8BHB

GABA-A receptor a5 homomer - a5V3 - RO154513

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004888	molecular_function	transmembrane signaling receptor activity
A	0004890	molecular_function	GABA-A receptor activity
A	0005216	molecular_function	monoatomic ion channel activity
A	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
A	0006811	biological_process	monoatomic ion transport
A	0016020	cellular_component	membrane
A	0034220	biological_process	monoatomic ion transmembrane transport
B	0004888	molecular_function	transmembrane signaling receptor activity
B	0004890	molecular_function	GABA-A receptor activity
B	0005216	molecular_function	monoatomic ion channel activity
B	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
B	0006811	biological_process	monoatomic ion transport
B	0016020	cellular_component	membrane
B	0034220	biological_process	monoatomic ion transmembrane transport
C	0004888	molecular_function	transmembrane signaling receptor activity
C	0004890	molecular_function	GABA-A receptor activity
C	0005216	molecular_function	monoatomic ion channel activity
C	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
C	0006811	biological_process	monoatomic ion transport
C	0016020	cellular_component	membrane
C	0034220	biological_process	monoatomic ion transmembrane transport
D	0004888	molecular_function	transmembrane signaling receptor activity
D	0004890	molecular_function	GABA-A receptor activity
D	0005216	molecular_function	monoatomic ion channel activity
D	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
D	0006811	biological_process	monoatomic ion transport
D	0016020	cellular_component	membrane
D	0034220	biological_process	monoatomic ion transmembrane transport
E	0004888	molecular_function	transmembrane signaling receptor activity
E	0004890	molecular_function	GABA-A receptor activity
E	0005216	molecular_function	monoatomic ion channel activity
E	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
E	0006811	biological_process	monoatomic ion transport
E	0016020	cellular_component	membrane
E	0034220	biological_process	monoatomic ion transmembrane transport

Functional Information from PROSITE/UniProt

site_id	PS00236
Number of Residues	15
Details	NEUROTR_ION_CHANNEL Neurotransmitter-gated ion-channels signature. CpMdLedFPmDeqnC

Chain	Residue	Details
A	CYS142-CYS156

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1135
Details	TOPO_DOM: Extracellular => ECO:0000255

Chain	Residue	Details
A	GLN1-TYR228
B	GLN1-TYR228
C	GLN1-TYR228
D	GLN1-TYR228
E	GLN1-TYR228

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site_id	SWS_FT_FI2
Number of Residues	315
Details	TRANSMEM: Helical => ECO:0000255

Chain	Residue	Details
A	PHE229-LEU250
D	PHE229-LEU250
D	VAL255-ALA276
D	MET397-LEU418
E	PHE229-LEU250
E	VAL255-ALA276
E	MET397-LEU418
A	VAL255-ALA276
A	MET397-LEU418
B	PHE229-LEU250
B	VAL255-ALA276
B	MET397-LEU418
C	PHE229-LEU250
C	VAL255-ALA276
C	MET397-LEU418

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site_id	SWS_FT_FI3
Number of Residues	20
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
A	ASN14
C	TRP114
C	ASN176
C	ASN205
D	ASN14
D	TRP114
D	ASN176
D	ASN205
E	ASN14
E	TRP114
E	ASN176
A	TRP114
E	ASN205
A	ASN176
A	ASN205
B	ASN14
B	TRP114
B	ASN176
B	ASN205
C	ASN14

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