8A3Y

Structure of mammalian Pol II-DSIF-SPT6-PAF1-TFIIS-hexasome elongation complex

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000428	cellular_component	DNA-directed RNA polymerase complex
A	0001054	molecular_function	RNA polymerase I activity
A	0001055	molecular_function	RNA polymerase II activity
A	0001056	molecular_function	RNA polymerase III activity
A	0001057	molecular_function	RNA polymerase IV activity
A	0001058	molecular_function	RNA polymerase V activity
A	0001059	biological_process	transcription by RNA polymerase IV
A	0001060	biological_process	transcription by RNA polymerase V
A	0001065	molecular_function	mitochondrial single subunit type RNA polymerase activity
A	0001066	molecular_function	plastid single subunit type RNA polymerase activity
A	0003677	molecular_function	DNA binding
A	0005634	cellular_component	nucleus
A	0006360	biological_process	transcription by RNA polymerase I
A	0006383	biological_process	transcription by RNA polymerase III
A	0006390	biological_process	mitochondrial transcription
A	0016779	molecular_function	nucleotidyltransferase activity
A	0031981	cellular_component	nuclear lumen
A	0042793	biological_process	plastid transcription
A	0046872	molecular_function	metal ion binding
B	0000428	cellular_component	DNA-directed RNA polymerase complex
B	0000781	cellular_component	chromosome, telomeric region
B	0001054	molecular_function	RNA polymerase I activity
B	0001055	molecular_function	RNA polymerase II activity
B	0001056	molecular_function	RNA polymerase III activity
B	0001057	molecular_function	RNA polymerase IV activity
B	0001058	molecular_function	RNA polymerase V activity
B	0001059	biological_process	transcription by RNA polymerase IV
B	0001060	biological_process	transcription by RNA polymerase V
B	0001065	molecular_function	mitochondrial single subunit type RNA polymerase activity
B	0001066	molecular_function	plastid single subunit type RNA polymerase activity
B	0001172	biological_process	RNA-templated transcription
B	0003682	molecular_function	chromatin binding
B	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
B	0003968	molecular_function	RNA-dependent RNA polymerase activity
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005665	cellular_component	RNA polymerase II, core complex
B	0006360	biological_process	transcription by RNA polymerase I
B	0006366	biological_process	transcription by RNA polymerase II
B	0006383	biological_process	transcription by RNA polymerase III
B	0006390	biological_process	mitochondrial transcription
B	0016779	molecular_function	nucleotidyltransferase activity
B	0034062	molecular_function	5'-3' RNA polymerase activity
B	0042793	biological_process	plastid transcription
B	0046872	molecular_function	metal ion binding
C	0000428	cellular_component	DNA-directed RNA polymerase complex
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005665	cellular_component	RNA polymerase II, core complex
C	0005829	cellular_component	cytosol
C	0006366	biological_process	transcription by RNA polymerase II
E	0001054	molecular_function	RNA polymerase I activity
E	0001055	molecular_function	RNA polymerase II activity
E	0001056	molecular_function	RNA polymerase III activity
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005665	cellular_component	RNA polymerase II, core complex
E	0005666	cellular_component	RNA polymerase III complex
E	0005736	cellular_component	RNA polymerase I complex
E	0006362	biological_process	transcription elongation by RNA polymerase I
E	0006366	biological_process	transcription by RNA polymerase II
E	0042797	biological_process	tRNA transcription by RNA polymerase III
F	0000428	cellular_component	DNA-directed RNA polymerase complex
F	0001650	cellular_component	fibrillar center
F	0005634	cellular_component	nucleus
F	0005654	cellular_component	nucleoplasm
F	0005665	cellular_component	RNA polymerase II, core complex
F	0005666	cellular_component	RNA polymerase III complex
F	0005736	cellular_component	RNA polymerase I complex
F	0006366	biological_process	transcription by RNA polymerase II
G	0000428	cellular_component	DNA-directed RNA polymerase complex
G	0005634	cellular_component	nucleus
G	0006352	biological_process	DNA-templated transcription initiation
H	0000428	cellular_component	DNA-directed RNA polymerase complex
H	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
H	0005634	cellular_component	nucleus
H	0005654	cellular_component	nucleoplasm
H	0005665	cellular_component	RNA polymerase II, core complex
H	0006351	biological_process	DNA-templated transcription
I	0000428	cellular_component	DNA-directed RNA polymerase complex
