8AEY

3 A CRYO-EM STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS FERRITIN FROM TIMEPIX3 detector

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001666	biological_process	response to hypoxia
A	0004322	molecular_function	ferroxidase activity
A	0005576	cellular_component	extracellular region
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0006826	biological_process	iron ion transport
A	0006879	biological_process	intracellular iron ion homeostasis
A	0006880	biological_process	intracellular sequestering of iron ion
A	0008198	molecular_function	ferrous iron binding
A	0008199	molecular_function	ferric iron binding
A	0009274	cellular_component	peptidoglycan-based cell wall
A	0016491	molecular_function	oxidoreductase activity
A	0046872	molecular_function	metal ion binding
A	0051409	biological_process	response to nitrosative stress
A	0140315	molecular_function	iron ion sequestering activity
A	0140737	cellular_component	encapsulin nanocompartment
B	0001666	biological_process	response to hypoxia
B	0004322	molecular_function	ferroxidase activity
B	0005576	cellular_component	extracellular region
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005886	cellular_component	plasma membrane
B	0006826	biological_process	iron ion transport
B	0006879	biological_process	intracellular iron ion homeostasis
B	0006880	biological_process	intracellular sequestering of iron ion
B	0008198	molecular_function	ferrous iron binding
B	0008199	molecular_function	ferric iron binding
B	0009274	cellular_component	peptidoglycan-based cell wall
B	0016491	molecular_function	oxidoreductase activity
B	0046872	molecular_function	metal ion binding
B	0051409	biological_process	response to nitrosative stress
B	0140315	molecular_function	iron ion sequestering activity
B	0140737	cellular_component	encapsulin nanocompartment
C	0001666	biological_process	response to hypoxia
C	0004322	molecular_function	ferroxidase activity
C	0005576	cellular_component	extracellular region
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0005886	cellular_component	plasma membrane
C	0006826	biological_process	iron ion transport
C	0006879	biological_process	intracellular iron ion homeostasis
C	0006880	biological_process	intracellular sequestering of iron ion
C	0008198	molecular_function	ferrous iron binding
C	0008199	molecular_function	ferric iron binding
C	0009274	cellular_component	peptidoglycan-based cell wall
C	0016491	molecular_function	oxidoreductase activity
C	0046872	molecular_function	metal ion binding
C	0051409	biological_process	response to nitrosative stress
C	0140315	molecular_function	iron ion sequestering activity
C	0140737	cellular_component	encapsulin nanocompartment
D	0001666	biological_process	response to hypoxia
D	0004322	molecular_function	ferroxidase activity
D	0005576	cellular_component	extracellular region
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0005886	cellular_component	plasma membrane
D	0006826	biological_process	iron ion transport
D	0006879	biological_process	intracellular iron ion homeostasis
D	0006880	biological_process	intracellular sequestering of iron ion
D	0008198	molecular_function	ferrous iron binding
D	0008199	molecular_function	ferric iron binding
D	0009274	cellular_component	peptidoglycan-based cell wall
D	0016491	molecular_function	oxidoreductase activity
D	0046872	molecular_function	metal ion binding
D	0051409	biological_process	response to nitrosative stress
D	0140315	molecular_function	iron ion sequestering activity
D	0140737	cellular_component	encapsulin nanocompartment
E	0001666	biological_process	response to hypoxia
E	0004322	molecular_function	ferroxidase activity
E	0005576	cellular_component	extracellular region
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0005886	cellular_component	plasma membrane
E	0006826	biological_process	iron ion transport
E	0006879	biological_process	intracellular iron ion homeostasis
E	0006880	biological_process	intracellular sequestering of iron ion
E	0008198	molecular_function	ferrous iron binding
E	0008199	molecular_function	ferric iron binding
E	0009274	cellular_component	peptidoglycan-based cell wall
E	0016491	molecular_function	oxidoreductase activity
E	0046872	molecular_function	metal ion binding
E	0051409	biological_process	response to nitrosative stress
E	0140315	molecular_function	iron ion sequestering activity
E	0140737	cellular_component	encapsulin nanocompartment
F	0001666	biological_process	response to hypoxia
