8AJU

Crystal structure of the Q65A mutant of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa cocrystallized with adenosine in the presence of K+ cations

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
AAA	0004013	molecular_function	adenosylhomocysteinase activity
AAA	0005737	cellular_component	cytoplasm
AAA	0005829	cellular_component	cytosol
AAA	0006730	biological_process	one-carbon metabolic process
AAA	0016787	molecular_function	hydrolase activity
AAA	0033353	biological_process	S-adenosylmethionine cycle
CCC	0004013	molecular_function	adenosylhomocysteinase activity
CCC	0005737	cellular_component	cytoplasm
CCC	0005829	cellular_component	cytosol
CCC	0006730	biological_process	one-carbon metabolic process
CCC	0016787	molecular_function	hydrolase activity
CCC	0033353	biological_process	S-adenosylmethionine cycle

Functional Information from PROSITE/UniProt

site_id	PS00738
Number of Residues	15
Details	ADOHCYASE_1 S-adenosyl-L-homocysteine hydrolase signature 1. SCNiFSTQDqAAAAI

Chain	Residue	Details
AAA	SER84-ILE98

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site_id	PS00739
Number of Residues	17
Details	ADOHCYASE_2 S-adenosyl-L-homocysteine hydrolase signature 2. GKqalViGYGdVGKGs.S

Chain	Residue	Details
AAA	GLY221-SER237

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	24
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00563

Chain	Residue	Details
AAA	THR63
AAA	ASP139
AAA	GLU164
AAA	THR165
AAA	LYS194
AAA	ASP198
AAA	ASN199
AAA	GLY228
AAA	GLU251
AAA	ASN300
AAA	ILE321
AAA	ASN375
CCC	THR63
CCC	ASP139
CCC	GLU164
CCC	THR165
CCC	LYS194
CCC	ASP198
CCC	ASN199
CCC	GLY228
CCC	GLU251
CCC	ASN300
CCC	ILE321
CCC	ASN375

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