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7ZSA

Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome and NTP (complex B)

Functional Information from GO Data
ChainGOidnamespacecontents
00000019biological_processregulation of mitotic recombination
00000112cellular_componentnucleotide-excision repair factor 3 complex
00000439cellular_componenttranscription factor TFIIH core complex
00003676molecular_functionnucleic acid binding
00003677molecular_functionDNA binding
00003678molecular_functionDNA helicase activity
00003684molecular_functiondamaged DNA binding
00004386molecular_functionhelicase activity
00005515molecular_functionprotein binding
00005524molecular_functionATP binding
00005634cellular_componentnucleus
00005675cellular_componenttranscription factor TFIIH holo complex
00005829cellular_componentcytosol
00006139biological_processnucleobase-containing compound metabolic process
00006281biological_processDNA repair
00006289biological_processnucleotide-excision repair
00006366biological_processtranscription by RNA polymerase II
00006367biological_processtranscription initiation at RNA polymerase II promoter
00006974biological_processDNA damage response
00008094molecular_functionATP-dependent activity, acting on DNA
00016787molecular_functionhydrolase activity
00016818molecular_functionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
00016853molecular_functionisomerase activity
00016887molecular_functionATP hydrolysis activity
00032508biological_processDNA duplex unwinding
00032991cellular_componentprotein-containing complex
00043139molecular_function5'-3' DNA helicase activity
00045951biological_processpositive regulation of mitotic recombination
00046872molecular_functionmetal ion binding
00051539molecular_function4 iron, 4 sulfur cluster binding
10000112cellular_componentnucleotide-excision repair factor 3 complex
10000439cellular_componenttranscription factor TFIIH core complex
10005515molecular_functionprotein binding
10005634cellular_componentnucleus
10005675cellular_componenttranscription factor TFIIH holo complex
10005829cellular_componentcytosol
10006281biological_processDNA repair
10006289biological_processnucleotide-excision repair
10006351biological_processDNA-templated transcription
10006360biological_processtranscription by RNA polymerase I
10006366biological_processtranscription by RNA polymerase II
10006367biological_processtranscription initiation at RNA polymerase II promoter
10010314molecular_functionphosphatidylinositol-5-phosphate binding
10032266molecular_functionphosphatidylinositol-3-phosphate binding
20000112cellular_componentnucleotide-excision repair factor 3 complex
20000439cellular_componenttranscription factor TFIIH core complex
20001671molecular_functionATPase activator activity
20003690molecular_functiondouble-stranded DNA binding
20005515molecular_functionprotein binding
20005634cellular_componentnucleus
20005675cellular_componenttranscription factor TFIIH holo complex
20006281biological_processDNA repair
20006289biological_processnucleotide-excision repair
20006366biological_processtranscription by RNA polymerase II
20006367biological_processtranscription initiation at RNA polymerase II promoter
30000993molecular_functionRNA polymerase II complex binding
30005634cellular_componentnucleus
30005675cellular_componenttranscription factor TFIIH holo complex
30006281biological_processDNA repair
30006289biological_processnucleotide-excision repair
30006357biological_processregulation of transcription by RNA polymerase II
30006366biological_processtranscription by RNA polymerase II
30006367biological_processtranscription initiation at RNA polymerase II promoter
30008270molecular_functionzinc ion binding
30045737biological_processpositive regulation of cyclin-dependent protein serine/threonine kinase activity
30046872molecular_functionmetal ion binding
30061575molecular_functioncyclin-dependent protein serine/threonine kinase activator activity
30070985cellular_componenttranscription factor TFIIK complex
40000112cellular_componentnucleotide-excision repair factor 3 complex
40000439cellular_componenttranscription factor TFIIH core complex
40005634cellular_componentnucleus
40005675cellular_componenttranscription factor TFIIH holo complex
40006281biological_processDNA repair
40006289biological_processnucleotide-excision repair
40006355biological_processregulation of DNA-templated transcription
40006366biological_processtranscription by RNA polymerase II
40006367biological_processtranscription initiation at RNA polymerase II promoter
40008270molecular_functionzinc ion binding
40016251molecular_functionRNA polymerase II general transcription initiation factor activity
40046872molecular_functionmetal ion binding
50000439cellular_componenttranscription factor TFIIH core complex
50000993molecular_functionRNA polymerase II complex binding
50005515molecular_functionprotein binding
50005634cellular_componentnucleus
50005675cellular_componenttranscription factor TFIIH holo complex
50005829cellular_componentcytosol
50006281biological_processDNA repair
50006289biological_processnucleotide-excision repair
50006294biological_processnucleotide-excision repair, preincision complex assembly
50006366biological_processtranscription by RNA polymerase II
50006367biological_processtranscription initiation at RNA polymerase II promoter
60000112cellular_componentnucleotide-excision repair factor 3 complex
60000439cellular_componenttranscription factor TFIIH core complex
60005634cellular_componentnucleus
60005675cellular_componenttranscription factor TFIIH holo complex
60006281biological_processDNA repair
60006289biological_processnucleotide-excision repair
60006351biological_processDNA-templated transcription
60006357biological_processregulation of transcription by RNA polymerase II
60006366biological_processtranscription by RNA polymerase II
60006367biological_processtranscription initiation at RNA polymerase II promoter
60008270molecular_functionzinc ion binding
60046872molecular_functionmetal ion binding
60061630molecular_functionubiquitin protein ligase activity
70000019biological_processregulation of mitotic recombination
70000112cellular_componentnucleotide-excision repair factor 3 complex
70000439cellular_componenttranscription factor TFIIH core complex
70001111biological_processRNA polymerase II promoter clearance
70001113biological_processtranscription open complex formation at RNA polymerase II promoter
70001174biological_processtranscriptional start site selection at RNA polymerase II promoter
70003677molecular_functionDNA binding
70003678molecular_functionDNA helicase activity
