8AJU
Crystal structure of the Q65A mutant of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa cocrystallized with adenosine in the presence of K+ cations
This is a non-PDB format compatible entry.
Functional Information from GO Data
Chain | GOid | namespace | contents |
AAA | 0004013 | molecular_function | adenosylhomocysteinase activity |
AAA | 0005737 | cellular_component | cytoplasm |
AAA | 0005829 | cellular_component | cytosol |
AAA | 0006730 | biological_process | one-carbon metabolic process |
AAA | 0016787 | molecular_function | hydrolase activity |
AAA | 0033353 | biological_process | S-adenosylmethionine cycle |
AAA | 0071269 | biological_process | L-homocysteine biosynthetic process |
CCC | 0004013 | molecular_function | adenosylhomocysteinase activity |
CCC | 0005737 | cellular_component | cytoplasm |
CCC | 0005829 | cellular_component | cytosol |
CCC | 0006730 | biological_process | one-carbon metabolic process |
CCC | 0016787 | molecular_function | hydrolase activity |
CCC | 0033353 | biological_process | S-adenosylmethionine cycle |
CCC | 0071269 | biological_process | L-homocysteine biosynthetic process |
Functional Information from PROSITE/UniProt
site_id | PS00738 |
Number of Residues | 15 |
Details | ADOHCYASE_1 S-adenosyl-L-homocysteine hydrolase signature 1. SCNiFSTQDqAAAAI |
Chain | Residue | Details |
AAA | SER84-ILE98 |
site_id | PS00739 |
Number of Residues | 17 |
Details | ADOHCYASE_2 S-adenosyl-L-homocysteine hydrolase signature 2. GKqalViGYGdVGKGs.S |
Chain | Residue | Details |
AAA | GLY221-SER237 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 24 |
Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00563 |
Chain | Residue | Details |
AAA | THR63 | |
AAA | ASN300 | |
AAA | ILE321 | |
AAA | ASN375 | |
CCC | THR63 | |
CCC | ASP139 | |
CCC | GLU164 | |
CCC | THR165 | |
CCC | LYS194 | |
CCC | ASP198 | |
CCC | ASN199 | |
AAA | ASP139 | |
CCC | GLY228 | |
CCC | GLU251 | |
CCC | ASN300 | |
CCC | ILE321 | |
CCC | ASN375 | |
AAA | GLU164 | |
AAA | THR165 | |
AAA | LYS194 | |
AAA | ASP198 | |
AAA | ASN199 | |
AAA | GLY228 | |
AAA | GLU251 |