0006457biological_processprotein folding
K0009314biological_processresponse to radiation
K0009408biological_processresponse to heat
K0016020cellular_componentmembrane
K0016853molecular_functionisomerase activity
K0016887molecular_functionATP hydrolysis activity
K0019068biological_processvirion assembly
K0042026biological_processprotein refolding
K0042802molecular_functionidentical protein binding
K0051082molecular_functionunfolded protein binding
K0051085biological_processchaperone cofactor-dependent protein refolding
K0140662molecular_functionATP-dependent protein folding chaperone
K1990220cellular_componentGroEL-GroES complex
L0000287molecular_functionmagnesium ion binding
L0005515molecular_functionprotein binding
L0005524molecular_functionATP binding
L0005737cellular_componentcytoplasm
L0005829cellular_componentcytosol
L0006457biological_processprotein folding
L0009314biological_processresponse to radiation
L0009408biological_processresponse to heat
L0016020cellular_componentmembrane
L0016853molecular_functionisomerase activity
L0016887molecular_functionATP hydrolysis activity
L0019068biological_processvirion assembly
L0042026biological_processprotein refolding
L0042802molecular_functionidentical protein binding
L0051082molecular_functionunfolded protein binding
L0051085biological_processchaperone cofactor-dependent protein refolding
L0140662molecular_functionATP-dependent protein folding chaperone
L1990220cellular_componentGroEL-GroES complex
M0005515molecular_functionprotein binding
M0005524molecular_functionATP binding
M0005737cellular_componentcytoplasm
M0005829cellular_componentcytosol
M0006457biological_processprotein folding
M0009408biological_processresponse to heat
M0019068biological_processvirion assembly
M0042802molecular_functionidentical protein binding
M0044183molecular_functionprotein folding chaperone
M0046872molecular_functionmetal ion binding
M0051082molecular_functionunfolded protein binding
M0051085biological_processchaperone cofactor-dependent protein refolding
M0051087molecular_functionprotein-folding chaperone binding
M1990220cellular_componentGroEL-GroES complex
N0000287molecular_functionmagnesium ion binding
N0005515molecular_functionprotein binding
N0005524molecular_functionATP binding
N0005737cellular_componentcytoplasm
N0005829cellular_componentcytosol
N0006457biological_processprotein folding
N0009314biological_processresponse to radiation
N0009408biological_processresponse to heat
N0016020cellular_componentmembrane
N0016853molecular_functionisomerase activity
N0016887molecular_functionATP hydrolysis activity
N0019068biological_processvirion assembly
N0042026biological_processprotein refolding
N0042802molecular_functionidentical protein binding
N0051082molecular_functionunfolded protein binding
N0051085biological_processchaperone cofactor-dependent protein refolding
N0140662molecular_functionATP-dependent protein folding chaperone
N1990220cellular_componentGroEL-GroES complex
O0000287molecular_functionmagnesium ion binding
O0005515molecular_functionprotein binding
O0005524molecular_functionATP binding
O0005737cellular_componentcytoplasm
O0005829cellular_componentcytosol
O0006457biological_processprotein folding
O0009314biological_processresponse to radiation
O0009408biological_processresponse to heat
O0016020cellular_componentmembrane
O0016853molecular_functionisomerase activity
O0016887molecular_functionATP hydrolysis activity
O0019068biological_processvirion assembly
O0042026biological_processprotein refolding
O0042802molecular_functionidentical protein binding
O0051082molecular_functionunfolded protein binding
O0051085biological_processchaperone cofactor-dependent protein refolding
O0140662molecular_functionATP-dependent protein folding chaperone
O1990220cellular_componentGroEL-GroES complex
P0005515molecular_functionprotein binding
P0005524molecular_functionATP binding
P0005737cellular_componentcytoplasm
P0005829cellular_componentcytosol
P0006457biological_processprotein folding
P0009408biological_processresponse to heat
P0019068biological_processvirion assembly
P0042802molecular_functionidentical protein binding
P0044183molecular_functionprotein folding chaperone
P0046872molecular_functionmetal ion binding