I	0001193	biological_process	maintenance of transcriptional fidelity during transcription elongation by RNA polymerase II
I	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
I	0005634	cellular_component	nucleus
I	0005654	cellular_component	nucleoplasm
I	0005665	cellular_component	RNA polymerase II, core complex
I	0005730	cellular_component	nucleolus
I	0006283	biological_process	transcription-coupled nucleotide-excision repair
I	0006366	biological_process	transcription by RNA polymerase II
I	0006367	biological_process	transcription initiation at RNA polymerase II promoter
I	0046872	molecular_function	metal ion binding
J	0000428	cellular_component	DNA-directed RNA polymerase complex
J	0046872	molecular_function	metal ion binding
K	0000428	cellular_component	DNA-directed RNA polymerase complex
K	0005634	cellular_component	nucleus
K	0005665	cellular_component	RNA polymerase II, core complex
L	0005634	cellular_component	nucleus
L	0046872	molecular_function	metal ion binding
Q	0000122	biological_process	negative regulation of transcription by RNA polymerase II
Q	0000791	cellular_component	euchromatin
Q	0000993	molecular_function	RNA polymerase II complex binding
Q	0001650	cellular_component	fibrillar center
Q	0001711	biological_process	endodermal cell fate commitment
Q	0001826	biological_process	inner cell mass cell differentiation
Q	0001829	biological_process	trophectodermal cell differentiation
Q	0001832	biological_process	blastocyst growth
Q	0001835	biological_process	blastocyst hatching
Q	0005515	molecular_function	protein binding
Q	0005634	cellular_component	nucleus
Q	0005654	cellular_component	nucleoplasm
Q	0005813	cellular_component	centrosome
Q	0006325	biological_process	chromatin organization
Q	0006368	biological_process	transcription elongation by RNA polymerase II
Q	0007259	biological_process	cell surface receptor signaling pathway via JAK-STAT
Q	0016055	biological_process	Wnt signaling pathway
Q	0016593	cellular_component	Cdc73/Paf1 complex
Q	0016607	cellular_component	nuclear speck
Q	0019827	biological_process	stem cell population maintenance
Q	0031124	biological_process	mRNA 3'-end processing
Q	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
Q	0042169	molecular_function	SH2 domain binding
Q	0045638	biological_process	negative regulation of myeloid cell differentiation
Q	0045814	biological_process	negative regulation of gene expression, epigenetic
Q	0045944	biological_process	positive regulation of transcription by RNA polymerase II
Q	0070102	biological_process	interleukin-6-mediated signaling pathway
Q	0071222	biological_process	cellular response to lipopolysaccharide
Q	1990269	molecular_function	RNA polymerase II C-terminal domain phosphoserine binding
U	0000122	biological_process	negative regulation of transcription by RNA polymerase II
U	0000791	cellular_component	euchromatin
U	0000993	molecular_function	RNA polymerase II complex binding
U	0001650	cellular_component	fibrillar center
U	0001711	biological_process	endodermal cell fate commitment
U	0001826	biological_process	inner cell mass cell differentiation
U	0001829	biological_process	trophectodermal cell differentiation
U	0001832	biological_process	blastocyst growth
U	0001835	biological_process	blastocyst hatching
U	0005515	molecular_function	protein binding
U	0005634	cellular_component	nucleus
U	0005654	cellular_component	nucleoplasm
U	0005813	cellular_component	centrosome
U	0006325	biological_process	chromatin organization
U	0006368	biological_process	transcription elongation by RNA polymerase II
U	0007259	biological_process	cell surface receptor signaling pathway via JAK-STAT
U	0016055	biological_process	Wnt signaling pathway
U	0016593	cellular_component	Cdc73/Paf1 complex
U	0016607	cellular_component	nuclear speck
U	0019827	biological_process	stem cell population maintenance
U	0031124	biological_process	mRNA 3'-end processing
U	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
U	0042169	molecular_function	SH2 domain binding
U	0045638	biological_process	negative regulation of myeloid cell differentiation
U	0045814	biological_process	negative regulation of gene expression, epigenetic
U	0045944	biological_process	positive regulation of transcription by RNA polymerase II
U	0070102	biological_process	interleukin-6-mediated signaling pathway
U	0071222	biological_process	cellular response to lipopolysaccharide
U	1990269	molecular_function	RNA polymerase II C-terminal domain phosphoserine binding
W	0000791	cellular_component	euchromatin
W	0005515	molecular_function	protein binding
W	0005634	cellular_component	nucleus
W	0005654	cellular_component	nucleoplasm
