Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 948 |
| Details | TOPO_DOM: Periplasmic => ECO:0000305 |
| Chain | Residue | Details |
| A | ALA22-PHE254 | |
| A | THR844-GLY848 | |
| A | GLY941-LYS949 | |
| A | GLY989-VAL990 | |
| A | ASP1024-ARG1032 | |
| A | ASN1067-GLN1073 | |
| A | GLN1123-ASP1124 | |
| A | PHE1167 | |
| B | ALA22-PHE254 | |
| B | GLY404-LEU416 | |
| B | GLY491-PRO494 | |
| A | GLY404-LEU416 | |
| B | GLY529-PRO540 | |
| B | THR572-LEU577 | |
| B | PHE616-GLY617 | |
| B | THR650-THR670 | |
| B | GLY767-PRO768 | |
| B | ALA799-ILE802 | |
| B | THR844-GLY848 | |
| B | GLY941-LYS949 | |
| B | GLY989-VAL990 | |
| B | ASP1024-ARG1032 | |
| A | GLY491-PRO494 | |
| B | ASN1067-GLN1073 | |
| B | GLN1123-ASP1124 | |
| B | PHE1167 | |
| C | ALA22-PHE254 | |
| C | GLY404-LEU416 | |
| C | GLY491-PRO494 | |
| C | GLY529-PRO540 | |
| C | THR572-LEU577 | |
| C | PHE616-GLY617 | |
| C | THR650-THR670 | |
| A | GLY529-PRO540 | |
| C | GLY767-PRO768 | |
| C | ALA799-ILE802 | |
| C | THR844-GLY848 | |
| C | GLY941-LYS949 | |
| C | GLY989-VAL990 | |
| C | ASP1024-ARG1032 | |
| C | ASN1067-GLN1073 | |
| C | GLN1123-ASP1124 | |
| C | PHE1167 | |
| A | THR572-LEU577 | |
| A | PHE616-GLY617 | |
| A | THR650-THR670 | |
| A | GLY767-PRO768 | |
| A | ALA799-ILE802 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1023 |
| Details | TRANSMEM: Beta stranded => ECO:0000269|PubMed:35943982 |
| Chain | Residue | Details |
| A | SER255-ARG268 | |
| A | SER602-ALA615 | |
| A | VAL618-ARG630 | |
| A | GLN639-ALA649 | |
| A | PHE671-LYS682 | |
| A | GLY754-LEU766 | |
| A | VAL769-THR779 | |
| A | MET789-VAL798 | |
| A | PHE803-SER814 | |
| A | ALA832-VAL843 | |
| A | LEU849-VAL860 | |
| A | ARG378-SER403 | |
| A | SER932-ALA940 | |
| A | ASP950-VAL960 | |
| A | VAL977-VAL988 | |
| A | ALA991-THR1002 | |
| A | GLY1015-THR1023 | |
| A | PRO1033-ASN1046 | |
| A | TYR1053-LEU1066 | |
| A | THR1074-GLN1086 | |
| A | ARG1109-TYR1122 | |
| A | LEU1125-ASP1138 | |
| A | GLN417-VAL428 | |
| A | ALA1154-ASN1166 | |
| B | SER255-ARG268 | |
| B | ARG378-SER403 | |
| B | GLN417-VAL428 | |
| B | ASN472-VAL490 | |
| B | VAL495-GLY500 | |
| B | GLY520-ASP528 | |
| B | GLN541-ARG549 | |
| B | VAL562-ILE571 | |
| B | THR578-ARG588 | |
| A | ASN472-VAL490 | |
| B | SER602-ALA615 | |
| B | VAL618-ARG630 | |
| B | GLN639-ALA649 | |
| B | PHE671-LYS682 | |
| B | GLY754-LEU766 | |
| B | VAL769-THR779 | |
| B | MET789-VAL798 | |
| B | PHE803-SER814 | |
| B | ALA832-VAL843 | |
| B | LEU849-VAL860 | |
| A | VAL495-GLY500 | |
| B | SER932-ALA940 | |
| B | ASP950-VAL960 | |
| B | VAL977-VAL988 | |
| B | ALA991-THR1002 | |
| B | GLY1015-THR1023 | |
| B | PRO1033-ASN1046 | |
| B | TYR1053-LEU1066 | |
| B | THR1074-GLN1086 | |
| B | ARG1109-TYR1122 | |
| B | LEU1125-ASP1138 | |
| A | GLY520-ASP528 | |
| B | ALA1154-ASN1166 | |
| C | SER255-ARG268 | |
| C | ARG378-SER403 | |
| C | GLN417-VAL428 | |
| C | ASN472-VAL490 | |
| C | VAL495-GLY500 | |
| C | GLY520-ASP528 | |
| C | GLN541-ARG549 | |
