8AMQ
Crystal structure of the complex CYP143-FdxE from M. tuberculosis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| A | 0020037 | molecular_function | heme binding |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051538 | molecular_function | 3 iron, 4 sulfur cluster binding |
Functional Information from PROSITE/UniProt
| site_id | PS00086 |
| Number of Residues | 10 |
| Details | CYTOCHROME_P450 Cytochrome P450 cysteine heme-iron ligand signature. FGgGPHRCLG |
| Chain | Residue | Details |
| A | PHE1335-GLY1344 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 5 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:36699703, ECO:0007744|PDB:8AMQ |
| Chain | Residue | Details |
| A | CYS10 | |
| A | VAL11 | |
| A | GLN15 | |
| A | CYS16 | |
| A | CYS54 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:36699703, ECO:0007744|PDB:8AMO, ECO:0007744|PDB:8AMQ |
| Chain | Residue | Details |
| A | HIS1091 | |
| A | ARG1095 | |
| A | ARG1284 | |
| A | HIS1340 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | BINDING: axial binding residue => ECO:0000269|PubMed:36699703, ECO:0007744|PDB:8AMO, ECO:0007744|PDB:8AMQ |
| Chain | Residue | Details |
| A | CYS1342 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: N-acetylthreonine => ECO:0007744|PubMed:21969609 |
| Chain | Residue | Details |
| A | THR1002 |