W	0005737	cellular_component	cytoplasm
W	0005829	cellular_component	cytosol
W	0006368	biological_process	transcription elongation by RNA polymerase II
W	0016055	biological_process	Wnt signaling pathway
W	0016593	cellular_component	Cdc73/Paf1 complex
W	0045638	biological_process	negative regulation of myeloid cell differentiation
W	0055087	cellular_component	Ski complex
W	0070478	biological_process	nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay
W	0072344	biological_process	rescue of stalled ribosome
X	0000122	biological_process	negative regulation of transcription by RNA polymerase II
X	0000781	cellular_component	chromosome, telomeric region
X	0000993	molecular_function	RNA polymerase II complex binding
X	0001558	biological_process	regulation of cell growth
X	0001711	biological_process	endodermal cell fate commitment
X	0005515	molecular_function	protein binding
X	0005634	cellular_component	nucleus
X	0005654	cellular_component	nucleoplasm
X	0005829	cellular_component	cytosol
X	0006357	biological_process	regulation of transcription by RNA polymerase II
X	0006368	biological_process	transcription elongation by RNA polymerase II
X	0008285	biological_process	negative regulation of cell population proliferation
X	0016055	biological_process	Wnt signaling pathway
X	0016593	cellular_component	Cdc73/Paf1 complex
X	0019827	biological_process	stem cell population maintenance
X	0030177	biological_process	positive regulation of Wnt signaling pathway
X	0031124	biological_process	mRNA 3'-end processing
X	0031442	biological_process	positive regulation of mRNA 3'-end processing
X	0031648	biological_process	protein destabilization
X	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
X	0043066	biological_process	negative regulation of apoptotic process
X	0045638	biological_process	negative regulation of myeloid cell differentiation
X	0045944	biological_process	positive regulation of transcription by RNA polymerase II
X	0048147	biological_process	negative regulation of fibroblast proliferation
X	0050680	biological_process	negative regulation of epithelial cell proliferation
X	0071222	biological_process	cellular response to lipopolysaccharide
X	1902808	biological_process	positive regulation of cell cycle G1/S phase transition
X	2000134	biological_process	negative regulation of G1/S transition of mitotic cell cycle
Y	0000993	molecular_function	RNA polymerase II complex binding
Y	0005634	cellular_component	nucleus
Y	0006368	biological_process	transcription elongation by RNA polymerase II
Y	0032044	cellular_component	DSIF complex
Y	0034244	biological_process	negative regulation of transcription elongation by RNA polymerase II
Y	0046872	molecular_function	metal ion binding
Z	0000122	biological_process	negative regulation of transcription by RNA polymerase II
Z	0003682	molecular_function	chromatin binding
Z	0003723	molecular_function	RNA binding
Z	0003729	molecular_function	mRNA binding
Z	0005515	molecular_function	protein binding
Z	0005634	cellular_component	nucleus
Z	0005654	cellular_component	nucleoplasm
Z	0006368	biological_process	transcription elongation by RNA polymerase II
Z	0016239	biological_process	positive regulation of macroautophagy
Z	0019899	molecular_function	enzyme binding
Z	0032044	cellular_component	DSIF complex
Z	0032785	biological_process	negative regulation of DNA-templated transcription, elongation
Z	0032786	biological_process	positive regulation of DNA-templated transcription, elongation
Z	0034243	biological_process	regulation of transcription elongation by RNA polymerase II
Z	0045944	biological_process	positive regulation of transcription by RNA polymerase II
Z	0046982	molecular_function	protein heterodimerization activity
a	0000786	cellular_component	nucleosome
a	0003677	molecular_function	DNA binding
a	0005515	molecular_function	protein binding
a	0005634	cellular_component	nucleus
a	0005654	cellular_component	nucleoplasm
a	0005694	cellular_component	chromosome
b	0000786	cellular_component	nucleosome
b	0003677	molecular_function	DNA binding
b	0005515	molecular_function	protein binding
b	0005634	cellular_component	nucleus
b	0005694	cellular_component	chromosome
e	0000786	cellular_component	nucleosome
e	0003677	molecular_function	DNA binding
e	0005515	molecular_function	protein binding
e	0005634	cellular_component	nucleus
e	0005654	cellular_component	nucleoplasm
e	0005694	cellular_component	chromosome
f	0000786	cellular_component	nucleosome
f	0003677	molecular_function	DNA binding
f	0005515	molecular_function	protein binding
f	0005634	cellular_component	nucleus
f	0005694	cellular_component	chromosome

Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DNDPSDYVEqdDI

Chain	Residue	Details
C	ASP136-ILE148

---

site_id	PS00046
Number of Residues	7
Details	HISTONE_H2A Histone H2A signature. AGLqFPV

Chain	Residue	Details
c	ALA21-VAL27

---

site_id	PS00047
Number of Residues	5
Details	HISTONE_H4 Histone H4 signature. GAKRH

Chain	Residue	Details
f	GLY14-HIS18

---

site_id	PS00115
Number of Residues	7
Details	RNA_POL_II_REPEAT Eukaryotic RNA polymerase II heptapeptide repeat. YSPTSPA

Chain	Residue	Details
A	TYR1593-ALA1599
A	TYR1671-SER1677
A	TYR1678-SER1684
A	TYR1685-SER1691
A	TYR1692-SER1698
A	TYR1699-SER1705
A	TYR1706-SER1712
A	TYR1713-SER1719
A	TYR1720-SER1726
A	TYR1727-SER1733
A	TYR1734-SER1740
A	TYR1615-SER1621
A	TYR1741-SER1747
A	TYR1748-SER1754
A	TYR1755-ASN1761
A	TYR1762-ASN1768
A	TYR1769-SER1775
A	TYR1776-SER1782
A	TYR1783-ASN1789
A	TYR1790-ASN1796
A	TYR1797-SER1803
A	TYR1804-SER1810
A	TYR1622-SER1628
A	TYR1811-SER1817
A	TYR1832-SER1838
A	TYR1839-SER1845
A	TYR1846-LYS1852
A	TYR1853-SER1859
A	TYR1867-LYS1873
A	TYR1874-LYS1880
A	TYR1881-LYS1887
A	TYR1888-THR1894
A	TYR1902-THR1908
A	TYR1629-ASN1635
A	TYR1916-LYS1922
A	TYR1923-THR1929
A	TYR1930-LYS1936
A	TYR1937-THR1943
A	TYR1944-LYS1950
A	TYR1961-THR1967
A	TYR1636-SER1642
A	TYR1643-SER1649
A	TYR1650-SER1656
A	TYR1657-SER1663
A	TYR1664-SER1670

---

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YVCTAPH

Chain	Residue	Details
I	TYR112-HIS118

---

site_id	PS00322
Number of Residues	7
Details	HISTONE_H3_1 Histone H3 signature 1. KAPRKQL