| C | VAL562-ILE571 | |
| C | THR578-ARG588 | |
| A | GLN541-ARG549 | |
| C | SER602-ALA615 | |
| C | VAL618-ARG630 | |
| C | GLN639-ALA649 | |
| C | PHE671-LYS682 | |
| C | GLY754-LEU766 | |
| C | VAL769-THR779 | |
| C | MET789-VAL798 | |
| C | PHE803-SER814 | |
| C | ALA832-VAL843 | |
| C | LEU849-VAL860 | |
| A | VAL562-ILE571 | |
| C | SER932-ALA940 | |
| C | ASP950-VAL960 | |
| C | VAL977-VAL988 | |
| C | ALA991-THR1002 | |
| C | GLY1015-THR1023 | |
| C | PRO1033-ASN1046 | |
| C | TYR1053-LEU1066 | |
| C | THR1074-GLN1086 | |
| C | ARG1109-TYR1122 | |
| C | LEU1125-ASP1138 | |
| A | THR578-ARG588 | |
| C | ALA1154-ASN1166 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1284 |
| Details | TOPO_DOM: Extracellular => ECO:0000305 |
| Chain | Residue | Details |
| A | THR269-ALA377 | |
| A | ASN861-THR931 | |
| A | TYR961-SER976 | |
| A | ASN1003-ARG1014 | |
| A | ARG1047-ASN1052 | |
| A | ASN1087-ASN1108 | |
| A | LEU1139-PRO1153 | |
| B | THR269-ALA377 | |
| B | THR429-GLY471 | |
| B | GLN501-ARG519 | |
| B | SER550-GLY561 | |
| A | THR429-GLY471 | |
| B | ASP589-PRO601 | |
| B | PRO631-VAL638 | |
| B | ILE683-ILE753 | |
| B | GLY780-ARG788 | |
| B | ASN815-ASP831 | |
| B | ASN861-THR931 | |
| B | TYR961-SER976 | |
| B | ASN1003-ARG1014 | |
| B | ARG1047-ASN1052 | |
| B | ASN1087-ASN1108 | |
| A | GLN501-ARG519 | |
| B | LEU1139-PRO1153 | |
| C | THR269-ALA377 | |
| C | THR429-GLY471 | |
| C | GLN501-ARG519 | |
| C | SER550-GLY561 | |
| C | ASP589-PRO601 | |
| C | PRO631-VAL638 | |
| C | ILE683-ILE753 | |
| C | GLY780-ARG788 | |
| C | ASN815-ASP831 | |
| A | SER550-GLY561 | |
| C | ASN861-THR931 | |
| C | TYR961-SER976 | |
| C | ASN1003-ARG1014 | |
| C | ARG1047-ASN1052 | |
| C | ASN1087-ASN1108 | |
| C | LEU1139-PRO1153 | |
| A | ASP589-PRO601 | |
| A | PRO631-VAL638 | |
| A | ILE683-ILE753 | |
| A | GLY780-ARG788 | |
| A | ASN815-ASP831 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 57 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:35577074, ECO:0007744|PDB:7ZGY |
| Chain | Residue | Details |
| A | ASP274 | |
| A | ASP446 | |
| A | GLU449 | |
| A | ASP513 | |
| A | ASN515 | |
| A | ARG549 | |
| A | GLY551 | |
| A | ASP553 | |
| A | GLY559 | |
| A | SER622 | |
| A | GLY716 | |
| A | ASP276 | |
| B | ASP274 | |
| B | ASP276 | |
| B | ARG305 | |
| B | PHE308 | |
| B | ASP310 | |
| B | GLU381 | |
| B | ASP438 | |
| B | ASN442 | |
| B | LYS444 | |
| B | ASP446 | |
| A | ARG305 | |
| B | GLU449 | |
| B | ASP513 | |
| B | ASN515 | |
| B | ARG549 | |
| B | GLY551 | |
| B | ASP553 | |
| B | GLY559 | |
| B | SER622 | |
| B | GLY716 | |
| C | ASP274 | |
| A | PHE308 | |
| C | ASP276 | |
| C | ARG305 | |
| C | PHE308 | |
| C | ASP310 | |
| C | GLU381 | |
| C | ASP438 | |
| C | ASN442 | |
| C | LYS444 | |
| C | ASP446 | |
| C | GLU449 | |
| A | ASP310 | |
| C | ASP513 | |
| C | ASN515 | |
| C | ARG549 | |
| C | GLY551 | |
| C | ASP553 | |
| C | GLY559 | |
| C | SER622 | |
| C | GLY716 | |
| A | GLU381 | |
| A | ASP438 | |
| A | ASN442 | |
| A | LYS444 |