P0051082molecular_functionunfolded protein binding
P0051085biological_processchaperone cofactor-dependent protein refolding
P0051087molecular_functionprotein-folding chaperone binding
P1990220cellular_componentGroEL-GroES complex
Q0000287molecular_functionmagnesium ion binding
Q0005515molecular_functionprotein binding
Q0005524molecular_functionATP binding
Q0005737cellular_componentcytoplasm
Q0005829cellular_componentcytosol
Q0006457biological_processprotein folding
Q0009314biological_processresponse to radiation
Q0009408biological_processresponse to heat
Q0016020cellular_componentmembrane
Q0016853molecular_functionisomerase activity
Q0016887molecular_functionATP hydrolysis activity
Q0019068biological_processvirion assembly
Q0042026biological_processprotein refolding
Q0042802molecular_functionidentical protein binding
Q0051082molecular_functionunfolded protein binding
Q0051085biological_processchaperone cofactor-dependent protein refolding
Q0140662molecular_functionATP-dependent protein folding chaperone
Q1990220cellular_componentGroEL-GroES complex
R0000287molecular_functionmagnesium ion binding
R0005515molecular_functionprotein binding
R0005524molecular_functionATP binding
R0005737cellular_componentcytoplasm
R0005829cellular_componentcytosol
R0006457biological_processprotein folding
R0009314biological_processresponse to radiation
R0009408biological_processresponse to heat
R0016020cellular_componentmembrane
R0016853molecular_functionisomerase activity
R0016887molecular_functionATP hydrolysis activity
R0019068biological_processvirion assembly
R0042026biological_processprotein refolding
R0042802molecular_functionidentical protein binding
R0051082molecular_functionunfolded protein binding
R0051085biological_processchaperone cofactor-dependent protein refolding
R0140662molecular_functionATP-dependent protein folding chaperone
R1990220cellular_componentGroEL-GroES complex
S0005515molecular_functionprotein binding
S0005524molecular_functionATP binding
S0005737cellular_componentcytoplasm
S0005829cellular_componentcytosol
S0006457biological_processprotein folding
S0009408biological_processresponse to heat
S0019068biological_processvirion assembly
S0042802molecular_functionidentical protein binding
S0044183molecular_functionprotein folding chaperone
S0046872molecular_functionmetal ion binding
S0051082molecular_functionunfolded protein binding
S0051085biological_processchaperone cofactor-dependent protein refolding
S0051087molecular_functionprotein-folding chaperone binding
S1990220cellular_componentGroEL-GroES complex
T0000287molecular_functionmagnesium ion binding
T0005515molecular_functionprotein binding
T0005524molecular_functionATP binding
T0005737cellular_componentcytoplasm
T0005829cellular_componentcytosol
T0006457biological_processprotein folding
T0009314biological_processresponse to radiation
T0009408biological_processresponse to heat
T0016020cellular_componentmembrane
T0016853molecular_functionisomerase activity
T0016887molecular_functionATP hydrolysis activity
T0019068biological_processvirion assembly
T0042026biological_processprotein refolding
T0042802molecular_functionidentical protein binding
T0051082molecular_functionunfolded protein binding
T0051085biological_processchaperone cofactor-dependent protein refolding
T0140662molecular_functionATP-dependent protein folding chaperone
T1990220cellular_componentGroEL-GroES complex
W0005515molecular_functionprotein binding
W0005524molecular_functionATP binding
W0005737cellular_componentcytoplasm
W0005829cellular_componentcytosol
W0006457biological_processprotein folding
W0009408biological_processresponse to heat
W0019068biological_processvirion assembly
W0042802molecular_functionidentical protein binding
W0044183molecular_functionprotein folding chaperone
W0046872molecular_functionmetal ion binding
W0051082molecular_functionunfolded protein binding
W0051085biological_processchaperone cofactor-dependent protein refolding
W0051087molecular_functionprotein-folding chaperone binding
W1990220cellular_componentGroEL-GroES complex
Functional Information from PROSITE/UniProt
site_idPS00296
Number of Residues12
DetailsCHAPERONINS_CPN60 Chaperonins cpn60 signature. AAVEEGVVaGGG
ChainResidueDetails
IALA405-GLY416