Chain	Residue	Details
e	LYS14-LEU20

---

site_id	PS00357
Number of Residues	23
Details	HISTONE_H2B Histone H2B signature. REIQTavRlLLpGELaKHAVSEG

Chain	Residue	Details
d	ARG89-GLY111

---

site_id	PS00446
Number of Residues	41
Details	RNA_POL_D_30KD RNA polymerases D / 30 to 40 Kd subunits signature. NSIRRvfiaevpiiAidwVqidaNsSvlhDEfIAhRLGLIP

Chain	Residue	Details
C	ASN32-PRO72

---

site_id	PS00466
Number of Residues	38
Details	ZF_TFIIS_1 Zinc finger TFIIS-type signature. CqkCghkeavffqSHSARaEDAmrlyyvCtaph.CghrW

Chain	Residue	Details
I	CYS86-TRP123

---

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. AASSslDaHIRLWDL

Chain	Residue	Details
W	ALA79-LEU93

---

site_id	PS00959
Number of Residues	9
Details	HISTONE_H3_2 Histone H3 signature 2. PFqRLVREI

Chain	Residue	Details
e	PRO66-ILE74

---

site_id	PS01030
Number of Residues	27
Details	RNA_POL_M_15KD RNA polymerases M / 15 Kd subunits signature. FCQECNNMLypkedkenrillyaCrnC

Chain	Residue	Details
I	PHE16-CYS42

---

site_id	PS01110
Number of Residues	14
Details	RNA_POL_H_23KD RNA polymerases H / 23 Kd subunits signature. HELVPEHvvMtkEE

Chain	Residue	Details
E	HIS142-GLU155

---

site_id	PS01111
Number of Residues	15
Details	RNA_POL_K_14KD RNA polymerases K / 14 to 18 Kd subunits signature. TkYErARvLGtRAlQ

Chain	Residue	Details
F	THR58-GLN72

---

site_id	PS01112
Number of Residues	10
Details	RNA_POL_N_8KD RNA polymerases N / 8 Kd subunits signature. IIPVrCFTCG

Chain	Residue	Details
J	ILE2-GLY11

---

site_id	PS01154
Number of Residues	32
Details	RNA_POL_L_13KD RNA polymerases L / 13 to 16 Kd subunits signature. InkEdHTLgNiIksqLlkdpqVlfagYkvpHP

Chain	Residue	Details
K	ILE35-PRO66

---

site_id	PS01166
Number of Residues	13
Details	RNA_POL_BETA RNA polymerases beta chain signature. GdKFASrHGQKGT

Chain	Residue	Details
B	GLY932-THR944

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	25
Details	ZN_FING: C4-type => ECO:0000255

Chain	Residue	Details
I	CYS17-CYS42
f	LYS16-LYS20
e	ARG2
e	ARG17

---

site_id	SWS_FT_FI2
Number of Residues	42
Details	ZN_FING: TFIIS-type => ECO:0000255|PROSITE-ProRule:PRU00472

Chain	Residue	Details
I	GLU82-THR124
f	SER1
Y	CYS33
Y	CYS36

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU10145

Chain	Residue	Details
I	CYS17
I	CYS20
I	CYS39
I	CYS42

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00472

Chain	Residue	Details
I	CYS86
I	CYS89
I	CYS114
I	CYS119

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: N-acetylmethionine => ECO:0000250|UniProtKB:P36954

Chain	Residue	Details
I	MET1
b	LYS16
b	LYS44
b	LYS79
f	LYS8
f	LYS16
f	LYS44
f	LYS79

---

site_id	SWS_FT_FI6
Number of Residues	4
Details	MOD_RES: N6-methyllysine; alternate => ECO:0000250|UniProtKB:P62805

Chain	Residue	Details
b	LYS12
U	SER-94
b	LYS20
f	LYS12
f	LYS20
Q	SER1085
U	SER-140
U	SER-138
U	SER-136
U	SER-98

