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8AJV

Crystal structure of the Q65N mutant of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa crystallized in the presence of K+ cations

This is a non-PDB format compatible entry.
Functional Information from GO Data
ChainGOidnamespacecontents
AAA0004013molecular_functionadenosylhomocysteinase activity
AAA0005737cellular_componentcytoplasm
AAA0005829cellular_componentcytosol
AAA0006730biological_processone-carbon metabolic process
AAA0016787molecular_functionhydrolase activity
AAA0033353biological_processS-adenosylmethionine cycle
AAA0071269biological_processL-homocysteine biosynthetic process
BBB0004013molecular_functionadenosylhomocysteinase activity
BBB0005737cellular_componentcytoplasm
BBB0005829cellular_componentcytosol
BBB0006730biological_processone-carbon metabolic process
BBB0016787molecular_functionhydrolase activity
BBB0033353biological_processS-adenosylmethionine cycle
BBB0071269biological_processL-homocysteine biosynthetic process
CCC0004013molecular_functionadenosylhomocysteinase activity
CCC0005737cellular_componentcytoplasm
CCC0005829cellular_componentcytosol
CCC0006730biological_processone-carbon metabolic process
CCC0016787molecular_functionhydrolase activity
CCC0033353biological_processS-adenosylmethionine cycle
CCC0071269biological_processL-homocysteine biosynthetic process
DDD0004013molecular_functionadenosylhomocysteinase activity
DDD0005737cellular_componentcytoplasm
DDD0005829cellular_componentcytosol
DDD0006730biological_processone-carbon metabolic process
DDD0016787molecular_functionhydrolase activity
DDD0033353biological_processS-adenosylmethionine cycle
DDD0071269biological_processL-homocysteine biosynthetic process
FFF0004013molecular_functionadenosylhomocysteinase activity
FFF0005737cellular_componentcytoplasm
FFF0005829cellular_componentcytosol
FFF0006730biological_processone-carbon metabolic process
FFF0016787molecular_functionhydrolase activity
FFF0033353biological_processS-adenosylmethionine cycle
FFF0071269biological_processL-homocysteine biosynthetic process
GGG0004013molecular_functionadenosylhomocysteinase activity
GGG0005737cellular_componentcytoplasm
GGG0005829cellular_componentcytosol
GGG0006730biological_processone-carbon metabolic process
GGG0016787molecular_functionhydrolase activity
GGG0033353biological_processS-adenosylmethionine cycle
GGG0071269biological_processL-homocysteine biosynthetic process
HHH0004013molecular_functionadenosylhomocysteinase activity
HHH0005737cellular_componentcytoplasm
HHH0005829cellular_componentcytosol
HHH0006730biological_processone-carbon metabolic process
HHH0016787molecular_functionhydrolase activity
HHH0033353biological_processS-adenosylmethionine cycle
HHH0071269biological_processL-homocysteine biosynthetic process
III0004013molecular_functionadenosylhomocysteinase activity
III0005737cellular_componentcytoplasm
III0005829cellular_componentcytosol
III0006730biological_processone-carbon metabolic process
III0016787molecular_functionhydrolase activity
III0033353biological_processS-adenosylmethionine cycle
III0071269biological_processL-homocysteine biosynthetic process
Functional Information from PROSITE/UniProt
site_idPS00738
Number of Residues15
DetailsADOHCYASE_1 S-adenosyl-L-homocysteine hydrolase signature 1. SCNiFSTQDqAAAAI
ChainResidueDetails
AAASER84-ILE98

site_idPS00739
Number of Residues17
DetailsADOHCYASE_2 S-adenosyl-L-homocysteine hydrolase signature 2. GKqalViGYGdVGKGs.S
ChainResidueDetails
AAAGLY221-SER237

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues144
DetailsBinding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00563","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

243531

PDB entries from 2025-10-22

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