7ZRI

Cryo-EM structure of the KdpFABC complex in a nucleotide-free E1 conformation loaded with K+

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005886	cellular_component	plasma membrane
A	0006813	biological_process	potassium ion transport
A	0008556	molecular_function	P-type potassium transmembrane transporter activity
A	0030955	molecular_function	potassium ion binding
A	0031004	cellular_component	potassium ion-transporting ATPase complex
A	0071805	biological_process	potassium ion transmembrane transport
A	0098655	biological_process	monoatomic cation transmembrane transport
A	1903103	cellular_component	potassium:proton antiporter complex
B	0000287	molecular_function	magnesium ion binding
B	0005215	molecular_function	transporter activity
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005886	cellular_component	plasma membrane
B	0006813	biological_process	potassium ion transport
B	0008556	molecular_function	P-type potassium transmembrane transporter activity
B	0015662	molecular_function	P-type ion transporter activity
B	0016020	cellular_component	membrane
B	0016887	molecular_function	ATP hydrolysis activity
B	0031004	cellular_component	potassium ion-transporting ATPase complex
B	0046872	molecular_function	metal ion binding
B	0071805	biological_process	potassium ion transmembrane transport
B	0098655	biological_process	monoatomic cation transmembrane transport
B	1903103	cellular_component	potassium:proton antiporter complex
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0005886	cellular_component	plasma membrane
C	0006813	biological_process	potassium ion transport
C	0008556	molecular_function	P-type potassium transmembrane transporter activity
C	0016020	cellular_component	membrane
C	0031004	cellular_component	potassium ion-transporting ATPase complex
C	0071805	biological_process	potassium ion transmembrane transport
C	0098655	biological_process	monoatomic cation transmembrane transport
C	1903103	cellular_component	potassium:proton antiporter complex
D	0005886	cellular_component	plasma membrane
D	0006813	biological_process	potassium ion transport
D	0008556	molecular_function	P-type potassium transmembrane transporter activity
D	0031004	cellular_component	potassium ion-transporting ATPase complex
D	0043462	biological_process	regulation of ATP-dependent activity
D	0071805	biological_process	potassium ion transmembrane transport
D	0098655	biological_process	monoatomic cation transmembrane transport
D	1903103	cellular_component	potassium:proton antiporter complex

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	504
Details	TOPO_DOM: Cytoplasmic => ECO:0000269|PubMed:28636601

Chain	Residue	Details
B	MET1-ASN33
B	PHE81-THR222
B	PRO264-SER574
B	ILE632-ASN653
A	MET436-PRO479
A	ALA553-SER557

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site_id	SWS_FT_FI2
Number of Residues	131
Details	TRANSMEM: Helical => ECO:0000269|PubMed:28636601, ECO:0007744|PDB:5MRW

Chain	Residue	Details
B	PRO34-SER55
A	PRO525-VAL552
B	ALA62-ASN80
B	ILE223-PHE242
B	VAL252-ILE263
B	LEU575-PHE595
B	PRO613-LEU631
B	LEU654-VAL678
A	LYS415-ALA435
A	PHE480-MET501

---

site_id	SWS_FT_FI3
Number of Residues	32
Details	TOPO_DOM: Periplasmic => ECO:0000269|PubMed:28636601

Chain	Residue	Details
B	GLY56-ASN61
B	SER243-SER251
B	ALA596-SER612
B	CYS679-VAL682
A	ALA502-GLY524

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site_id	SWS_FT_FI4
Number of Residues	1
Details	ACT_SITE: 4-aspartylphosphate intermediate => ECO:0000255|HAMAP-Rule:MF_00285, ECO:0000269|PubMed:1474895

Chain	Residue	Details
B	ASN307

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site_id	SWS_FT_FI5
Number of Residues	3
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00285, ECO:0000269|PubMed:16354672, ECO:0007744|PDB:2A00, ECO:0007744|PDB:2A29

Chain	Residue	Details
B	ASP344
B	PHE377
B	LYS395

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site_id	SWS_FT_FI6
Number of Residues	1
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00285, ECO:0000269|PubMed:16354672, ECO:0007744|PDB:2A00

Chain	Residue	Details
B	GLU348

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site_id	SWS_FT_FI7
Number of Residues	2
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00285

Chain	Residue	Details
B	ASP518
B	ASP522

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site_id	SWS_FT_FI8
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000269|PubMed:28636601, ECO:0000269|PubMed:30478378

Chain	Residue	Details
B	SEP162

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