Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

8A8E

PPSA C terminal octahedral structure

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003824	molecular_function	catalytic activity
A	0005524	molecular_function	ATP binding
A	0006090	biological_process	pyruvate metabolic process
A	0006094	biological_process	gluconeogenesis
A	0008986	molecular_function	pyruvate, water dikinase activity
A	0016301	molecular_function	kinase activity
A	0016310	biological_process	phosphorylation
A	0016740	molecular_function	transferase activity
A	0016772	molecular_function	transferase activity, transferring phosphorus-containing groups
A	0046872	molecular_function	metal ion binding
B	0000166	molecular_function	nucleotide binding
B	0003824	molecular_function	catalytic activity
B	0005524	molecular_function	ATP binding
B	0006090	biological_process	pyruvate metabolic process
B	0006094	biological_process	gluconeogenesis
B	0008986	molecular_function	pyruvate, water dikinase activity
B	0016301	molecular_function	kinase activity
B	0016310	biological_process	phosphorylation
B	0016740	molecular_function	transferase activity
B	0016772	molecular_function	transferase activity, transferring phosphorus-containing groups
B	0046872	molecular_function	metal ion binding
C	0000166	molecular_function	nucleotide binding
C	0003824	molecular_function	catalytic activity
C	0005524	molecular_function	ATP binding
C	0006090	biological_process	pyruvate metabolic process
C	0006094	biological_process	gluconeogenesis
C	0008986	molecular_function	pyruvate, water dikinase activity
C	0016301	molecular_function	kinase activity
C	0016310	biological_process	phosphorylation
C	0016740	molecular_function	transferase activity
C	0016772	molecular_function	transferase activity, transferring phosphorus-containing groups
C	0046872	molecular_function	metal ion binding
D	0000166	molecular_function	nucleotide binding
D	0003824	molecular_function	catalytic activity
D	0005524	molecular_function	ATP binding
D	0006090	biological_process	pyruvate metabolic process
D	0006094	biological_process	gluconeogenesis
D	0008986	molecular_function	pyruvate, water dikinase activity
D	0016301	molecular_function	kinase activity
D	0016310	biological_process	phosphorylation
D	0016740	molecular_function	transferase activity
D	0016772	molecular_function	transferase activity, transferring phosphorus-containing groups
D	0046872	molecular_function	metal ion binding
E	0000166	molecular_function	nucleotide binding
E	0003824	molecular_function	catalytic activity
E	0005524	molecular_function	ATP binding
E	0006090	biological_process	pyruvate metabolic process
E	0006094	biological_process	gluconeogenesis
E	0008986	molecular_function	pyruvate, water dikinase activity
E	0016301	molecular_function	kinase activity
E	0016310	biological_process	phosphorylation
E	0016740	molecular_function	transferase activity
E	0016772	molecular_function	transferase activity, transferring phosphorus-containing groups
E	0046872	molecular_function	metal ion binding
F	0000166	molecular_function	nucleotide binding
F	0003824	molecular_function	catalytic activity
F	0005524	molecular_function	ATP binding
F	0006090	biological_process	pyruvate metabolic process
F	0006094	biological_process	gluconeogenesis
F	0008986	molecular_function	pyruvate, water dikinase activity
F	0016301	molecular_function	kinase activity
F	0016310	biological_process	phosphorylation
F	0016740	molecular_function	transferase activity
F	0016772	molecular_function	transferase activity, transferring phosphorus-containing groups
F	0046872	molecular_function	metal ion binding
G	0000166	molecular_function	nucleotide binding
G	0003824	molecular_function	catalytic activity
G	0005524	molecular_function	ATP binding
G	0006090	biological_process	pyruvate metabolic process
G	0006094	biological_process	gluconeogenesis
G	0008986	molecular_function	pyruvate, water dikinase activity
G	0016301	molecular_function	kinase activity
G	0016310	biological_process	phosphorylation
G	0016740	molecular_function	transferase activity
G	0016772	molecular_function	transferase activity, transferring phosphorus-containing groups
G	0046872	molecular_function	metal ion binding
H	0000166	molecular_function	nucleotide binding
H	0003824	molecular_function	catalytic activity
H	0005524	molecular_function	ATP binding
H	0006090	biological_process	pyruvate metabolic process
H	0006094	biological_process	gluconeogenesis
H	0008986	molecular_function	pyruvate, water dikinase activity
H	0016301	molecular_function	kinase activity
H	0016310	biological_process	phosphorylation
H	0016740	molecular_function	transferase activity
H	0016772	molecular_function	transferase activity, transferring phosphorus-containing groups
H	0046872	molecular_function	metal ion binding