70004386molecular_functionhelicase activity
70005524molecular_functionATP binding
70005634cellular_componentnucleus
70005675cellular_componenttranscription factor TFIIH holo complex
70005829cellular_componentcytosol
70006281biological_processDNA repair
70006289biological_processnucleotide-excision repair
70006366biological_processtranscription by RNA polymerase II
70006367biological_processtranscription initiation at RNA polymerase II promoter
70015616molecular_functionDNA translocase activity
70016787molecular_functionhydrolase activity
70016853molecular_functionisomerase activity
70016887molecular_functionATP hydrolysis activity
70016973biological_processpoly(A)+ mRNA export from nucleus
70032508biological_processDNA duplex unwinding
70043138molecular_function3'-5' DNA helicase activity
70097550cellular_componenttranscription preinitiation complex
A0000428cellular_componentDNA-directed RNA polymerase complex
A0001055molecular_functionRNA polymerase II activity
A0001172biological_processRNA-templated transcription
A0003677molecular_functionDNA binding
A0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
A0003968molecular_functionRNA-dependent RNA polymerase activity
A0005515molecular_functionprotein binding
A0005634cellular_componentnucleus
A0005665cellular_componentRNA polymerase II, core complex
A0005739cellular_componentmitochondrion
A0006351biological_processDNA-templated transcription
A0006366biological_processtranscription by RNA polymerase II
A0006367biological_processtranscription initiation at RNA polymerase II promoter
A0006368biological_processtranscription elongation by RNA polymerase II
A0008270molecular_functionzinc ion binding
A0010494cellular_componentcytoplasmic stress granule
A0016779molecular_functionnucleotidyltransferase activity
A0019985biological_processtranslesion synthesis
A0034062molecular_function5'-3' RNA polymerase activity
A0046872molecular_functionmetal ion binding
B0000428cellular_componentDNA-directed RNA polymerase complex
B0001055molecular_functionRNA polymerase II activity
B0001172biological_processRNA-templated transcription
B0003677molecular_functionDNA binding
B0003729molecular_functionmRNA binding
B0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
B0003968molecular_functionRNA-dependent RNA polymerase activity
B0005515molecular_functionprotein binding
B0005634cellular_componentnucleus
B0005654cellular_componentnucleoplasm
B0005665cellular_componentRNA polymerase II, core complex
B0005739cellular_componentmitochondrion
B0006351biological_processDNA-templated transcription
B0006366biological_processtranscription by RNA polymerase II
B0006367biological_processtranscription initiation at RNA polymerase II promoter
B0006368biological_processtranscription elongation by RNA polymerase II
B0008270molecular_functionzinc ion binding
B0010494cellular_componentcytoplasmic stress granule
B0016779molecular_functionnucleotidyltransferase activity
B0032549molecular_functionribonucleoside binding
B0034062molecular_function5'-3' RNA polymerase activity
B0046872molecular_functionmetal ion binding
C0000428cellular_componentDNA-directed RNA polymerase complex
C0001055molecular_functionRNA polymerase II activity
C0001172biological_processRNA-templated transcription
C0003677molecular_functionDNA binding
C0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
C0003968molecular_functionRNA-dependent RNA polymerase activity
C0005515molecular_functionprotein binding
C0005634cellular_componentnucleus
C0005654cellular_componentnucleoplasm
C0005665cellular_componentRNA polymerase II, core complex
C0006351biological_processDNA-templated transcription
C0006366biological_processtranscription by RNA polymerase II
C0006367biological_processtranscription initiation at RNA polymerase II promoter
C0006368biological_processtranscription elongation by RNA polymerase II
C0006369biological_processtermination of RNA polymerase II transcription
C0008270molecular_functionzinc ion binding
C0046872molecular_functionmetal ion binding
C0046983molecular_functionprotein dimerization activity
C0055029cellular_componentnuclear DNA-directed RNA polymerase complex
D0000166molecular_functionnucleotide binding
D0000288biological_processnuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
D0000428cellular_componentDNA-directed RNA polymerase complex
D0000932cellular_componentP-body
D0001172biological_processRNA-templated transcription
D0003697molecular_functionsingle-stranded DNA binding
D0003727molecular_functionsingle-stranded RNA binding
D0003968molecular_functionRNA-dependent RNA polymerase activity
D0005515molecular_functionprotein binding
D0005634cellular_componentnucleus
D0005665cellular_componentRNA polymerase II, core complex
D0005737cellular_componentcytoplasm
D0006352biological_processDNA-templated transcription initiation
D0006366biological_processtranscription by RNA polymerase II
D0006367biological_processtranscription initiation at RNA polymerase II promoter
D0006368biological_processtranscription elongation by RNA polymerase II
D0006397biological_processmRNA processing
D0030880cellular_componentRNA polymerase complex
D0031369molecular_functiontranslation initiation factor binding
D0044237biological_processcellular metabolic process
D0045948biological_processpositive regulation of translational initiation
D1990328cellular_componentRPB4-RPB7 complex
E0000428cellular_componentDNA-directed RNA polymerase complex
E0001054molecular_functionRNA polymerase I activity
E0001055molecular_functionRNA polymerase II activity
E0001056molecular_functionRNA polymerase III activity
E0001172biological_processRNA-templated transcription
E0003677molecular_functionDNA binding
E0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
E0003968molecular_functionRNA-dependent RNA polymerase activity
E0005515molecular_functionprotein binding
E0005634cellular_componentnucleus
E0005654cellular_componentnucleoplasm
E0005665cellular_componentRNA polymerase II, core complex
E0005666cellular_componentRNA polymerase III complex
E0005736cellular_componentRNA polymerase I complex
E0006351biological_processDNA-templated transcription
E0006360biological_processtranscription by RNA polymerase I
E0006361biological_processtranscription initiation at RNA polymerase I promoter
E0006362biological_processtranscription elongation by RNA polymerase I
E0006363biological_processtermination of RNA polymerase I transcription
E0006366biological_processtranscription by RNA polymerase II
E0006367biological_processtranscription initiation at RNA polymerase II promoter
E0006368biological_processtranscription elongation by RNA polymerase II
E0006383biological_processtranscription by RNA polymerase III
