8AJV

Crystal structure of the Q65N mutant of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa crystallized in the presence of K+ cations

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
AAA	0004013	molecular_function	adenosylhomocysteinase activity
AAA	0005737	cellular_component	cytoplasm
AAA	0005829	cellular_component	cytosol
AAA	0006730	biological_process	one-carbon metabolic process
AAA	0016787	molecular_function	hydrolase activity
AAA	0033353	biological_process	S-adenosylmethionine cycle
AAA	0071269	biological_process	L-homocysteine biosynthetic process
BBB	0004013	molecular_function	adenosylhomocysteinase activity
BBB	0005737	cellular_component	cytoplasm
BBB	0005829	cellular_component	cytosol
BBB	0006730	biological_process	one-carbon metabolic process
BBB	0016787	molecular_function	hydrolase activity
BBB	0033353	biological_process	S-adenosylmethionine cycle
BBB	0071269	biological_process	L-homocysteine biosynthetic process
CCC	0004013	molecular_function	adenosylhomocysteinase activity
CCC	0005737	cellular_component	cytoplasm
CCC	0005829	cellular_component	cytosol
CCC	0006730	biological_process	one-carbon metabolic process
CCC	0016787	molecular_function	hydrolase activity
CCC	0033353	biological_process	S-adenosylmethionine cycle
CCC	0071269	biological_process	L-homocysteine biosynthetic process
DDD	0004013	molecular_function	adenosylhomocysteinase activity
DDD	0005737	cellular_component	cytoplasm
DDD	0005829	cellular_component	cytosol
DDD	0006730	biological_process	one-carbon metabolic process
DDD	0016787	molecular_function	hydrolase activity
DDD	0033353	biological_process	S-adenosylmethionine cycle
DDD	0071269	biological_process	L-homocysteine biosynthetic process
FFF	0004013	molecular_function	adenosylhomocysteinase activity
FFF	0005737	cellular_component	cytoplasm
FFF	0005829	cellular_component	cytosol
FFF	0006730	biological_process	one-carbon metabolic process
FFF	0016787	molecular_function	hydrolase activity
FFF	0033353	biological_process	S-adenosylmethionine cycle
FFF	0071269	biological_process	L-homocysteine biosynthetic process
GGG	0004013	molecular_function	adenosylhomocysteinase activity
GGG	0005737	cellular_component	cytoplasm
GGG	0005829	cellular_component	cytosol
GGG	0006730	biological_process	one-carbon metabolic process
GGG	0016787	molecular_function	hydrolase activity
GGG	0033353	biological_process	S-adenosylmethionine cycle
GGG	0071269	biological_process	L-homocysteine biosynthetic process
HHH	0004013	molecular_function	adenosylhomocysteinase activity
HHH	0005737	cellular_component	cytoplasm
HHH	0005829	cellular_component	cytosol
HHH	0006730	biological_process	one-carbon metabolic process
HHH	0016787	molecular_function	hydrolase activity
HHH	0033353	biological_process	S-adenosylmethionine cycle
HHH	0071269	biological_process	L-homocysteine biosynthetic process
III	0004013	molecular_function	adenosylhomocysteinase activity
III	0005737	cellular_component	cytoplasm
III	0005829	cellular_component	cytosol
III	0006730	biological_process	one-carbon metabolic process
III	0016787	molecular_function	hydrolase activity
III	0033353	biological_process	S-adenosylmethionine cycle
III	0071269	biological_process	L-homocysteine biosynthetic process

Functional Information from PROSITE/UniProt

site_id	PS00738
Number of Residues	15
Details	ADOHCYASE_1 S-adenosyl-L-homocysteine hydrolase signature 1. SCNiFSTQDqAAAAI

Chain	Residue	Details
AAA	SER84-ILE98

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site_id	PS00739
Number of Residues	17
Details	ADOHCYASE_2 S-adenosyl-L-homocysteine hydrolase signature 2. GKqalViGYGdVGKGs.S

Chain	Residue	Details
AAA	GLY221-SER237

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	96
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00563

Chain	Residue	Details
AAA	THR63
AAA	ASN300
AAA	ILE321
AAA	ASN375
BBB	THR63
BBB	ASP139
BBB	GLU164
BBB	THR165
BBB	LYS194
BBB	ASP198
BBB	ASN199
AAA	ASP139
BBB	GLY228
BBB	GLU251
BBB	ASN300
BBB	ILE321
BBB	ASN375
CCC	THR63
CCC	ASP139
CCC	GLU164
CCC	THR165
CCC	LYS194
AAA	GLU164
CCC	ASP198
CCC	ASN199
CCC	GLY228
CCC	GLU251
CCC	ASN300
CCC	ILE321
CCC	ASN375
DDD	THR63
DDD	ASP139
DDD	GLU164
AAA	THR165
DDD	THR165
DDD	LYS194
DDD	ASP198
DDD	ASN199
DDD	GLY228
DDD	GLU251
DDD	ASN300
DDD	ILE321
DDD	ASN375
FFF	THR63
AAA	LYS194
FFF	ASP139
FFF	GLU164
FFF	THR165
FFF	LYS194
FFF	ASP198
FFF	ASN199
FFF	GLY228
FFF	GLU251
FFF	ASN300
FFF	ILE321
AAA	ASP198
FFF	ASN375
GGG	THR63
GGG	ASP139
GGG	GLU164
GGG	THR165
GGG	LYS194
GGG	ASP198
GGG	ASN199
GGG	GLY228
GGG	GLU251
AAA	ASN199
GGG	ASN300
GGG	ILE321
GGG	ASN375
HHH	THR63
HHH	ASP139
HHH	GLU164
HHH	THR165
HHH	LYS194
HHH	ASP198
HHH	ASN199
AAA	GLY228
HHH	GLY228
HHH	GLU251
HHH	ASN300
HHH	ILE321
HHH	ASN375
III	THR63
III	ASP139
III	GLU164
III	THR165
III	LYS194
AAA	GLU251
III	ASP198
III	ASN199
III	GLY228
III	GLU251
III	ASN300
III	ILE321
III	ASN375

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