F	0004322	molecular_function	ferroxidase activity
F	0005576	cellular_component	extracellular region
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0005886	cellular_component	plasma membrane
F	0006826	biological_process	iron ion transport
F	0006879	biological_process	intracellular iron ion homeostasis
F	0006880	biological_process	intracellular sequestering of iron ion
F	0008198	molecular_function	ferrous iron binding
F	0008199	molecular_function	ferric iron binding
F	0009274	cellular_component	peptidoglycan-based cell wall
F	0016491	molecular_function	oxidoreductase activity
F	0046872	molecular_function	metal ion binding
F	0051409	biological_process	response to nitrosative stress
F	0140315	molecular_function	iron ion sequestering activity
F	0140737	cellular_component	encapsulin nanocompartment
G	0001666	biological_process	response to hypoxia
G	0004322	molecular_function	ferroxidase activity
G	0005576	cellular_component	extracellular region
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0005886	cellular_component	plasma membrane
G	0006826	biological_process	iron ion transport
G	0006879	biological_process	intracellular iron ion homeostasis
G	0006880	biological_process	intracellular sequestering of iron ion
G	0008198	molecular_function	ferrous iron binding
G	0008199	molecular_function	ferric iron binding
G	0009274	cellular_component	peptidoglycan-based cell wall
G	0016491	molecular_function	oxidoreductase activity
G	0046872	molecular_function	metal ion binding
G	0051409	biological_process	response to nitrosative stress
G	0140315	molecular_function	iron ion sequestering activity
G	0140737	cellular_component	encapsulin nanocompartment
H	0001666	biological_process	response to hypoxia
H	0004322	molecular_function	ferroxidase activity
H	0005576	cellular_component	extracellular region
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0005886	cellular_component	plasma membrane
H	0006826	biological_process	iron ion transport
H	0006879	biological_process	intracellular iron ion homeostasis
H	0006880	biological_process	intracellular sequestering of iron ion
H	0008198	molecular_function	ferrous iron binding
H	0008199	molecular_function	ferric iron binding
H	0009274	cellular_component	peptidoglycan-based cell wall
H	0016491	molecular_function	oxidoreductase activity
H	0046872	molecular_function	metal ion binding
H	0051409	biological_process	response to nitrosative stress
H	0140315	molecular_function	iron ion sequestering activity
H	0140737	cellular_component	encapsulin nanocompartment
I	0001666	biological_process	response to hypoxia
I	0004322	molecular_function	ferroxidase activity
I	0005576	cellular_component	extracellular region
I	0005737	cellular_component	cytoplasm
I	0005829	cellular_component	cytosol
I	0005886	cellular_component	plasma membrane
I	0006826	biological_process	iron ion transport
I	0006879	biological_process	intracellular iron ion homeostasis
I	0006880	biological_process	intracellular sequestering of iron ion
I	0008198	molecular_function	ferrous iron binding
I	0008199	molecular_function	ferric iron binding
I	0009274	cellular_component	peptidoglycan-based cell wall
I	0016491	molecular_function	oxidoreductase activity
I	0046872	molecular_function	metal ion binding
I	0051409	biological_process	response to nitrosative stress
I	0140315	molecular_function	iron ion sequestering activity
I	0140737	cellular_component	encapsulin nanocompartment
J	0001666	biological_process	response to hypoxia
J	0004322	molecular_function	ferroxidase activity
J	0005576	cellular_component	extracellular region
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0005886	cellular_component	plasma membrane
J	0006826	biological_process	iron ion transport
J	0006879	biological_process	intracellular iron ion homeostasis
J	0006880	biological_process	intracellular sequestering of iron ion
J	0008198	molecular_function	ferrous iron binding
J	0008199	molecular_function	ferric iron binding
J	0009274	cellular_component	peptidoglycan-based cell wall
J	0016491	molecular_function	oxidoreductase activity
J	0046872	molecular_function	metal ion binding
J	0051409	biological_process	response to nitrosative stress
J	0140315	molecular_function	iron ion sequestering activity
J	0140737	cellular_component	encapsulin nanocompartment
K	0001666	biological_process	response to hypoxia
K	0004322	molecular_function	ferroxidase activity
K	0005576	cellular_component	extracellular region