I	0000166	molecular_function	nucleotide binding
I	0003824	molecular_function	catalytic activity
I	0005524	molecular_function	ATP binding
I	0006090	biological_process	pyruvate metabolic process
I	0006094	biological_process	gluconeogenesis
I	0008986	molecular_function	pyruvate, water dikinase activity
I	0016301	molecular_function	kinase activity
I	0016310	biological_process	phosphorylation
I	0016740	molecular_function	transferase activity
I	0016772	molecular_function	transferase activity, transferring phosphorus-containing groups
I	0046872	molecular_function	metal ion binding
J	0000166	molecular_function	nucleotide binding
J	0003824	molecular_function	catalytic activity
J	0005524	molecular_function	ATP binding
J	0006090	biological_process	pyruvate metabolic process
J	0006094	biological_process	gluconeogenesis
J	0008986	molecular_function	pyruvate, water dikinase activity
J	0016301	molecular_function	kinase activity
J	0016310	biological_process	phosphorylation
J	0016740	molecular_function	transferase activity
J	0016772	molecular_function	transferase activity, transferring phosphorus-containing groups
J	0046872	molecular_function	metal ion binding
K	0000166	molecular_function	nucleotide binding
K	0003824	molecular_function	catalytic activity
K	0005524	molecular_function	ATP binding
K	0006090	biological_process	pyruvate metabolic process
K	0006094	biological_process	gluconeogenesis
K	0008986	molecular_function	pyruvate, water dikinase activity
K	0016301	molecular_function	kinase activity
K	0016310	biological_process	phosphorylation
K	0016740	molecular_function	transferase activity
K	0016772	molecular_function	transferase activity, transferring phosphorus-containing groups
K	0046872	molecular_function	metal ion binding
L	0000166	molecular_function	nucleotide binding
L	0003824	molecular_function	catalytic activity
L	0005524	molecular_function	ATP binding
L	0006090	biological_process	pyruvate metabolic process
L	0006094	biological_process	gluconeogenesis
L	0008986	molecular_function	pyruvate, water dikinase activity
L	0016301	molecular_function	kinase activity
L	0016310	biological_process	phosphorylation
L	0016740	molecular_function	transferase activity
L	0016772	molecular_function	transferase activity, transferring phosphorus-containing groups
L	0046872	molecular_function	metal ion binding
M	0000166	molecular_function	nucleotide binding
M	0003824	molecular_function	catalytic activity
M	0005524	molecular_function	ATP binding
M	0006090	biological_process	pyruvate metabolic process
M	0006094	biological_process	gluconeogenesis
M	0008986	molecular_function	pyruvate, water dikinase activity
M	0016301	molecular_function	kinase activity
M	0016310	biological_process	phosphorylation
M	0016740	molecular_function	transferase activity
M	0016772	molecular_function	transferase activity, transferring phosphorus-containing groups
M	0046872	molecular_function	metal ion binding
N	0000166	molecular_function	nucleotide binding
N	0003824	molecular_function	catalytic activity
N	0005524	molecular_function	ATP binding
N	0006090	biological_process	pyruvate metabolic process
N	0006094	biological_process	gluconeogenesis
N	0008986	molecular_function	pyruvate, water dikinase activity
N	0016301	molecular_function	kinase activity
N	0016310	biological_process	phosphorylation
N	0016740	molecular_function	transferase activity
N	0016772	molecular_function	transferase activity, transferring phosphorus-containing groups
N	0046872	molecular_function	metal ion binding
O	0000166	molecular_function	nucleotide binding
O	0003824	molecular_function	catalytic activity
O	0005524	molecular_function	ATP binding
O	0006090	biological_process	pyruvate metabolic process
O	0006094	biological_process	gluconeogenesis
O	0008986	molecular_function	pyruvate, water dikinase activity
O	0016301	molecular_function	kinase activity
O	0016310	biological_process	phosphorylation
O	0016740	molecular_function	transferase activity
O	0016772	molecular_function	transferase activity, transferring phosphorus-containing groups
O	0046872	molecular_function	metal ion binding
P	0000166	molecular_function	nucleotide binding
P	0003824	molecular_function	catalytic activity
P	0005524	molecular_function	ATP binding
P	0006090	biological_process	pyruvate metabolic process
P	0006094	biological_process	gluconeogenesis
P	0008986	molecular_function	pyruvate, water dikinase activity
P	0016301	molecular_function	kinase activity
P	0016310	biological_process	phosphorylation
P	0016740	molecular_function	transferase activity
P	0016772	molecular_function	transferase activity, transferring phosphorus-containing groups
P	0046872	molecular_function	metal ion binding
Q	0000166	molecular_function	nucleotide binding