E0006384biological_processtranscription initiation at RNA polymerase III promoter
E0006386biological_processtermination of RNA polymerase III transcription
E0042254biological_processribosome biogenesis
E0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
E0042797biological_processtRNA transcription by RNA polymerase III
F0000428cellular_componentDNA-directed RNA polymerase complex
F0001054molecular_functionRNA polymerase I activity
F0001055molecular_functionRNA polymerase II activity
F0001056molecular_functionRNA polymerase III activity
F0001172biological_processRNA-templated transcription
F0003677molecular_functionDNA binding
F0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
F0003968molecular_functionRNA-dependent RNA polymerase activity
F0005515molecular_functionprotein binding
F0005634cellular_componentnucleus
F0005654cellular_componentnucleoplasm
F0005665cellular_componentRNA polymerase II, core complex
F0005666cellular_componentRNA polymerase III complex
F0005736cellular_componentRNA polymerase I complex
F0005737cellular_componentcytoplasm
F0006351biological_processDNA-templated transcription
F0006360biological_processtranscription by RNA polymerase I
F0006361biological_processtranscription initiation at RNA polymerase I promoter
F0006362biological_processtranscription elongation by RNA polymerase I
F0006363biological_processtermination of RNA polymerase I transcription
F0006366biological_processtranscription by RNA polymerase II
F0006367biological_processtranscription initiation at RNA polymerase II promoter
F0006368biological_processtranscription elongation by RNA polymerase II
F0006383biological_processtranscription by RNA polymerase III
F0006384biological_processtranscription initiation at RNA polymerase III promoter
F0006386biological_processtermination of RNA polymerase III transcription
F0042254biological_processribosome biogenesis
F0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
F0042797biological_processtRNA transcription by RNA polymerase III
G0000288biological_processnuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
G0000428cellular_componentDNA-directed RNA polymerase complex
G0000932cellular_componentP-body
G0000956biological_processnuclear-transcribed mRNA catabolic process
G0001172biological_processRNA-templated transcription
G0003676molecular_functionnucleic acid binding
G0003697molecular_functionsingle-stranded DNA binding
G0003727molecular_functionsingle-stranded RNA binding
G0003968molecular_functionRNA-dependent RNA polymerase activity
G0005515molecular_functionprotein binding
G0005634cellular_componentnucleus
G0005665cellular_componentRNA polymerase II, core complex
G0005737cellular_componentcytoplasm
G0006351biological_processDNA-templated transcription
G0006352biological_processDNA-templated transcription initiation
G0006366biological_processtranscription by RNA polymerase II
G0006367biological_processtranscription initiation at RNA polymerase II promoter
G0006368biological_processtranscription elongation by RNA polymerase II
G0031369molecular_functiontranslation initiation factor binding
G0045948biological_processpositive regulation of translational initiation
G0055029cellular_componentnuclear DNA-directed RNA polymerase complex
G0060213biological_processpositive regulation of nuclear-transcribed mRNA poly(A) tail shortening
G1990328cellular_componentRPB4-RPB7 complex
H0000428cellular_componentDNA-directed RNA polymerase complex
H0001054molecular_functionRNA polymerase I activity
H0001055molecular_functionRNA polymerase II activity
H0001056molecular_functionRNA polymerase III activity
H0001172biological_processRNA-templated transcription
H0003677molecular_functionDNA binding
H0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
H0003968molecular_functionRNA-dependent RNA polymerase activity
H0005515molecular_functionprotein binding
H0005634cellular_componentnucleus
H0005654cellular_componentnucleoplasm
H0005665cellular_componentRNA polymerase II, core complex
H0005666cellular_componentRNA polymerase III complex
H0005736cellular_componentRNA polymerase I complex
H0006351biological_processDNA-templated transcription
H0006360biological_processtranscription by RNA polymerase I
H0006361biological_processtranscription initiation at RNA polymerase I promoter
H0006362biological_processtranscription elongation by RNA polymerase I
H0006363biological_processtermination of RNA polymerase I transcription
H0006366biological_processtranscription by RNA polymerase II
H0006367biological_processtranscription initiation at RNA polymerase II promoter
H0006368biological_processtranscription elongation by RNA polymerase II
H0006383biological_processtranscription by RNA polymerase III
H0006384biological_processtranscription initiation at RNA polymerase III promoter
H0006386biological_processtermination of RNA polymerase III transcription
H0042254biological_processribosome biogenesis
H0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
H0042797biological_processtRNA transcription by RNA polymerase III
I0000428cellular_componentDNA-directed RNA polymerase complex
I0001172biological_processRNA-templated transcription
I0001193biological_processmaintenance of transcriptional fidelity during transcription elongation by RNA polymerase II
I0003676molecular_functionnucleic acid binding
I0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
I0003968molecular_functionRNA-dependent RNA polymerase activity
I0005515molecular_functionprotein binding
I0005634cellular_componentnucleus
I0005654cellular_componentnucleoplasm
I0005665cellular_componentRNA polymerase II, core complex
I0005730cellular_componentnucleolus
I0006281biological_processDNA repair
I0006283biological_processtranscription-coupled nucleotide-excision repair
I0006351biological_processDNA-templated transcription
I0006366biological_processtranscription by RNA polymerase II
I0006367biological_processtranscription initiation at RNA polymerase II promoter
I0006368biological_processtranscription elongation by RNA polymerase II
I0008270molecular_functionzinc ion binding
I0046872molecular_functionmetal ion binding
I0055029cellular_componentnuclear DNA-directed RNA polymerase complex
J0000428cellular_componentDNA-directed RNA polymerase complex
J0001054molecular_functionRNA polymerase I activity
J0001055molecular_functionRNA polymerase II activity
J0001056molecular_functionRNA polymerase III activity
J0001172biological_processRNA-templated transcription
J0003677molecular_functionDNA binding
J0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
J0003968molecular_functionRNA-dependent RNA polymerase activity
J0005515molecular_functionprotein binding