K	0005737	cellular_component	cytoplasm
K	0005829	cellular_component	cytosol
K	0005886	cellular_component	plasma membrane
K	0006826	biological_process	iron ion transport
K	0006879	biological_process	intracellular iron ion homeostasis
K	0006880	biological_process	intracellular sequestering of iron ion
K	0008198	molecular_function	ferrous iron binding
K	0008199	molecular_function	ferric iron binding
K	0009274	cellular_component	peptidoglycan-based cell wall
K	0016491	molecular_function	oxidoreductase activity
K	0046872	molecular_function	metal ion binding
K	0051409	biological_process	response to nitrosative stress
K	0140315	molecular_function	iron ion sequestering activity
K	0140737	cellular_component	encapsulin nanocompartment
L	0001666	biological_process	response to hypoxia
L	0004322	molecular_function	ferroxidase activity
L	0005576	cellular_component	extracellular region
L	0005737	cellular_component	cytoplasm
L	0005829	cellular_component	cytosol
L	0005886	cellular_component	plasma membrane
L	0006826	biological_process	iron ion transport
L	0006879	biological_process	intracellular iron ion homeostasis
L	0006880	biological_process	intracellular sequestering of iron ion
L	0008198	molecular_function	ferrous iron binding
L	0008199	molecular_function	ferric iron binding
L	0009274	cellular_component	peptidoglycan-based cell wall
L	0016491	molecular_function	oxidoreductase activity
L	0046872	molecular_function	metal ion binding
L	0051409	biological_process	response to nitrosative stress
L	0140315	molecular_function	iron ion sequestering activity
L	0140737	cellular_component	encapsulin nanocompartment
M	0001666	biological_process	response to hypoxia
M	0004322	molecular_function	ferroxidase activity
M	0005576	cellular_component	extracellular region
M	0005737	cellular_component	cytoplasm
M	0005829	cellular_component	cytosol
M	0005886	cellular_component	plasma membrane
M	0006826	biological_process	iron ion transport
M	0006879	biological_process	intracellular iron ion homeostasis
M	0006880	biological_process	intracellular sequestering of iron ion
M	0008198	molecular_function	ferrous iron binding
M	0008199	molecular_function	ferric iron binding
M	0009274	cellular_component	peptidoglycan-based cell wall
M	0016491	molecular_function	oxidoreductase activity
M	0046872	molecular_function	metal ion binding
M	0051409	biological_process	response to nitrosative stress
M	0140315	molecular_function	iron ion sequestering activity
M	0140737	cellular_component	encapsulin nanocompartment
N	0001666	biological_process	response to hypoxia
N	0004322	molecular_function	ferroxidase activity
N	0005576	cellular_component	extracellular region
N	0005737	cellular_component	cytoplasm
N	0005829	cellular_component	cytosol
N	0005886	cellular_component	plasma membrane
N	0006826	biological_process	iron ion transport
N	0006879	biological_process	intracellular iron ion homeostasis
N	0006880	biological_process	intracellular sequestering of iron ion
N	0008198	molecular_function	ferrous iron binding
N	0008199	molecular_function	ferric iron binding
N	0009274	cellular_component	peptidoglycan-based cell wall
N	0016491	molecular_function	oxidoreductase activity
N	0046872	molecular_function	metal ion binding
N	0051409	biological_process	response to nitrosative stress
N	0140315	molecular_function	iron ion sequestering activity
N	0140737	cellular_component	encapsulin nanocompartment
O	0001666	biological_process	response to hypoxia
O	0004322	molecular_function	ferroxidase activity
O	0005576	cellular_component	extracellular region
O	0005737	cellular_component	cytoplasm
O	0005829	cellular_component	cytosol
O	0005886	cellular_component	plasma membrane
O	0006826	biological_process	iron ion transport
O	0006879	biological_process	intracellular iron ion homeostasis
O	0006880	biological_process	intracellular sequestering of iron ion
O	0008198	molecular_function	ferrous iron binding
O	0008199	molecular_function	ferric iron binding
O	0009274	cellular_component	peptidoglycan-based cell wall
O	0016491	molecular_function	oxidoreductase activity
O	0046872	molecular_function	metal ion binding
O	0051409	biological_process	response to nitrosative stress
O	0140315	molecular_function	iron ion sequestering activity
O	0140737	cellular_component	encapsulin nanocompartment
P	0001666	biological_process	response to hypoxia
P	0004322	molecular_function	ferroxidase activity
P	0005576	cellular_component	extracellular region
P	0005737	cellular_component	cytoplasm