Q	0003824	molecular_function	catalytic activity
Q	0005524	molecular_function	ATP binding
Q	0006090	biological_process	pyruvate metabolic process
Q	0006094	biological_process	gluconeogenesis
Q	0008986	molecular_function	pyruvate, water dikinase activity
Q	0016301	molecular_function	kinase activity
Q	0016310	biological_process	phosphorylation
Q	0016740	molecular_function	transferase activity
Q	0016772	molecular_function	transferase activity, transferring phosphorus-containing groups
Q	0046872	molecular_function	metal ion binding
R	0000166	molecular_function	nucleotide binding
R	0003824	molecular_function	catalytic activity
R	0005524	molecular_function	ATP binding
R	0006090	biological_process	pyruvate metabolic process
R	0006094	biological_process	gluconeogenesis
R	0008986	molecular_function	pyruvate, water dikinase activity
R	0016301	molecular_function	kinase activity
R	0016310	biological_process	phosphorylation
R	0016740	molecular_function	transferase activity
R	0016772	molecular_function	transferase activity, transferring phosphorus-containing groups
R	0046872	molecular_function	metal ion binding
S	0000166	molecular_function	nucleotide binding
S	0003824	molecular_function	catalytic activity
S	0005524	molecular_function	ATP binding
S	0006090	biological_process	pyruvate metabolic process
S	0006094	biological_process	gluconeogenesis
S	0008986	molecular_function	pyruvate, water dikinase activity
S	0016301	molecular_function	kinase activity
S	0016310	biological_process	phosphorylation
S	0016740	molecular_function	transferase activity
S	0016772	molecular_function	transferase activity, transferring phosphorus-containing groups
S	0046872	molecular_function	metal ion binding
T	0000166	molecular_function	nucleotide binding
T	0003824	molecular_function	catalytic activity
T	0005524	molecular_function	ATP binding
T	0006090	biological_process	pyruvate metabolic process
T	0006094	biological_process	gluconeogenesis
T	0008986	molecular_function	pyruvate, water dikinase activity
T	0016301	molecular_function	kinase activity
T	0016310	biological_process	phosphorylation
T	0016740	molecular_function	transferase activity
T	0016772	molecular_function	transferase activity, transferring phosphorus-containing groups
T	0046872	molecular_function	metal ion binding
U	0000166	molecular_function	nucleotide binding
U	0003824	molecular_function	catalytic activity
U	0005524	molecular_function	ATP binding
U	0006090	biological_process	pyruvate metabolic process
U	0006094	biological_process	gluconeogenesis
U	0008986	molecular_function	pyruvate, water dikinase activity
U	0016301	molecular_function	kinase activity
U	0016310	biological_process	phosphorylation
U	0016740	molecular_function	transferase activity
U	0016772	molecular_function	transferase activity, transferring phosphorus-containing groups
U	0046872	molecular_function	metal ion binding
V	0000166	molecular_function	nucleotide binding
V	0003824	molecular_function	catalytic activity
V	0005524	molecular_function	ATP binding
V	0006090	biological_process	pyruvate metabolic process
V	0006094	biological_process	gluconeogenesis
V	0008986	molecular_function	pyruvate, water dikinase activity
V	0016301	molecular_function	kinase activity
V	0016310	biological_process	phosphorylation
V	0016740	molecular_function	transferase activity
V	0016772	molecular_function	transferase activity, transferring phosphorus-containing groups
V	0046872	molecular_function	metal ion binding
W	0000166	molecular_function	nucleotide binding
W	0003824	molecular_function	catalytic activity
W	0005524	molecular_function	ATP binding
W	0006090	biological_process	pyruvate metabolic process
W	0006094	biological_process	gluconeogenesis
W	0008986	molecular_function	pyruvate, water dikinase activity
W	0016301	molecular_function	kinase activity
W	0016310	biological_process	phosphorylation
W	0016740	molecular_function	transferase activity
W	0016772	molecular_function	transferase activity, transferring phosphorus-containing groups
W	0046872	molecular_function	metal ion binding
X	0000166	molecular_function	nucleotide binding
X	0003824	molecular_function	catalytic activity
X	0005524	molecular_function	ATP binding
X	0006090	biological_process	pyruvate metabolic process
X	0006094	biological_process	gluconeogenesis
X	0008986	molecular_function	pyruvate, water dikinase activity
X	0016301	molecular_function	kinase activity
X	0016310	biological_process	phosphorylation
X	0016740	molecular_function	transferase activity
X	0016772	molecular_function	transferase activity, transferring phosphorus-containing groups
X	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS00370
Number of Residues	12
Details	PEP_ENZYMES_PHOS_SITE PEP-utilizing enzymes phosphorylation site signature. GGrTsHAAIVSR