J0005634cellular_componentnucleus
J0005654cellular_componentnucleoplasm
J0005665cellular_componentRNA polymerase II, core complex
J0005666cellular_componentRNA polymerase III complex
J0005730cellular_componentnucleolus
J0005736cellular_componentRNA polymerase I complex
J0006351biological_processDNA-templated transcription
J0006360biological_processtranscription by RNA polymerase I
J0006361biological_processtranscription initiation at RNA polymerase I promoter
J0006362biological_processtranscription elongation by RNA polymerase I
J0006363biological_processtermination of RNA polymerase I transcription
J0006366biological_processtranscription by RNA polymerase II
J0006367biological_processtranscription initiation at RNA polymerase II promoter
J0006368biological_processtranscription elongation by RNA polymerase II
J0006383biological_processtranscription by RNA polymerase III
J0006384biological_processtranscription initiation at RNA polymerase III promoter
J0006386biological_processtermination of RNA polymerase III transcription
J0008270molecular_functionzinc ion binding
J0042254biological_processribosome biogenesis
J0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
J0042797biological_processtRNA transcription by RNA polymerase III
J0046872molecular_functionmetal ion binding
K0000428cellular_componentDNA-directed RNA polymerase complex
K0001055molecular_functionRNA polymerase II activity
K0001172biological_processRNA-templated transcription
K0003677molecular_functionDNA binding
K0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
K0003968molecular_functionRNA-dependent RNA polymerase activity
K0005515molecular_functionprotein binding
K0005634cellular_componentnucleus
K0005665cellular_componentRNA polymerase II, core complex
K0006351biological_processDNA-templated transcription
K0006366biological_processtranscription by RNA polymerase II
K0006367biological_processtranscription initiation at RNA polymerase II promoter
K0006368biological_processtranscription elongation by RNA polymerase II
K0006369biological_processtermination of RNA polymerase II transcription
K0046983molecular_functionprotein dimerization activity
L0000428cellular_componentDNA-directed RNA polymerase complex
L0001054molecular_functionRNA polymerase I activity
L0001055molecular_functionRNA polymerase II activity
L0001056molecular_functionRNA polymerase III activity
L0001172biological_processRNA-templated transcription
L0003677molecular_functionDNA binding
L0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
L0003968molecular_functionRNA-dependent RNA polymerase activity
L0005634cellular_componentnucleus
L0005654cellular_componentnucleoplasm
L0005665cellular_componentRNA polymerase II, core complex
L0005666cellular_componentRNA polymerase III complex
L0005730cellular_componentnucleolus
L0005736cellular_componentRNA polymerase I complex
L0005737cellular_componentcytoplasm
L0005777cellular_componentperoxisome
L0006351biological_processDNA-templated transcription
L0006360biological_processtranscription by RNA polymerase I
L0006361biological_processtranscription initiation at RNA polymerase I promoter
L0006362biological_processtranscription elongation by RNA polymerase I
L0006363biological_processtermination of RNA polymerase I transcription
L0006366biological_processtranscription by RNA polymerase II
L0006367biological_processtranscription initiation at RNA polymerase II promoter
L0006368biological_processtranscription elongation by RNA polymerase II
L0006383biological_processtranscription by RNA polymerase III
L0006384biological_processtranscription initiation at RNA polymerase III promoter
L0006386biological_processtermination of RNA polymerase III transcription
L0008270molecular_functionzinc ion binding
L0042254biological_processribosome biogenesis
L0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
L0042797biological_processtRNA transcription by RNA polymerase III
L0046872molecular_functionmetal ion binding
M0000993molecular_functionRNA polymerase II complex binding
M0001113biological_processtranscription open complex formation at RNA polymerase II promoter
M0001139molecular_functionRNA polymerase II complex recruiting activity
M0001174biological_processtranscriptional start site selection at RNA polymerase II promoter
M0005515molecular_functionprotein binding
M0005634cellular_componentnucleus
M0006352biological_processDNA-templated transcription initiation
M0006367biological_processtranscription initiation at RNA polymerase II promoter
M0008270molecular_functionzinc ion binding
M0010467biological_processgene expression
M0016251molecular_functionRNA polymerase II general transcription initiation factor activity
M0017025molecular_functionTBP-class protein binding
M0046872molecular_functionmetal ion binding
M0051123biological_processRNA polymerase II preinitiation complex assembly
M0070897biological_processtranscription preinitiation complex assembly
M0097550cellular_componenttranscription preinitiation complex
O0000126cellular_componenttranscription factor TFIIIB complex
O0000979molecular_functionRNA polymerase II core promoter sequence-specific DNA binding
O0001016molecular_functionRNA polymerase III transcription regulatory region sequence-specific DNA binding
O0001092molecular_functionTFIIA-class transcription factor complex binding
O0001179molecular_functionRNA polymerase I general transcription initiation factor binding
O0001188biological_processRNA polymerase I preinitiation complex assembly
O0003677molecular_functionDNA binding
O0003682molecular_functionchromatin binding
O0005515molecular_functionprotein binding
O0005634cellular_componentnucleus
O0005654cellular_componentnucleoplasm
O0005667cellular_componenttranscription regulator complex
O0005669cellular_componenttranscription factor TFIID complex
O0005672cellular_componenttranscription factor TFIIA complex
O0006352biological_processDNA-templated transcription initiation
O0006359biological_processregulation of transcription by RNA polymerase III
O0008301molecular_functionDNA binding, bending
O0016251molecular_functionRNA polymerase II general transcription initiation factor activity
O0032991cellular_componentprotein-containing complex
O0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
O0045892biological_processnegative regulation of DNA-templated transcription
O0045944biological_processpositive regulation of transcription by RNA polymerase II
O0051123biological_processRNA polymerase II preinitiation complex assembly
O0061629molecular_functionRNA polymerase II-specific DNA-binding transcription factor binding
O0070898biological_processRNA polymerase III preinitiation complex assembly