P	0005829	cellular_component	cytosol
P	0005886	cellular_component	plasma membrane
P	0006826	biological_process	iron ion transport
P	0006879	biological_process	intracellular iron ion homeostasis
P	0006880	biological_process	intracellular sequestering of iron ion
P	0008198	molecular_function	ferrous iron binding
P	0008199	molecular_function	ferric iron binding
P	0009274	cellular_component	peptidoglycan-based cell wall
P	0016491	molecular_function	oxidoreductase activity
P	0046872	molecular_function	metal ion binding
P	0051409	biological_process	response to nitrosative stress
P	0140315	molecular_function	iron ion sequestering activity
P	0140737	cellular_component	encapsulin nanocompartment
Q	0001666	biological_process	response to hypoxia
Q	0004322	molecular_function	ferroxidase activity
Q	0005576	cellular_component	extracellular region
Q	0005737	cellular_component	cytoplasm
Q	0005829	cellular_component	cytosol
Q	0005886	cellular_component	plasma membrane
Q	0006826	biological_process	iron ion transport
Q	0006879	biological_process	intracellular iron ion homeostasis
Q	0006880	biological_process	intracellular sequestering of iron ion
Q	0008198	molecular_function	ferrous iron binding
Q	0008199	molecular_function	ferric iron binding
Q	0009274	cellular_component	peptidoglycan-based cell wall
Q	0016491	molecular_function	oxidoreductase activity
Q	0046872	molecular_function	metal ion binding
Q	0051409	biological_process	response to nitrosative stress
Q	0140315	molecular_function	iron ion sequestering activity
Q	0140737	cellular_component	encapsulin nanocompartment
R	0001666	biological_process	response to hypoxia
R	0004322	molecular_function	ferroxidase activity
R	0005576	cellular_component	extracellular region
R	0005737	cellular_component	cytoplasm
R	0005829	cellular_component	cytosol
R	0005886	cellular_component	plasma membrane
R	0006826	biological_process	iron ion transport
R	0006879	biological_process	intracellular iron ion homeostasis
R	0006880	biological_process	intracellular sequestering of iron ion
R	0008198	molecular_function	ferrous iron binding
R	0008199	molecular_function	ferric iron binding
R	0009274	cellular_component	peptidoglycan-based cell wall
R	0016491	molecular_function	oxidoreductase activity
R	0046872	molecular_function	metal ion binding
R	0051409	biological_process	response to nitrosative stress
R	0140315	molecular_function	iron ion sequestering activity
R	0140737	cellular_component	encapsulin nanocompartment
S	0001666	biological_process	response to hypoxia
S	0004322	molecular_function	ferroxidase activity
S	0005576	cellular_component	extracellular region
S	0005737	cellular_component	cytoplasm
S	0005829	cellular_component	cytosol
S	0005886	cellular_component	plasma membrane
S	0006826	biological_process	iron ion transport
S	0006879	biological_process	intracellular iron ion homeostasis
S	0006880	biological_process	intracellular sequestering of iron ion
S	0008198	molecular_function	ferrous iron binding
S	0008199	molecular_function	ferric iron binding
S	0009274	cellular_component	peptidoglycan-based cell wall
S	0016491	molecular_function	oxidoreductase activity
S	0046872	molecular_function	metal ion binding
S	0051409	biological_process	response to nitrosative stress
S	0140315	molecular_function	iron ion sequestering activity
S	0140737	cellular_component	encapsulin nanocompartment
T	0001666	biological_process	response to hypoxia
T	0004322	molecular_function	ferroxidase activity
T	0005576	cellular_component	extracellular region
T	0005737	cellular_component	cytoplasm
T	0005829	cellular_component	cytosol
T	0005886	cellular_component	plasma membrane
T	0006826	biological_process	iron ion transport
T	0006879	biological_process	intracellular iron ion homeostasis
T	0006880	biological_process	intracellular sequestering of iron ion
T	0008198	molecular_function	ferrous iron binding
T	0008199	molecular_function	ferric iron binding
T	0009274	cellular_component	peptidoglycan-based cell wall
T	0016491	molecular_function	oxidoreductase activity
T	0046872	molecular_function	metal ion binding
T	0051409	biological_process	response to nitrosative stress
T	0140315	molecular_function	iron ion sequestering activity
T	0140737	cellular_component	encapsulin nanocompartment
V	0001666	biological_process	response to hypoxia
V	0004322	molecular_function	ferroxidase activity
V	0005576	cellular_component	extracellular region
V	0005737	cellular_component	cytoplasm
V	0005829	cellular_component	cytosol