site_idPS00681
Number of Residues25
DetailsCHAPERONINS_CPN10 Chaperonins cpn10 signature. IrPLhDRVIVKrkevetksaGgIVL
ChainResidueDetails
WILE3-LEU27

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues7
DetailsMOD_RES: N6-succinyllysine => ECO:0000269|PubMed:21151122
ChainResidueDetails
WLYS34
GASP495
ATHR30
AASP87
AGLY415
AASN479
AASP495
CTHR30
CASP87
CGLY415
CASN479
BLYS34
CASP495
DTHR30
DASP87
DGLY415
DASN479
DASP495
FTHR30
FASP87
FGLY415
FASN479
ELYS34
FASP495
HTHR30
HASP87
HGLY415
HASN479
HASP495
KTHR30
KASP87
KGLY415
KASN479
JLYS34
KASP495
LTHR30
LASP87
LGLY415
LASN479
LASP495
NTHR30
NASP87
NGLY415
NASN479
MLYS34
NASP495
OTHR30
OASP87
OGLY415
OASN479
OASP495
QTHR30
QASP87
QGLY415
QASN479
PLYS34
QASP495
RTHR30
RASP87
RGLY415
RASN479
RASP495
TTHR30
TASP87
TGLY415
TASN479
SLYS34
TASP495
GGLY415
GASN479

site_idSWS_FT_FI2
Number of Residues14
DetailsBINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00600, ECO:0000269|PubMed:25174333, ECO:0000305|PubMed:14517228, ECO:0000305|PubMed:9285585, ECO:0007744|PDB:1AON, ECO:0007744|PDB:1PF9, ECO:0007744|PDB:3WVL
ChainResidueDetails
ILYS51
NLYS51
OLYS51
QLYS51
RLYS51
TLYS51
GLYS51
ALYS51
CLYS51
DLYS51
FLYS51
HLYS51
KLYS51
LLYS51

site_idSWS_FT_FI3
Number of Residues70
DetailsMOD_RES: N6-succinyllysine => ECO:0000269|PubMed:21151122
ChainResidueDetails
ILYS34
GLYS390
ALYS34
ALYS51
ALYS277
ALYS321
ALYS390
CLYS34
CLYS51
CLYS277
CLYS321
ILYS51
CLYS390
DLYS34
DLYS51
DLYS277
DLYS321
DLYS390
FLYS34
FLYS51
FLYS277
FLYS321
ILYS277
FLYS390
HLYS34
HLYS51
HLYS277
HLYS321
HLYS390
KLYS34
KLYS51
KLYS277
KLYS321
ILYS321
KLYS390
LLYS34
LLYS51
LLYS277
LLYS321
LLYS390
NLYS34
NLYS51
NLYS277
NLYS321
ILYS390
NLYS390
OLYS34
OLYS51
OLYS277
OLYS321
OLYS390
QLYS34
QLYS51
QLYS277
QLYS321
GLYS34
QLYS390
RLYS34
RLYS51
RLYS277
RLYS321
RLYS390
TLYS34
TLYS51
TLYS277
TLYS321
GLYS51
TLYS390
GLYS277
GLYS321

site_idSWS_FT_FI4
Number of Residues14
DetailsMOD_RES: N6-succinyllysine; alternate => ECO:0000269|PubMed:21151122
ChainResidueDetails
ILYS117
NLYS117
OLYS117
QLYS117
RLYS117
TLYS117
GLYS117
ALYS117
CLYS117
DLYS117
FLYS117
HLYS117
KLYS117
LLYS117

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PDB entries from 2024-07-17

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