O0097718molecular_functiondisordered domain specific binding
O0140297molecular_functionDNA-binding transcription factor binding
Q0001096molecular_functionTFIIF-class transcription factor complex binding
Q0001174biological_processtranscriptional start site selection at RNA polymerase II promoter
Q0003677molecular_functionDNA binding
Q0005634cellular_componentnucleus
Q0005674cellular_componenttranscription factor TFIIF complex
Q0006355biological_processregulation of DNA-templated transcription
Q0006367biological_processtranscription initiation at RNA polymerase II promoter
Q0006368biological_processtranscription elongation by RNA polymerase II
Q0016251molecular_functionRNA polymerase II general transcription initiation factor activity
Q0032968biological_processpositive regulation of transcription elongation by RNA polymerase II
Q0051123biological_processRNA polymerase II preinitiation complex assembly
Q0072542molecular_functionprotein phosphatase activator activity
R0000166molecular_functionnucleotide binding
R0000993molecular_functionRNA polymerase II complex binding
R0001174biological_processtranscriptional start site selection at RNA polymerase II promoter
R0003677molecular_functionDNA binding
R0005515molecular_functionprotein binding
R0005634cellular_componentnucleus
R0005674cellular_componenttranscription factor TFIIF complex
R0006355biological_processregulation of DNA-templated transcription
R0006366biological_processtranscription by RNA polymerase II
R0006367biological_processtranscription initiation at RNA polymerase II promoter
R0006368biological_processtranscription elongation by RNA polymerase II
R0051123biological_processRNA polymerase II preinitiation complex assembly
U0005672cellular_componenttranscription factor TFIIA complex
U0006367biological_processtranscription initiation at RNA polymerase II promoter
V0000979molecular_functionRNA polymerase II core promoter sequence-specific DNA binding
V0005515molecular_functionprotein binding
V0005634cellular_componentnucleus
V0005672cellular_componenttranscription factor TFIIA complex
V0005737cellular_componentcytoplasm
V0006367biological_processtranscription initiation at RNA polymerase II promoter
V0016251molecular_functionRNA polymerase II general transcription initiation factor activity
V0017025molecular_functionTBP-class protein binding
V0045944biological_processpositive regulation of transcription by RNA polymerase II
V0051123biological_processRNA polymerase II preinitiation complex assembly
V0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
W0000993molecular_functionRNA polymerase II complex binding
W0001097molecular_functionTFIIH-class transcription factor complex binding
W0001113biological_processtranscription open complex formation at RNA polymerase II promoter
W0003697molecular_functionsingle-stranded DNA binding
W0005515molecular_functionprotein binding
W0005634cellular_componentnucleus
W0005673cellular_componenttranscription factor TFIIE complex
W0005739cellular_componentmitochondrion
W0006366biological_processtranscription by RNA polymerase II
W0006367biological_processtranscription initiation at RNA polymerase II promoter
W0008270molecular_functionzinc ion binding
W0046872molecular_functionmetal ion binding
W0097550cellular_componenttranscription preinitiation complex
X0000993molecular_functionRNA polymerase II complex binding
X0001097molecular_functionTFIIH-class transcription factor complex binding
X0003677molecular_functionDNA binding
X0003697molecular_functionsingle-stranded DNA binding
X0005515molecular_functionprotein binding
X0005634cellular_componentnucleus
X0005673cellular_componenttranscription factor TFIIE complex
X0006366biological_processtranscription by RNA polymerase II
X0006367biological_processtranscription initiation at RNA polymerase II promoter
X0097550cellular_componenttranscription preinitiation complex
a0000786cellular_componentnucleosome
a0003677molecular_functionDNA binding
a0005515molecular_functionprotein binding
a0005634cellular_componentnucleus
a0005654cellular_componentnucleoplasm
a0005694cellular_componentchromosome
a0030527molecular_functionstructural constituent of chromatin
a0046982molecular_functionprotein heterodimerization activity
b0000786cellular_componentnucleosome
b0003677molecular_functionDNA binding
b0005515molecular_functionprotein binding
b0005634cellular_componentnucleus
b0005694cellular_componentchromosome
b0006334biological_processnucleosome assembly
b0030527molecular_functionstructural constituent of chromatin
b0046982molecular_functionprotein heterodimerization activity
c0000786cellular_componentnucleosome
c0003677molecular_functionDNA binding
c0005634cellular_componentnucleus
c0005694cellular_componentchromosome
c0030527molecular_functionstructural constituent of chromatin
c0046982molecular_functionprotein heterodimerization activity
d0000786cellular_componentnucleosome
d0003677molecular_functionDNA binding
d0005515molecular_functionprotein binding
d0005634cellular_componentnucleus
d0005694cellular_componentchromosome
d0030527molecular_functionstructural constituent of chromatin
d0046982molecular_functionprotein heterodimerization activity
e0000786cellular_componentnucleosome
e0003677molecular_functionDNA binding
e0005515molecular_functionprotein binding
e0005634cellular_componentnucleus
e0005654cellular_componentnucleoplasm
e0005694cellular_componentchromosome
e0030527molecular_functionstructural constituent of chromatin
e0046982molecular_functionprotein heterodimerization activity
f0000786cellular_componentnucleosome
f0003677molecular_functionDNA binding
f0005515molecular_functionprotein binding
f0005634cellular_componentnucleus
f0005694cellular_componentchromosome
f0006334biological_processnucleosome assembly
f0030527molecular_functionstructural constituent of chromatin
f0046982molecular_functionprotein heterodimerization activity
g0000786cellular_componentnucleosome
g0003677molecular_functionDNA binding
g0005634cellular_componentnucleus
g0005694cellular_componentchromosome
g0030527molecular_functionstructural constituent of chromatin
g0046982molecular_functionprotein heterodimerization activity
h0000786cellular_componentnucleosome
h0003677molecular_functionDNA binding
h0005515molecular_functionprotein binding
h0005634cellular_componentnucleus
h0005694cellular_componentchromosome
h0030527molecular_functionstructural constituent of chromatin
h0046982molecular_functionprotein heterodimerization activity
Functional Information from PROSITE/UniProt
site_idPS00014
Number of Residues4
DetailsER_TARGET Endoplasmic reticulum targeting sequence. SEEL
ChainResidueDetails
3SER318-LEU321