Chain	Residue	Details
A	GLY-68-ARG-57

site_id	PS00742
Number of Residues	19
Details	PEP_ENZYMES_2 PEP-utilizing enzymes signature 2. DfVSFGTNDLtQYTLAidR

Chain	Residue	Details
A	ASP196-ARG214

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	24
Details	ACT_SITE: Tele-phosphohistidine intermediate => ECO:0000250

Chain	Residue	Details
A	HIS-63
J	HIS-63
K	HIS-63
L	HIS-63
M	HIS-63
N	HIS-63
O	HIS-63
P	HIS-63
Q	HIS-63
R	HIS-63
S	HIS-63
B	HIS-63
T	HIS-63
U	HIS-63
V	HIS-63
W	HIS-63
X	HIS-63
C	HIS-63
D	HIS-63
E	HIS-63
F	HIS-63
G	HIS-63
H	HIS-63
I	HIS-63

site_id	SWS_FT_FI2
Number of Residues	24
Details	ACT_SITE: Proton donor => ECO:0000250

Chain	Residue	Details
A	CYS251
J	CYS251
K	CYS251
L	CYS251
M	CYS251
N	CYS251
O	CYS251
P	CYS251
Q	CYS251
R	CYS251
S	CYS251
B	CYS251
T	CYS251
U	CYS251
V	CYS251
W	CYS251
X	CYS251
C	CYS251
D	CYS251
E	CYS251
F	CYS251
G	CYS251
H	CYS251
I	CYS251

site_id	SWS_FT_FI3
Number of Residues	168
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	ARG35
B	GLU179
O	ARG82
O	GLU179
O	GLY201
O	THR202
O	ASN203
O	ASP204
P	ARG35
P	ARG82
P	GLU179
P	GLY201
B	GLY201
P	THR202
P	ASN203
P	ASP204
Q	ARG35
Q	ARG82
Q	GLU179
Q	GLY201
Q	THR202
Q	ASN203
Q	ASP204
B	THR202
R	ARG35
R	ARG82
R	GLU179
R	GLY201
R	THR202
R	ASN203
R	ASP204
S	ARG35
S	ARG82
S	GLU179
B	ASN203
S	GLY201
S	THR202
S	ASN203
S	ASP204
T	ARG35
T	ARG82
T	GLU179
T	GLY201
T	THR202
T	ASN203
B	ASP204
T	ASP204
U	ARG35
U	ARG82
U	GLU179
U	GLY201
U	THR202
U	ASN203
U	ASP204
V	ARG35
V	ARG82
C	ARG35
V	GLU179
V	GLY201
V	THR202
V	ASN203
V	ASP204
W	ARG35
W	ARG82
W	GLU179
W	GLY201
W	THR202
C	ARG82
W	ASN203
W	ASP204
X	ARG35
X	ARG82
X	GLU179
X	GLY201
X	THR202
X	ASN203
X	ASP204
C	GLU179
C	GLY201
C	THR202
A	ARG82
C	ASN203
C	ASP204
D	ARG35
D	ARG82
D	GLU179
D	GLY201
D	THR202
D	ASN203
D	ASP204
E	ARG35
A	GLU179
E	ARG82
E	GLU179
E	GLY201
E	THR202
E	ASN203
E	ASP204
F	ARG35
F	ARG82
F	GLU179
F	GLY201
A	GLY201
F	THR202
F	ASN203
F	ASP204
G	ARG35
G	ARG82
G	GLU179
G	GLY201
G	THR202
G	ASN203
G	ASP204
A	THR202
H	ARG35
H	ARG82
H	GLU179
H	GLY201
H	THR202
H	ASN203
H	ASP204
I	ARG35
I	ARG82
I	GLU179
A	ASN203
I	GLY201
I	THR202
I	ASN203
I	ASP204
J	ARG35
J	ARG82
J	GLU179
J	GLY201
J	THR202
J	ASN203
A	ASP204
J	ASP204
K	ARG35
K	ARG82
K	GLU179
K	GLY201
K	THR202
K	ASN203
K	ASP204
L	ARG35
L	ARG82
B	ARG35
L	GLU179
L	GLY201
L	THR202
L	ASN203
L	ASP204
M	ARG35
M	ARG82
M	GLU179
M	GLY201
M	THR202
B	ARG82
M	ASN203
M	ASP204
N	ARG35
N	ARG82
N	GLU179
N	GLY201
N	THR202
N	ASN203
N	ASP204
O	ARG35

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)