8A8C
T5 phage receptor-binding protein pb5 bound to ferrichrome transporter FhuA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0006811 | biological_process | monoatomic ion transport |
| A | 0006826 | biological_process | iron ion transport |
| A | 0006879 | biological_process | intracellular iron ion homeostasis |
| A | 0009279 | cellular_component | cell outer membrane |
| A | 0015343 | molecular_function | siderophore-iron transmembrane transporter activity |
| A | 0015344 | molecular_function | siderophore uptake transmembrane transporter activity |
| A | 0015643 | molecular_function | toxic substance binding |
| A | 0015891 | biological_process | siderophore transport |
| A | 0016020 | cellular_component | membrane |
| A | 0019904 | molecular_function | protein domain specific binding |
| A | 0033214 | biological_process | siderophore-iron import into cell |
| A | 0038023 | molecular_function | signaling receptor activity |
| A | 0044718 | biological_process | siderophore transmembrane transport |
| A | 0046790 | molecular_function | virion binding |
| A | 1902495 | cellular_component | transmembrane transporter complex |
| B | 0019062 | biological_process | virion attachment to host cell |
| B | 0044423 | cellular_component | virion component |
| B | 0046718 | biological_process | symbiont entry into host cell |
| B | 0046813 | biological_process | receptor-mediated virion attachment to host cell |
| B | 0098015 | cellular_component | virus tail |
| B | 0098670 | biological_process | entry receptor-mediated virion attachment to host cell |
Functional Information from PROSITE/UniProt
| site_id | PS01156 |
| Number of Residues | 18 |
| Details | TONB_DEPENDENT_REC_2 TonB-dependent receptor (TBDR) proteins signature 2. GcfwGaERqVvATAtFrF |
| Chain | Residue | Details |
| A | GLY697-PHE714 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 177 |
| Details | Transmembrane: {"description":"Beta stranded"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 289 |
| Details | Topological domain: {"description":"Extracellular"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 46 |
| Details | Topological domain: {"description":"Periplasmic"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 112 |
| Details | Domain: {"description":"TBDR plug","evidences":[{"source":"PROSITE-ProRule","id":"PRU01360","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 555 |
| Details | Domain: {"description":"TBDR beta-barrel","evidences":[{"source":"PROSITE-ProRule","id":"PRU01360","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 17 |
| Details | Motif: {"description":"TonB C-terminal box"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10850805","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"9856937","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"9865695","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"9856937","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 1 |
| Details | Site: {"description":"Interaction with phage T5 RBP-pb5","evidences":[{"source":"PubMed","id":"36779755","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 9 |
| Details | Region: {"description":"Interaction with host FhuA","evidences":[{"source":"PubMed","id":"36779755","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 1 |
| Details | Site: {"description":"Interaction with host FhuA receptor","evidences":[{"source":"PubMed","id":"36779755","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