site_idPS00028
Number of Residues21
DetailsZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. Ced..CkqeFcvdcdvfiHeil..H
ChainResidueDetails
6CYS429-HIS449

site_idPS00046
Number of Residues7
DetailsHISTONE_H2A Histone H2A signature. AGLqFPV
ChainResidueDetails
cALA21-VAL27

site_idPS00047
Number of Residues5
DetailsHISTONE_H4 Histone H4 signature. GAKRH
ChainResidueDetails
bGLY14-HIS18

site_idPS00115
Number of Residues7
DetailsRNA_POL_II_REPEAT Eukaryotic RNA polymerase II heptapeptide repeat. YSPTSPA
ChainResidueDetails
ATYR1549-ALA1555
ATYR1612-SER1618
ATYR1619-SER1625
ATYR1626-SER1632
ATYR1633-SER1639
ATYR1640-SER1646
ATYR1647-SER1653
ATYR1654-ALA1660
ATYR1661-SER1667
ATYR1668-SER1674
ATYR1675-SER1681
ATYR1556-SER1562
ATYR1682-SER1688
ATYR1689-ASN1695
ATYR1696-SER1702
ATYR1563-SER1569
ATYR1570-SER1576
ATYR1577-SER1583
ATYR1584-SER1590
ATYR1591-SER1597
ATYR1598-SER1604
ATYR1605-SER1611