V	0005886	cellular_component	plasma membrane
V	0006826	biological_process	iron ion transport
V	0006879	biological_process	intracellular iron ion homeostasis
V	0006880	biological_process	intracellular sequestering of iron ion
V	0008198	molecular_function	ferrous iron binding
V	0008199	molecular_function	ferric iron binding
V	0009274	cellular_component	peptidoglycan-based cell wall
V	0016491	molecular_function	oxidoreductase activity
V	0046872	molecular_function	metal ion binding
V	0051409	biological_process	response to nitrosative stress
V	0140315	molecular_function	iron ion sequestering activity
V	0140737	cellular_component	encapsulin nanocompartment
W	0001666	biological_process	response to hypoxia
W	0004322	molecular_function	ferroxidase activity
W	0005576	cellular_component	extracellular region
W	0005737	cellular_component	cytoplasm
W	0005829	cellular_component	cytosol
W	0005886	cellular_component	plasma membrane
W	0006826	biological_process	iron ion transport
W	0006879	biological_process	intracellular iron ion homeostasis
W	0006880	biological_process	intracellular sequestering of iron ion
W	0008198	molecular_function	ferrous iron binding
W	0008199	molecular_function	ferric iron binding
W	0009274	cellular_component	peptidoglycan-based cell wall
W	0016491	molecular_function	oxidoreductase activity
W	0046872	molecular_function	metal ion binding
W	0051409	biological_process	response to nitrosative stress
W	0140315	molecular_function	iron ion sequestering activity
W	0140737	cellular_component	encapsulin nanocompartment
X	0001666	biological_process	response to hypoxia
X	0004322	molecular_function	ferroxidase activity
X	0005576	cellular_component	extracellular region
X	0005737	cellular_component	cytoplasm
X	0005829	cellular_component	cytosol
X	0005886	cellular_component	plasma membrane
X	0006826	biological_process	iron ion transport
X	0006879	biological_process	intracellular iron ion homeostasis
X	0006880	biological_process	intracellular sequestering of iron ion
X	0008198	molecular_function	ferrous iron binding
X	0008199	molecular_function	ferric iron binding
X	0009274	cellular_component	peptidoglycan-based cell wall
X	0016491	molecular_function	oxidoreductase activity
X	0046872	molecular_function	metal ion binding
X	0051409	biological_process	response to nitrosative stress
X	0140315	molecular_function	iron ion sequestering activity
X	0140737	cellular_component	encapsulin nanocompartment
Y	0001666	biological_process	response to hypoxia
Y	0004322	molecular_function	ferroxidase activity
Y	0005576	cellular_component	extracellular region
Y	0005737	cellular_component	cytoplasm
Y	0005829	cellular_component	cytosol
Y	0005886	cellular_component	plasma membrane
Y	0006826	biological_process	iron ion transport
Y	0006879	biological_process	intracellular iron ion homeostasis
Y	0006880	biological_process	intracellular sequestering of iron ion
Y	0008198	molecular_function	ferrous iron binding
Y	0008199	molecular_function	ferric iron binding
Y	0009274	cellular_component	peptidoglycan-based cell wall
Y	0016491	molecular_function	oxidoreductase activity
Y	0046872	molecular_function	metal ion binding
Y	0051409	biological_process	response to nitrosative stress
Y	0140315	molecular_function	iron ion sequestering activity
Y	0140737	cellular_component	encapsulin nanocompartment

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	120
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00085

Chain	Residue	Details
A	GLU22
B	GLN132
T	GLN132
V	GLU22
V	GLU55
V	HIS58
V	GLU99
V	GLN132
W	GLU22
W	GLU55
W	HIS58
W	GLU99
C	GLU22
W	GLN132
X	GLU22
X	GLU55
X	HIS58
X	GLU99
X	GLN132
Y	GLU22
Y	GLU55
Y	HIS58
Y	GLU99
C	GLU55
Y	GLN132
C	HIS58
C	GLU99
C	GLN132
D	GLU22
D	GLU55
D	HIS58
D	GLU99
A	GLU55
D	GLN132
E	GLU22
E	GLU55
E	HIS58
E	GLU99
E	GLN132
F	GLU22
F	GLU55
F	HIS58
F	GLU99
A	HIS58
F	GLN132
G	GLU22
G	GLU55
G	HIS58
G	GLU99
G	GLN132
H	GLU22
H	GLU55
H	HIS58
H	GLU99
A	GLU99
H	GLN132
I	GLU22
I	GLU55
I	HIS58
I	GLU99
I	GLN132
J	GLU22
J	GLU55
J	HIS58
J	GLU99
A	GLN132
J	GLN132
K	GLU22
K	GLU55
K	HIS58
K	GLU99
K	GLN132
L	GLU22
L	GLU55
L	HIS58
L	GLU99
B	GLU22
L	GLN132
M	GLU22
M	GLU55
M	HIS58
M	GLU99
M	GLN132
N	GLU22
N	GLU55
N	HIS58
N	GLU99
B	GLU55
N	GLN132
O	GLU22
O	GLU55
O	HIS58
O	GLU99
O	GLN132
P	GLU22
P	GLU55
P	HIS58
P	GLU99
B	HIS58
P	GLN132
Q	GLU22
Q	GLU55
Q	HIS58
Q	GLU99
Q	GLN132
R	GLU22
R	GLU55
R	HIS58
R	GLU99
B	GLU99
R	GLN132
S	GLU22
S	GLU55
S	HIS58
S	GLU99
S	GLN132
T	GLU22
T	GLU55
T	HIS58
T	GLU99

---