8AOX

CryoEM structure of the Chikungunya virus nsP1 capping pores in complex with SAM

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0006396	biological_process	RNA processing
A	0008174	molecular_function	mRNA methyltransferase activity
A	0016556	biological_process	mRNA modification
BA	0003723	molecular_function	RNA binding
BA	0006396	biological_process	RNA processing
BA	0008174	molecular_function	mRNA methyltransferase activity
BA	0016556	biological_process	mRNA modification
C	0003723	molecular_function	RNA binding
C	0006396	biological_process	RNA processing
C	0008174	molecular_function	mRNA methyltransferase activity
C	0016556	biological_process	mRNA modification
DA	0003723	molecular_function	RNA binding
DA	0006396	biological_process	RNA processing
DA	0008174	molecular_function	mRNA methyltransferase activity
DA	0016556	biological_process	mRNA modification
E	0003723	molecular_function	RNA binding
E	0006396	biological_process	RNA processing
E	0008174	molecular_function	mRNA methyltransferase activity
E	0016556	biological_process	mRNA modification
FA	0003723	molecular_function	RNA binding
FA	0006396	biological_process	RNA processing
FA	0008174	molecular_function	mRNA methyltransferase activity
FA	0016556	biological_process	mRNA modification
G	0003723	molecular_function	RNA binding
G	0006396	biological_process	RNA processing
G	0008174	molecular_function	mRNA methyltransferase activity
G	0016556	biological_process	mRNA modification
HA	0003723	molecular_function	RNA binding
HA	0006396	biological_process	RNA processing
HA	0008174	molecular_function	mRNA methyltransferase activity
HA	0016556	biological_process	mRNA modification
I	0003723	molecular_function	RNA binding
I	0006396	biological_process	RNA processing
I	0008174	molecular_function	mRNA methyltransferase activity
I	0016556	biological_process	mRNA modification
JA	0003723	molecular_function	RNA binding
JA	0006396	biological_process	RNA processing
JA	0008174	molecular_function	mRNA methyltransferase activity
JA	0016556	biological_process	mRNA modification
K	0003723	molecular_function	RNA binding
K	0006396	biological_process	RNA processing
K	0008174	molecular_function	mRNA methyltransferase activity
K	0016556	biological_process	mRNA modification
LA	0003723	molecular_function	RNA binding
LA	0006396	biological_process	RNA processing
LA	0008174	molecular_function	mRNA methyltransferase activity
LA	0016556	biological_process	mRNA modification
M	0003723	molecular_function	RNA binding
M	0006396	biological_process	RNA processing
M	0008174	molecular_function	mRNA methyltransferase activity
M	0016556	biological_process	mRNA modification
NA	0003723	molecular_function	RNA binding
NA	0006396	biological_process	RNA processing
NA	0008174	molecular_function	mRNA methyltransferase activity
NA	0016556	biological_process	mRNA modification
O	0003723	molecular_function	RNA binding
O	0006396	biological_process	RNA processing
O	0008174	molecular_function	mRNA methyltransferase activity
O	0016556	biological_process	mRNA modification
PA	0003723	molecular_function	RNA binding
PA	0006396	biological_process	RNA processing
PA	0008174	molecular_function	mRNA methyltransferase activity
PA	0016556	biological_process	mRNA modification
Q	0003723	molecular_function	RNA binding
Q	0006396	biological_process	RNA processing
Q	0008174	molecular_function	mRNA methyltransferase activity
Q	0016556	biological_process	mRNA modification
RA	0003723	molecular_function	RNA binding
RA	0006396	biological_process	RNA processing
RA	0008174	molecular_function	mRNA methyltransferase activity
RA	0016556	biological_process	mRNA modification
S	0003723	molecular_function	RNA binding
S	0006396	biological_process	RNA processing
S	0008174	molecular_function	mRNA methyltransferase activity
S	0016556	biological_process	mRNA modification
TA	0003723	molecular_function	RNA binding
TA	0006396	biological_process	RNA processing
TA	0008174	molecular_function	mRNA methyltransferase activity
TA	0016556	biological_process	mRNA modification
V	0003723	molecular_function	RNA binding
V	0006396	biological_process	RNA processing
V	0008174	molecular_function	mRNA methyltransferase activity
V	0016556	biological_process	mRNA modification
VA	0003723	molecular_function	RNA binding
VA	0006396	biological_process	RNA processing
VA	0008174	molecular_function	mRNA methyltransferase activity
VA	0016556	biological_process	mRNA modification
X	0003723	molecular_function	RNA binding
X	0006396	biological_process	RNA processing
X	0008174	molecular_function	mRNA methyltransferase activity
X	0016556	biological_process	mRNA modification
Z	0003723	molecular_function	RNA binding
Z	0006396	biological_process	RNA processing
Z	0008174	molecular_function	mRNA methyltransferase activity
Z	0016556	biological_process	mRNA modification

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5544
Details	Domain: {"description":"Alphavirus-like MT","evidences":[{"source":"PROSITE-ProRule","id":"PRU01079","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	24
Details	Active site: {"description":"For mRNA-capping enzyme nsP1 activity","evidences":[{"source":"PubMed","id":"33730549","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	96
Details	Binding site: {"evidences":[{"source":"PubMed","id":"33730549","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	24
Details	Site: {"description":"Involved in the phosphoramide link with 7-methyl-GMP","evidences":[{"source":"UniProtKB","id":"P27282","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	48
Details	Lipidation: {"description":"S-palmitoyl cysteine; by host","evidences":[{"source":"PubMed","id":"30404808","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---