site_idPS00322
Number of Residues7
DetailsHISTONE_H3_1 Histone H3 signature 1. KAPRKQL
ChainResidueDetails
aLYS14-LEU20

site_idPS00351
Number of Residues50
DetailsTFIID Transcription factor TFIID repeat signature. YnPkrFaaVImRirePKttaLIFaSGKMvvtGAKseddsklAsrkyariI
ChainResidueDetails
OTYR94-ILE143
OTYR185-LEU234

site_idPS00357
Number of Residues23
DetailsHISTONE_H2B Histone H2B signature. REIQTavRlLLpGELaKHAVSEG
ChainResidueDetails
dARG89-GLY111

site_idPS00387
Number of Residues7
DetailsPPASE Inorganic pyrophosphatase signature. DDDEMDI
ChainResidueDetails
WASP471-ILE477

site_idPS00446
Number of Residues41
DetailsRNA_POL_D_30KD RNA polymerases D / 30 to 40 Kd subunits signature. NSLRRvmiaeiptlAidsVevetNtTvlaDEfIAhRLGLIP
ChainResidueDetails
CASN31-PRO71

site_idPS00466
Number of Residues36
DetailsZF_TFIIS_1 Zinc finger TFIIS-type signature. CpkChsrenvffqSQQRRkDTSmvlffvCls...CshiF
ChainResidueDetails
ICYS75-PHE110

site_idPS00518
Number of Residues10
DetailsZF_RING_1 Zinc finger RING-type signature. CyHrICesCV
ChainResidueDetails
3CYS34-VAL43

site_idPS00690
Number of Residues10
DetailsDEAH_ATP_HELICASE DEAH-box subfamily ATP-dependent helicases signature. SiVIFDEAHN
ChainResidueDetails
0SER230-ASN239

site_idPS00782
Number of Residues16
DetailsTFIIB Transcription factor TFIIB repeat signature. GKsmeSIMAASILIGC
ChainResidueDetails
MGLY165-CYS180

site_idPS00959
Number of Residues9
DetailsHISTONE_H3_2 Histone H3 signature 2. PFqRLVREI
ChainResidueDetails
aPRO66-ILE74

site_idPS01030
Number of Residues27
DetailsRNA_POL_M_15KD RNA polymerases M / 15 Kd subunits signature. FCRDCNNMLypredkennrllfeCrtC
ChainResidueDetails
IPHE6-CYS32

site_idPS01110
Number of Residues14
DetailsRNA_POL_H_23KD RNA polymerases H / 23 Kd subunits signature. HELVPKHirLssDE
ChainResidueDetails
EHIS147-GLU160

site_idPS01111
Number of Residues15
DetailsRNA_POL_K_14KD RNA polymerases K / 14 to 18 Kd subunits signature. TkYErARiLGtRAlQ
ChainResidueDetails
FTHR86-GLN100

site_idPS01112
Number of Residues10
DetailsRNA_POL_N_8KD RNA polymerases N / 8 Kd subunits signature. IVPVrCFSCG
ChainResidueDetails
JILE2-GLY11

site_idPS01154
Number of Residues32
DetailsRNA_POL_L_13KD RNA polymerases L / 13 to 16 Kd subunits signature. FekEdHTLgNlIraeLlndrkVlfaaYkveHP
ChainResidueDetails
KPHE35-PRO66

site_idPS01166
Number of Residues13
DetailsRNA_POL_BETA RNA polymerases beta chain signature. GdKFASrHGQKGT
ChainResidueDetails
BGLY977-THR989

