8A6T

Cryo-EM structure of the electron bifurcating Fe-Fe hydrogenase HydABC complex from Thermoanaerobacter kivui in the reduced state

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005506	molecular_function	iron ion binding
A	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
A	0008901	molecular_function	ferredoxin hydrogenase activity
A	0016020	cellular_component	membrane
A	0016491	molecular_function	oxidoreductase activity
A	0042773	biological_process	ATP synthesis coupled electron transport
A	0046872	molecular_function	metal ion binding
A	0050583	molecular_function	hydrogen dehydrogenase (NADP+) activity
A	0051536	molecular_function	iron-sulfur cluster binding
A	0051539	molecular_function	4 iron, 4 sulfur cluster binding
A	0055085	biological_process	transmembrane transport
B	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
B	0010181	molecular_function	FMN binding
B	0016491	molecular_function	oxidoreductase activity
B	0046872	molecular_function	metal ion binding
B	0050583	molecular_function	hydrogen dehydrogenase (NADP+) activity
B	0051539	molecular_function	4 iron, 4 sulfur cluster binding
B	0055085	biological_process	transmembrane transport
C	0016491	molecular_function	oxidoreductase activity
C	0046872	molecular_function	metal ion binding
C	0050583	molecular_function	hydrogen dehydrogenase (NADP+) activity
C	0051537	molecular_function	2 iron, 2 sulfur cluster binding
D	0005506	molecular_function	iron ion binding
D	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
D	0008901	molecular_function	ferredoxin hydrogenase activity
D	0016020	cellular_component	membrane
D	0016491	molecular_function	oxidoreductase activity
D	0042773	biological_process	ATP synthesis coupled electron transport
D	0046872	molecular_function	metal ion binding
D	0050583	molecular_function	hydrogen dehydrogenase (NADP+) activity
D	0051536	molecular_function	iron-sulfur cluster binding
D	0051539	molecular_function	4 iron, 4 sulfur cluster binding
D	0055085	biological_process	transmembrane transport
E	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
E	0010181	molecular_function	FMN binding
E	0016491	molecular_function	oxidoreductase activity
E	0046872	molecular_function	metal ion binding
E	0050583	molecular_function	hydrogen dehydrogenase (NADP+) activity
E	0051539	molecular_function	4 iron, 4 sulfur cluster binding
E	0055085	biological_process	transmembrane transport
F	0016491	molecular_function	oxidoreductase activity
F	0046872	molecular_function	metal ion binding
F	0050583	molecular_function	hydrogen dehydrogenase (NADP+) activity
F	0051537	molecular_function	2 iron, 2 sulfur cluster binding

Functional Information from PROSITE/UniProt

site_id	PS00198
Number of Residues	12
Details	4FE4S_FER_1 4Fe-4S ferredoxin-type iron-sulfur binding region signature. CiLCGkCVrICE

Chain	Residue	Details
A	CYS146-GLU157
A	CYS189-PRO200
B	CYS582-PRO593
B	CYS612-PRO623

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site_id	PS00641
Number of Residues	18
Details	COMPLEX1_75K_1 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. PglCDdndlkpfGaCRlC

Chain	Residue	Details
A	PRO33-CYS50

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site_id	PS00645
Number of Residues	12
Details	COMPLEX1_51K_2 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. ESCGkCiPCReG

Chain	Residue	Details
B	GLU486-GLY497

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site_id	PS01099
Number of Residues	19
Details	COMPLEX1_24K Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. DlkFTlervgCLGaCglAP

Chain	Residue	Details
C	ASP118-PRO136

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