8A97

ROOM TEMPERATURE CRYSTAL STRUCTURE OF THE COFACTOR-DEVOID 1-H-3-HYDROXY-4- OXOQUINALDINE 2,4-DIOXYGENASE (HOD) UNDER XENON PRESSURE (30 bar)

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
AAA	0003824	molecular_function	catalytic activity
AAA	0009056	biological_process	catabolic process
AAA	0016702	molecular_function	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
AAA	0050586	molecular_function	3-hydroxy-2-methylquinolin-4-one 2,4-dioxygenase activity
AAA	0051213	molecular_function	dioxygenase activity
BBB	0003824	molecular_function	catalytic activity
BBB	0009056	biological_process	catabolic process
BBB	0016702	molecular_function	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
BBB	0050586	molecular_function	3-hydroxy-2-methylquinolin-4-one 2,4-dioxygenase activity
BBB	0051213	molecular_function	dioxygenase activity
CCC	0003824	molecular_function	catalytic activity
CCC	0009056	biological_process	catabolic process
CCC	0016702	molecular_function	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
CCC	0050586	molecular_function	3-hydroxy-2-methylquinolin-4-one 2,4-dioxygenase activity
CCC	0051213	molecular_function	dioxygenase activity
DDD	0003824	molecular_function	catalytic activity
DDD	0009056	biological_process	catabolic process
DDD	0016702	molecular_function	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
DDD	0050586	molecular_function	3-hydroxy-2-methylquinolin-4-one 2,4-dioxygenase activity
DDD	0051213	molecular_function	dioxygenase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Proton donor/acceptor => ECO:0000269|PubMed:16187153

Chain	Residue	Details
AAA	HIS251
BBB	HIS251
CCC	HIS251
DDD	HIS251

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site_id	SWS_FT_FI2
Number of Residues	12
Details	BINDING:

Chain	Residue	Details
AAA	TRP36
DDD	TRP36
DDD	HIS100
DDD	TRP160
AAA	HIS100
AAA	TRP160
BBB	TRP36
BBB	HIS100
BBB	TRP160
CCC	TRP36
CCC	HIS100
CCC	TRP160

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site_id	SWS_FT_FI3
Number of Residues	4
Details	SITE: Increases basicity of active site His => ECO:0000250|UniProtKB:B1MFK2

Chain	Residue	Details
AAA	ASP126
BBB	ASP126
CCC	ASP126
DDD	ASP126

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