---

site_id	SWS_FT_FI7
Number of Residues	4
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P62805

Chain	Residue	Details
b	LYS31
b	LYS91
f	LYS31
f	LYS91

---

site_id	SWS_FT_FI8
Number of Residues	2
Details	MOD_RES: Phosphoserine; by PAK2 => ECO:0000250|UniProtKB:P62805

Chain	Residue	Details
b	SER47
f	SER47
U	SER-82
U	SER-77

---

site_id	SWS_FT_FI9
Number of Residues	4
Details	MOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:P62805

Chain	Residue	Details
b	TYR51
b	TYR88
f	TYR51
f	TYR88

---

site_id	SWS_FT_FI10
Number of Residues	2
Details	MOD_RES: N6-glutaryllysine; alternate => ECO:0000250|UniProtKB:P62805

Chain	Residue	Details
b	LYS59
e	LYS64
f	LYS59
a	LYS27
a	LYS36
a	LYS64
e	LYS18
e	LYS23
e	LYS27
e	LYS36

---

site_id	SWS_FT_FI11
Number of Residues	2
Details	MOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:P62805

Chain	Residue	Details
b	LYS77
U	SER220
f	LYS77
Q	SER1333
Q	SER1391
Q	SER1399
U	SER14
U	SER151
U	SER154
U	SER212

---

site_id	SWS_FT_FI12
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in UFM1); alternate => ECO:0000250|UniProtKB:P62805

Chain	Residue	Details
b	LYS31
f	LYS31

---

site_id	SWS_FT_FI13
Number of Residues	4
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate => ECO:0000250|UniProtKB:P62805

Chain	Residue	Details
a	LYS37
b	LYS91
Q	SER1358
f	LYS91
U	SER171
U	SER179

---

site_id	SWS_FT_FI14
Number of Residues	2
Details	MOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:Q71DI3

Chain	Residue	Details
a	TYR41
e	TYR41

---

site_id	SWS_FT_FI15
Number of Residues	4
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P84228

Chain	Residue	Details
a	LYS56
a	LYS79
e	LYS56
e	LYS79

---

site_id	SWS_FT_FI16
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q71DI3

Chain	Residue	Details
a	SER57
e	SER57

---

site_id	SWS_FT_FI17
Number of Residues	4
Details	MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:Q71DI3

Chain	Residue	Details
a	THR80
a	THR107
e	THR80
e	THR107

---

site_id	SWS_FT_FI18
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P84243

Chain	Residue	Details
a	SER86
e	SER86

---

site_id	SWS_FT_FI19
Number of Residues	2
Details	MOD_RES: N6-glutaryllysine; alternate => ECO:0000250|UniProtKB:Q71DI3

Chain	Residue	Details
a	LYS115
e	LYS115
U	SER294
U	SER617

---

site_id	SWS_FT_FI20
Number of Residues	2
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:Q71DI3

Chain	Residue	Details
a	LYS122
e	LYS122

---

site_id	SWS_FT_FI21
Number of Residues	2
Details	LIPID: S-palmitoyl cysteine => ECO:0000250|UniProtKB:Q71DI3

Chain	Residue	Details
a	CYS110
e	CYS110

---

site_id	SWS_FT_FI22
Number of Residues	2
Details	MOD_RES: Phosphotyrosine => ECO:0007744|PubMed:24275569

Chain	Residue	Details
Q	TYR1785
U	TYR613

---

site_id	SWS_FT_FI23
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:21406692

Chain	Residue	Details
Q	SER1786
Q	SER1787
U	SER614
U	SER615

---

site_id	SWS_FT_FI24
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648

Chain	Residue	Details
Q	SER1793
U	SER621

---

site_id	SWS_FT_FI25
Number of Residues	2
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332

Chain	Residue	Details
Q	THR1808
U	THR636

---

site_id	SWS_FT_FI26
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
Q	SER1809
U	SER637

---

site_id	SWS_FT_FI27
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:18318008, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
Q	SER1837
U	SER665

---