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0000250
ChainResidueDetails
cSER1
AASP483
AASP485
gSER1
dLYS12
dLYS17
hLYS2
hLYS9
hLYS12
hLYS17
AASP481

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: N6-acetyllysine => ECO:0000250
ChainResidueDetails
cLYS5
gLYS5
0CYS156
0CYS191
BCYS1185

site_idSWS_FT_FI3
Number of Residues4
DetailsMOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:P0C0S8
ChainResidueDetails
cLYS9
cLYS95
gLYS9
gLYS95

site_idSWS_FT_FI4
Number of Residues2
DetailsMOD_RES: N6-(2-hydroxyisobutyryl)lysine; alternate => ECO:0000250|UniProtKB:P0C0S8
ChainResidueDetails
cLYS36
gLYS36
ICYS103
ICYS106

site_idSWS_FT_FI5
Number of Residues4
DetailsMOD_RES: N6-(2-hydroxyisobutyryl)lysine => ECO:0000250|UniProtKB:P0C0S8
ChainResidueDetails
cLYS74
cLYS75
gLYS74
gLYS75
fLYS8
fLYS16
fLYS44
fLYS79

site_idSWS_FT_FI6
Number of Residues2
DetailsMOD_RES: N5-methylglutamine => ECO:0000250
ChainResidueDetails
cGLN104
gGLN104
fLYS12
fLYS20

site_idSWS_FT_FI7
Number of Residues2
DetailsMOD_RES: N6-glutaryllysine; alternate => ECO:0000250|UniProtKB:P0C0S8
ChainResidueDetails
cLYS118
gLYS118
fLYS31
fLYS91

site_idSWS_FT_FI8
Number of Residues8
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250
ChainResidueDetails
cLYS13
fSER47
cLYS15
cLYS119
gLYS13
gLYS15
gLYS119

site_idSWS_FT_FI9
Number of Residues4
DetailsMOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:P62805
ChainResidueDetails
bTYR51
bTYR88
fTYR51
fTYR88

site_idSWS_FT_FI10
Number of Residues2
DetailsMOD_RES: N6-glutaryllysine; alternate => ECO:0000250|UniProtKB:P62805
ChainResidueDetails
bLYS59
eLYS64
fLYS59
aLYS27
aLYS36
aLYS64
eLYS18
eLYS23
eLYS27
eLYS36

site_idSWS_FT_FI11
Number of Residues2
DetailsMOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:P62805
ChainResidueDetails
bLYS77
fLYS77

site_idSWS_FT_FI12
Number of Residues2
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in UFM1); alternate => ECO:0000250|UniProtKB:P62805
ChainResidueDetails
bLYS31
fLYS31

site_idSWS_FT_FI13
Number of Residues4
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate => ECO:0000250|UniProtKB:P62805
ChainResidueDetails
aLYS37
bLYS91
fLYS91

site_idSWS_FT_FI14
Number of Residues2
DetailsMOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:Q71DI3
ChainResidueDetails
aTYR41
eTYR41

site_idSWS_FT_FI15
Number of Residues4
DetailsMOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P84228
ChainResidueDetails
aLYS56
aLYS79
eLYS56
eLYS79

site_idSWS_FT_FI16
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q71DI3
ChainResidueDetails
aSER57
eSER57

site_idSWS_FT_FI17
Number of Residues4
DetailsMOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:Q71DI3
ChainResidueDetails
aTHR80
aTHR107
eTHR80
eTHR107

site_idSWS_FT_FI18
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P84243
ChainResidueDetails
aSER86
eSER86

site_idSWS_FT_FI19
Number of Residues2
DetailsMOD_RES: N6-glutaryllysine; alternate => ECO:0000250|UniProtKB:Q71DI3
ChainResidueDetails
aLYS115
eLYS115

site_idSWS_FT_FI20
Number of Residues2
DetailsMOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:Q71DI3
ChainResidueDetails
aLYS122
eLYS122

site_idSWS_FT_FI21
Number of Residues2
DetailsLIPID: S-palmitoyl cysteine => ECO:0000250|UniProtKB:Q71DI3
ChainResidueDetails
aALA110
eALA110

Catalytic Information from CSA
site_idMCSA1
Number of Residues1
DetailsM-CSA 788
ChainResidueDetails
BASP837metal ligand
AASP483metal ligand
AASP485metal ligand
AHIS1085proton acceptor, proton donor

226707

PDB entries from 2024-10-30

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