8AMO
Crystal structure of M. tuberculosis CYP143
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004497 | molecular_function | monooxygenase activity |
A | 0005506 | molecular_function | iron ion binding |
A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
A | 0020037 | molecular_function | heme binding |
A | 0046872 | molecular_function | metal ion binding |
Functional Information from PROSITE/UniProt
site_id | PS00086 |
Number of Residues | 10 |
Details | CYTOCHROME_P450 Cytochrome P450 cysteine heme-iron ligand signature. FGgGPHRCLG |
Chain | Residue | Details |
A | PHE335-GLY344 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 4 |
Details | BINDING: BINDING => ECO:0000269|PubMed:36699703, ECO:0007744|PDB:8AMO, ECO:0007744|PDB:8AMQ |
Chain | Residue | Details |
A | HIS91 | |
A | ARG95 | |
A | ARG284 | |
A | HIS340 |
site_id | SWS_FT_FI2 |
Number of Residues | 1 |
Details | BINDING: axial binding residue => ECO:0000269|PubMed:36699703, ECO:0007744|PDB:8AMO, ECO:0007744|PDB:8AMQ |
Chain | Residue | Details |
A | CYS342 |
site_id | SWS_FT_FI3 |
Number of Residues | 1 |
Details | MOD_RES: N-acetylthreonine => ECO:0007744|PubMed:21969609 |
Chain | Residue | Details |
A | THR2 |