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7ZLI

Cryo-EM structure of C-mannosyltransferase CeDPY19, in complex with Dol25-P-Man and bound to CMT2-Fab and anti-Fab nanobody

Functional Information from GO Data
ChainGOidnamespacecontents
A0000030molecular_functionmannosyltransferase activity
A0005737cellular_componentcytoplasm
A0005783cellular_componentendoplasmic reticulum
A0005789cellular_componentendoplasmic reticulum membrane
A0005975biological_processcarbohydrate metabolic process
A0007399biological_processnervous system development
A0016020cellular_componentmembrane
A0016740molecular_functiontransferase activity
A0016757molecular_functionglycosyltransferase activity
A0018406biological_processobsolete protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan
A0030154biological_processcell differentiation
A0048471cellular_componentperinuclear region of cytoplasm
L0002250biological_processadaptive immune response
L0002376biological_processimmune system process
L0005576cellular_componentextracellular region
L0005886cellular_componentplasma membrane
L0016020cellular_componentmembrane
L0019814cellular_componentimmunoglobulin complex
Functional Information from PROSITE/UniProt
site_idPS00290
Number of Residues7
DetailsIG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH
ChainResidueDetails
LTYR193-HIS199
HTYR209-HIS215

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI2
Number of Residues200
DetailsTransmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

240971

PDB entries from 2025-08-27

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